Search clinical trials for: cellular response

Total 16150 results

IRCCS Sacro Cuore Don Calabria di Negrar

Recruiting

Understanding Adaptive Immune Response After COVID-19 Vaccination Boosters to Improve Vaccination Strategies in Vulnerable Groups. (COVaxFragile)

COVID-19

Italy
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Brain Blood Flow Responses to Stress: Sex Differences

Cerebrovascular Disorders

United States
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance (FIL_FollVax22)

Follicular Lymphoma

Italy
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Technische Universität Dresden; Canadian Critical Care Trials Group and other collaborators

Recruiting

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock (UC-CISSII)

Pathologic Processes | Infections | Sepsis | Systemic Inflammatory Response Syndrome | Inflammation | Shock | Septic Shock

Canada
Hospices Civils de Lyon

Recruiting

Protection Response to Cellular Stress in BPAN's Patient Study (REP-BPAN)

Children and Adults With BPAN Carrying Pathogenic Variants of WDR45

France
National Cancer Institute (NCI)

Recruiting

Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer

Neoplasms | Esophageal Neoplasms | Esophagus Cancer | Esophagus Neoplasm | Neoplasms, Esophageal | Esophageal Cancer (EsC)

United States
Hospital for Special Surgery, New York

Recruiting

Analysis of T and B Cell Repertoire Changes in Response to Orencia® (Abatacept) in Rheumatoid Arthritis

Rheumatoid Arthritis

United States
National Cancer Institute (NCI)

Recruiting

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Non-Small Cell Lung Carcinoma | Carcinomas

United States
University Hospital, Basel, Switzerland
Novartis; Schweizerische Stiftung für die Erforschung der Muskelkrankheiten

Recruiting

Predictive Factors for Treatment Response in Patients With Newly-diagnosed Polymyalgia Rheumatica and Giant Cell Arteritis

Polymyalgia Rheumatica (PMR) | Giant Cell Arteritis (GCA)

Switzerland
MRC/UVRI and LSHTM Uganda Research Unit
International AIDS Vaccine Initiative

Recruiting

Feasibility of Identifying, Enrolling and Following Acute and Early HIV-1 Infected Individuals. (KILGORIS)

Acute Human Immunodeficiency Virus Type I Infection

Uganda
Lei Li

Recruiting

Tislelizumab and Radiotherapy for Recurrent Cervical Cancer

Recurrent Cervical Carcinoma | Radiotherapy | Immunotherapy | Survival Outcomes | Immune Checkpoint Inhibitors | Objective Response Rate | Metastatic Cervical Carcinoma | Tislelizumab | Persistent Cervical Carcinoma | Anti-programmed Cell Death Receptor 1

China
Institut Pasteur
Janssen Biotech, Inc.

Recruiting

The Role of IL-23 in Chronic Inflammatory Disease: Exploring the Cellular and Molecular Targets of IL-23 Signaling in Peripheral and Axial Spondyloarthritis (SpA23)

Spondyloarthritis

France
Dongzhimen Hospital, Beijing

Recruiting

Characteristics of LKDS and PBSS of KOA Based on the Enhancement of Inflammatory Response by TGF-β/Smad Pathway Inhibited

Syndrome | Knee Osteoarthritis | Traditional Chinese Medicine

China
St. Jude Children's Research Hospital

Recruiting

Evaluating Immune Response to COVID-19 Vaccines in Patients With Cancer, Transplant or Cellular Therapy Recipients

Cancer | Hematologic Malignancy | Solid Organ Transplant | Hematopoietic Cell Transplant | Solid Tumor Malignancy | Hematopoietic System--Cancer | Transplant-Related Cancer | Cellular Therapy

United States
Institut Pasteur
Janssen Biotech, Inc.

