Search clinical trials for: neutrophilic elastase

Total 166 results

Hospital Universitari Vall d'Hebron Research Institute
Bayer; Sociedad Española de Neumología y Cirugía Torácica; Instituto de Salud...

Completed

Inhaled A1AT in Adult Stable Bronchiectasis

Bronchiectasis Adult
Centre Hospitalier Intercommunal Creteil

Not yet recruiting

Real World Environmental Exposure Study With Healthy and Cystic Fibrosis Subjects (ExpoCF)

Environmental Exposure | Cystic Fibrosis, Pulmonary | Exhaled Breath Condansate
University of Leipzig

Recruiting

The Pancreatic Enzymes After Gastrectomy Trial

Gastrectomy

Germany
Qilu Hospital of Shandong University
LanZhou University; First Affiliated Hospital, Sun Yat-Sen University; Wuhan... and other collaborators

Recruiting

Pancreatic Cancer Screening Through the Detection of Elastase-1 Combined With Other Examinations

Pancreatic Neoplasms | Pancreatic Diseases | Pancreatitis | Pancreatic Ductal Adenocarcinoma | Pancreatic Neuroendocrine Tumor | Pancreatic Elastase 1

China
Changhai Hospital
Ruijin Hospital; Shanghai General Hospital, Shanghai Jiao Tong University School...

Recruiting

Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function Tests

Diabetes Mellitus | Chronic Pancreatitis | Pancreatic Exocrine Insufficiency | Community Populations | Fecal Elastase-1 Test

China
Assiut University

Not yet recruiting

Screening for Pancreatic Exocrine Insufficieny in Metabolic Associated Fatty Liver Disease Patients

Pancreatic Exocrine Insufficiency
Hospital Clinico Universitario de Santiago

Recruiting

Morphological Pancreatic Features in Diabetes Mellitus Type 2 (PANDIAM)

Diabetes Mellitus, Type 2

Spain
The First Hospital of Jilin University

Not yet recruiting

Neutrophil Elastase Inhibitor in Treatment of ARDS Patients With Mechanical Ventilation Caused by Sepsis

Acute Respiratory Distress Syndrome
Universitair Ziekenhuis Brussel

Not yet recruiting

Real-world Efficacy and Safety of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulator Therapy in Adult Patients With Cystic Fibrosis (CF)

Cystic Fibrosis
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Recruiting

Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)

MDS | Myeloproliferative Neoplasm | Chronic Neutrophilic Leukemia

United States
Universität Duisburg-Essen
Sozialstiftung Bamberg; Enterosan Labor LS SE & Co.KG

Recruiting

A Diagnostic Accuracy Study Testing Fecal Biomarkers In Comparison To Endoscopic Examination

Inflammatory Bowel Diseases

Germany
Rush University Medical Center

Recruiting

Role of Pancreatic Exocrine Secretion in Weight Gain After Pancreas Transplantation

Weight Gain | Exocrine Pancreatic Insufficiency

United States
Fundació Institut de Recerca de l'Hospital de la...
GlaxoSmithKline; Sociedad Española de Neumología y Cirugía Torácica

Recruiting

Microbiome and Exacerbations in Neutrophilic Asthma (AsmaEx)

Asthma | Microbiome | Exacerbation

Spain
R-Pharm Overseas, Inc.
Worldwide Clinical Trials

Not yet recruiting

Study of the Efficacy and Safety of RPH-104 in Adult Subjects With Schnitzler Syndrome

Schnitzler Syndrome | Urticarial Vasculitis With Monoclonal Immunoglobulin M Component, Schnitzler (Disorder)

United States
Hospital for Special Surgery, New York
Children's Healthcare of Atlanta; Campbell Clinic; Pediatric Orthopaedic Society... and other collaborators

Recruiting

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Septic Arthritis | Joint Infection | Infection of Hip Joint (Disorder) | Infection of Shoulder Joint

United States
National Cancer Institute (NCI)

Recruiting

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

Bronchiolitis Obliterans Syndrome | Chronic Graft vs Host Disease | Chronic Graft-Versus-Host Disease

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Registry of Older Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Cognitive/Functional Effects | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Eli Lilly and Company

Active, not recruiting

A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS

Aicardi Goutieres Syndrome | Nakajo-Nishimura Syndrome | Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature Syndrome | STING-Associated Vasculopathy With Onset in Infancy

Japan
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Precancerous/Nonmalignant Condition
Gangnam Severance Hospital

Active, not recruiting

New Predictive Marker for Pancreatic Cancer Using CA19-9 and Fecal Elastase

Paancreatic Cancer

Korea, Republic of
Fundació Institut de Recerca de l'Hospital de la...
Spanish Clinical Research Network - SCReN

Completed

Non-Eosinophilic Neutrophilic Asthma (ANNE)

Neutrophilic Asthma

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Neutrophilic Leukemia | Myeloid Neoplasm | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative | Myelodysplastic/Myeloproliferative... and other conditions

United States
Carlos Wambier
Brown University; Sun Pharmaceutical Industries Limited; Lifespan; Ocean State...

Active, not recruiting

Effects of Tildrakizumab on Epigenetic Age

Psoriasis | Aging | Inflammation; Skin | Epigenetic Disorder

United States
Eli Lilly and Company

No longer available

Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes

Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE) | Juvenile Dermatomyositis (JDM) | Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI) | Aicardi-Goutières Syndrome (AGS)

United States, United Kingdom
Mansoura University Hospital
Azza Tarik Eliwa; Ahmed Elsayed Mansour; Taha Taha Abdelgawad; Ahmed Mohamed Fouda

Completed

Airway Inflammation, Small Airways Dysfunction, and Frequency of Exacerbations in COPD

COPD Exacerbation Acute

Egypt
University of Nebraska
National Cancer Institute (NCI)

Withdrawn

Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Nonmalignant Neoplasm

United States
Astex Pharmaceuticals, Inc.

Terminated

A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm

United States, Canada
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Suspended

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Changhai Hospital
Peking Union Medical College Hospital; Xuanwu Hospital, Beijing

Completed

PE-1 in the Diagnosis of Pancreatic Exocrine Insufficiency

Pancreatic Exocrine Insufficiency

China
Insmed Incorporated

Completed

Assessment of INS1007 in Participants With Non-Cystic Fibrosis Bronchiectasis

Non-Cystic Fibrosis Bronchiectasis

United States, Spain, Korea, Republic of, Australia, Denmark, United Kingdom, Italy, Belgium, Singapore, Bulgaria, Germany, Netherlands, New Zealand, Poland
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent... and other conditions

United States
Roswell Park Cancer Institute

Completed

Sargramostim in Reducing Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplantation for Hematologic Cancer or Aplastic Anemia

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United States
Mereo BioPharma
Syneos Health

Completed

A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo. (ASTRAEUS)

Emphysema | Alpha 1-Antitrypsin Deficiency | COPD

United Kingdom, Belgium, United States, Denmark, Canada, Sweden, Poland, Spain
Santhera Pharmaceuticals

Completed

Clinical Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of POL6014 in Patients With CF

Cystic Fibrosis

Germany
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Withdrawn

Collecting and Storing Blood Samples From Patients With Cancer

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder and other conditions
Northwestern University
National Cancer Institute (NCI)

Completed

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Secondary...

United States
Baskent University
Selcuk University

Completed

Neutrophil Elastase, Elastase Alpha-1 Proteinase, Periodontitis, Gingival Crevicular Fluid and Acute Coronary Syndrome

Periodontitis | Acute Coronary Syndrome
Fred Hutchinson Cancer Center

Completed

Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

Primary Myelofibrosis | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated... and other conditions

United States
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI)

Completed

Bone Marrow Transplant in Treating Patients With Hematologic Cancers

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Neoplasms | Multiple Myeloma and Malignant Plasma Cell Neoplasms

United States
Corporacion Parc Tauli

Completed

Prevalence of Exocrine Pancreatic Insufficiency in Patients With Decompensated Cirrhosis ((EPIIHC))

Exocrine Pancreatic Insufficiency

Spain
OHSU Knight Cancer Institute

Completed

Ruxolitinib Phosphate in Treating Patients With Chronic Neutrophilic Leukemia or Atypical Chronic Myeloid Leukemia

Chronic Neutrophilic Leukemia | Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative

United States
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

PET Assessment of Acute Lung Transplant Rejection

Lung Disease

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
Jonsson Comprehensive Cancer Center

Completed

Voriconazole Compared With Itraconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Cancer

United States
Case Comprehensive Cancer Center

Completed

Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Severe Aplastic Anemia

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
University of Dundee
Boehringer Ingelheim; NHS Tayside

Completed

INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and Olodaterol (INCOGNITO)

Chronic Obstructive Pulmonary Disease

United Kingdom
NCIC Clinical Trials Group

Completed

Treatment for Chronic Pain in Patients With Advanced Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

Canada
University of Liege

Completed

Effect of Spinal or Sevoflurane Anesthesia on Neutrophil Activation During Knee Surgery With Pneumatic Tourniquet

Knee Surgery With Tourniquet

Search clinical trials for: neutrophilic elastase

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