Search clinical trials for: gene dose

Total 280705 results

Ohio State University
Patient-Centered Outcomes Research Institute; Northwestern University; Preeclampsia...

Not yet recruiting

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL (ASPIRIN)

Preeclampsia | Gestational Hypertension | Hypertensive Disorders of Pregnancy

United States
BioNTech SE

Not yet recruiting

A First-in-human Safety Trial of BNT331 Administered as Single Ascending Doses in Healthy Women and as Multiple Ascending Doses in Women Diagnosed With Bacterial Vaginosis

Bacterial Vaginosis

United States
Copernicus Memorial Hospital
Medical Research Agency, Poland

Not yet recruiting

Application of MET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme

Glioblastoma Multiforme

Poland
Janne Hastrup Jensen
Copenhagen University Hospital, Hvidovre

Not yet recruiting

Automated Oxygen Titration During Walking in Patients With Lung Fibrosis (OXYWILD) (OXYWILD)

Respiratory Therapy | Fibrosis Lung
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
EMD Serono Research & Development Institute, Inc.

Not yet recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

United States, Germany
Genelux Corporation
Newsoara Biopharma Co., Ltd.

Not yet recruiting

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's of Choice Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer (VIRO-25) ((VIRO-25))

Non-small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer | Advanced Non-squamous Non-small-cell Lung Cancer | Non-small Cell Lung Cancer Stage IV | Metastatic Squamous Non-Small Cell Lung Carcinoma | Non-small Cell Lung Cancer Recurrent | Metastatic Non-squamous Non Small Cell Lung Cancer and other conditions
GeneQuantum Healthcare (Suzhou) Co., Ltd.

Recruiting

A Study of GQ1010 in Subjects With Advanced Solid Tumors

Advanced Malignant Solid Tumors

China
Pfizer
AbbVie

Not yet recruiting

A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH) (CHERISH)

Gram-negative Bacterial Infection
Institute of Medical Biology, Chinese Academy of...

Not yet recruiting

Phase IV Study of Concomitant Administration of the sIPV and HepA

Hepatitis A | Polio

China
Turku University Hospital

Recruiting

Sleep Quality and Sleep-disordered Breathing in Bypass Surgery Patients (UNI-CABG)

Coronary Artery Disease | Sleep Disorder

Finland
Technical University of Munich
Universitaire Ziekenhuizen KU Leuven; Helmholtz Zentrum München; Skane University... and other collaborators

Recruiting

Anti-viral Action Against Type 1 Diabetes Autoimmunity

Diabetes Mellitus, Type 1

Belgium, Germany, Sweden
NEXBIOME THERAPEUTICS

Not yet recruiting

Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product in Women With Acute Vaginal Infection (ELINA)

Bacterial Vaginosis | Vulvovaginal Candidiasis
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Dose Optimization of Caffeine for HIE

Hypoxic-Ischemic Encephalopathy

United States
BioNTech SE

Not yet recruiting

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

Small-cell Lung Cancer | Extensive-stage Small-cell Lung Cancer
BioNTech SE

Not yet recruiting

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Triple Negative Breast Cancer | Locally Advanced Breast Cancer
University of Alberta

Not yet recruiting

LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM) (WISDOM)

Acute Kidney Injury | Dialysis; Complications
University Hospital, Clermont-Ferrand
Grünenthal GmbH

Not yet recruiting

Capsaicin in Digital Osteoarthritis Versus Control (CADOR)

Neuropathic Pain | Osteoarthritis Hand

France
LEO Pharma

Not yet recruiting

A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968

Joint Pain | Gout Flares | Joint Inflammation
Mohammad Farris Iman Leong Bin Abdullah

Not yet recruiting

Efficacy and Safety of Low-dose Laser Acupuncture on Treating Insomnia Associated With Major Depressive Disorder

Insomnia | Major Depressive Disorder
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

A Safety and Immunogenicity Trial of a Respiratory Syncytial Virus Vaccine, LYB005 in Healthy Adults

Respiratory Syncytial Virus (RSV) | RSV Infection
Fujian Cancer Hospital

Not yet recruiting

Double Dose of Third-generation EGFR-TKI Plus Intrathecal Pemetrexed Versus Double Dose of Third-generation EGFR-TKI in Patients With LM Progression Following the Treatment of Routine Dose of Third-generation EGFR-TKI

Leptomeningeal Metastasis

China
Sinovac Biotech Co., Ltd

Not yet recruiting

Booster Dose of sIPV Co-administered With MMR and HepA-I.

