Search clinical trials for: first in human

Total 454988 results

Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
Shanghai Unicar-Therapy Bio-medicine Technology...
Peking University People's Hospital; The First Affiliated Hospital of Soochow...

Not yet recruiting

Clinical Trial of ssCART-19 Cell Injection in the Treatment of Relapsed or Refractory Acute Lymphoblastic Leukemia (Including Central Nervous System Infiltration)

Relapsed or Refractory Acute Lymphoblastic Leukemia

China
Obstetrics & Gynecology Hospital of Fudan University
Peking Union Medical College Hospital; First Affiliated Hospital of Xinjiang... and other collaborators

Not yet recruiting

Role of Methylation Test Triage in HPV Positive Women (MTTRIHPW)

Precancerous Cervical Lesion

China
Versa Vascular, Inc

Not yet recruiting

A First in Human Study for the Versa Device for Tricuspid Regurgitation

Tricuspid Regurgitation

New Zealand
First Affiliated Hospital of Wenzhou Medical University

Recruiting

Efficacy and Safety of Antiviral Therapy With Peg-interferon for Chronic Hepatitis B Complicated With Nonalcoholic Fatty Liver Disease（OCEAN PROJECT）

Chronic Hepatitis b | Nonalcoholic Fatty Liver Disease

China
Changchun BCHT Biotechnology Co.
The First Affiliated Hospital of Yunnan University of Traditional Chinese... and other collaborators

Not yet recruiting

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of the Fully Human Anti-tetanus Toxin Monoclonal Antibody A82 / B86 Injection Combination Formulation

Clostridium Tetanus
AdjuTec Pharma AS
CTC Clinical Trial Consultants AB

Not yet recruiting

A First-in-human Trial to Evaluate Safety, Tolerability, and Pharmacokinetics of APC148 in Healthy Adults

Healthy Subjects

Sweden
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Bayer

Not yet recruiting

A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer

Hepatocellular Carcinoma (HCC)

United States
Hyalex Orthopaedics, Inc.

Recruiting

The Hyalex First-in-Human Study

Cartilage Injury

Poland
NeuShen Therapeutics

Not yet recruiting

First-into-human Study of NS-136 in Healthy Subjects

Healthy Subjects

Australia
Synergia Medical

Not yet recruiting

A First in hUman Study for Resistant Epilepsy With the Vagus Nerve stimulatiOn Device by syneRgia medicAl (AURORA)

Drug Resistant Epilepsy
University of California, Los Angeles

Recruiting

Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

Bladder Cancer | Kidney Failure | Bladder, Neurogenic | Bladder Disease

United States
Chang Gung Memorial Hospital
DOTSPACE

Recruiting

First-In-Human Study of PDT to Detect IAH

Intra-Abdominal Hypertension

Taiwan
Ascentage Pharma Group Inc.

Recruiting

A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.

CLL/SLL

China
Bio-Thera Solutions

Recruiting

BAT1308 in Combination With Platinum-containing Chemotherapy is Used for the First-line Treatment of Advanced or Recurrent dMMR Endometrial Cancer

Endometrial Cancer

China
Sinocelltech Ltd.

Not yet recruiting

A First-in-human Study of SCTB35 in Patients With Relapse/Refractory B-cell Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, B-cell

China
Children's Hospital of Soochow University

Recruiting

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

AML, Childhood | C-KIT Mutation | Refractory AML | Relapse/Recurrence | Core Binding Factor Acute Myeloid Leukemia

China
UMC Utrecht
Health Holland; Dutch Kidney Foundation; Servicio Madrileno De Salud (SERMAS); European... and other collaborators

Recruiting

First-in-human Study to Examine Safety of a New Peritoneal Dialysis Device (WEAKID) in End-stage Kidney Disease Patients (CORDIAL)

Chronic Kidney Diseases | Renal Insufficiency, Chronic | Kidney Failure, Chronic

Netherlands, Italy, Spain
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
Nanjing First Hospital, Nanjing Medical University

Recruiting

Endostar Combined With SBRT and Envafolimab in the Treatment of Advanced Gastrointestinal Tumors

Gastrointestinal Neoplasms

China
Eli Lilly and Company

Not yet recruiting

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

Alzheimer Disease

United States, United Kingdom, Japan
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Not yet recruiting

A Clinical Study of Recombinant Human Coagulation Factor VIII for Injection in Patients With Severe Hemophilia A

Hemophilia A

China
Bayer

Recruiting

A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants

Healthy Volunteers | Heartburn | Indigestion | Stomach Acid Related Symptoms | Nocturnal Stomach Acid Related Symptoms

United Kingdom
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
3H (Suzhou) Pharmaceuticals Co., Ltd.

Not yet recruiting

A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations

Solid Tumors With FGFR2 Alterations, Adult

United States
Vecmedical Spain, S.L.

Recruiting

Rectal Tumor Resection Using the UNI-VEC Multichannel Transanal Access Device (UNI-VEC)

Rectal Polyp | Rectal Lesion | Sessile Colonic Polyp | Rectal Polyps | Pedunculated Colorectal Polyps

Spain
The First Affiliated Hospital of Xinxiang Medical...

Not yet recruiting

Recombinant Human Endostatin Combined With Envafolimab and Synchronal Radiochemotherapy

Locally Advanced Squamous Non-small Cell Lung Cancer
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Recruiting

Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (XT1061)

Chronic Hepatitis b

China
Chinese University of Hong Kong
Agilis Robotics Limited

Not yet recruiting

First-in-Human Trial of a Novel Endoluminal Robotic System for En-Bloc Resection of Bladder Tumours

Bladder Cancer
Latticon Antibody Therapeutics, Inc

Not yet recruiting

A First-in-Human, Phase 1/2 Study of LAT010 in Patients With Advanced Solid Tumors (LIGHTSPEED-1) (LIGHTSPEED-1)

Advanced Solid Tumor

United States
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
CytomX Therapeutics

Recruiting

First In Human Study of CX-2051 in Advanced Solid Tumors

Solid Tumor, Adult

United States
hemotune AG

Not yet recruiting

First in Human Trial to Assess the Safety & Efficacy of HemoSystem REBOOT in Patients With Sepsis-induced Immunosuppression ((RESTORE))

Septic Shock

Switzerland
BrodenBio Co., Ltd.

Recruiting

A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors

Advanced Solid Tumor

China
Eikon Therapeutics
Impact Therapeutics, Inc.

Recruiting

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
Centre Hospitalier Universitaire de Saint Etienne

Not yet recruiting

Evaluation of First-void Urine as an Alternative to Cervical Sampling for Human Papillomavirus (HPV) Testing in Cervical Cancer Screening (Single-center Study). (URAPREV)

Uterine Cervical Cancer

France
First Affiliated Hospital Bengbu Medical College

Not yet recruiting

Efficacy and Safety of Intratumoral Injection of Recombinant Human Adenovirus Type 5 Combined With Tislelizumab and Lenvatinib in the Treatment of Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma
NeuroBo Pharmaceuticals Inc.

Recruiting

First in Human Study in Subjects With Obesity, But Otherwise Healthy

Obesity

United States
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Recruiting

A Clinical Study of JS005 in Patients With Ankylosing Spondylitis

Ankylosing Spondylitis

China
Alzheimer's Disease Expert Lab (ADEL), Inc.
Oscotec Inc.

Recruiting

A Phase Ia/Ib, First-in-human (FIH) Study for Safety, Tolerability, Pharmacokinetics (PK), and Clinical Activity Evaluation of ADEL-Y01

Alzheimer Disease

United States
Bliss Biopharmaceutical (Hangzhou) Co., Ltd

Recruiting

A First-in-human of Multiplle Doses of BB-1709 in Subjects With Locally Advanced/Metastatic Solid Tumors

Solid Tumor

China
Luye Pharma Group Ltd.

Recruiting

First-in-Human Study of LPM6690176 in Patients With Advanced Solid Tumors.

Advanced Solid Tumor

China
Incyte Corporation

Recruiting

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis (TRuE-AD4)

Atopic Dermatitis

Germany, Poland, United States, Spain, United Kingdom, Italy, Belgium, Canada, Netherlands, Australia, Bulgaria, France, Switzerland, Hungary, Korea, Republic of
Per-Ola Carlsson
Sana Biotechnology

Not yet recruiting

First-in-human Safety Study of Hypoimmune Pancreatic Islet Transplantation in Adult Subjects With Type 1 Diabetes

Type1diabetes
OnKure, Inc.

Recruiting

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer (PIKture-01)

Breast Cancer | Advanced Cancer

United States
Takeda
Takeda Development Center Americas, Inc.

Not yet recruiting

A First-In-Human Study of TAK-004 in Healthy Adults

Healthy Volunteers
Genome & Company

Not yet recruiting

A First-in-human Study of GENA-104A16 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Korea, Republic of
BeiGene

Not yet recruiting

Study of BG-C9074 as Monotherapy and in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Advanced Solid Tumor
Wuhan Optics Valley Vcanbiopharma Co., Ltd.

Recruiting

Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary Fibrosis (IPF) (DEVIF-I)

Idiopathic Pulmonary Fibrosis

China

Search clinical trials for: first in human

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bangladesh

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations