Search clinical trials for: itraconazole

Total 396 results

Hospital de Clinicas de Porto Alegre

Unknown

Use Of Oral Itraconazole In Patients With Locally Limited Basocellular Carcinoma Of Skin.

Basal Cell Carcinoma | Hedgehog Pathway

Brazil
Celgene

Completed

Drug-drug Interaction Study of Ozanimod With Inhibitor or Inducer of CYP2C8 and/or CYP3A

Healthy Volunteer

United States
Bayer

Completed

Study to Learn More About the Effect of Itraconazole (ITZ) Given Repeatedly by Mouth on the Way How the Study Drug BAY1902607 Given One Time by Mouth Acts in the Human Body of Healthy Male Participants

Drug Interactions

Germany
Xian-Janssen Pharmaceutical Ltd.

Terminated

A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy

Hematologic Neoplasms

China
AstraZeneca

Completed

A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers

Heart Failure With Preserved Ejection Fraction (HFpEF)

United States
Jean Yuh Tang
National Cancer Institute (NCI)

Completed

Topical Itraconazole in Treating Patients With Basal Cell Cancer

Skin Basal Cell Carcinoma

United States
Cyclerion Therapeutics

Completed

A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

Healthy

United States
Boehringer Ingelheim

Completed

Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1026706 in Healthy Male Subjects

Healthy

Germany
Eli Lilly and Company

Completed

An Interaction Study of LY3200882 in Healthy Participants

Healthy

United States
Daiichi Sankyo, Inc.

Completed

Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy Participants

Pharmacokinetics

United States
Daiichi Sankyo, Inc.

Completed

A Study to Determine the Effects of Itraconazole on the Pharmacokinetics (PK) of DS-8500 in Healthy Subjects

Pharmacokinetics

United States
Guangxi Medical University
Guilin Medical College; Second Affiliated Hospital of Guangzhou Medical University and other collaborators

Unknown

Comparative Study of Human Immunodeficiency Virus Negative Host Talaromyces Between Voriconazole and Amphotericin Sequential Itraconazole Therapy (CSHHTVASIT)

Talaromyces in Human Immunodeficiency Virus Negative | To Compare Voriconazole and Amphotericin Sequential Itraconazole Therapy | To Dynamically Monitor the Anti-Interferon-γ Autoantibodies

China
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Phase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLC

Recurrent Non Small Cell Lung Cancer

United States, Singapore
Celgene

Completed

Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122

Healthy Volunteer

United States
Takeda

Completed

A Study to Evaluate the Effect of the Potent Cytochrome P-450 3A4 (CYP3A4) Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-954 in Healthy Adult Participants

Healthy Participants

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of the Potent CYP3A4 Inhibitor Itraconazole on the Pharmacokinetics (PK) of TAK-906 in Healthy Participants

Healthy Participants

United States
Millennium Pharmaceuticals, Inc.

Completed

Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors

Advanced Solid Tumors

United States
Stanford University

Completed

Pilot Biomarker Trial to Evaluate the Efficacy of Itraconazole in Patients w/ Basal Cell Carcinomas

Skin Cancer | Basal Cell Carcinoma (BCC)

United States
Mayne Pharma International Pty Ltd

Completed

Bioavailability Study of Lozanoc™ 65 mg Itraconazole Capsules in Patients Requiring Prophylaxis

Neutropenia

Australia
Mayne Pharma International Pty Ltd

Completed

Steady-State Comparative Bioavailability Study in Prophylaxis Patients of Lozanoc® 50 mg With Sporanox® 100 mg

Neutropenia

Australia
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

A Randomized Phase II Study of SUBATM-itraconazole in Patients With Untreated Squamous NSCLC. (NA_00067809)

Non-small Cell Lung Cancer Metastatic

United States
Nerre Therapeutics Ltd.

