Search clinical trials for: medication safety

Total 47914 results

University of Florence
Azienda Ospedaliera Città della Salute e della Scienza di Torino; University... and other collaborators

Recruiting

Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients (STAR)

Migraine | Chronic Migraine | Migraine Without Aura | Migraine With Aura

Italy
University of Massachusetts, Worcester
National Institute on Aging (NIA); Harvard Pilgrim Health Care; Humana Healthcare... and other collaborators

Not yet recruiting

A Program to Reduce Inappropriate Medications Among Older Adults With Alzheimer's Disease: Implementation Phase 2 (DPRESCRIBE-AD2)

Alzheimer Disease

United States
University of Beykent

Not yet recruiting

Evaluation of Nursing Students' Crisis Management Skills in Medication Safety Simulation (RCS)

Nurse
AstraZeneca

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Asian Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension (BaxAsia)

Resistant Hypertension | Uncontrolled Hypertension

Argentina, China, Korea, Republic of, Vietnam, Japan, Philippines, Hong Kong, Turkey, India, Australia, Russian Federation
New York Presbyterian Hospital

Not yet recruiting

Evaluations of CDS Systems

Safety Issues
Hospices Civils de Lyon

Not yet recruiting

PACOME (PAtient Cancer Oral MEdication) Cohort of Patients Treated With Oral Anticancer Drugs Benefiting From Oncoral Multidisciplinary Monitoring in Real Life: Predictive Factors and Safety of Treatments (PACOME)

Cancer | Oncology | Oncoral Program

France
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

Taiwan, United States, Spain, Argentina, China, Italy, Australia, France, Canada, Japan, Belgium, Denmark, Germany, Hungary, Israel, Austria, Korea, Republic of, Brazil, Mexico, Netherlands, Romania, United Kingdom, Greece, Czechia, India, Slovak... and more
The University of Hong Kong
Hong Kong Jockey Club Charities Trust; Lok Sin Tong Benevolent Society, Kowloon and other collaborators

Recruiting

Evaluation of Medication Management Service

Hypertension | Diabetes Mellitus, Type 2 | Medication Adherence | Polypharmacy | Medication Safety | High Risk Medications

Hong Kong
Yonsei University

Not yet recruiting

Clinical Trial for Non-inferiority and Safety of Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in Patients With Hematologic Malignancies Who Require Prophylactic Hepatitis B Antiviral Treatment

Patients With Malignant Blood Disease Requiring Hepatitis B Antiviral Medication
AstraZeneca

Recruiting

A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension (BaxHTN)

Resistant Hypertension | Uncontrolled Hypertension

United States, Canada, Italy, South Africa, Korea, Republic of, Australia, Belgium, France, Germany, Poland, Japan, Spain, Vietnam, Argentina, Bulgaria, Turkey, India, Malaysia, Taiwan, Thailand, Austria, Israel, Netherlands, Sweden, United... and more
University of California, San Francisco
UCSF CAPS-HIV Innovative Grant; UCSF CFAR-ARI HIV Boost Award; ACC/ABC Merck...

Recruiting

Heart Failure Polypill at a Safety Net Hospital

HIV Infections | Heart Failure With Reduced Ejection Fraction

United States
Akros Pharma Inc.
ICON Clinical Research

Recruiting

Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction (POWER-HF)

Chronic Heart Failure

United States
Shin Kong Wu Ho-Su Memorial Hospital
National Taipei University of Nursing and Health Sciences

Recruiting

The Effectiveness of a Chatbot-facilitated High Alert Medication Education for 2-year Post Graduate Nurses

Education, Nursing

Taiwan
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety and Effectiveness of Trastuzumab Emtansine (T-DM1) as Therapy in Chinese Participants With HER2 Positive Advanced Breast Cancer

Breast Cancer

China
The University of Texas at Arlington
Agency for Healthcare Research and Quality (AHRQ)

Recruiting

Partnership in Resilience for Medication Safety (PROMIS) (PROMIS)

Patient Engagement | Patient Empowerment | Patient Activation

United States
University College, London
University College London Hospitals; Barts & The London NHS Trust; British Heart...

