Search clinical trials for: initial therapy

Total 52300 results

Qianfoshan Hospital

Recruiting

Study on the Efficacy and Safety of Conversion Therapy in Patients With Initially Unresectable Hepatocellular Carcinoma

Carcinoma, Hepatocellular

China
Fudan University

Recruiting

Initial CDK 4/6 Inhibitor Plus Endocrine Therapy Versus Initial Chemotherapy in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer

Breast Cancer

China
AOP Orphan Pharmaceuticals AG
GCP-Service International Ltd. & Co. KG; ANOVA CRO s.r.o.; PharmaLex Belgium; Aixial...

Recruiting

Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I Patients (TripleTRE)

Pulmonary Arterial Hypertension

Austria, Spain, France, Germany, Italy, Czechia, Hungary, Poland, Portugal, Romania
St. Jude Children's Research Hospital

Not yet recruiting

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mixed Phenotype Acute Leukemia

United States
Methodist Health System

Recruiting

Dual Antiplatelet Therapy (DAPT) in Patients With Baseline Thrombocytopenia

Baseline Thrombocytopenia

United States
Yi Han
Qianfoshan Hospital

Recruiting

Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

Heart Failure | Efficacy | Safety | Levosimendan | Milrinone

China
yue junhan

Recruiting

Efficacy and Safety of Combined With Immunotherapy After Induction Therapy With Chemotherapy and Targeted Therapy in the First-line Treatment of Microsatellite Stable (MSS) Initially Unresectable Metastatic Colorectal Cancer (FOBECAMS)

Colorectal Cancer

China
Mayo Clinic

Recruiting

A Comparative Clinical Study to Determine the Optimal Initial Therapy for Multiple Myeloma

Multiple Myeloma

United States
West China Hospital

Recruiting

A Clinical Study Evaluating the Safety, Tolerability, and Initial Efficacy of Single Intravenous Infusion of JWK007 in Patients With Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

China
FengYan Jin

Not yet recruiting

A Perspective, Single Center Study of the MRD-tailored Therapy in Patients With Newly Diagnosed Multiple Myeloma With Persistent Minimal Residual Disease After Initial Treatment (MRD)

Multiple Myeloma | Minimal Residual Disease
Mississippi State University

Recruiting

An Initial Test of Prototype Mobile App Interventions for Decluttering

Hoarding

United States
Alice Chung

Not yet recruiting

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases

Breast Cancer | Mastectomy; Lymphedema | Female Breast Cancer | Axilla; Breast | Tumor, Breast | Axillary Nodal Disease
Universitaire Ziekenhuizen KU Leuven

Not yet recruiting

The Additional Effect of Tongue Scraping on Halitosis Parameters in Initial Periodontal Therapy

Periodontitis | Halitosis | Tongue Condition
Emory University
National Institute of Mental Health (NIMH)

Recruiting

Dopaminergic Therapy for Anhedonia - 2 (DTA-2)

Depression | Anhedonia

United States
Roswell Park Cancer Institute

Recruiting

EGF-Depleting Therapy CIMAvax-EGF in Combination With Standard Therapy for RAS- and BRAF Wild-Type Metastatic Colorectal Cancer

Colo-rectal Cancer

United States
Peking University Third Hospital
Capital Medical University

Not yet recruiting

Human Dental Pulp Mesenchymal Stem Cells for the Treatment of Chronic Periodontitis Patients

Periodontitis

China
Lithuanian University of Health Sciences
Klaipėda University; Minneapolis Heart Institute; Kreiskrankenhaus Rotenburg...

Recruiting

Patient Autonomy and Statin Therapy Adherence (PASTA)

Drug Adherence

Lithuania
University of Rijeka

Recruiting

Change in Gingival Volume and Quality of Life Due to Initial Periodontal Therapy in Smokers

Periodontitis

Croatia
Duke University

Recruiting

Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

Heart Failure

United States
C4 Therapeutics, Inc.

Recruiting

A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors

Melanoma | NSCLC | Solid Tumors | CRC | ATC

United States, Spain, France
Weill Medical College of Cornell University
Genentech, Inc.; BeiGene

Recruiting

Zanubrutinib and Venetoclax as Initial Therapy for Chronic Lymphocytic Leukemia (CLL) With Response-based Obinutuzumab

Leukemia, Lymphocytic, Chronic, B-Cell

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia (AML) Following Initial Treatment (ERASE)

Leukemia, Myeloid, Acute
Makerere University

Recruiting

Ivermectin-artemisinin Combination Therapy for Eradication of Malaria (IVIME)

Malaria

Uganda
LanZhou University
Beigene (Beijing) Biotechnology Co., Ltd

Not yet recruiting

Zanubrutinib in Maintenance Therapy of DLBCL Patients With Initial Remission

Diffuse Large B-cell Lymphoma (DLBCL)

