Search clinical trials for: high platelet reactivity

Total 28294 results

Yonsei University

Recruiting

Tailored Anti-platelet Therapy After DES Implantation in High-risk Patients

Coronary Artery Disease

Korea, Republic of
Azienda Ospedaliera Universitaria Policlinico "G...
Gianluca Di Bella; Antonio Micari; Giampiero Vizzari; Giorgio Quadri; Greca Zanda; Ferdinando...

Recruiting

De-escalating Antiplatelet Therapy to Assess Platelet Reactivity and Outcomes in High Bleeding Risk Patients With Recent ACS (DESC-HBR)

Coronary Artery Disease | Acute Coronary Syndrome | Dual Antiplatelet Therapy

Italy
University of Florida

Recruiting

A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction

Coronary Artery Disease

United States
University Hospital, Caen
Terumo Medical Corporation

Completed

Evaluation of Myocardial Reperfusion After Primary PCI in Patients With High Platelet Reactivity Treated by Cangrelor or Not (ERMIT)

ST-elevation Myocardial Infarction

France
Andres Iñiguez Romo

Completed

Platelet REACtivity According to TICagrelor Dose After Transcatheter AorticValve Implantation (REACTIC-TAVI)

Symptomatic Aortic Stenosis

Spain
University of Florida
Amgen

Completed

Impact of Evolocumab on the Effects of Clopidogrel in Patients With High On-Treatment Platelet Reactivity

Atherosclerotic Cardiovascular Disease

United States
Nanjing First Hospital, Nanjing Medical University

Withdrawn

Ticagrelor Versus High-dose Clopidogrel in Patients With High Platelet Reactivity on Clopidogrel After PCI (PL-PLATELET)

Coronary Artery Disease

China
Beijing Neurosurgical Institute

Completed

Application of Platelet Function Test in Prevention of Ischemic Events After Stent Placement in Intracranial Aneurysms (APISIA Trail)

Stents | Unruptured Intracranial Aneurysm | Antiplatelet Drugs

China
The First Affiliated Hospital with Nanjing Medical...
National Natural Science Foundation of China

Completed

OPTImal Management of Antithrombotic Agents: OPTIMA-2 Trial (OPTIMA-2)

Coronary Artery Disease

China
The University of The West Indies

Completed

The Effects of loW Dose tIcagrelor on Platelet Function Testing in Patients With Stable Coronary arTery Disease (TWIST)

Platelet Dysfunction Due to Drugs

Trinidad and Tobago
Taipei City Hospital

Completed

Platelet Reactivity (High On-Treatment Platelet Reactivity) as Guidance for APT (Antiplatelet Therapy) Adjustment After PCI (Percutaneous Coronary Intervention)

PRU(Platelet Reactivity Unit) | APT(Antiplatelet Therapy) | HOTPR(High on Treat Platelet Reactivity)

Taiwan
Taipei City Hospital

Completed

Downstream Molecular Signals of P2Y12 Receptors in Hyporeactive Patients Under Clopidogrel Treatment A Possible Mechanism of HOTPR(High On-Treatment Platelet Reactivity)

Stable Angina

Taiwan
Medical University of Vienna

Unknown

High "on Treatment" Platelet Reactivity in the Intensive Care Unit

Critical Illness

Austria
Dong-A University

Completed

PRAsugrel or clopIdogrel In Acute Coronary SyndromE With CYP2C19 GENEtic Variants (PRAISE-GENE)

Acute Coronary Syndromes

Korea, Republic of
The Royal Wolverhampton Hospitals NHS Trust

Completed

The Effect of IV Cangrelor and Oral Ticagrelor Study

ST-segment Elevation Myocardial Infarction (STEMI) | Acute Coronary Syndrome (ACS) | Unstable Angina (UA) | High On-treatment Platelet Reactivity (HTPR) | Microvascular Obstruction (MVO) | Thrombolysis in Myocardial Infarction (TIMI)