Recruiting

Safety of Withdrawal of Pharmacological Treatment for Recovered HER2 Targeted Therapy Related Cardiac Dysfunction (HER-SAFE)

Heart Failure | HER2-positive Breast Cancer | Cardiotoxicity | Cancer, Therapy-Related

United Kingdom
Ludwig-Maximilians - University of Munich
University Hospital Heidelberg; University of Witten/Herdecke; University Hospital... and other collaborators

Recruiting

Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy (PARTNER)

Antipsychotic Agents | Antidepressive Agents | Analgesics, Opioid | Deprescriptions | Hypnotics and Sedatives | Cholinergic Antagonists

Germany
Pulnovo Medical (Wuxi) Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Recruiting

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure (PADN-HF-PH)

Cardiovascular Diseases | Vascular Diseases | Heart Failure | Hypertension | Pulmonary Hypertension | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Heart Failure With Mid Range Ejection Fraction

China
University of Wisconsin, Madison
Agency for Healthcare Research and Quality (AHRQ)

Recruiting

Meds@HOME App to Support Medication Safety

Medication Errors and Other Product Use Errors and Issues

United States
Novartis Pharmaceuticals

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of QVM149 (Indacaterol Acetate / Glycopyrronium Bromide / Mometasone Furoate) Versus Salmeterol Xinafoate/Fluticasone Propionate in Children From 12 Years to Less Than 18 Years of Age With Asthma.

Asthma
Shanghai Huihe Medical Technology Co., Ltd

Not yet recruiting

A Prospective, Multicenter, Randomized Controlled Trial to Evaluate the Efficacy and Safety of the Transcatheter Tricuspid Valvuloplasty System in Patients With Severe or Above Tricuspid Regurgitation

Tricuspid Regurgitation
University of Colorado, Denver
Agency for Healthcare Research and Quality (AHRQ)

Recruiting

Pediatric Medication Therapy Management Trial (pMTM)

Child, Only | Medication Compliance | Medication Administered in Error | Disabilities Multiple | Medication Interaction

United States
Chiesi Hungary Ltd.
Chiesi Slovenija, d.o.o.

Recruiting

Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients (LTA)

Liver Failure

Hungary, Slovenia
University of Michigan
Patient-Centered Outcomes Research Institute

Recruiting

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial (CARES)

Pain, Postoperative | Surgery

United States, Canada
Taichung Veterans General Hospital
Institute of Adherence to Medication

Recruiting

Tenofovir Alafenamide Switch Therapy in Chronic Hepatitis B

Patient Satisfaction | Safety Issues | Efficacy, Self | Drug Adherence

Taiwan
University Hospital, Angers

Not yet recruiting

Impact of Simulation-Based Training on the Safety of Medication Administration (SIM-SAM)

Simulation | Health Knowledge, Attitudes, Practice | Nurse Training

France
Biogen

Recruiting

A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) and/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy (AMETHYST)

Subacute Cutaneous Lupus Erythematosus | Chronic Cutaneous Lupus Erythematosus

United States, Italy, Korea, Republic of, Taiwan, Argentina, Chile, Spain, Canada, Serbia, France, Germany, Japan, Brazil, United Kingdom, Bulgaria, Portugal, Switzerland, Philippines, Saudi Arabia, Sweden, Mexico, Poland, Hungary, Puerto... and more
University of Sharjah

Not yet recruiting

Pharmacists Interventions on Patients Diabetic, and Obese Patients in the UAE: Randomized Controlled Trials.

Hypertension | Obesity | Pharmacist-Patient Relations | Diabete Type 2
Taichung Veterans General Hospital
Institute of Adherence to Medication

Recruiting

Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection

Safety Issues

Taiwan
National Cancer Institute (NCI)

Recruiting

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Malignant Solid Neoplasm

United States
Celon Pharma SA
National Center for Research and Development, Poland

Recruiting

Efficacy, Safety and Pharmacokinetic Study of CPL500036 in Patients With Levodopa Induced Dyskinesia

Parkinson Disease | Dyskinesia, Medication-Induced

Poland, Ukraine
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial Serous Adenocarcinoma | Uterine Corpus Carcinosarcoma

United States, Puerto Rico
Universidad Miguel Hernandez de Elche
Fundación Pública Andaluza Progreso y Salud; Servicio Aragonés de Salud (SALUD) and other collaborators

Not yet recruiting

Safe Use of Medication at Home by Caregivers. Experimental Study

Caregivers of Multi-pathological and Polypharmacy Adults
Visualiza
Seva Foundation