Recruiting

Exploration of the Cellular and Molecular Mechanisms in Patients Receiving Biotherapies Targeting the IL-23/IL-17 Axis in Cutaneous Psoriasis (Pso23)

Psoriasis

France
University of Pennsylvania
National Institute of Allergy and Infectious Diseases (NIAID); Stanford University and other collaborators

Recruiting

Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults

Influenza, Human

United States
Gérond'if

Recruiting

Humoral and Cellular Responses to Vaccination Against Coronavirus Disease 2019 (COVID-19) in the Very Elderly Living in Geriatric Institutions (COGEVAX-BIO)

Elderly People Institutionalized in Long-term Care Services

France
University Hospital, Clermont-Ferrand

Recruiting

Monitoring of the Post-vaccination Immune Response to COVID-19 Among Hospital Staff (COVIDIM)

Hospital Staff | Vaccined Againt COVID-19

France
Plexision

Recruiting

Immunity After COVID-19 Vaccination

Immunity to COVID-19

United States
National Institute on Aging (NIA)

Recruiting

A Clinical Observational Study of SARS-CoV-2 Specific CD8 T-Cell Responses to COVID-19 Vaccines in Humans

COVID-19

United States
Technische Universität Dresden
Charite University, Berlin, Germany; Klinikum St. Georg gGmbH; Universitätsklinikum... and other collaborators

Recruiting

Saxon SARS-CoV-2 Infection and Vaccination Study in Dialysis Patients, Solid Organ Recipients and Staff (DIA-Vacc)

Immune Response | SARS-CoV-2 Infection | Immunosuppression | Active Immunization

Germany
Ottawa Hospital Research Institute
Ontario Institute for Cancer Research; Intensity Therapeutics, Inc.

Recruiting

INVINCIBLE TRIAL: Intratumoral INT230-6 in Breast Cancer

Breast Cancer

Canada
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Transplantation of hAMSCs for Woman With DOR

Diminished Ovarian Response

China
University Hospital, Lille
Universite du Littoral Cote d'Opale

Recruiting

Development of Cellular Models for Osteoblast Response Study to Adipocytic Secretions in an Osteoporosis Context. (ROSA)

Osteoporosis

France
Fred Hutchinson Cancer Center
Swedish Orphan Biovitrum

Recruiting

Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy

B-Cell Non-Hodgkin Lymphoma

United States
University of Regensburg
Krankenhaus Barmherzige Brüder, Regensburg

Recruiting

Longitudinal Study of CRS/HIPEC for Peritoneal Carcinomatoses (CRS/HIPEC)

Peritoneal Carcinomatosis

Germany
Instituto Nacional de Ciencias Medicas y Nutricion...
Hospital General Dr. Manuel Gea González

Recruiting

Comparative Analysis of the Th17 Cellular Response in Active and Inactive Pemphigus Vulgaris Patients

Autoimmune Diseases | Bullous Dermatoses | Pemphigus Vulgaris

Mexico
Prof. Dr. Paul Brinkkoetter
German Research Foundation; Medical Faculty and the Faculty of Natural Sciences... and other collaborators

Recruiting

The FOrMe Registry (The German Focal Segmental Glomerulosclerosis and Minimal Change Disease Registry) (FOrMe)

Glomerulosclerosis, Focal Segmental | Minimal Change Disease | Idiopathic Nephrotic Syndrome

Germany
National Institute of Allergy and Infectious Diseases...

Recruiting

Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in People With Idiopathic CD4 T Cell Lymphocytopenia

Idiopathic CD4 T Cell Lymphocytopenia

United States
Finnish Institute for Health and Welfare
Hospital District of Helsinki and Uusimaa

Recruiting

Immune Responses in Health Care Personnel

Influenza

Finland
M.D. Anderson Cancer Center

Active, not recruiting

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Untreated Adult Acute Lymphoblastic Leukemia | Accelerated Phase Chronic Myelogenous Leukemia,... and other conditions

United States
University College, London
Cancer Research UK; Cancer Research UK & UCL Cancer Trials Centre

