Search clinical trials for: multicenter randomized controlled trial

Total 49560 results

China Stroke Databank Center
The First Affiliated Hospital with Nanjing Medical University; Wuhan University and other collaborators

Recruiting

Time Window for Ischemic Stroke First Mobilization Effectiveness (TIME)

Brain Ischemia | Stroke Rehabilitation

China
Université de Sherbrooke
Ferring Pharmaceuticals; Centre de recherche du Centre hospitalier universitaire...

Recruiting

Fit-for-Fertility Multicenter Randomized Controlled Trial (FFF)

Obesity | Infertility, Female

Canada
Centre Hospitalier Universitaire Dijon

Recruiting

MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled Trial (METOGiA)

Giant Cell Arteritis

France
Jewish General Hospital
University of Manitoba; McGill University Health Centre/Research Institute... and other collaborators

Recruiting

Impact of a Patient-Centered Program for Low Anterior Resection Syndrome A Multicenter Randomized Controlled Trial

Low Anterior Resection Syndrome | Rectal Cancer | Surgery | Patient Activation | Low Anterior Resection

Canada, United States
Nanfang Hospital of Southern Medical University
LanZhou University; Beijing 302 Hospital; Xingtai People's Hospital; Southern Medical...

Recruiting

HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)

Portal Hypertension | Variceal Rebleeding

China
Beijing Chao Yang Hospital

Recruiting

Surgery Without Neoadjuvant Chemoradiotherapy Compared With Neoadjuvant Chemoradiotherapy for Rectal Cancer With Negative Circumferential Resection Margin Based on MRI Assessment, a Perspective Multicenter Randomized Controlled Trial (SCRM-01)

Local Recurrence of Malignant Tumor of Rectum | Circumferential Resection Margin | Intraoperative Perforation of Rectum | Disease-free Survival | Overal Survival

China
Centre Hospitalier Universitaire de Besancon
GERCOR - Multidisciplinary Oncology Cooperative Group

Recruiting

Adapted Physical Activity in Patients With Resected Pancreatic Cancer (APACaPOp PRODIGE-56 Study): a National Multicenter Randomized Controlled Phase II Trial (APACaPOp)

Quality of Life | Pancreas Cancer

France
Tongji Hospital

Recruiting

Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled Trial

Constipation

China
AgoneX Biopharmaceuticals, Inc.

Not yet recruiting

A Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of Subcutaneous AGX-201 for Migraine Prophylaxis

Migraine Prophylaxis
Universidad de Concepcion

Enrolling by invitation

Active Breaks on Mental Health and Classroom Climate in Chilean Schoolchildren Aged 6 to 10

Mental Health | School Health | School-age Children

Chile
Centre Hospitalier Universitaire Dijon

Completed

Evaluation of Non-opioid Balanced General Anesthesia in Cardiac Surgery With Extracorporeal Circulation: a Randomized, Controlled, Multicenter Superiority Trial (OFACAR)

Cardiac Surgery | Opioid-free Anesthesia

France
Sanofi
Regeneron Pharmaceuticals

Completed

A Phase 4, Randomized, Double-blind, Placebo-controlled,Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent Asthma (MORPHEO)

Asthma

Spain, United States, Argentina, Canada, Germany, Italy, Netherlands, Portugal, Russian Federation, Ukraine, United Kingdom
Shanghai Eye Disease Prevention and Treatment Center
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai... and other collaborators

Completed

The Effectiveness and Safety of Low-intensity Single-wavelength Red Light in Controlling High Myopia in Children and Adolescents：A Randomized, Controlled, Multicenter Clinical Trial

Age 3 to 16 Years (Inclusive), Male or Female | Clinical Diagnosis Confirming That Myopia Has Occurred in at Least One Eye | The Guardian Voluntarily Signed the Subject's Informed Consent Form

China
Medesis Pharma SA

Terminated

NanoMn®_COVID-19 A Prospective, Multicenter, Randomized, Placebo-controlled, Parallel-group, Double-blind Trial to Evaluate the Clinical Efficacy of NanoManganese® on Top of Standard of Care, in Adult Patients With Moderate to Severe Coronavirus Disease 2019 (COVID-19)

COVID-19 Pandemic

Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR); Medtronic

Completed

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial (RAFT)

Heart Failure, Congestive

Canada, Netherlands, Australia, Turkey, Denmark, Germany, Belgium
AbbVie

Completed

A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

Ulcerative Colitis (UC)

United States, Argentina, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Denmark, Egypt, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Mexico, Nether... and more
VA Office of Research and Development

Completed

Integrating Care After Exacerbation of COPD (InCasE)

Chronic Obstructive Pulmonary Disease

United States
Beijing Tiantan Hospital
Ministry of Science and Technology of the People's Republic of China

Active, not recruiting

Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis (INSPIRES)

Transient Ischemic Attack | Acute Stroke

China
Sandoz

Completed

Prospective, Randomized, Multinational, Multicenter, Double-blind, Placebo and Active Controlled Trial in 4 Parallel-groups of Patients Suffering From Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

Bulgaria, Germany, Poland, Moldova, Republic of
Eisai Inc.

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC) (SELECT)

Thyroid Cancer

United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, Czechia, Denmark, France, Germany, Italy, Japan, Korea, Republic of, Poland, Portugal, Romania, Russian Federation, Spain, Sweden, Thailand, United Kingdom
Rennes University Hospital

Completed

Retrograde Colonic Irrigation to Manage Spina Bifida Functional Digestive Sequelae: a Multicenter, Prospective, Randomized Controlled Trial (IRRICO)

Spina Bifida

France
Beijing Tiantan Hospital
Tasly Pharmaceutical Group Co., Ltd

Active, not recruiting

CerebrAlcare Pills on CereBral Small VesseL DiseasE（CABLE）

Cerebral Small Vessel Diseases

China
Assistance Publique - Hôpitaux de Paris

Completed

Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides (STATVAS)

ANCA-associated Primary Necrotizing Vasculitides

France
3M

Completed

Randomized, Controlled Multicenter Trial of Vacuum Assisted Closure Therapy™ in Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States, Canada
Teijin Pharma Limited

Completed

A Randomized Placebo-controlled Multicenter Trial to Evaluate the Efficacy and Safety of JTR-161, Allogeneic Human Dental Pulp Stem Cell, in Patients With Acute Ischemic stRoke (J-REPAIR) (J-REPAIR)

Acute Ischemic Stroke

Japan
Hospices Civils de Lyon

Completed

Surgical Treatment of Spinal Deformity With Sagittal Imbalance Using Patient-specific Rods: A Multicenter, Controlled, Double- Blind Randomized Trial: The PROFILE Study (PROFILE)

Spinal Deformity With Sagittal Imbalance
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of MN Recombinant Soluble gp120/HIV-1 (rsgp120/HIV-1) (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 MN rsgp120 and Bivalent AIDSVAX B/E (HIV-1 MN rgp120/A244 rgp120) in Combination With QS-21 With or Without Alum in Healthy HIV-1 Uninfected Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of rgp120/HIV-1MN (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults.

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Protein Sciences Corporation

Completed

A Phase I Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of Low Dose MN rsgp120/HIV-1 (Genentech) in Combination With QS21 Adjuvant or Alum in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Three Preparations of Low-Dose Oral Alpha Interferon in HIV-Infected Patients With CD4+ Counts >= 50 and <= 350 Cells/mm3

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blinded, Phase I Trial to Evaluate the Safety and Immunogenicity of Live Recombinant Canarypox ALVAC-HIV vCP205 Combined With GM-CSF in Healthy, HIV-1 Uninfected Volunteers

HIV Infections

United States
Yusup subagio sutanto

Completed

Pedometer Assisted Physical Activity in Individuals With COPD. A Multicenter Randomized Controlled Trial.

Chronic Obstructive Pulmonary Disease (COPD)

Indonesia
National Institute of Allergy and Infectious Diseases...

Withdrawn

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of an HIV-1 Pseudovirion Vaccine

HIV Infections
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of the Therion Recombinant Vaccinia-HIV-1 IIIB ENV/GAG/POL Vaccine (TCB-3B) and MN RGP 120/HIV-1 In Alum.

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial to Evaluate the Safety and Immunogenicity of a Recombinant Vaccinia-HIV-1 IIIB Env/Gag/Pol Vaccine (TBC-3B)

HIV Infections

United States
Holy Stone Healthcare Co., Ltd
inVentiv Health Clinical

Completed

A Phase 2a, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Trial of IBD98-M

Colitis, Ulcerative

Italy
Gachon University Gil Oriental Medical Hospital
Kyung Hee University Hospital at Gangdong; Kyunghee University Medical Center; Sangji University Oriental Medical Hospital and other collaborators

Completed

Efficacy and Safety of Ucha-Shinki-Hwan on Korean Patients With Cold Hypersensitivity in the Hands and Feet-Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial

Cold Hypersensitivity

Korea, Republic of
Annu Navani
Andrews Research & Education Foundation

Completed

The Use of PRP and BMC in Patients With Internal Disc Disruption Multicenter Prospective Randomized Controlled Trial in Patients With Internal Disc Disruption

Internal Disc Disruption

United States
Merck Sharp & Dohme LLC

Terminated

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Safety, Tolerability, and Efficacy of MK-8457 in Participants With Rheumatoid Arthritis (MK-8457-010)

Rheumatoid Arthritis
Universidade Federal do Rio de Janeiro
Financiadora de Estudos e Projetos; Hospital Universitario Pedro Ernesto; National... and other collaborators

Completed

Nitazoxanide Therapy for Patients With COVID-19 Pneumonia

Pneumonia, Viral | Covid19 | Corona Virus Infection

Brazil
Pfizer

Completed

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee

Osteoarthritis, Knee

Korea, Republic of, United States
Jaseng Medical Foundation

Completed

Efficacy and Safety of JHG002 for Chronic Temporomandibular Joint Dysfunction: A Multicenter Randomized Controlled Trial

Temporomandibular Disorder

Korea, Republic of
Major Extremity Trauma Research Consortium

Completed

Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO) (VANCO)

Post Operative Surgical Site Infection

United States
Danderyd Hospital
Uppsala University Hospital

Terminated

Swedish Rectal Prolapse Trial

Rectal Prolapse

Sweden
University Hospital, Angers
Mylan Laboratories

Completed

COvid-19 and Vitamin D Supplementation: a Multicenter Randomized Controlled Trial of High Dose Versus Standard Dose Vitamin D3 in High-risk COVID-19 Patients (CoVitTrial)

Coronavirus

France
Daiichi Sankyo, Inc.

Completed

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of SUN13834 in Adult Subjects With Atopic Dermatitis

Atopic Dermatitis

United States
Gachon University Gil Oriental Medical Hospital
DongGuk University; Sangji University Oriental Medical Hospital, Korea

Completed

A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors - Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial -

Obesity | Metabolic Syndrome

Korea, Republic of
Chinese PLA General Hospital

Active, not recruiting

Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study

Ablation | Benign Thyroid Nodules

China

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