Search clinical trials for: clinical biomarker

Total 67021 results

AAADRS Clinical Research Center

Recruiting

FeNO as a Marker of Allergic Reactions to OFC and Response of OMA Treatment in Multiple FA

Food Allergy

United States
AstraZeneca

Not yet recruiting

A Randomised, Double-blind, Parallel Group, Placebo Controlled, 4-Week, Phase II Study to Evaluate the Effect of AZD4604 on Airway Inflammation and Biomarkers in Adults With Asthma (ARTEMISIA)

Asthma

Canada, Denmark, Germany, Spain, United Kingdom
University of Southern Denmark
Odense University Hospital; Sygehus Lillebaelt; Sonderborg Hospital; Esbjerg Hospital

Not yet recruiting

Clinical Biomarker of Paclitaxel-induced Peripheral Neuropathy

Chemotherapy-induced Peripheral Neuropathy
AstraZeneca

Recruiting

A Translational Study to Describe Clinical Characteristics, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes in Chinese Population

Asthma

China
Cuibai Wei，Clinical Professor
Chongqing Medical University; First Hospital of Shijiazhuang City; Tianjin Huanhu... and other collaborators

Not yet recruiting

Exploring the Diagnostic Biomarkers of Cognitive Disorders in China

Dementia | Biomarkers
Imperial College London

Not yet recruiting

Identifying Wearable Biomarkers to Monitor Dietary Intake (FoodSense)

Healthy Volunteers | Blood Glucose | Wearables | Metabolism | Energy Intake | Digestion | Dietary Intake Assessment

United Kingdom
Max-Planck-Institute of Psychiatry

Recruiting

Deep Phenotyping for Clinical Inferring Response in Treatment Resistant Depression (DECIDE)

Depressive; Disorder, Major, Single Episode, Major, With Psychotic Symptoms | Depressive; Disorder, Major, Single Episode, Major (Without Psychotic Symptoms) | Depressive Disorder, Major, Recurrent, With Psychotic Symptoms | Depressive Disorder, Major, Recurrent, Without Psychotic Symptoms and other conditions

Germany
Institute of Cancer Research, United Kingdom
Case45 Ltd

Not yet recruiting

Deployment and Clinical Evaluation of an AI-powered Digital Oncology Biomarker Tool to guidE Treatment in TNBC (AIDOBE)

Triple Negative Breast Cancer
Mayo Clinic

Recruiting

DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Metastatic Breast Cancer Patients

Metastatic Breast Cancer | HER2-negative Breast Cancer | Hormone-receptor-positive Breast Cancer

United States
Region Skane

Recruiting

Selective Head-and-neck Cooling on Biomarker Levels and Symptom Rating Following a Boxing Bout

Repetitive Head Impact | Selective Head and Neck Cooling

Sweden
AIO-Studien-gGmbH
Merck Sharp & Dohme LLC

Not yet recruiting

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome (HEAT)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx

Germany
University of Campania "Luigi Vanvitelli"
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico; University of Milan and other collaborators

Recruiting

The PRO-FUTURE Project (PRO-FUTURE)

Chronic Kidney Diseases | Ureteropelvic Junction Obstruction

Italy
Presage Biosciences
AstraZeneca

Recruiting

PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC

Head and Neck Squamous Cell Carcinoma

United States
Alnylam Pharmaceuticals

Recruiting

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Hereditary Amyloidosis, Transthyretin-Related | Asymptomatic Carrier State

France
Mayo Clinic

Recruiting

Oropharynx (OPX) Biomarker Trial

Oropharyngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Oropharyngeal (p16-Negative)... and other conditions

United States
Barretos Cancer Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo; Farmoquimica S.A.; Hospital...

Not yet recruiting

Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated With Imiquimod

Biomarkers | HSIL, High-Grade Squamous Intraepithelial Lesions | Vaginal Microbiome
Mayo Clinic
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Recruiting

Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Wuhan Union Hospital, China

Not yet recruiting

The Clinical Significance of CT-based Biomarkers in the Classification and Prognosis of Bronchiectasis

Bronchiectasis

China
Casa Sollievo della Sofferenza IRCCS
Ministry of Health, Italy

Recruiting

Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis (STEMALS) (STEMALS)

Amyotrophic Lateral Sclerosis

Italy
Mayo Clinic

Recruiting

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

Brain Neoplasms

United States
European Institute of Oncology

Recruiting

Early Identification of Cardiac Involvement in Patients With Carcinoid: Clinical and Prognostic Implications

Neuroendocrine Tumors

Italy
Region Örebro County
Karolinska University Hospital; Karolinska Institutet; Sahlgrenska University... and other collaborators

Recruiting

A Two Year Longitudinal Clinical Study of Neurocognitive and Psychiatric Symptoms in Post COVID-19 Patients (PASC24)

COVID-19

Sweden
Radboud University Medical Center
Maastricht University Medical Center

Recruiting

TREAT Study - Improving the Interpretation of Troponin Concentrations Following Exercise and Their Clinical Significance (TREAT)

Coronary Artery Disease

Netherlands
Massachusetts General Hospital
BioSensics

Recruiting

Physical Activity Monitoring in Myasthenia Gravis

Myasthenia Gravis

United States
Queen Mary University of London
University of Zurich

Not yet recruiting

Influence of Timing of Implant Placement on Early Healing Molecular Events

Healing Wound | Biomarkers | Dental Implant | Saliva

United Kingdom
Baylor College of Medicine
Doris Duke Charitable Foundation

Recruiting

Clinical and Molecular Biomarker Studies in RAI1 (Retinoic Acid-Induced 1) -Related Disorders

RAI1 Gene 17P11.2 Deletion+Duplication

United States
PlaqueTec Ltd
Royal Papworth Hospital

Recruiting

Liquid Biopsy System Intracoronary Blood Sampling and Analysis to Characterise Disease Biomarkers in Patients With Coronary Disease (BIOPATTERN)

Coronary Artery Disease

United Kingdom
Nucleix Ltd.