Not yet recruiting

Safety and Effectiveness of Drop-free Small Incision Cataract Surgery

Ocular Hypertension | Ocular Inflammation | Cataract | Post-Op Complication
BioGaia Pharma AB
BioFortis

Recruiting

Safety and Preliminary Efficacy of BGP345A in Constipation Due to Opioid-based Medications (OIC1)

Opioid-Induced Constipation

France
AstraZeneca
Daiichi Sankyo

Recruiting

A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations

Locally Advanced or Metastatic Non-Small Cell Lung Cancer

China, Korea, Republic of, Germany, Italy, Poland, Belgium, Mexico, Turkey, Spain, France, United States, Canada, Taiwan, Brazil, Austria, Hong Kong, India, Japan, Netherlands, Denmark
Sure Med Compliance
National Institute on Drug Abuse (NIDA)

Recruiting

Comparing a Patient Self-Assessment Software to Treatment as Usual in Opioid Prescriber and Patient Opioid Outcomes

Chronic Pain | Opioid Use | Opioid-use Disorder | Opioid Misuse

United States
Biogen

Recruiting

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus (TOPAZ-1)

Lupus Erythematosus, Systemic

United States, Australia, Korea, Republic of, Chile, Spain, Poland, Philippines, Taiwan, Greece, Brazil, Bulgaria, Mexico, France, Russian Federation, Sweden
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy (Astefania)

Breast Cancer

Korea, Republic of, United States, Australia, China, Ukraine, Spain, United Kingdom, Turkey, Mexico, Brazil, Austria, Belgium, Denmark, Germany, Greece, Russian Federation, Taiwan, France, Kenya, New Zealand, Portugal, Thailand, Rom... and more
Binghamton University
State University of New York - Upstate Medical University

Not yet recruiting

Evaluating the Impact of a Safe Medication Storage Device

Poisoning | Safety Issues | Accidents Injury
University of Iowa
Centers for Disease Control and Prevention

Recruiting

Medication Empowerment and Deprescription for Safety (MEDS) Study (MEDS)

Aging | Fall Injury

United States
University of British Columbia
Canadian Institutes of Health Research (CIHR); Vancouver Coastal Health; Ministry...

Not yet recruiting

Evaluating ActionADE on Adverse Drug Event Due to Non-Adherence

Adverse Drug Event | Non-Adherence, Medication
Takeda

Recruiting

Dose-Ranging Study of the Efficacy and Safety of TAK-101 for Prevention of Gluten-Specific T Cell Activation in Participants With Celiac Disease on a Gluten-Free Diet

Celiac Disease

United States, Australia, Canada, New Zealand
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Seagen Inc.

Recruiting

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC... and other conditions

United States, Canada, Puerto Rico
Karen C. Nanji,M.D.,M.P.H.
University of California, San Francisco; University of Toronto; University of... and other collaborators

Not yet recruiting

Perioperative Recommendations for Medication Safety

Perioperative Medication Safety
University of Illinois at Chicago
National Institute of Mental Health (NIMH); Emory University; University of Mississippi... and other collaborators

Recruiting

An Avatar-based Mobile Phone Intervention to Promote Health in African American MSM

Medication Adherence | Retention in Care

United States
University of Saskatchewan

Recruiting

Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery (RUMBLE)

Laparoscopic Surgery | Analgesia | Colorectal Surgery | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Postoperative Ileus | Analgesics, Opioid | Lidocaine | Opioid Free Anesthesia

Canada
Centre Hospitalier Universitaire de Nīmes

Recruiting

Impact of Mulstidisciplinary Medication Assessment Review in Surgery Departments (CHIROPMEV)

Chronic Disease

France
University Health Network, Toronto

Not yet recruiting

Targeted Deprescribing in Patients on Hemodialysis

End Stage Renal Disease on Dialysis (Diagnosis)

Canada
Boston Medical Center
Boston University; Eunice Kennedy Shriver National Institute of Child Health... and other collaborators

Recruiting

MOM NEST Study: Maternal Opioid Medication: Naltrexone Efficacy Study

Pregnancy, High Risk | Alcohol Use Disorder | Opioid-use Disorder | Neonatal Abstinence Syndrome

United States

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