Completed

Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma

Lymphoma

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Immunization With the H1N1 or Seasonal Influenza Vaccines

Influenza | Healthy Volunteers

United States
Henry Ford Health System

Completed

Response to SARS-CoV-2 Vaccine in Stem Cell Transplant and Cellular Therapy Patients

Hematologic Disorders and Bone Marrow Failure, Hematopoietic Stem Cell Transplantation (HSCT) or Cellular Therapy (CART)

United States
IRCCS San Raffaele Roma

Completed

Spike-specific Cellular Immune Response After COVID-19 Vaccination (RIS-COV)

Immune Response | COVID19 | Vaccination

Italy
Matti Sällberg

Completed

A Randomized, Phase I Study of DNA Vaccine OC-007 as a Booster Dose of COVID-19 Vaccine (OpenCorona1)

COVID-19 Respiratory Infection | COVID-19 Vaccine Adverse Reaction

Sweden
Incyte Corporation

Completed

A Study of Itacitinib for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy

Cytokine Release Syndrome

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Terminated

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions

United States
Edoardo Melilli

Withdrawn

Introduction of mTor Inhibitors and the Activation of the Cytomegalovirus (CMV) -Specific Cellular Immune Response (ACTIVA)

Kidney Transplantation | Cytomegalovirus Infections

Spain
Andrei Iagaru
General Electric

Completed

68-Ga PSMA 11 PET/MRI and 68-Ga RM2 PET/MRI for Evaluation of Prostate Cancer Response to HIFU Therapy

Prostate Cancer

United States
Banc de Sang i Teixits
Hospital Universitario La Fe; Vall d'Hebron Institute of Oncology

Completed

Virus-specific Activated T Lymphocytes From a Donor in Hematopoietic Progenitor Transplanted Patients

CMV Viremia | Immunosuppression-related Infectious Disease

Spain
Assistance Publique - Hôpitaux de Paris

Completed

Covid-19 Vaccine Response in Heart Transplant Recipients (COVHEART)

Heart Transplantation | COVID-19 Vaccine | COVID-19 Virus Infection

France
Mario Negri Institute for Pharmacological Research
Belfast Health and Social Care Trust; National University of Ireland, Galway... and other collaborators

Active, not recruiting

NEPHSTROM for Diabetic Kidney Disease (NEPHSTROM)

Diabetic Kidney Disease

Ireland, Italy, United Kingdom
Shanghai Jiao Tong University School of Medicine

Completed

Neoadjuvant Toripalimab and Paclitaxel/Cisplatin on Pathological Response in Oral Squamous Cell Carcinoma Patients

Oral Cancer | Induction Chemotherapy | Programmed Cell Death 1 Inhibitor | Inductive Therapy

China
Sahlgrenska University Hospital, Sweden

Completed

Impact of Cardiopulmonary Bypass Flow on Renal Oxygenation, Blood Flow and Tubular Injury (ICAROX2)

Renal Failure | Inflammatory Response | Hemolysis | Cardiopulmonary Bypass | Extracorporeal Circulation; Complications | Circulation Disorder | Renal Plasma Flow, Effective

Sweden
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes (TRIABETES)

Obesity | Type 2 Diabetes Mellitus

United States
Centre Georges Francois Leclerc

Completed

Mechanisms of Anti COVID-19 Humoral and Cellular Immune Response After Vaccination in a Sample of Patients and Salaried Staff From a French Anti-cancer Center (CANSEROVAX)

Cancer

France
Merck Sharp & Dohme LLC

Active, not recruiting

Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)

Hepatocellular Carcinoma

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, China, Denmark, France, Germany, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic of, Malaysia, New Zealand, Norway, Poland, Russian Federation, Spai... and more
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
Gazi University
Seroxo Ltd

Completed

Can Measurement of Neutrophil-derived ROS Production be a Novel Biomarker of Sepsis? (LIT-sepsis)

Infections | Sepsis | Septic Shock

Turkey

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