Search clinical trials for: mitochondrial DNA depletion syndrome

Total 45021 results

Celgene Corporation

Completed

A Phase II, Parallel Group, Randomized, Placebo-Controlled Study of the Safety and Efficacy of Thalidomide in Reducing Weight Loss in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Cidofovir in the Treatment of Venereal Warts in HIV-Infected Patients

HIV Infections | Condyloma Acuminata

United States
National Center for Research Resources (NCRR)
Yale University

Completed

Phase II Pilot Study of Octreotide, a Somatostatin Octapeptide Analog, for Gastrointestinal Hemorrhage in Hormone-Refractory Hereditary Hemorrhagic Telangiectasia and Senile Ectasia

Hereditary Hemorrhagic Telangiectasia | Ectasia
Research Institute for Genetic and Human Therapy

Completed

Safety and Effectiveness of Combining Hydroxyurea (HU) With Didanosine (ddI) and Stavudine (d4T) for Treatment of HIV-Infected Adults

HIV Infections

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Safety, Pilot Pharmacokinetics and Neurocognitive Study of AS-101 in Combination With Zidovudine in AIDS/ARC Patients

HIV Infections

United States
Immunobiology Research Institute

Completed

Double Blind Study of Thymopentin Effects on Patients With HIV-1 Infection

HIV Infections

United States
Fisons

Completed

A Double-Blind Placebo-Controlled Group Comparative Study To Evaluate the Safety and Effectiveness of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in Patients With AIDS Post First Episode PCP

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Argus Pharmaceuticals

Completed

A Phase I/II Clinical Study of Nystatin I.V. (Intravenous) in Patients With HIV Infection.

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Two Anti-HIV Drug Combinations

HIV Infections

United States, Puerto Rico
Hoffmann-La Roche

Completed

An Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of Dideoxycytidine (ddC) in Patients With AIDS or Advanced ARC Who Previously Demonstrated Intolerance to Zidovudine (AZT) in Protocol N3300 or N3492

HIV Infections

United States
HEM Research

Completed

A Multicenter, Double-Blind, Controlled Study to Evaluate Ampligen

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Retrovir in the Treatment of Psoriasis in HIV-Positive Patients

HIV Infections | Psoriasis

United States
Alkermes, Inc.

Completed

The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Glaxo Wellcome

Completed

A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
LyphoMed

Completed

A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral / Oral Trimethoprim - Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia in AIDS

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Janssen, LP

Completed

Study of Itraconazole in Patients With Advanced HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 141W94 in Combination With Other Anti-HIV Drugs

HIV Infections

United States
Aronex Pharmaceuticals

Completed

Safety and Effectiveness of Zintevir (AR177) Given to HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles; National Institute of Neurological Disorders...

Completed

Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment

Epilepsy | Spasms, Infantile
Pharmacia and Upjohn

Completed

Safety, Tolerance, Efficacy and Pharmacokinetics of Multiple Doses of sCD4-PE40 in the Treatment of HIV-Infected Individuals

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3

HIV Infections | Sarcoma, Kaposi

United States
Agouron Pharmaceuticals

Suspended

Effectiveness of a New Anti-HIV Drug (AG1549) Plus Viracept (Nelfinavir) Plus Combivir (Zidovudine/Lamivudine) in HIV-Infected Patients

HIV Infections

United States, Canada, Puerto Rico, Dominican Republic
Glaxo Wellcome

Completed

A Phase III Randomized Double-Blind, Multicenter Study to Evaluate the Safety and Efficacy of 3TC/ZDV/1592U89 and 3TC/ZDV/IDV in HIV-1 Infected Antiretroviral Therapy-Naive Subjects.

HIV Infections

United States
RespireRx
FRAXA Research Foundation

Completed

Effects of CX516 on Functioning in Fragile X Syndrome and Autism

Fragile X Syndrome | Autism

United States
National Institute of Neurological Disorders and...
Mayo Clinic

Unknown

Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone

Acute Disseminated Encephalomyelitis | Devic's Syndrome | Marburg's Variant of Multiple Sclerosis | Balo's Concentric Sclerosis | Acute Transverse Myelitis
National Institute of Allergy and Infectious Diseases...

Completed

Heterosexual HIV Transmission Study (HATS). Prospective Cohort Study

HIV Infections

United States
United Biomedical

Completed

A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Immunotherapeutic P3C541b in HIV-1 Seropositive Human Subjects

HIV Infections

United States
United Biomedical

Completed

A Phase I/II Safety and Immunogenicity Trial of UBI Microparticulate Monovalent (HIV-1 MN) Branched Peptide Vaccine in HIV-1 Seronegative Human Subjects

HIV Infections

United States
Janssen, LP

Completed

A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients

HIV Infections | Histoplasmosis

United States
University of California, San Francisco

Completed

Evaluation of the Epidermal Langerhans Cell Population in AIDS / ARC Patients by the Topical Application of a Potent Contact Allergen (1-Chloro-2,4-Dinitro-Chlorobenzene) (DNCB)

HIV Infections

United States
Pfizer

Completed

A Study to Evaluate the Safety and Efficacy of Azithromycin in Individual Patients With Serious Nontuberculous Mycobacterial Disease Who Are Failing or Intolerant of Other Available Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
National Center for Research Resources (NCRR)
Children's Hospital of Philadelphia

Completed

Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major

Osteoporosis | Osteopenia | Thalassemia Major
Agouron Pharmaceuticals

Completed

Phase I Study of Safety, Tolerability, and Pharmacokinetics of Viracept in HIV-1 Infected Children and Exposed Infants

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs

HIV Infections

United States
Northwestern University

Completed

A Randomized, Placebo-Controlled Study of the Safety and Efficacy of Efavirenz, Didanosine, and Stavudine in Combination With or Without Hydroxyurea in Antiretroviral Naive or Experienced HIV-Infected Patients

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...
National Institute of Nursing Research (NINR)

Completed

HIV Symptom Management Program for African American Mothers

HIV Infections

United States
G D Searle
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I Rising Dose Tolerability Study of SC-48334 in Patients With Acquired Immunodeficiency Syndrome (AIDS) and Advanced AIDS Related Complex

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Exploratory Study to Evaluate the Effects of Antiretroviral Cessation on Plasma Associated HIV-1 RNA

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Study of Women Who Have AIDS

HIV Infections

United States
Glaxo Wellcome

Completed

The Antiviral Efficacy of Concurrent Zidovudine and 2',3'-Dideoxyinosine or 2',3'-Dideoxycytidine in Patients With Human Immunodeficiency Virus Disease

HIV Infections

United States, Puerto Rico, Australia
Lederle Laboratories

Completed

Phase II Study of Novantrone(R) (Mitoxantrone) and Etoposide in Patients With HIV Associated Large Cell and Immunoblastic Lymphomas

HIV Infections | Lymphoma, Non-Hodgkin

United States
Mallinckrodt

Completed

The Therakos UVAR Photopheresis System in the Treatment of AIDS-Related Complex

HIV Infections

United States
Interferon Sciences

Completed

Double-Blind, Randomized, Dose Ranging Study of Alferon LDO (Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived)) in HIV+ Subjects

HIV Infections

United States
Glaxo Wellcome

Completed

Retrovir Capsules in the Treatment of HIV-Infected Patients in Renal Failure

HIV Infections | Kidney Failure, Chronic

United States
Fisons

Completed

A Double-Blind Group Comparative Study To Evaluate the Long-Term Safety and Effectiveness of Two Different Doses of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients With Multiple Episodes of PCP

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Hoffmann-La Roche

Completed

Open-Label Program of Dideoxycytidine ( ddC ) to Be Used in Combination With Zidovudine ( AZT ) for Treatment of Advanced HIV Disease

HIV Infections

United States
Pharmacia and Upjohn

Completed

Prospective Open-Label Study of the Emergence of Drug Resistance in Patients Infected With HIV-1 Who Are Taking Oral U-87201E

HIV Infections

United States
Oxo Chemie GmbH

Completed

A Phase I/II Clinical Study of WF 10 IV Solution ( TCDO ) in Patients With HIV Infection

HIV Infections

United States
Burroughs Wellcome

Completed

A Phase I Trial to Evaluate the Safety and Pharmacokinetics of 1592U89

HIV Infections

United States

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