Search clinical trials for: intraoperative cisplatin

Total 5709 results

Privo Technologies
National Cancer Institute (NCI)

Recruiting

Safety and Efficacy Study of PRV211 in Subjects With Oral Squamous Cell Carcinoma

Oral Squamous Cell Carcinoma

United States
Brigham and Women's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

MAGIC AKI: Magnesium for the Prevention of HIOC-Associated AKI (MAGIC-AKI)

Mesothelioma

United States
University Hospital, Ghent

Completed

Intraoperative Intraperitoneal Chemoperfusion to Treat Peritoneal Minimal Residual Disease in Stage III Ovarian Cancer (OvIP1)

Ovarian Cancer | Primary Peritoneal Cancer

Belgium
University of Arkansas
Janssen, LP

Active, not recruiting

2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy

Multiple Myeloma

United States
Cantonal Hospital of St. Gallen

Terminated

Hyperthermic Intraoperative Intraperitoneal Chemotherapy of Recurrent Ovarian Cancer - A Feasibility Study

Epithelial Ovarian Cancer | Fallopian Tube Carcinoma

Switzerland
Baylor College of Medicine

Terminated

Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPM

Mesothelioma

United States
Dana-Farber Cancer Institute

Completed

Intravenous Magnesium in Patients Receiving Cisplatin

Mesothelioma

United States
Fundacion para la Formacion e Investigacion Sanitarias...

Unknown

Cytoreduction With or Without Intraoperative Intraperitoneal Hyperthermic Chemotherapy (HIPEC) in Patients With Peritoneal Carcinomatosis From Ovarian Cancer, Fallopian Tube or Primary Peritoneal Carcinoma (CARCINOHIPEC)

Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma | Peritoneal Carcinomatosis From Ovarian Cancer

Spain
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Terminated

Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate

Malignant Pleural Mesothelioma | Pleural Mesothelioma

United States
Eastern Hepatobiliary Surgery Hospital

Completed

Intraoperative Chemotherapy Against Hepatocellular Carcinoma Recurrence

Hepatocellular Carcinoma

China
Baki Topal
Universitaire Ziekenhuizen KU Leuven

Terminated

Cytoreductive Surgery(CRS) Plus Hyperthermic Intraoperative Peritoneal Chemotherapy(HIPC) With Cisplatin to Treat Peritoneal Carcinomatosis From Upper Gastrointestinal Cancer

Gastrointestinal Cancer | Peritoneal Carcinomatosis

Belgium
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate

Malignant Pleural Mesothelioma | Pleural Mesothelioma

United States
University Hospital, Bonn

Unknown

Safety and Pharmacokinetics of Intraoperative Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) With Cisplatin to Treat Platinum-sensitive Recurrent Ovarian Cancer (HIPEC ROC I)

Ovarian Cancer

Germany
Mayo Clinic
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Radiation Therapy, and Sargramostim Before and After Surgery in Treating Patients With Soft Tissue Sarcoma That Can Be Removed By Surgery

Sarcoma | Metastatic Cancer
Wuhan University
NPO Organization to Support Peritoneal Dissemination Treatment; Kishiwada Tokushukai... and other collaborators

Unknown

Surgery Plus Intraoperative Peritoneal Hyperthermic Chemotherapy (IPHC) to Treat Peritoneal Carcinomatosis (IPHC)

Stomach Neoplasms | Neoplasm Metastasis | Colorectal Neoplasms | Mesothelioma

China
Hospital Universitari Vall d'Hebron Research Institute

Recruiting

The Preoperative Administration of ICG Improves Tumor Detection in Patients Undergoing Minimally Invasive Hepatic Resection Guided by Conventional Intraoperative Ultrasound.

Liver Tumor; Surgery

Spain
University Hospital of Split

Recruiting

Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants

Anesthesia | Neuromuscular Blockade | Intraoperative Bleeding | Anesthesia Complication | Post Operative Hemorrhage | Intraoperative Blood Loss

Croatia
Adiyaman University

Recruiting

Gram Stain of the First Urine After Puncture in Percutaneous Nephrolithotomy

Percutaneous Nephrolithotomy

Turkey
University of Texas Southwestern Medical Center
Astellas Pharma Inc

Not yet recruiting

Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer (STAR-EV)

Bladder Cancer
Centre Leon Berard
Groupe Français de Pneumo-Cancérologie

Not yet recruiting

FIRST-NEC (GFPC 01-2022) - Combination of Durvalumab With Etoposide and Platinum (FIRST-NEC)

Large Cell Neuroendocrine Carcinoma of the Lung

France
RenJi Hospital

Recruiting

Concurrent Chemoradiotherapy Followed by PD-1 Inhibitor in Advanced Cervical Cancer

Immunotherapy | Locally Advanced Cervical Carcinoma | Concurrent Chemoradiotherapy

China
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer Using Pathology Biopsies

Glioma

United States
Yang Jianjun, PhD

Not yet recruiting

Serplulimab Combined With Nab-paclitaxel and Cisplatin in Neoadjuvant Therapy for Resectable Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Intraoperative Ultrasound in Crohn's Disease

Crohn Disease
The First Affiliated Hospital of Xiamen University

Recruiting

Genomic Biomarker-guided Neoadjuvant Therapy for Prostate Cancer (SEGNO) (SEGNO)

Oligometastatic Prostate Cancer | Locally Advanced Prostate Cancer

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Advanced KRAS G12D Mutant Solid Tumors

China
Melt Pharmaceuticals
Catalent; Evolution Research Group; MedTrials Incorporated; Pharmalex

Recruiting

A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)

Cataract

United States
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study Comparing BL-B01D1 With Platinum Based Chemotherapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Shanghai JMT-Bio Inc.

Not yet recruiting

JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations

Local Advanced or Metastatic NSCLC
University of Novi Sad

Recruiting

Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery

Acute Kidney Injury

Serbia
Etienne Xavier Keller

Recruiting

Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery (PENIS)

Erection; Incomplete

Switzerland
Weill Medical College of Cornell University
Curium US LLC

Not yet recruiting

Feasibility of Intraoperative Tracing of Meningioma Using [Cu64]DOTATATE

Meningioma

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

Intraoperative Sufentanil and Chronic Postsurgical Pain in Non-major Scheduled Abdominal Surgery (ISPAIN)

Chronic Pain | Abdominal Surgery | Risk Factors | Chronic Postsurgical Pain | Sufentanil

France
Beijing Chest Hospital, Capital Medical University

Not yet recruiting

PD-L1/PD-1 Inhibitors Plus Chemotherapy Versus Chemotherapy Alone for the Neoadjuvant Treatment of Limited-stage SCLC (NeoSCLC-001)

Limited-stage Small-cell Lung Cancer
Hebei Medical University Fourth Hospital

Recruiting

Clinical Study of Breast Conserving Surgery Combined With Intraoperative Radiotherapy for Early Breast Cancer

Breast Cancer | HER2-negative Breast Cancer

China
Francesco De Cobelli
A.O. Ospedale Papa Giovanni XXIII; Cardarelli Hospital; AOU Pisana, Pisa, Italy

Not yet recruiting

Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological Therapy (PM-CARE)

Intrahepatic Cholangiocarcinoma

Italy
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Not yet recruiting

Study of ZG005 in Combination With Etoposide and Cisplatin in Participants With Advanced Neuroendocrine Carcinoma.

Neuroendocrine Carcinoma

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

An Phase III Study, Multicenter，Randomized Controlled Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma.

Bladder Cancer

China
Beijing Tiantan Hospital
West China Hospital; The First Affiliated Hospital of Zhengzhou University; Capital... and other collaborators

Recruiting

Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery

Glioma

China
Loma Linda University

Not yet recruiting

Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections

Surgical Site Infection

United States
Alexandria University

Recruiting

B-lynch Transverse Compression Suture

Blood Loss, Surgical

Egypt
Peking University Third Hospital

Recruiting

Microfracture With Platelet Rich Plasma Gel Injection for Ostechondral Lesion of the Talus

Platelet Rich Plasma | Osteochondral Lesion of Talus | Microfractures

China
Amgen

Recruiting

A Study Evaluating AMG 193 in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion

Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers

United States
Sun Jing

Not yet recruiting

A Clinical Study on the Efficacy and Safety of Paclitaxel Polymer Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma

Neoadjuvant Therapy | Locally Advanced Esophageal Squamous Cell Carcinoma
Shanghai Chest Hospital

Recruiting

Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan

Carcinoma | Non-small Cell Lung Cancer

China
University of Michigan Rogel Cancer Center

Not yet recruiting

Study of Neoadjuvant Enfortumab Vedotin and Pembrolizumab in Cisplatin-eligible Upper Tract Urothelial Cancer (NEPTUNE)

Urothelial Carcinoma

United States
The Affiliated Hospital of Qingdao University

Recruiting

Preoperative Neoadjuvant Immunotherapy Combined With Chemotherapy for Stage Ⅲ Unresectable Non-small Cell Lung Cancer (PILOT)

Non-small-cell Lung Cancer (NSCLC)

China
University Hospital, Montpellier

Not yet recruiting

Evaluation of the Absence of Intraoperative Bladder Catheterization in Case of Planned Cesarean Section (C2S)

Pregnant Women | Cesarean Section

France
Eduardo Schiffer
University Hospital, Geneva; Insel Gruppe AG, University Hospital Bern

Not yet recruiting

Platelet Count and Function After Usage of Two Different Cell Saver Devices During Liver Transplant Surgery (PLFLTS)

Liver Transplant | Hemorrhage, Surgical

Switzerland
Kliniken Essen-Mitte

Not yet recruiting

Association of Intraoperative Hemodynamic Characteristics to Postoperative Complications and Mortality (HeCoMo)

High-risk Surgery

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