Search clinical trials for: dose dense chemotherapy

Total 32009 results

Ottawa Hospital Research Institute

Recruiting

Evaluating Omission of Granulocyte Colony-stimulating Factors in Breast Cancer Patients Receiving Paclitaxel Portion of Dose-dense Adriamycin-cyclophosphamide and Paclitaxel Chemotherapy (REaCT-OGF)

Early-stage Breast Cancer

Canada
Shantou Central Hospital

Recruiting

Neoadjuvant Dose-dense Chemotherapy for HR+/HER2- Breast Cancer Patients With High Proliferation Index

Breast Cancer

China
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Validation of a Treatment Algorithm for Poor-Risk NSGCTnon Seminomatous Germ-cell Tumors (VAPOR)

Non-Seminomatous Germ Cell Tumor

France
Peking University
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Effectiveness of Cryotherapy Combined With Compression Therapy for Preventing Chemotherapy-induced Peripheral Neuropathy

Breast Cancer

China
Centre Georges Francois Leclerc

Recruiting

Evaluation and Modeling of the Effect of G-CSF on the Evolution of Polynuclear Neutrophils During Dense Dose Epirubicin-Cyclophosphamide Regeneration (EMEG-ECDD)

Localized Breast Cancer

France
Georgetown University

Recruiting

RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer (RAGE)

Non-metastatic Breast Cancer | Cancer Related Cognitive Decline

United States
Second Affiliated Hospital, School of Medicine,...
Women's Hospital School Of Medicine Zhejiang University; Zhejiang Provincial... and other collaborators

Recruiting

Efficacy and Safety of Dose-dense Chemotherapy (ddEC-ddP) for Neoadjuvant Chemotherapy of HER2-negative Breast Cancer

HER2-negative Breast Cancer | Neoadjuvant Chemotherapy

China
Fudan University

Recruiting

Carboplatin Intensified Chemotherapy for TRIple NEgative Breast Cancer(CITRINE) (CITRINE)

Triple-negative Breast Cancer

China
Pusan National University Yangsan Hospital

Recruiting

Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma

Urothelial Carcinoma | Neoadjuvant Chemotherapy | Muscle Invasive Bladder Cancer

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...

Recruiting

The Trial Comparing Dose-dense AC-T With TP as Adjuvant Therapy for TNBC With Homologous Recombination Repair Deficiency

Triple Negative Breast Cancer

China
Tianjin Medical University Cancer Institute and...

Recruiting

Evaluation of the Relationship of TOP2α Expression and Effect of Non Dose-dense Chemotherapy for Breast Cancer

Breast Cancer

China
Charite University, Berlin, Germany

Not yet recruiting

NeoAdjuvant Chemotherapy Followed by Radical Hysterectomy (OP) Versus Primary Chemo-RADiation in Cervical Cancer FIGO Stage IB2 and IIB (NACOPRAD)

Cervical Cancer
G1 Therapeutics, Inc.

Completed

Trilaciclib, a CDK4/6 Inhibitor, in Patients With Early-Stage Triple Negative Breast Cancer

Breast Cancer | Triple Negative Breast Cancer

United States
University Hospital, Saarland

Completed

Dose Dense Chemotherapy in Elderly Patients > 80 Years Old With DLBCL

DLBCL | Old Age; Debility

Germany
Hoffmann-La Roche
Breast International Group; Frontier Science & Technology Research Foundation... and other collaborators

Completed

A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone In Patients With Operable Triple-Negative Breast Cancer (IMpassion030)

Triple Negative Breast Cancer

Russian Federation, United States, Israel, Italy, Spain, France, Korea, Republic of, United Kingdom, Denmark, Taiwan, Hungary, Argentina, Australia, Austria, Belgium, Brazil, China, Germany, Hong Kong, Japan, Mexico, Romania, Switze... and more
Icahn School of Medicine at Mount Sinai

Terminated

Neoadjuvant Dose-Dense For Early Her2Neu Positive Breast Cancer

Locally Advanced Breast Cancer

United States
Case Comprehensive Cancer Center

Terminated

Weight-based Dosing for Dense Weekly Paclitaxel and Carboplatin in Overweight Patients w/ Body Surface Area (BSA) > 2.0

Gynecologic Malignancies

United States
The Netherlands Cancer Institute

Terminated

Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD

Breast Cancer

Netherlands
Far Eastern Memorial Hospital

Completed

Dose-dense Chemotherapy Versus Intraperitoneal Chemotherapy as First-line Chemotherapy in Advanced Ovarian Cancer

Advanced Ovarian Cancer

Taiwan
Sidney Kimmel Comprehensive Cancer Center at Johns...
Breast Cancer Research Foundation

Completed

Trial of Partial Breast Irradiation With Various Concurrent Chemotherapy Regimens (PBIC)

Breast Cancer

United States
Centre Hospitalier Universitaire de Besancon

Terminated

Preoperative Dose-dense Chemotherapy With Weekly Cisplatin, Epirubicin and Paclitaxel to Treat Patients With Locally Gastric Cancer (IPEC-GC)

Stomach Neoplasms | Oesophageal Junction Cancer | Lower Oesophagus Cancer

France
Yonsei University

Completed

Safety and Efficacy of Pegteograstim in Korean Breast Cancer Patients

Breast Cancer

Korea, Republic of
Agendia
University of South Florida; University of Miami; University of Oklahoma; Ohio... and other collaborators

Completed

MINT I Multi- Institutional Neo-adjuvant Therapy MammaPrint Project I (MINT)

Breast Cancer

United States
Beaumont Hospital

Completed

Dose Dense Chemotherapy With Lipegfilgrastim Support in Early Breast Cancer

Breast Cancer

Ireland
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Six vs 12 Months of Trastuzumab With Docetaxel Following FEC as Adjuvant Treatment in N+ Breast Cancer

Breast Cancer

Greece
Universitaire Ziekenhuizen KU Leuven
St-Augustinus Wilrijk

Completed

Trial Exploring Feasibility of Densification and Optimal Sequencing of Postoperative Adjuvant Fluorouracil, Epirubicin Plus Cyclophosphamide (FEC) and Docetaxel Chemotherapy in Patients With High Risk Primary Operable Breast Cancer

Breast Cancer

Belgium
Nordic Lymphoma Group
Amgen

Completed

Dose Dense Chemotherapy and Rituximab for Young High Risk Diffuse Large B-Cell Lymphoma Patients (CRY-04) (CRY-04)

Diffuse Large B-Cell Lymphoma

Norway, Denmark, Finland, Sweden
Duke University
Sanofi

Terminated

Dose-Dense Induction/Neoadjuvant Chemotherapy in Locally Advanced Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

United States
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Sequential Administration of FE75C and Docetaxel Versus Docetaxel/Cyclophosphamide in HER-2 Negative, Node Positive Breast Cancer

Breast Cancer

Greece
Harold J. Burstein, MD, PhD
Massachusetts General Hospital; Beth Israel Deaconess Medical Center; Celgene...

Completed

Dose Dense Abraxane in Adjuvant Chemotherapy for Breast Cancer

Breast Cancer

United States
University of Göttingen
Nordic Lymphoma Group; German High-Grade Non-Hodgkin's Lymphoma Study Group

Unknown

Immunotherapy in Peripheral T Cell Lymphoma - the Role of Alemtuzumab in Addition to Dose Dense CHOP (A-CHOP-14)

Extranodal NK/T-cell Lymphoma | Peripheral T Cell Lymphoma, Unspecified | Angioimmunoblastic Lymphadenopathy

Germany
Central European Cooperative Oncology Group

Terminated

Phase II Trial of Dose-dense Paclitaxel and Cisplatin as Neo-adjuvant Chemotherapy for Operable Stage II and IIA NSCLC

Non-Small Cell Lung Cancer

Austria, Hungary, Poland
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Paclitaxel and Carboplatin Combination as 1st Line Treatment in Ovarian Carcinomas

Ovarian Cancer

Greece
Fondazione Italiana Linfomi ONLUS
Centro di Riferimento per l'Epidemiologia e la Prev. Oncologica Piemonte

Unknown

Dose Dense Chemotherapy + Rituximab +/-Intensified High Dose Chemoimmunotherapy With Support of Peripheral Autologous Stem Cell in Diffuse Large B-Cell Lymphoma (DLCL04)

Diffuse Large B-Cell Lymphoma | IPI≥2

Italy
Amgen

Completed

ACCELERATE: Doxorubicin and Cyclophosphamide Followed by Paclitaxel With Pegfilgrastim and Darbepoetin Alfa Support for the Treatment of Women With Breast Cancer

Breast Cancer
Hellenic Oncology Research Group
University Hospital of Crete

Completed

Randomized Phase III Trial Comparing Sequential Administration of FE75C Followed by Docetaxel Versus Paclitaxel as Adjuvant Chemotherapy in Axillary Lymph Node (+) Breast Cancer

Breast Cancer

Greece
Chap, Linnea I., M.D.
Genentech, Inc.

Unknown

Dose-Dense Chemotherapy Plus Bevacizumab in High Risk Lymph Node Positive Breast Cancer: A Pilot Study

Breast Cancer

United States
Arbeitsgemeinschaft medikamentoese Tumortherapie

No longer available

Dose-Dense Therapy in Aggressive Lymphoma

Lymphoma
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
KARANAHAN

Recruiting

Clinical Study of Personalized Chemotherapy for Breast Cancer With Low Doses of Cyclophosphamide

Stage IV Breast Cancer

Russian Federation
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Northside Hospital, Inc.

Not yet recruiting

Adding Venetoclax to the High-dose Chemotherapy Regimen Prior to Mismatche Allogeneic Stem Cell Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Sun Yat-sen University

Not yet recruiting

SBRT and LDRT Combined With PD-1 Antibody and Chemotherapy in r/m Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Baylor College of Medicine
NeuroMetrix, Inc.

Recruiting

Transcutaneous Electrical Nerve Stimulation (TENS) for Chemotherapy Induced Peripheral Neuropathy (CIPN)

Pain | Neuropathy | Chemotherapy-induced Peripheral Neuropathy

United States
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Leiden University Medical Center
Dutch Colorectal Cancer Group; Stichting Darmkanker

Not yet recruiting

DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients With Metastatic Colorectal Cancer (DOSAGE)

Colorectal Cancer | Metastatic Cancer | Older Patients | Candidates for Palliative Chemotherapy

Netherlands
First Affiliated Hospital of Wenzhou Medical University

Not yet recruiting

Tislelizumab Plus Chemotherapy as Postoperative Adjuvant Therapy in Elderly Patients With LA GC/GEJC

Gastric Cancer
AbbVie

Recruiting

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (LIVIGNO-4)

Non-Small Cell Lung Cancer

United States, Israel, Japan
Sichuan University

Not yet recruiting

Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC

Lung Cancer | Extensive-stage Small-cell Lung Cancer

China
Carmel Medical Center

Recruiting

POST URS Chemotherapy Instillation

UTUC

Israel

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