Recruiting

Lung EpiCheck Biomarkers Development Study

Lung Cancer

United States, Israel, Hungary, Netherlands
Anavex Life Sciences Corp.
Cognitive Research Corporation; COGNISION; Hassman Research Institute

Recruiting

A Study of ANAVEX3-71 in Adults With Schizophrenia (SZ-001)

Schizophrenia

United States
AstraZeneca

Recruiting

Treatment and Biomarker Testing Patterns,Treatment Outcomes in a/m NSCLC With and Without Actionable Genomic Alterations

Non-small-cell Lung Cancer

Russian Federation
Pediatric Clinical Research Platform

Recruiting

t-BIOMAP : Prospective Paediatric Cohort Study of Blood Biomarkers in mTBI (t-BIOMAP)

Mild Traumatic Brain Injury

Switzerland
Shanghai Zhongshan Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Dose Escalation and Expansion Clinical Trial of Irinotecan Liposome Combined With Oxaliplatin and 5-FU/LV Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Nan Shen
Novartis

Not yet recruiting

Disease and Biomarker Profiling of Chinese Lupus Nephritis

Characterize the Molecular Profile of Lupus Nephritis(LN) Patients to Understand Themechanism(s)Contributing to Patient Responsiveness to Soc | Integrated Analysis of LN Patient Molecular Profiling and Clinical Annotations to Understand LNdisease Heterogeneity for Disease Endotype | Validate the Association of the Candidate Biomarker Panel Proposed in Table 3-1 With LN Diseasemonitoring
Neurosoft Bioelectronics SA
UMC Utrecht; European Research Council

Not yet recruiting

Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid ) (EpiGrid)

Focal Epilepsy | Intraoperative Monitoring

Netherlands
Assistance Publique - Hôpitaux de Paris

Recruiting

Identification and Clinical Validation of Biomarkers Associated With Clinical Severity in Adults Infected With RSV (ARF-RSV)

Respiratory Syncytial Virus Infections

France
Altria Client Services LLC
Celerion

Recruiting

Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

Tobacco Use

United States
St. Joseph's Hospital and Medical Center, Phoenix
Texas Tech University

Not yet recruiting

MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Cognitive Dysfunction | Neurodegenerative Disease, Hereditary | Cognitive Impairment, Mild | Amyloid Plaque | Inflammation, Brain
University of Baghdad

Not yet recruiting

Efficacy of Oral Hygiene Instructions on Proinflammatory Cytokines Among Cigarette Smokers and Individuals Vaping Electronic Cigarettes During Plaque Induced Gingivitis (Clinical Trial)

Electronic Cigarette Use | Plaque Induced Gingivitis
Biruni University

Not yet recruiting

Effect of Non-Surgical Periodontal Treatment on Gingival Crevicular Fluid and Serum Biomarker Levels

Healthy | Periodontitis | Gingivitis

Turkey
IRCCS San Raffaele
IRCCS National Neurological Institute "C. Mondino" Foundation

Recruiting

Exploring Brain Molecular Imaging and Blood Biomarkers in Subjects With Glucocerebrosidase Mutations: Toward a Precision Medicine Approach to Characterize Parkinson's Disease Clinical Trajectories

Parkinson Disease

Italy
Delfi Diagnostics Inc.

Recruiting

Implementing Fragmentomics Into Real World Screening IntervenTions to Evaluate Clinical Utility Among Individuals With Elevated Risk for Lung Cancer (FIRSTLungL301)

Lung Cancer

United States
Duke University
Memorial Sloan Kettering Cancer Center; University of Wisconsin, Madison

Recruiting

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials (ARCTIC)

Prostate Cancer | Castration-resistant Prostate Cancer | Prostate Adenocarcinoma | Prostate Cancer Metastatic

United States
AstraZeneca

Not yet recruiting

NIS Study Determining Prevalence of HER2-low in Metastatic Breast Cancer Patients (iRetroBC)

HER2-negative
Bernie Eigl
Lady Davis Institute; Vancouver Prostate Centre; Bladder Cancer Canada

Recruiting

A Study to Compare the Results of FGFR Testing by Either ctDNA Blood Testing or Standard Tumor Tissue Testing

Metastatic Urothelial Carcinoma | Metastatic Bladder Cancer

Canada
Singapore Institute for Clinical Sciences
OBVIO HEALTH USA, Inc.

Recruiting

Novel Objective Digital Biomarkers for Assessing Sub-clinical Mood Disturbances in the Singaporean Population

Mood

Singapore
Medical College of Wisconsin

Not yet recruiting

Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer

Breast Cancer

United States
Children's Hospital of Eastern Ontario
The Hospital for Sick Children; Hannover Medical School; MOUNT SINAI HOSPITAL; St... and other collaborators

Recruiting

Early-life MRI Biomarkers of Longer-term Respiratory Morbidity in Infants Born Extremely Preterm (EMBLEM) (EMBLEM)

Lung Function | BPD - Bronchopulmonary Dysplasia

Canada
Hospices Civils de Lyon

Recruiting

Validation of Biomarkers Performance to Reduce Antibiotics overUse in newBorns With Suspected Clinical Signs of InfectionS (RUBIS)

Neonatal Late Onset Sepsis

France
Shanghai 10th People's Hospital

Recruiting

Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome

Polycystic Ovary Syndrome

China
Alexandria University

Recruiting

Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity

Nerve Degeneration | Neurotoxicity | Nerve Injury | Genotoxicity | Neuroinflammatory Response | Nerve Damage

Egypt

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