Poliomyelitis

China
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma.

Neuroendocrine Carcinoma

China
Nuritas Ltd

Recruiting

A Study to Determine the Safety and Tolerability of a Range of Doses of PeptiControl in Pre-diabetic Individuals

Overweight | Pre Diabetes

India
Innovative Molecules GmbH

Recruiting

Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy Volunteers

Herpes Simplex Virus

Germany
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

A Study of Single and Multiple Doses HRS9531 Tablets in Healthy Subjects

Overweight or Obesity; Type 2 Diabetes

China
Cairo University

Recruiting

Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.

Perioperative Pain Management

Egypt
Hookipa Biotech GmbH

Not yet recruiting

Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART

Human Immunodeficiency Virus (HIV) Infection

United States
Sichuan University

Recruiting

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

NSCLC | PD-1 Inhibitor | Leptomeningeal Metastasis | Low Dose Radiotherapy

China
GlaxoSmithKline

Recruiting

A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults

Influenza, Human

United States
Ironshore Pharmaceuticals and Development, Inc

Not yet recruiting

Ph3 Multicenter, 3wk RDBPC Efficacy, Safety & PK Study of Evening Dosed MPH HCl ER Capsules (HLD200) in Children 4-5 Yr With ADHD

Attention Deficit Hyperactivity Disorder
Merck Sharp & Dohme LLC

Not yet recruiting

Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

Metastatic Breast Cancer
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study (IVORY-FINALE)

Acute Coronary Syndromes

United Kingdom
Bayer
Regeneron Pharmaceuticals

Recruiting

A Study to Learn More About How Well 8 Milligram Aflibercept Works and How Safe it is in Chinese Participants With Diabetic Macular Edema (PHOTONiC)

Diabetic Macular Edema

China, Hong Kong
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Echocardiographic Measurement of Myocardial Work (MYOLOAD)

Intensive Care Unit Syndrome | Cardiovascular Physiological Phenomena

France
University of Kansas Medical Center

Not yet recruiting

Dose-escalation Study of Ultra-high Dose Ablative Radiosurgery With Immunotherapy for Bulky Metastatic Cancer Patients

Solid Tumor

United States
University of Minnesota

Recruiting

Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis

Cryptococcal Meningitis

Uganda
University of Cincinnati

Not yet recruiting

Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

Cancer | Metastatic Cancer | Locally Advanced Solid Tumor | Locally Advanced | Locally Advanced Carcinoma

United States
Vaxxas Pty Ltd
Biomedical Advanced Research and Development Authority

Not yet recruiting

Influenza A (H7N9) Vaccine Delivered Intradermally by High-density Microarray Patch (HD-MAP) (HD-MAP)

H7N9 Influenza

Australia
NMD Pharma A/S

Not yet recruiting

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis (SYNAPSE-MG)

Myasthenia Gravis | Myasthenia Gravis, MuSK
Instituto Nacional de Investigacao em Saude, Angola
FUNDAÇAO CALOUSTE GULBENKIAN; FUNDACIÓN BANCARIA CAIXA D'ESTALVIS I PENSIONS... and other collaborators

Recruiting

LEARNER- Low dosE AspiRiN prEterm tRial (Angola) (LEARNER)

Pregnancy Complications | Pregnancy Related | Sickle Cell Disease | Pre-Eclampsia

Angola
University of Florida
Cord for Life, Inc.

Recruiting

Open Label Dose Ranging Study Assessing the Safety of Cord Blood Product in Sacroiliac Joint Syndrome (SIJ) (SIJ)

Pain, Back | Sacroiliac; Backache

United States
AbbVie

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABBV-1088 Oral Dose in Healthy Adult Participants.

Healthy Volunteers

United States
Tongji Hospital
Xinxiang Central Hospital

Not yet recruiting

Effect of Equivalent Dose Sufentanil and Afentanil in Bronchoscopic Treatment (EOEDSAAIBT)

Effect of Drug

China
Serum Institute of India Pvt. Ltd.

Recruiting

Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV

Hepatitis B Immunization | Diptheria Immunization | Tetanus Immunization | Pertussis Immunization | Haemophilus Influenzae Type B Immunization | Polio Immunization

Bangladesh, India
Tongji Hospital

Not yet recruiting

Oliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid Study

Postoperative Analgesia
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Sanofi

Recruiting

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (ESTUARY)

Dermatitis Atopic

United States
Wave Life Sciences Ltd.

Recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency

Canada

Search clinical trials for: gene dose

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Macedonia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations