Search clinical trials for: daptomycin

Total 109 results

Chang Gung Memorial Hospital

Not yet recruiting

Preoperative Daptomycin Prophylaxis in Two-Stage Exchange Arthroplasty: A Prospective, Randomized, Double-Blinded Trial

Periprosthetic Joint Infection

Taiwan
University of Melbourne
Radboud University Medical Center; Sunnybrook Health Sciences Centre; UMC Utrecht and other collaborators

Recruiting

Staphylococcus Aureus Network Adaptive Platform Trial (SNAP)

Staphylococcus Aureus Bacteremia

Australia, New Zealand, Canada, Singapore, Netherlands, Israel
Hospices Civils de Lyon

Recruiting

Pharmacokinetics and Toxicodynamics of Daptomycin in Bone and Joint Infections (PKTOXDAP)

Bone and Joint Infection | Dactinomycin Adverse Reaction

France
Vancouver Island Health Authority

Recruiting

Ceftriaxone as Home IV for Staph Infections

Abscess | Staphylococcal Infections | Diabetic Foot Infection | Osteomyelitis | Vertebral Osteomyelitis | CNS Infection | Septic Arthritis | Coagulase Negative Staphylococcal Infection

Canada
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
Centre Hospitalier Universitaire Dijon

Recruiting

Adjunction of Daptomycin for the Treatment of Pneumococcal Meningitis (AddaMAP)

Pneumococcal Meningitis

France
Bayer

Active, not recruiting

Drug Use Investigation of Kovaltry in Hemophilia A Patients

Hemophilia A

Japan
Ruhr University of Bochum

Terminated

Application of Daptomycin in MRSA Infected Diabetic Foot in Comparison to Vancomycin Treatment

Diabetic Foot

Germany
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
National Institute of Allergy and Infectious Diseases...

Completed

DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus Bacteremia

Staphylococcal Bacteraemia

United States, Canada
West Virginia University

Enrolling by invitation

Comparing Oral Versus Parenteral Antimicrobial Therapy (COPAT)

Skin and Soft Tissue Infection | Gastrointestinal Infection | Pulmonary Infection | Bone and Joint Infection | Endovascular Infection | Genitourinary Infection

United States
Vinay Badhwar

Enrolling by invitation

Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) (OPTIMAL)

Endocarditis

United States
Basilea Pharmaceutica
Department of Health and Human Services

Completed

Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia

Staphylococcus Aureus Bacteremia

Israel, United States, Georgia, Russian Federation, Ukraine, Colombia, Argentina, Bulgaria, Germany, Greece, Italy, Mexico, Panama, Serbia, South Africa, Spain, Turkey
Hospital Universitari de Bellvitge
Baxter Healthcare Corporation

Completed

Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®)

Sepsis | Acute Kidney Injury | Hemodiafiltration

Spain
Infectious Diseases Physicians, Inc.
Johns Hopkins University

Completed

Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections

Prosthetic Joint Infection | Osteomyelitis | Septic Arthritis | Bone Infection | Joint Infection

United States
Henry Ford Health System

Terminated

Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients (STOP-NT)

Bacteremia | Endocarditis | Acute Bacterial Skin and Skin Structure Infections | Health Care Associated Pneumonia | Osteomyelitis/Septic Arthritis

United States
West China Hospital

Completed

Real-world Daptomycin Use in Chinese ICUs

Intensive Care Unit | Daptomycin | Real-world Study

China
Merck Sharp & Dohme LLC

Completed

Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)

Skin Diseases, Infectious | Bacteremia | Soft Tissue Infections

Japan
Aziende Chimiche Riunite Angelini Francesco S.p.A
Hippocrates Research

Completed

Retrospective Effectiveness Study of Dalbavancin and Other Standard of Care of the Same Class in Patients With ABSSSI (REDS)

Acute Bacterial Skin and Skin Structure Infection

Greece, Italy
Methodist Health System

Enrolling by invitation

Utility Assessment of a Pharmacy-to-Dose Daptomycin

Antibiotics Causing Adverse Effects in Therapeutic Use

United States
University Hospital, Caen

Completed

Subcutaneous Daptomycin in Healthy Volunteers (DAPTOSC) (DAPTOSC)

Antibiotics | Subcutaneous Injection | Daptomycin

France
University of Maryland, Baltimore
Cubist Pharmaceuticals LLC

Completed

Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue Infections

Fasciitis, Necrotizing | Fournier's Gangrene | Severe Necrotizing Skin and Soft Tissue Infections

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Comparison of Two Bronchodilator Inhalers in Pediatric Asthmatics

Asthma

United States
M.D. Anderson Cancer Center
Cubist Pharmaceuticals LLC

Completed

Catheter Related - Gram Positive Bloodstream Infections

Bloodstream Infection

United States
Cubist Pharmaceuticals LLC

Terminated

Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)

Infective Endocarditis

United States
Zhongnan Hospital

Unknown

A Pharmacokinetics Study of Daptomycin in Critically Ill Patients and Effects of Daptomycin on Kidney

Infection | Outcome, Fatal

China
Hospices Civils de Lyon

Unknown

Description of Eosinophilic Pneumonia in BJI/PJI Treated by Daptomycin

Bone and Joint Infection | Dactinomycin Adverse Reaction

France
McGill University Health Centre/Research Institute...

