Search clinical trials for: delta opioid receptor agonist

Total 34911 results

Beijing Friendship Hospital

Recruiting

Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy

Postoperative Vomiting | Laparoscopic Sleeve Gastrectomy | Postoperative Recovery | Opioid-Free Anesthesia

China
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
matthieu clanet

Completed

Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass

Analgesics, Opioid

Belgium
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal (RELEASE)

Opioid Withdrawal

United States
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Cubist Pharmaceuticals LLC
Pfizer

Completed

Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Cubist Pharmaceuticals LLC
Pfizer

Terminated

Study to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Participants With Postherpetic Neuralgia

Postherpetic Neuralgia

United States
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
University of Ioannina

Recruiting

Opioid-free Anaesthesia in Breast Cancer Surgery

Pain, Postoperative | Breast Cancer | Anesthesia | Pain, Chronic | Cancer Recurrence | Opioid Free Anaesthesia

Greece
Aswan University

Recruiting

Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects

Dexmedetomidine | Fentanyl

Egypt
Indonesia University

Not yet recruiting

Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery

Anesthesia and Analgesia | Anesthesia, Endotracheal
Johns Hopkins University
National Institutes of Health (NIH)

Not yet recruiting

Behavioral Pharmacology of Orally Administered THC and D-limonene

THC | Subjective Drug Effects | D-limonene

United States
Tribhuvan University Teaching Hospital, Institute...

Not yet recruiting

Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia

Visceral Pain
Ain Shams University

Not yet recruiting

Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia

Pain, Postoperative | Quality of Recovery | Elective Laparoscopic Cholecystectomy

Egypt
Boston Children's Hospital

Recruiting

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Pain | Emergence Delirium | Anesthesia | Tonsillitis | Opioid Analgesic Adverse Reaction | Post-operative Nausea and Vomiting (PONV)

United States
Ain Shams University

Not yet recruiting

Dexmedetomidine in Spinal Anesthesia Decreasing Post Spinal Shivering in Caesarean Section

Post Spinal Shivering
Iuliu Hatieganu University of Medicine and Pharmacy

Not yet recruiting

Dexmedetomidine vs. Remifentanil Conscious Sedation for Stapedotomy/Stapedectomy

Otosclerosis

Romania
Al-Azhar University
Benha University

Recruiting

Adding Dexmedetomidine or Tramadol to Paracetamol- An Effort to Attenuate Catheter Related Bladder Discomfort

Percutaneous Nephrolithotripsy (PCNL)

Egypt
Aydin Adnan Menderes University

Recruiting

Erector Spinae Block -Dexmedetomidine (esp -dex)

Opioid Consumption | Postoperative Acute Pain

Turkey
Yale University
University of Pennsylvania

Recruiting

Vitamin D in OUD: Exploration of Alterations on the Dopamine D2/D3 Receptor System

Opioid Use Disorder

United States
Hassan II University

Not yet recruiting

Continuous Infusion of Norepinephrine vs Phenylephrine During Spinal Anesthesia for Cesarean Section (INPEACE) (INPEACE)

Cesarean Section Complications | Hypotension

Morocco
University of Wisconsin, Madison

Not yet recruiting

High Confusion: Cannabis & Driving

Impairment, Cognitive | Impairment of Attention | Impairment, Psychomotor
Wayne State University

Not yet recruiting

Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery (CAPER)

PTSD | Post Traumatic Stress Disorder

United States
Johns Hopkins University
Substance Abuse and Mental Health Services Administration (SAMHSA)

Not yet recruiting

Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance

Cannabis

United States
Ain Shams University

Recruiting

Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring

Sevoflurane | Dexmedetomidine | Spine Surgery | Propofol | Fentanyl | Motor Evoked Potential | Somatosensory Evoked Potential

Egypt
Siriraj Hospital

Recruiting

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Critical Illness | Respiratory Failure | Lung Injury | Respiratory Distress Syndrome, Adult | Mechanical Ventilation Complication

Thailand
DR. DIANE CHISESI NFS. MD. PHD.
IRB

Not yet recruiting

Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant Joint Tumor (NASBP-B-09)

Chronic Pain | Metastatic Breast Cancer | Tumor | Muscle Neoplasms

United States
Saglik Bilimleri Universitesi Gazi Yasargil Training...

