Search clinical trials for: drug discontinuation

Total 258156 results

UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya

Cervix Cancer | Cervix Intraepithelial Neoplasia Grade 3 | Cervix; Intraepithelial Neoplasia, Grade I | Cervix; Intraepithelial Neoplasia, Grade II

Kenya
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Discontinuation of CDK4/6 Inhibitors in Patients With Metastatic HR Positive, HER2 Negative Breast Cancer

Breast Cancer

Germany
Massachusetts General Hospital
Foundation Medicine

Recruiting

Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation

Melanoma | Non-small Cell Lung Cancer

United States
Center of target therapy

Recruiting

Incidence of Viral Hepatitis D Relapses Upon Discontinuation of Bulevirtide in Patients With Chronic Hepatitis D and Negative HDV RNA

Chronic Hepatitis D

Russian Federation
Johns Hopkins University
Doris Duke Charitable Foundation

Recruiting

Dupilumab De-escalation in Pediatric Atopic Dermatitis

Atopic Dermatitis

United States
FANG HE

Recruiting

Aspirin Discontinuation in High-Risk Pregnant Women of Preeclampsia

Preeclampsia | Perinatal Haemorrhage

China
St. Olavs Hospital

Recruiting

Screening for Preeclampsia in Norway With Aspirin Discontinuation at 24-28 Weeks (PEScreenNor)

Pre-Eclampsia

Norway
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
Qilu Hospital of Shandong University

Not yet recruiting

Clinical Observation of Long-term Cardiac Function Prognosis in Patients With PPCM Who Have Recovered Cardiac Function

Cardiomyopathy, Dilated
Centre Hospitalier Universitaire Dijon

Not yet recruiting

TocilizuMab discontinuAtion in GIant Cell Arteritis (MAGICA)

Giant Cell Arteritis

France
University Hospital Birmingham

Recruiting

The Effects of Growth Hormone Treatment Discontinuation in Adults on Metabolic Profile, Body Composition and Quality Of Life (GAMBOL Study) (GAMBOL)

Adult Growth Hormone Deficiency

United Kingdom
Rigshospitalet, Denmark

Recruiting

Cardiac Implantable Electronic Device Lifelong Antibiotic thErapy vs Stop and See (CIEDLESS)

Cardiac Implantable Electronic Device Infection

Denmark
Fundaleu

Recruiting

Study of Treatment Free Remission in Patients With Chronic Myeloid Leukemia in Chronic Phase (AST)

CML

Argentina
4th Military Clinical Hospital with Polyclinic,...

Recruiting

Comparison of the Efficacy and Safety of Cardioneuroablation to Permanent Pacing in Patients With an Implanted Pacemaker for Symptomatic Bradycardia. (GENTLE-PACE)

Bradycardia | Syncope

Poland
University of Sao Paulo General Hospital
GlaxoSmithKline

Recruiting

Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases (RZVRheum)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Juvenile Idiopathic Arthritis | Sjogren's Syndrome | Spondylitis, Ankylosing | Spondyloarthritis | Behçet Disease | Idiopathic Inflammatory Myopathies | Vasculitis, Systemic | Dermatomyositis, Juvenile

Brazil
University College Cork
Cancer Research@UCC

Recruiting

Discontinuation Study

Cancer | Multiple Myeloma | Hematologic Cancer

Ireland
University Health Network, Toronto

Not yet recruiting

Short Antibiotic Treatment in High Risk Febrile Neutropenia

Febrile Neutropenia
Poitiers University Hospital

Recruiting

Discontinuation of TyrosIne Kinase Inhibitors (TKI) in Chronic Myeloid Leukemia (CML) and Impact on the Immune System

Chronic Myeloid Leukemia | Tyrosine Kinase Inhibitors

France
Shanghai Mental Health Center
Merck Sharp & Dohme LLC

Recruiting

Predictors of Functional Remission in Discharged Patients With Schizophrenia After Long-term Drug Discontinuation

Schizophrenia

China
Hospices Civils de Lyon

Not yet recruiting

Effectiveness of CFTR Modulators According to Co-therapy (MODUCO)

Cystic Fibrosis
Dong-A ST Co., Ltd.

Recruiting

Efficacy and Safety of Actonel® After Denosumab Discontinuation in Postmenopausal Osteoporosis Women

Postmenopausal Osteoporosis

Korea, Republic of
Insel Gruppe AG, University Hospital Bern
University of Bern

Recruiting

STREAM Trial - Biomarker (STREAM-Bio)

Statin Treatment for Primary Prevention

Switzerland
Insel Gruppe AG, University Hospital Bern
University of Bern

Recruiting

STREAM Trial - Subclinical Atherosclerosis (STREAM-SubATS)

Statin Treatment for Primary Prevention

Switzerland
Assistance Publique - Hôpitaux de Paris

Recruiting

Early Discontinuation of Steroid Treatment in Negative FDG-PET/CT Patients With Idiopathic Retroperitoneal Fibrosis (METRO)

Idiopathic Retroperitoneal Fibrosis

France
University of British Columbia
Centre for Addiction and Mental Health; Canadian Institutes of Health Research... and other collaborators

Recruiting

Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study

Major Depressive Disorder, Recurrent, in Remission

Canada
University of Calgary

Recruiting

Efficacy of Zoledronic Acid to Prevent Bone Loss Following Denosumab Discontinuation

Osteoporosis | Bone Loss | Osteopenia | Osteoporosis, Postmenopausal

Canada
University Hospital, Toulouse

Recruiting

Impact of Procalcitonin-guided Algorithm on Early Discontinuation of Antibiotic Therapy (PRODISCO)

Bacterial Infections

France
Göteborg University
Sahlgrenska University Hospital, Sweden

Not yet recruiting

Discontinuation of Antiviral Therapy as a Strategy to Cure Hepatitis B (STOP-B)

Hepatitis B, Chronic

Sweden
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; Rho Federal Systems Division, Inc.; Autoimmunity Centers of...

Recruiting

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis (AMS05)

Multiple Sclerosis

United States
Spanish Breast Cancer Research Group
Pierre Fabre Laboratories; Puma Biotechnology, Inc.

Recruiting

Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib (DIANER)

HER2 Positive Breast Cancer | Hormone Receptor Positive | Early-stage Breast Cancer

Spain
Universitätsklinikum Hamburg-Eppendorf
University Hospital, Essen; Philipps University Marburg Medical Center; Helmut...

Recruiting

Disentangling Pharmacological and Expectation Effects in Antidepressant Discontinuation (PHEA)

Depressive Symptoms | Expectations | Antidepressants

Germany
University Hospital Inselspital, Berne
University of Bern

Recruiting

STREAM Trial - Statins in Multimorbid Older Adults Without Cardiovascular Disease (STREAM)

Statin Treatment for Primary Prevention

Switzerland
UConn Health

Recruiting

Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction (HFpEF-BB)

Heart Failure With Preserved Ejection Fraction

United States
Dan Liang

Recruiting

Reduction or Discontinuation of TNF-α Inhibitor in Non-infectious Uveitis Patients

Uveitis | Adalimumab

China
Atsushi Kawakami
AbbVie GK.

Recruiting

Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate (DOPPLER)

Rheumatoid Arthritis | Biomarker | JAK Inhibitor | Musculoskeletal Ultrasound

Japan
Medical University of Vienna
Medical University of Graz; Medical University Innsbruck; Hospital Hietzing; Krankenhaus...

Not yet recruiting

Screening for Flare After b/tsDMARD Discontinuation in Rheumatoid Arthritis

Rheumatoid Arthritis
RenJi Hospital

Recruiting

The Role of Neuromodulators in Refractory Functional Dyspepsia

Dyspepsia | Functional Gastrointestinal Disorders | Antidepressant Drug Adverse Reaction | Antidepressant Discontinuation Syndrome

China
Emory University
National Institute of Mental Health (NIMH)

Recruiting

Parrying the Pitfalls of PrEP: Project PEACH

HIV | STI

United States
Universitätsklinikum Hamburg-Eppendorf
University Hospital, Essen; Philipps University Marburg Medical Center; Helmut...

Recruiting

Combined N-of-1 Trials to Assess Open-Label Placebo Treatment for Antidepressant Discontinuation Symptoms (FAB)

Depressive Symptoms | Expectations | Antidepressants

Germany
Philip Kern
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics

Obesity | Pre-diabetes

United States
ANRS, Emerging Infectious Diseases
EUCLID Clinical Trial Platform

Recruiting

ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation (IP-CURE-B)

Hepatitis B, Chronic

France, Germany, Italy, Spain
DemeRx IB, Inc.
Hammersmith Medicines Research; ERT: Clinical Trial Technology Solutions; MAC...

Recruiting

A Study of Oral Ibogaine in Opioid Withdrawal

Opiate Withdrawal Syndrome

United Kingdom
Sheba Medical Center
Rambam Health Care Campus; AstraZeneca; Tel-Aviv Sourasky Medical Center

Recruiting

Concomitant Radiotherapy, Tremelimumab & Durvalumab for Advanced NSCLC Patients Progressing on First-line Immunotherapy (CORAL-Lung)

Metastatic or Locally Advanced NSCLC

Israel
Samuel Silver
Unity Health Toronto

Recruiting

Promoting Kidney Recovery After Acute Kidney Injury Receiving Dialysis (Recover-AKI)

Acute Kidney Injury

Canada
Radboud University Medical Center
Dutch Society of Physicians for Pulmonology and Tuberculosis

Recruiting

Dose Tapering and Early Discontinuation to InCreAse cosT-effectIveness Of Immunotherapy for NSCLC (DEDICATION-1)

NSCLC

Netherlands
Medical College of Wisconsin
H. Jean Khoury Cure CML Consortium

Recruiting

Protocol Number: HJKC3-0003. Treatment Free Remission After Combination Therapy With Asciminib (ABL001) Plus Tyrosine Kinase Inhibitors (TKI) in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Chronic Phase Chronic Myelogenous Leukemia

United States
University of Colorado, Denver

Recruiting

Premature Discontinuation of Contraceptive Implants

Contraception Behavior

United States
Hospices Civils de Lyon

Recruiting

STRESS From in Charge Relative Facing the Announcement of Decisions Limiting or Stopping Treatments in Emergency Room During the COVID-19 Epidemic (COVER ACC)

Covid19 | Anxiety | Post Traumatic Stress Disorder

France
Samsung Medical Center
Chonbuk National University Hospital; Chonnam National University Hospital; Korea... and other collaborators

Recruiting

Long-term Beta-blocker Therapy After Acute Myocardial Infarction (SMART-DECISION)

Myocardial Infarction

Korea, Republic of
University of Milano Bicocca

Recruiting

Retro-prospective Observational Study on Risk of Progression in CP-CML Patients Eligible for TKI Discontinuation

Chronic Myeloid Leukemia

Italy, Canada, Germany, Spain

Search clinical trials for: drug discontinuation

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