Completed

A Pharmacokinetic Study of the Effect of Itraconazole Exposure to Orvepitant in Healthy Volunteers

Pharmacokinetic Study in Healthy Male Volunteers

United Kingdom
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Risdiplam (RO7034067) Given by Mouth in Healthy Volunteers

Spinal Muscular Atrophy

Netherlands
Merck Sharp & Dohme LLC

Completed

Single and Multiple Dose Study of Uprifosbuvir (MK-3682/IDX21437) in Healthy and Hepatitis C Virus (HCV)-Infected Participants (MK-3682-001)

Chronic Hepatitis C
Ain Shams University

Unknown

Itraconazole in Non Small Cell Lung Cancer

Lung Cancer

Egypt
GlaxoSmithKline

Completed

Prospective Sexual Function Study for BPH Subjects

Prostatic Hyperplasia

Germany, Australia, Netherlands, Spain, Hungary, France, Greece
Fujian Medical University

Unknown

Posaconazole vs Itraconazole in Preventing IFD Post-HSCT

IFD Post-HSCT

China
Bayer
Orion Corporation, Orion Pharma

Completed

Drug-drug Interaction (DDI) Study to Assess ODM-201 as a Victim of CYP3A4 Inhibition or Induction

Biological Availability

Germany
Pulmatrix Inc.

Completed

Safety, Tolerability and Pharmacokinetics of PUR1900 (Itraconazole Powder) in Healthy Volunteers and Adults With Asthma

Asthma

United Kingdom
Boehringer Ingelheim

Completed

This Study in Healthy Men Tests How Itraconazole Influences the Amount of BI 1015550 in the Blood

Healthy

Germany
Galapagos NV

Completed

A Study in Healthy Male Volunteers to Look at How the Test Medicine GLPG1690 is Taken up by the Body When Doses of Itraconazole and Voriconazole Are Given to Healthy Volunteers

Healthy

United Kingdom
Mereo BioPharma

Completed

The Effect of Itraconazole on BCT197 Exposure in Healthy Male Participants

Interaction

United States
Bayer

Terminated

Single Ascending Dose, First-in-Human Study on Safety, Tolerability and Pharmacokinetics of BAY1161116

Polycystic Ovary Syndrome

Germany
Postgraduate Institute of Medical Education and...

Unknown

Isotretinoin In Preventing Recurrences In Chronic Recurrent Dermatophytosis (ISORD)

Tinea
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects

Malignancies Multiple

United States
AstraZeneca

Completed

A Phase I Study to Assess PK of AZD7986 Alone & With Verapamil, Itraconazole or Diltiazem in Healthy Subjects

Healthy Subjects

United Kingdom
Corcept Therapeutics

Completed

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Healthy | Drug Interaction Potentiation

United States
Hoffmann-La Roche

Completed

A Study to Evaluate the Effect of a Potent Cytochrome P450 (CYP) 3A Inhibitor on Ipatasertib

Healthy Volunteers

United States
Pfizer

Completed

A Study To Estimate The Effects Of Itraconazole On Pharmacokinetics Of Pf-06649751 In Healthy Adult Subjects

Healthy

Belgium
Debiopharm International SA

Completed

A Study to Investigate the Effect of Itraconazole on the Pharmacokinetics of Debio 1450 in Healthy Subjects

Healthy Participants

United Kingdom
Johns Hopkins University
Memorial Sloan Kettering Cancer Center

Completed

A Two-dose Level Clinical Trial of Itraconazole in Patients With Metastatic Prostate Cancer Who Have Had Disease Progression While on Hormonal Therapy

Prostate Cancer

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of Fluconazole and Itraconazole on Erdafitinib Pharmacokinetics in Healthy Adult Participants

Healthy

Belgium
Bayer

Completed

First in Human Study to Investigate the Safety and Tolerability, Pharmacokinetics, Itraconazole Drug-drug-interaction and Food Effect of BAY1817080

Clinical Trials, Phase I as Topic

Germany
Novartis Pharmaceuticals

Completed

PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2)

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
GlaxoSmithKline

Completed

Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjects

Infections, Bacterial

United States
Janssen Cilag N.V./S.A.

Completed

Study to Investigate Effects of Repeated Administration of Itraconazole on Pharmacokinetics of JNJ-42847922 in Healthy Male Participants

Healthy

Germany
Agios Pharmaceuticals, Inc.

Completed

Drug-Drug Interaction Study of AG120 in Healthy Subjects

Healthy

United States
Pfizer

Withdrawn

An Open-label, Two-period, Fixed-sequence Study to Evaluate Multiple-dose Itraconazole Effect on The Single-dose PK of PF-06372865 in Healthy Subjects

Healthy

United States
Boehringer Ingelheim

Completed

Drug-drug Interaction (DDI) With a P-gp Inhibitor, Organic Anion Transporting Polypeptide OATP-inhibitor, Food Effect

Healthy

Germany
Assiut University

Unknown

Antifungal Drugs in Treatment of Onychomycosis

Antifungal Drugs in Onychomycosis

3

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