China
University of Erlangen-Nürnberg Medical School

Recruiting

Effect of the CFTR-modulating Triple Therapy Elexacaftor - Tezacaftor - Ivacaftor

Cystic Fibrosis

Germany
The First Affiliated Hospital with Nanjing Medical...
West China Hospital; Fujian Medical University Union Hospital; Chinese Academy... and other collaborators

Recruiting

LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB (LIT-HF)

Heart Failure | Left Bundle-Branch Block | Non-ischemic Cardiomyopathy

China
National Cancer Institute (NCI)

Not yet recruiting

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm | Acute Myeloid Leukemia Post Cytotoxic Therapy
Jiandong Zhang

Recruiting

Low-dose Radiotherapy Combined With Conventional Radiotherapy After Immunotherapy Failure (FL001)

Cancer Patients

China
University Hospital, Montpellier

Recruiting

Triple BRAFinh/MEKinh /antiPD1 Combined Therapy in Patients With BRAF Mutated Melanoma With Central Nervous System Metastasis

Metastatic Melanoma

France
Maxwell Biomedical

Recruiting

Initial Experience With Spatial Resynchronization Therapy in Patients With Atrial Fibrillation (SR-TheAF)

Atrial Fibrillation

Georgia
Sven Löffeler
Oslo University Hospital; Klinbeforsk

Recruiting

Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer (GrandP/SPCG19)

Prostate Cancer

Norway, Denmark, Finland
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Comparative Effectiveness of PAL Based-therapy as Initial ET Versus PAL Based-therapy After ChT for HR+/HER2- ABC

Hormone Receptor Positive Advanced Breast Cancer

China
Peking Union Medical College Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Xinda Biopharmaceutical Group

Not yet recruiting

Sintilimab Combined With Anlotinib Therapy for Initially Unresectable Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung
Assistance Publique - Hôpitaux de Paris
BioMérieux

Recruiting

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter Trial (MULTI-EXA)

Acute Exacerbation of COPD

France
Augusta University
H. Jean Khoury Cure CML Consortium

Recruiting

Asciminib as Initial Therapy for Patients With Chronic Myeloid Leukemia in Chronic Phase (ALERTCML)

Leukemia, Myeloid | Chronic Myeloid Leukemia, Chronic Phase | Adult CML | Leukemia,Myeloid, Chronic

United States
Assistance Publique - Hôpitaux de Paris
Advanz Pharma; Centre Hospitalier de Perigueux; CHU de Nantes; Centre National...

Recruiting

Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus (DALICATH)

Staphylococcus Aureus Infection | Catheter Bacteremia

France
Sun Yat-sen University

Recruiting

Different Initial Insulin Dose Regimens on Time to Achieve Glycemic Targets and Treatment Safety in SIIT

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Metabolic Disease

China
Medical College of Wisconsin

Recruiting

Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique

Brain Metastases

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
AbbVie

Recruiting

Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
The Filatov Institute of Eye Diseases and Tissue...
Odessa National Medical University; Mykolaiv Region Ophthalmogical Hospital; Central... and other collaborators

Recruiting

Brolucizumab for CNV Associated With Pathologic Myopia (COASTUAbaCNV)

Pathologic Myopia

Ukraine
Janssen Research & Development, LLC

Recruiting

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5)

Multiple Myeloma

United States, Korea, Republic of, Denmark, Czechia, Israel, Switzerland, Belgium, United Kingdom, Japan, Argentina, Sweden, Canada, Spain, Germany, Netherlands, France, Brazil, Greece, Poland, Ireland, Hungary, Portugal, Australia, F... and more
Medical College of Wisconsin

Recruiting

MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer

Rectal Adenocarcinoma

United States
National Cancer Institute (NCI)

Recruiting

Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

Lymphoplasmacytic Lymphoma | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma | Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Grade 3b Follicular... and other conditions

United States
First Affiliated Hospital of Harbin Medical University

Not yet recruiting

Effect of Combination Therapy on SCLC After Initial Treatment Failure

Small-cell Lung Cancer
Assistance Publique - Hôpitaux de Paris
Janssen, LP

Recruiting

Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (IMPACT-CTEPH)

Chronic Disease | Inoperable Disease | Thromboembolic Pulmonary Hypertension

France
University of Illinois at Chicago

Not yet recruiting

Relationship of the Microenvironment and Male Fertility

Male Infertility | Male Hypogonadism

United States
Mayo Clinic

Recruiting

Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy

Sleep Apnea Syndromes | Sleep Apnea, Obstructive | Obesity Hypoventilation Syndrome (OHS)

United States
Fudan University

Recruiting

Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases

Colorectal Cancer | Liver Metastases

China
Tianjin Medical University Cancer Institute and...
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Conversion Therapy of Camrelizumab Plus Chemoradiotherapy in Participants With Initial Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Gastric Cancer
Peking University Third Hospital

Recruiting

The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients：A Prospective Cohort Study (INITIAL)

Gout

China

Search clinical trials for: initial therapy

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