United Kingdom
First Affiliated Hospital of Harbin Medical University

Unknown

Half-dose Ticagrelor Overcomes High-dose Clopidogrel in Acute Coronary Syndrome Patients With High On-Clopidogrel Platelet Reactivity

Coronary Artery Disease | Clopidogrel, Poor Metabolism of

United States
University Hospital Ostrava

Completed

REsistance to Aspirin and Clopidogrel in acuTe Myocardial Infarction (REACT-MI)

Acute Myocardial Infarction

Czech Republic
Wuhan Asia Heart Hospital

Completed

High On-treatment Platelet Reactivity Identified by Multiple Platelet Function Assay (HOPEmultiPFA)

Acute Coronary Syndrome

China
Han Yaling

Completed

Tongxinluo Improve High on Clopidogrel Platelet Reactivity Patients With Coronary Heart Disease (Talent)

Coronary Artery Disease

China
Shenyang Northern Hospital

Completed

Study of Policosanol to Improve Platelet Reactivity After Percutaneous Coronary Stent Implantation (PCI) (spirit)

Coronary Artery Disease

China
University of Patras

Completed

Ticagrelor vs High Dose Clopidogrel in Patients With ST Elevation Myocardial Infarction Post Fibrinolysis

ST Elevation Myocardial Infarction | Fibrinolysis | P2Y12 Inhibitor

Greece
Dong-A University

Completed

Reloading Prasugrel or Clopidogrel on High Platelet Reactivity Before Percutaneous Coronary Intervention (PRAISE-HPR)

Acute Coronary Syndrome

Korea, Republic of
LifeBridge Health
AstraZeneca

Unknown

Overcoming High On-Treatment Platelet Reactivity (HPR) During Prasugrel Therapy With Ticagrelor (HEIGHTEN)

Coronary Artery Disease

United States
University of Pecs

Completed

Prasugrel Versus Clopidogrel to TREAT High Platelet Reactivity (TREAT-HPR)

Acute Coronary Syndrome

Hungary
Royal Brompton & Harefield NHS Foundation Trust
University Hospital Tuebingen

Terminated

Evaluating Additional Platelet Inhibition in Patients With High Platelet Reactivity Undergoing Percutaneous Coronary Intervention (APACS-HPR)

Cardiovascular Disease | Acute Coronary Syndrome

Germany
University of Zagreb
Clinical Hospital Centre Zagreb; Ministry of Science, Education and Sport,...

Completed

Continuous Clopidogrel Dose Adjustment in Acute Coronary Syndrome Patients With High On-treatment Platelet Reactivity

Acute Coronary Syndrome

Croatia
University of Patras

Completed

High (100mg) Versus Standard (60mg) Loading Dose of Prasugrel in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)

Platelet Reactivity

Greece
University of Patras

Completed

High on Treatment Platelet Reactivity Following Peripheral Endovascular Procedures (PRECLOP)

Influence of PRU Values on Primary Outcome

Greece
University of Patras

Completed

Prasugrel 5mg Versus High Dose Clopidogrel in Clopidogrel Resistant Patients Aged ≥75 Years and/or Weighing <60 kg Post Percutaneous Coronary Intervention (PCI)

Platelet Reactivity

Greece
Ruttonjee Hospital

Completed

Effect of Amlodipine on Anti-platelet Drug Effect in Patients With Coronary Artery Disease

Ischemic Heart Disease

China
Assistance Publique Hopitaux De Marseille

Completed

Impact of Clopidogrel Dose Adjustment According to Platelet Reactivity Monitoring in Patients With High on Treatment Platelet Reactivity Undergoing Percutaneous Coronary Intervention

Acute Coronary Syndromes

France
Gennaro Sardella

Completed

Therapy With High Clopidogrel Dose or Prasugrel Standard Dose Reduces the Platelet Reactivity in Patients With Genotype Variation RESET GENE Trial (RESET GENE)

Acute Coronary Syndrome

Italy
Ospedale Misericordia e Dolce

Completed

Atorvastatin and Clopidogrel HIgh DOse in Stable Patients With Residual High Platelet Activity (ACHIDO)

Stable Angina

Italy
University of Patras

Completed

Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Reactivity in Patients With ST-elevation Myocardial Infarction (STEMI) (PRO-GR-4)

Myocardial Infarction

Greece
University of Patras

Completed

Prasugrel Versus High Dose Clopidogrel in Patients With Stable Coronary Artery Disease and High Platelet Reactivity While on Chronic Clopidogrel Treatment

Coronary Artery Disease (CAD)

Greece
University of Pecs

Terminated

Doubling the Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity (DOSER)

Stable Angina Pectoris | Ad Hoc Percutaneous Coronary Intervention

Hungary
Gyeongsang National University Hospital

Completed

Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction (AMI) Patients According to CYP2C19 Polymorphism (ACCELAMI2C19)

Myocardial Infarction

Korea, Republic of
Gyeongsang National University Hospital

Unknown

Comparison of Platelet Inhibition With Adjunctive Cilostazol Versus High Maintenance-Dose Clopidogrel According to Hepatic Cytochrome 2C19 Allele (CYP2C19) Polymorphism (ACCEL2C19)

Coronary Artery Stenosis | Maximal Platelet Aggregation | Late Platelet Aggregation | High Post-Treatment Platelet Reactivity

Korea, Republic of
Ankara City Hospital Bilkent

Recruiting

Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric

Anesthesia | Child, Only | Cerebral Oxygenation | Cerebral Hypoxia | Inhalation; Vapor | Peripheral Oxygenation

Turkey
Beijing Tiantan Hospital

Not yet recruiting

Tirofiban for Patients With intraCranial Artery Stenosis and High-risk Acute Non-disabling Cerebrovascular Events(CHANCE-4）

TIA | Ischemic Stroke, Acute | Symptomatic Intracranial Artery Stenosis

China
Western Norway University of Applied Sciences

Recruiting

Cardiovascular Reactivity to Physical Stress (REACT)

Stress, Physiological | Blood Pressure

Norway
AOP Orphan Pharmaceuticals AG
GCP-Service International Ltd. & Co. KG; ANOVA CRO s.r.o.; PharmaLex Belgium; Aixial...

Recruiting

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

Pulmonary Arterial Hypertension

Austria, Spain, France, Germany, Italy, Czechia, Hungary, Poland, Portugal, Romania
Helwan University

Not yet recruiting

The Effect of PRP on Wound Healing in High Risk Patients Undergoing Abdominal Hysterectomy

Wound Heal | PRP | Abdominal Wound
Woo-Keun Seo

Not yet recruiting

Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk Patients

Carotid Artery Diseases
University of Florida
Scott R. MacKenzie Foundation

Recruiting

Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention

Coronary Artery Disease

United States
Fayoum University

Not yet recruiting

I-PRF After Arthrocentesis Plus Botox Injection to Lateral Pterygoid Muscle in Treatment of Anterior Disc Displacement

TMJ Disc Disorder | TMJ Pain
Norwegian University of Science and Technology
St. Olavs Hospital; Alesund Hospital

Not yet recruiting

Biological Changes Associated With High Risk of Preeclampsia in Nulliparous Women (PRERISK)

Preeclampsia

Norway
Karolinska Institutet

Recruiting

A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.

Osteoarthritis Thumb

Sweden
University of California, San Francisco
Jazz Pharmaceuticals

Not yet recruiting

Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma

Thrombotic Microangiopathies | Neuroblastoma | High-risk Neuroblastoma | Transplant-Associated Thrombotic Microangiopathy

United States
Peking University People's Hospital
Peking University First Hospital; Beijing Friendship Hospital; Chinese PLA General... and other collaborators

Recruiting

Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China

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