Completed

Daptomycin as Adjunctive Therapy for Staphylococcus Aureus Bacteremia (DASH)

Bacteremia | Methicillin Susceptible Staphylococcus Aureus Septicemia

Canada
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Unknown

The Efficacy and Safety of Daptomycin in the Treatment of Gram-positive Bacterial Infection.

Antibiotic

China
Heinrich-Heine University, Duesseldorf
German Research Foundation

Completed

Staphylococcus Aureus Bacteremia Antibiotic Treatment Options (SABATO)

Staphylococcus Aureus Infection

France, Germany, Netherlands, Spain, United Kingdom
Cubist Pharmaceuticals LLC

Completed

Study of Single Dose Daptomycin in Pediatric Patients With Gram-positive Infection for Which They Are Receiving Standard Antibiotics

Gram-positive Bacterial Infections

United States
CAMC Health System

Completed

Vancomycin and Daptomycin Plus Cefazolin for Preoperative Vascular Surgery Prophylaxis

MRSA Infections

United States
Cumberland Pharmaceuticals

Terminated

A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial

Bacteremia

United States
Cubist Pharmaceuticals LLC

Completed

Comparative Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia

Pneumonia, Bacterial
Cubist Pharmaceuticals LLC

Completed

Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia Due to S. Pneumoniae

Pneumonia, Bacterial
Cubist Pharmaceuticals LLC

Completed

PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections

Gram Positive Infection | Concurrent Antibiotic Treatment

United States
Cubist Pharmaceuticals LLC

Completed

Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibiotics

Gram Positive Bacterial Infection

United States
University Hospital, Montpellier

Completed

Retrospective Analysis of Nephrotoxicity During Daptomycin Versus Vancomycin Treatments in High Risk Patients (DVN)

Surgical Site Infection | Infective Endocarditis | Mediastinitis | Infection Related to Ventricular Assist Device | Infection Related to Vascular Prothesis

France
University Hospital Tuebingen

Completed

Daptomycin Concentration in Drainage Fluid and Blood Samples of ICU Patients

Heart Assist Device

Germany
Arrevus Inc.

Terminated

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

Prosthetic Joint Infections of Hip | Prosthetic Joint Infections of Knee | Infected Spacers

United States
Cubist Pharmaceuticals LLC

Terminated

Study Comparing Cubicin With Vancomycin in Treatment of Participants With Complicated Skin and Skin Structure Infections in a Home Infusion Setting

Complicated Skin or Skin Structure Infection

United States
Cubist Pharmaceuticals LLC

Terminated

Phase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA Bacteremia (HDSAB)

Infective Endocarditis | Endocarditis, Bacterial

United States
University Hospital Inselspital, Berne

Terminated

Daptomycin in Pediatric Patients With Bacterial Meningitis

Meningitis

Switzerland
Cellceutix Corporation

Completed

Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections

Bacterial Infection | Skin Infection

United States
Cubist Pharmaceuticals LLC

Completed

Safety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Structure Infections

Skin Diseases, Infectious

United States, India, Panama
Cubist Pharmaceuticals LLC

Completed

Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA (DAPHEOR1006)

Staphylococcal Skin Infections

United States, Puerto Rico
Cubist Pharmaceuticals LLC

Terminated

Study of Daptomycin Safety and Efficacy for Complicated Skin and Skin Structure Infections (cSSSI) and Bacteremia in Renal Impairment (RENSE)

Renal Impairment | Complicated Skin and Skin Structure Infections | S. Aureus Bacteremia

United States
Cubist Pharmaceuticals LLC

Completed

Safety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus Bacteremia (MK-3009-005)

Bacteremia
Cubist Pharmaceuticals LLC

Completed

Safety and Efficacy Study of Daptomycin Compared to Active Comparator in Pediatric Participants With Acute Hematogenous Osteomyelitis (AHO) (MK-3009-006)

Acute Hematogenous Osteomyelitis
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

Daptomycin or Vancomycin in Treating Bacteria in the Blood in Patients With Neutropenia Caused By Chemotherapy

Unspecified Childhood Solid Tumor, Protocol Specific | Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Infection

United States

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