Search clinical trials for: immunization efficacy

Total 35741 results

BioNTech SE

Recruiting

A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria

Malaria

United States
Tongji Hospital

Recruiting

Safety and Analgesic Efficacy of a Modified Auriculotemporal Nerve Block

Safety and Efficacy | Scalp Nerve Block

China
University of Yaounde 1
Biotechnology Center (BTC), University of Yaounde I, Cameroon; National Malaria... and other collaborators

Not yet recruiting

Efficacy and Safety of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine in Cameroon

Malaria
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae

Gonorrhea Male

United States
Biopharma Plasma LLC
Ivano-Frankivsk National Medical University; State Institution, Zaporizhzhia...

Recruiting

Human Anti-D (rh) Immunoglobulin (Rhesoglobin) Efficacy, Safety and Some Pharmacokinetics Parameters in Pregnant Women

Pregnancy Related

Ukraine
Janssen Research & Development, LLC

Completed

Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide

Depressive Disorder, Major

United States, France, Italy, Spain, Hungary, Belgium, Brazil, Bulgaria, Poland
The University of Texas Medical Branch, Galveston
Cancer Prevention Research Institute of Texas

Active, not recruiting

GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose

Efficacy | Human Papilloma Virus | Immunization

United States
Zhuhai Trinomab Pharmaceutical Co., Ltd.

Completed

Study to Compare the Efficacy and Safety of Passive Immunization With TNM002 Injection and Human Tetanus Immunoglobulin as Prophylaxis Against Tetanus

Tetanus

China
Sanofi
Regeneron Pharmaceuticals

Completed

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation (BOREAS)

Chronic Obstructive Pulmonary Disease

Spain, Argentina, China, Mexico, Canada, Ukraine, Israel, Italy, Czechia, Korea, Republic of, Bulgaria, Chile, Denmark, Finland, Germany, Hungary, Japan, Poland, Romania, Russian Federation, Slovakia, Sweden, Turkey, United States
BioCryst Pharmaceuticals

Completed

Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAE (APeX-2)

Hereditary Angioedema | HAE

United States, Austria, Canada, Czechia, France, Germany, Hungary, North Macedonia, Romania, Spain, United Kingdom
Radboud University Medical Center
The PATH Malaria Vaccine Initiative (MVI)

Terminated

Safety and Efficacy of NF135 CPS Immunization (CPS135)

Malaria,Falciparum | Controlled Human Malaria Infection | Immunization; Infection

Netherlands
Centre Henri Becquerel

Completed

Efficacy of COVID-19 Vaccination in Patientstreated With Anti-CD20 for Follicular Lymphoma or Mantle Cell Lymphoma (VAXIMAB)

Follicular Lymphoma | Mantle Cell Lymphoma

France
Azidus Brasil
Panamerican Medical Supply

Suspended

Clinical Efficacy of Postpartum Immunization of Rh and Coombs Negative Women With Sensitization Risk.

Pregnancy; Fetomaternal Hemorrhage

Brazil
Materia Medica Holding

Completed

Efficacy and Safety of Ergoferon for COVID-19 Prevention During Vaccination Against SARS-CoV-2

Immunization Against COVID-19

Russian Federation
Hospital Galdakao-Usansolo

Terminated

Efficacy of the Infusion of Donor Plasma in COVID-19 Infection

COVID-19

Spain
Children's Hospital Medical Center, Cincinnati
Johns Hopkins Bloomberg School of Public Health; Bill and Melinda Gates Foundation and other collaborators

Completed

Field Trial of Maternal Influenza Immunization in Asia (Mothers'Gift)

Influenza Human

Nepal
Kenya Medical Research Institute
Centers for Disease Control and Prevention

Completed

Therapeutic Efficacy Study of AL and DP in Western Kenya

Malaria,Falciparum
Limited Liability Company Pharm Aid

Completed

Reactogenicity, Safety and Immunological Efficacy of the Live, Pentavalent Rotavirus Vaccine in Childhood Immunization

Rotavirus Infection

Russian Federation
Janssen Vaccines & Prevention B.V.

Completed

An Exploratory Study to Evaluate the Prophylactic Efficacy of a Single Immunization of Ad26.RSV.preF Against Respiratory Syncytial Virus Infection in a Virus Challenge Model in Healthy 18 to 50 Year-old Adults

Healthy

United Kingdom
Biomat USA, Inc.
Axio Research. LLC; Hammond Clinical Trial Consulting, LLC

Completed

Safety and Efficacy of Two Tetanus-Diphtheria Vaccines for a Donor Hyper Immunization Program

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites in Healthy African Adults in Mali

Malaria

Mali
Novavax
Bill and Melinda Gates Foundation

Completed

A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization

Respiratory Syncytial Virus Infections

United States, Argentina, Australia, Bangladesh, Chile, Mexico, New Zealand, Philippines, South Africa, Spain, United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Efficacy of the Live Attenuated Tetravalent Dengue Vaccine Against DENV-2 and DENV-3 Challenge

Dengue

United States
Axon Neuroscience SE

Completed

24 Months Safety and Efficacy Study of AADvac1 in Patients With Mild Alzheimer's Disease (ADAMANT)

Alzheimer's Disease

Poland, Austria, Czechia, Germany, Romania, Slovakia, Slovenia, Sweden
University Hospital Tuebingen
Sanaria Inc.

Completed

Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis

Malaria
Johns Hopkins Bloomberg School of Public Health
United States Department of Defense; Naval Medical Research Center

Completed

Efficacy of B7A BSIgG Against E. Coli Strain B7A Challenge

Healthy Volunteer

United States
Crucell Holland BV
Retroscreen Virology Ltd.

Completed

Evaluation of the Protective Efficacy and Safety of CR8020 in an Influenza Challenge

Influenza

United Kingdom
Mitsubishi Tanabe Pharma Corporation
The Research Foundation for Microbial Diseases of Osaka University

Completed

Safety and Efficacy of BK1310 Intramuscular Injection in Healthy Infants

Immunization

Japan
Johns Hopkins Bloomberg School of Public Health
Naval Medical Research Center; Uniformed Services University of the Health...

Completed

Efficacy of Rifaximin in Preventing Campylobacteriosis

Diarrhea | Dysentery | Enteric Campylobacteriosis

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
Hospices Civils de Lyon

Unknown

Vaccines Immunogenicity in Renal, Hepatic, Cardiac or Pulmonary Transplanted Children (COVAGREF)

Transplantation

France
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Protective Efficacy of a Single Dose of the Live Attenuated Tetravalent Dengue Vaccine TV005 to Protect Against Infection With rDEN3Δ30

Dengue

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Protective Efficacy of a Single Dose of a Trivalent Live Attenuated Dengue Vaccine to Protect Against Infection With DENV-2

Dengue

United States
Sanaria Inc.
German Federal Ministry of Education and Research; Institute of Tropical Medicine...

Completed

Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under Chemoprophylaxis

Malaria | Plasmodium Falciparum Malaria

Germany
Johns Hopkins Bloomberg School of Public Health
Naval Medical Research Center

Completed

Safety and Efficacy of Bovine Milk Immunoglobulin Against CS17 and CsbD (BIgGII)

Travelers' Diarrhea

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of the Safety and Efficacy of a Single Dose of a Dengue Vaccine (TV005) in Healthy Adults

Dengue

United States
Isarna Therapeutics GmbH

Terminated

Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma (SAPPHIRE)

Glioblastoma | Anaplastic Astrocytoma

Spain, Taiwan, Korea, Republic of, United States, Hungary, Germany, Argentina, Brazil, India, Canada, Austria, France, Mexico, Poland, Russian Federation, United Kingdom
Crucell Holland BV
National Institutes of Health (NIH); Division of Microbiology and Infectious...

Withdrawn

Assessment of Efficacy of CR8020 and CR6261, Monoclonal Antibodies, Against Influenza Infection

Influenza

United States, Australia, Canada, France, Germany, Spain, Belgium, Bulgaria, Netherlands, Brazil, South Africa, Sweden
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; European Union; Kilimanjaro Christian Medical...

Completed

Treatment Efficacy and Malaria TRANSmission After Artemisinin Combination Therapy 2 (TRANSACT2) (TRANSACT2)

Malaria

Kenya
Nematollah Jonaidi Jafari

Unknown

Effects of Short-term Atorvastatin Treatment on Vaccination Efficacy in Nonresponder Persons to Hepatitis B Vaccine

Hepatitis B | Vaccination Failure

Iran, Islamic Republic of
TD Vaccines A/S
Johns Hopkins Bloomberg School of Public Health; Pierrel Research USA, Inc.

Completed

Safety and Efficacy Study of a Vaccine Against Enterotoxigenic Escherichia Coli (ETEC) to Prevent Moderate to Severe Diarrhea

Diarrhea

United States
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases

Rheumatoid Arthritis | Systemic Vasculitis | Juvenile Idiopathic Arthritis | Antiphospholipid Syndrome | Sjögren's Syndrome | Spondyloarthritis | Systemic Lupus Erythematosus (SLE) | Systemic Sclerosis (SSc) | Dermatomyositis (DM) | DMixed Connective Tissue Disease | Juvenile SLE | Juvenile DM

Brazil
Johns Hopkins Bloomberg School of Public Health
Walter Reed Army Institute of Research (WRAIR); Naval Medical Research Center

Completed

Efficacy of Anti-CFA/I and CfaE Bovine Milk Immunoglobulin Against Challenge With H10407 ETEC Expressing CFA/I (BIgGI)

Diarrhea

United States
Univax Biologics Inc

Completed

A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS Patients

HIV Infections | Cryptosporidiosis

United States
American National Red Cross

Completed

A Pilot Study to Obtain Preliminary Information Regarding the Efficacy and Safety of the Combination of Immune Globulin and Ganciclovir as Compared to Ganciclovir Alone in the Treatment of Sight-Threatening CMV Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Vertex Pharmaceuticals Incorporated

Not yet recruiting

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older

Cystic Fibrosis
Tongji Hospital
The First People's Hospital of Jingzhou; Wuhan Central Hospital; Wuhan No.1 Hospital and other collaborators

Recruiting

Safety, Efficacy, and Compliance of Telitacicept in the Treatment of Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

China
Xijing Hospital

Not yet recruiting

Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer

Sintilimab | Neoadjuvant Chemotherapy | Locally Advanced Gastric Cancer
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

the Efficacy and Safety of Total Myeloid Irradiation (TMI) in the Treatment of Adult Acute Lymphoblastic Leukemia (TMI)

Acute Lymphoblastic Leukemia
Institut Curie

Not yet recruiting

Efficacy of Personalized Tumorogram-based Therapy in Cancer Established From Patient-derived Organoid (AVATAR)

Metastatic Breast Cancer

France

Search clinical trials for: immunization efficacy

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