Search clinical trials for: morbidity and mortality of patients with acute cholecystitis, early surgery versus conservative ther

Total 490172 results

Heidelberg University
Bayer

Completed

Acute Cholecystitis - Early Laparoscopic Surgery Versus Antibiotic Therapy and Delayed Elective Cholecystectomy (ACDC)

Acute Cholecystitis

Germany
Niguarda Hospital
Italian Society of Cardiology

Completed

Early Aggressive Versus Initially Conservative Therapy in Elderly Patients With Non-ST-Elevation Acute Coronary Syndrome

Acute Coronary Syndrome

Italy
GlaxoSmithKline

Completed

Clinical Progression and Costs in Benign Prostatic Hyperplasia Patients Treated With Early Versus Delayed Combination Therapy

Benign Prostatic Hyperplasia
NHS National Waiting Times Centre Board
University of Glasgow

Completed

Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients With Non ST Elevation Elevation Acute Coronary Syndrome (CABG-ACS)

Unstable Angina | Non ST Elevation Myocardial Infarction

United Kingdom
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Impact on Mortality of a Strategy Including Continuous Positive Airway Pressure Plus High Flow Nasal Cannula Oxygen Therapy Versus High Flow Nasal Cannula Oxygen Therapy Alone in Patients With de Novo Acute Hypoxemic Respiratory Failure: a Prospective, Randomized Controlled Trial. (HighCPAP)

De Novo Hypoxemic Acute Respiratory Failure (hARF)
Assistance Publique - Hôpitaux de Paris
Fonds de Dotation ACTION

Not yet recruiting

Assessment of an Early De-Escalation to a Low-potency Single Antiplatelet Therapy Guided by Genetics Versus a Systematic High-Potency Single Antiplatelet Therapy to Neutralize Bleeding Complications in Patients With High Bleeding Risk Beyond One Month After an Acute Coronary Syndrome (ADEN)

MYOCARDIAL INFARCTION

France
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Melanoma | Sarcoma | Acute Myeloid Leukemia | Stage I Uterine Corpus Cancer AJCC v7 | Stage II Uterine Corpus Cancer AJCC v7 | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Stage III Pancreatic... and other conditions

United States
Central Hospital, Nancy, France

Not yet recruiting

Effect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic Shock (LevoHeartShock)

Cardiogenic Shock

France
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia With PML-RARA | t(15;17)

United States, Puerto Rico
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor (RAPID CABG)

Acute Coronary Syndrome

Canada
Cairo University
Misr International University

Completed

Comparison of Weekly Versus Every Three Weeks of Carboplatin Plus Paclitaxel in Patients With Advanced Epithelial Ovarian Cancer

Advanced Epithelial Ovarian Cancer

Egypt
Michael E Villarreal, MD
Merck Sharp & Dohme LLC

Terminated

Comparing the Effectiveness of IV Bezlotoxumab Versus Placebo in Decreasing Morbidity and Mortality in Patients With Fulminant C. Diff Requiring Surgery.

Clostridia Difficile Colitis | Clostridium; Sepsis

United States
Baskent University

Active, not recruiting

Postoperative Morbidity / Mortality Rates of Patients With Pulmonary Hypertension (PulmonaryHT)

oPAP Should be > 25mmHg in Right Heart Catheterization at Rest | There Should be Patients Who Will Undergo Non-cardiac and Non-obstetric Surgery

Turkey
Onze Lieve Vrouwe Gasthuis
ZonMw: The Netherlands Organisation for Health Research and Development; Stichting...

Completed

Early Surgery Versus Conservative Therapy for Meniscal Injuries in Older Patients (ESCAPE)

Meniscal Tear

Netherlands
Galderma R&D

Completed

Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp

Actinic Keratosis

United States
University Hospital, Clermont-Ferrand

Completed

Hemostasis Evolution During Fluid Loading in Abdominal Surgery. Effects of Fluid Choice: Saline Versus Hydroxyethyl Starch (HAEMO Study) (HAEMO)

Postoperative Mortality | Postoperative Morbidity | Hemostasis Change

France
University Hospital, Clermont-Ferrand
Agence Nationale de sécurité du Médicament; Programme Hospitalier de Recherche... and other collaborators

Completed

Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study) (FLASH)

Postoperative Mortality | Postoperative Morbidity

France
Institute of Liver and Biliary Sciences, India

Unknown

Early Versus Late CRRT in ACLF Patients With Septic Shock and AKI

Septic Shock and Acute Kidney Injury

India
Ondrej Ryska

Unknown

Early Surgery Versus Conservative Treatment in Patients With Ileocaecal Crohn's Disease (ESPRIT)

Crohn's Disease

Czech Republic
Memorial Sloan Kettering Cancer Center
Genentech, Inc.; Weill Medical College of Cornell University

Completed

Pre-operative Chemotherapy Plus Bevacizumab With Early Salvage Therapy Based on PET Assessment of Response in Patients With Locally Advanced But Resectable Gastric and GEJ Adenocarcinoma

Gastric Cancer | Esophageal Cancer

United States
The Facial Surgery Research Foundation

Unknown

Neck Surgery in Treating Patients With Early-Stage Oral Cancer

Head and Neck Cancer

United Kingdom
University of Florida

Completed

Early Invasive Versus Conservative Therapy in Women With an Acute Coronary Syndrome (Lady Gator)

Acute Coronary Syndrome
Novartis Pharmaceuticals

Completed

Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure (ASTRONAUT)

Acute Decompensated Heart Failure | Congestive Heart Failure

Colombia, Czech Republic, India, Italy, Belgium, Turkey, Argentina, France, Germany, Israel, Spain, Canada, Taiwan, United States, Singapore, Russian Federation, Philippines, Slovakia, Sweden, Hungary, Finland, Poland, Romania, Brazil
St. Bartholomew's Hospital

Unknown

Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease

Myelodysplastic Syndromes | Leukemia | Infection | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
Roswell Park Cancer Institute

Completed

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Neuroblastoma | Graft Versus Host Disease

United States
University of Belgrade

Unknown

Laparotomy Versus Percutaneous Puncture in Patients With Abdominal Compartment Syndrome During Acute Pancreatitis (DECOMPRESS)

Mortality | Acute Pancreatitis

Serbia
Centre Hospitalier Universitaire Vaudois

Completed

Referral Patterns for Hospital Acquired Acute Kidney Injury and Relevance to Renal Outcomes (HA-AKI)

Mortality | Renal Replacement Therapy

Switzerland
Technische Universität Dresden

Completed

AML2003 - Standard-Therapy vs Intensified Therapy for Adult Acute Myeloid Leukemia Patients <= 60 Years

Leukemia, Nonlymphocytic, Acute

Germany
Chen Xiaoping

Recruiting

Comparing the Prognosis of Patients With HCC and PVTT Treated With Surgery Versus Locoregional Therapy.

Hepatocellular Carcinoma

China
Yonsei University

Not yet recruiting

Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial)

Peripheral Artery Disease | Polyvascular Disease

Korea, Republic of
Abbott

Recruiting

Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia

Functional Dyspepsia

Malaysia, Armenia
Assiut University

Not yet recruiting

Relation of Laboratory Indices to Left Ventricular Thrombus Formation in Patients With Acute Anterior ST Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention or Thrombolytic Therapy

Left Ventricular Thrombus
Second Affiliated Hospital, School of Medicine,...

Recruiting

Early Versus Late Initiation of Anticoagulation in Mild-to-moderate AIS Patients With NVAF (ASAP)

Atrial Fibrillation | Acute Ischemic Stroke

China
60P Australia Pty Ltd

Not yet recruiting

A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression

Infectious Disease | SARS-CoV-2 | Severe Acute Respiratory Syndrome Coronavirus 2 | COVID 19 Disease | Mild to Moderate COVID 19 Disease
Asian Institute of Gastroenterology, India

Recruiting

Urgent (<24 Hours) Versus Early (24 to 48 Hours) ERCP for Patients With Mild and Moderate Acute Cholangitis

Acute Cholangitis

India
Ahram Canadian University

Recruiting

Mat Pilates Versus General Exercises for Patients With Nonspecific Acute Low Back Pain

Low Back Pain

Egypt
Heart Initiative

Recruiting

Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure (CORTAHF)

Acute Heart Failure

Armenia
RapidPulse, Inc

Not yet recruiting

Early Feasibility Study of RapidPulseTM Aspiration System for Patients With Acute Ischemic Stroke (PULSE-C)

Stroke | Acute Ischemic Stroke | Large Vessel Occlusion | Mechanical Thrombectomy

Georgia
Xiangya Hospital of Central South University
Jiangsu Simcere Pharmaceutical Co., Ltd.

Not yet recruiting

Effect of Early Versus Late Initiation of Edaravone Dexborneol on Neural Function in Patients With Acute Ischemic Stroke (EARLYS)

Ischemic Stroke, Acute | Treatment Outcome

China
Campus Bio-Medico University

Recruiting

Quality of Life After Conservative Oncoplastic Surgery in Breast Cancer Patients (IRONY: lIfe afteR ONcoplastic surgerY) (IRONY)

Breast Cancer

Italy
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Recruiting

Cilostazol Dexborneol Versus Placebo for Microcirculation Dysfunction After Reperfusion Therapy in Patients With Acute Ischemic Stroke With Large Vessel Occlusion (CRYSTAL)

Acute Ischemic Stroke | Large Vessel Occlusion | Reperfusion

China
Gilead Sciences
Alliance Foundation Trials, LLC.; NSABP Foundation Inc

Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/NSABP B-63) (ASCENT-05)

Triple Negative Breast Cancer

United States
National Cancer Institute (NCI)

Not yet recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia
Sven Löffeler
Oslo University Hospital; Klinbeforsk

Recruiting

Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer (GrandP/SPCG19)

Prostate Cancer

Norway, Denmark, Finland
Yonsei University

Recruiting

DCS Versus DES for One-month DAPT in Patients With ACS: ONE-PASS Trial (ONE-PASS)

Acute Coronary Syndrome

Korea, Republic of
Nantes University Hospital
Roche Pharma AG; BioMérieux; ThermoFisher Scientific Brahms Biomarkers France; ...

Recruiting

Development of an Innovative Clinico-biological Score for the Early Detection of Acute Renal Failure Associated With Cardiac Surgery. (DETECT-AKI)

Acute Kidney Injury

France
Assiut University

Not yet recruiting

Serum Cysteine Rich Protein 61 and Cystatin C for Early Detection of Acute Kidney Injury in Patients With Heart Diseases

Acute Kidney Injury
Pomeranian Medical University Szczecin

Not yet recruiting

Early-initiated High Flow Oxygen Therapy vs Conventional Oxygen Therapy Among Patients With ARDS in the Course of SARS-CoV2 Pneumonia.

Oxygen Deficiency | Corona Virus Infection | ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2

Poland
Hepatopancreatobiliary Surgery Institute of Gansu...
The First Affiliated Hospital of Anhui Medical University; Xiangya Hospital... and other collaborators

Recruiting

Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106)

Hepatic Encephalopathy | Cirrhosis

China

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