Not yet recruiting

Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study (Effects of Dex)

Rhinoplasty Surgery
Universidad Simón Bolívar

Not yet recruiting

Intraoperative Autonomic Neural Blockade (ANB)

Pain, Postoperative | Analgesia | Opioid Use | Nausea, Postoperative | Vomiting, Postoperative
Cedars-Sinai Medical Center

Not yet recruiting

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

Dexmedetomidine | Adolescent Idiopathic Scoliosis | Remifentanil | Posterior Spinal Fusion | Multimodal Analgesia | Opioid Induced Hyperalgesia
Centre Hospitalier Universitaire de Nīmes

Recruiting

Evaluation of the Hemodynamic Effect of Dexmedetomidine in Scheduled Outpatient Surgery (DEXCOEUR)

Anesthesia | Dexmedetomidine | Hemodynamics | Ambulatory Care

France
Assiut University

Not yet recruiting

Prevention of Shivering Associated With Spinal Anesthesia

Shivering, Spinal Anesthesia
Assiut University

Not yet recruiting

Intrathecal Dexmedetomidine Versus Intrathecal Morphine Inpatients Undergoing Cardiac Valve Replacement Surgeries

Cardiac Valve Disease
Yale University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Genetics of Cannabis Use Disorder and Cannabinoid Response in Humans

Schizophrenia | Cannabis Use Disorder

United States
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetic and Safety Study of Oral Lofexidine in Neonates Experiencing Opioid Withdrawal Due to Intrauterine Exposure to Opioids

Opioid Withdrawal (Disorder)

United States
Stanford University

Not yet recruiting

CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial

Back Pain | Chronic Pain | Neck Pain | Opioid Misuse
Ain Shams University

Recruiting

Single Shot Intrathecal Analgesia in Vaginal Delivery

Effectiveness of Single Shot Intra-thecal Analgesia in Multiparous Women Scheduled for Normal Vaginal Delivery

Egypt
Peking University First Hospital

Recruiting

Dexmedetomidine-esketamine for Percutaneous Radiofrequency Liver Ablation

Dexmedetomidine | Liver Cancer | Radiofrequency Ablation | Esketamine

China
University of Pennsylvania

Recruiting

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal (UH3)

Opioid Use | Opiate Withdrawal Syndrome

United States
Yale University
National Institute on Drug Abuse (NIDA); VA Connecticut Healthcare System

Recruiting

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

Pain, Tolerance | Oral vs Vaporized THC | Abuse Liability

United States
Fudan University

Recruiting

Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01)

Breast Cancer

China
Salem Anaesthesia Pain Clinic

Recruiting

Kratom Use Disorder Management Using Clonidine and/or Buprenorphine

Withdrawal Syndrome

Canada
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Age-dependent Effects of Smoked and Oral Delta-9-THC (SAGE)

Pain | Abuse, Drug | Intoxication; Cannabinoids
Yonsei University

Recruiting

Comparison of Patients' Satisfaction Between Dexmedetomidine and Remimazolam Anesthesia in Patients With Atrial Fibrillation Undergoing Catheter Ablation

Patients With Atrial Fibrillation Undergoing Catheter Ablation

Korea, Republic of
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Clinical Study on the Effect of Tizanidine on the Function and Pain of Patients After Shoulder Arthroscopy

Rotator Cuff Tears
Dr Kassiani Theodoraki
Sotiria General Hospital

Not yet recruiting

Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surgeries

Pain, Postoperative | Analgesia | Pain, Acute | Dexmedetomidine | Pain, Chronic | Morphine

Greece
University Hospital "Sestre Milosrdnice"

Not yet recruiting

Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery

Postoperative Pain | Cesarean Section | Wound Heal
Loyola University

Recruiting

Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

Pain, Postoperative

United States
Indiana University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-Drug Interaction

United States

Search clinical trials for: delta opioid receptor agonist

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Macedonia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations