Search clinical trials for: open-label extension study

Total 119505 results

Novartis Pharmaceuticals

Completed

CLCZ696B2319E1 OL Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF

Heart Failure

United States, Italy, Croatia, India, Japan, Poland, Spain, Taiwan, Austria, Korea, Republic of, Germany, Lebanon, Thailand, Canada, Bulgaria, Russian Federation, Turkey, Switzerland, Argentina, Hungary, Portugal, Finland, South Africa and more
Novartis Pharmaceuticals

Completed

Rainbow Extension Study (RainbowExt)

Retinopathy of Prematurity (ROP)

United States, Austria, Belgium, Croatia, Czechia, Denmark, Egypt, France, Germany, Greece, Hungary, India, Italy, Japan, Malaysia, Romania, Russian Federation, Saudi Arabia, Slovakia, Taiwan, Turkey, United Kingdom, Lithuania, Estonia
Dermavant Sciences GmbH
IQVIA Biotech

Completed

Long Term Extension Study of Tapinarof for Plaque Psoriasis in Adults (3003)

Plaque Psoriasis

United States, Canada
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Extension Study Of Long-Term Safety And Efficacy Of Pregabalin As Monotherapy (Lyrica) In Patients With Partial Seizures

Epilepsy

United States, Ukraine, Hong Kong, Czechia
GlaxoSmithKline

Completed

A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622

Hypereosinophilic Syndrome

United States, Poland, Spain, France, Belgium, Germany, Argentina, Russian Federation, Mexico, Italy, Brazil, United Kingdom, Romania
Novartis Pharmaceuticals

Completed

A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures (EXIST-3)

Tuberous Sclerosis Complex-associated Refractory Seizures

United States, Colombia, Belgium, France, Japan, Taiwan, Turkey, Spain, Thailand, Korea, Republic of, Australia, Hungary, United Kingdom, Canada, Norway, Germany, Italy, Russian Federation, Denmark, Argentina, Netherlands, Greece, P... and more
BioMarin Pharmaceutical

Terminated

A Study of the Safety, Tolerability & Efficacy of Long-term Administration of Drisapersen in US & Canadian Subjects

Muscular Dystrophies

United States, Canada
AbbVie (prior sponsor, Abbott)

Completed

Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa (PIONEER (OLE))

Hidradenitis Suppurativa
GlaxoSmithKline

Terminated

Open-Label Extension Study Of Rosiglitazone XR As Adjunctive Therapy In Subjects With Mild-to-Moderate Alzheimers

Alzheimer's Disease

Australia, Spain, United States, Bulgaria, Germany, Belgium, Canada, Hong Kong, Korea, Republic of, Portugal, Argentina, Chile, Greece, Slovenia, Czechia, France, Hungary, Italy, South Africa, India, Sweden, Netherlands, Philippines, ... and more
GlaxoSmithKline

Terminated

Study Of Rosiglitazone XR In Subjects With Mild-to-Moderate Alzheimers

Alzheimer's Disease

United States, Bulgaria, Germany, Estonia, Korea, Republic of, China, Greece, Hungary, Russian Federation, Philippines, Austria, Chile, Mexico, Croatia, New Zealand, Peru, Puerto Rico, United Kingdom
Tonix Pharmaceuticals, Inc.

Completed

Open Label Extension Safety and Efficacy Study of TNX-102 SL Tablets in Military Related PTSD and Related Conditions (P202)

PTSD

United States
Pfizer

Terminated

A Phase 2 Extension Study To Enroll Subjects Who Were Enrolled In B5301001 Study

Hypertrophic Scars Resulting From Prior Breast Scar Revision Surgery

United States
GlaxoSmithKline

Completed

Long-term Extension Study Evaluating Extended Release Ropinirole XL (Formerly Referred to as Ropinirole CR) in Patients Who Already Completed Either Study 167 or 164

Parkinson Disease

United States
UCB Biopharma SRL

Not yet recruiting

An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis (ziMyG+)

Generalized Myasthenia Gravis
Zydus Therapeutics Inc.

Not yet recruiting

Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Turkey, Argentina
Biohaven Therapeutics Ltd.

Not yet recruiting

BHV-7000 Open-Label Extension Bipolar Mania Study

Bipolar Disorder
Takeda

Not yet recruiting

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease | Ulcerative Colitis
Constellation Pharmaceuticals

Not yet recruiting

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Solid Tumor | Hematologic Malignancy | Advanced Malignancies
The University of Texas Health Science Center,...
Brighter Bites and Humana Foundation

Not yet recruiting

Brighter Bites & University of Texas Physicians Produce Rx Extension: Evaluating the Effectiveness of a Prospective Clinical Nutrition Study With Produce Prescriptions

Obesity, Childhood

United States
Novartis Pharmaceuticals

Recruiting

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR) (REPLENISH-EXT)

Polymyalgia Rheumatica

Australia
University Hospital, Bordeaux

Recruiting

Fluid Responsiveness Evaluation by a Non-invasive Method in Children, Extended to PREterm Infants - FRENCH-PREMA (FRENCH-PREMA)

Premature Baby 26 to 32 Weeks | Premature Baby 33 to 36 Weeks

France
GB002, Inc.

Not yet recruiting

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

Pulmonary Arterial Hypertension

United States
PTC Therapeutics

Recruiting

An Extension Study to Evaluate the Long-Term Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD)

Huntington Disease

Australia, France, Germany, Netherlands, United Kingdom, Spain, Austria, Canada, Italy, New Zealand
NextPoint Therapeutics, Inc.

Recruiting

A Study of NPX887 for Participants With Solid Tumors Known to Express HHLA2/B7-H7

Metastatic Malignant Neoplasm

United States
Incyte Corporation

Recruiting

A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa (STOP-HS LTE)

Hidradenitis Suppurativa (HS)

United States, Austria, Belgium, Canada, Germany, Poland, Spain, Australia, Denmark, France, United Kingdom, Japan, Bulgaria, Netherlands, Czechia, Greece, Italy
PharmAust Ltd
Macquarie University, Australia; Calvary Health Care Bethlehem

Recruiting

An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease

Motor Neuron Disease

Australia
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
Novartis Pharmaceuticals

Recruiting

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension). (SIRIUS-SLE LTE)

Systemic Lupus Erythematosus

Spain
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Multicenter, Open-label Extension Study Evaluating the Efficacy and Safety of IBI311 in Subjects With Thyroid Eye Disease

Thyroid Eye Disease, TED

China
Sling Therapeutics, Inc.

Recruiting

A Phase 2b Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Eye Diseases | Endocrine System Diseases | Thyroid Diseases | Thyroid Eye Disease | Graves Ophthalmopathy | Exophthalmos | Orbital Diseases | Thyroid Associated Ophthalmopathy | Graves Orbitopathy | Proptosis | IGF1R | Hashimoto

United States
TWi Biotechnology, Inc.

Recruiting

An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)

Generalized Epidermolysis Bullosa Simplex

United States, Taiwan, Australia, Philippines, Austria, Italy, Poland
Click Therapeutics, Inc.
Boehringer Ingelheim

Recruiting

An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia

Schizophrenia | Negative Symptoms in Schizophrenia

United States
Pfizer

Recruiting

Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM) (MagnetisMM15)

Multiple Myeloma

Canada, France, Japan, Australia, United States
Takeda

Recruiting

Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment

Hunter Syndrome

Canada, France
Novartis Pharmaceuticals

Recruiting

A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome. (NEPTUNUS-Ext)

Sjogrens Syndrome

Japan, United States, Spain, Austria, Belgium, Germany, Turkey, Hungary, Israel, Taiwan, Italy, France, Colombia, Argentina, Portugal, Australia, Slovakia, United Kingdom, Guatemala, Brazil, Czechia, Poland, Bulgaria, Canada, Lithuania, R...
GPN Vaccines

Recruiting

Extension Safety and Immunogenicity Study of GPNV-001

Pneumococcal Infections

Australia
Mineralys Therapeutics Inc.

Recruiting

Open-Label Extension Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Uncontrolled Hypertension

Hypertension

United States, Puerto Rico
University of Rochester
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Families Moving Forward (FMF) Connect Pro for Mental Health Providers

Fetal Alcohol Spectrum Disorders

United States
PharmAbcine
Merck Sharp & Dohme LLC; Novotech (Australia) Pty Limited

Not yet recruiting

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309 (MarkV-01)

Advanced or Metastatic Solid Tumors

Australia
NextPoint Therapeutics, Inc.

Recruiting

A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7

Metastatic Malignant Neoplasm

United States
Nyxoah S.A.
Nyxoah Pty. Ltd.

Not yet recruiting

An Extension Study to Assess the Long-term Safety of the Genio® System (OLE)

Obstructive Sleep Apnea of Adult

Australia
Medical University of South Carolina
The Skin Center Dermatology Group

Recruiting

Cold Atmospheric Plasma Device Extension Study

Verruca Vulgaris | Molluscum Contagiosum

United States
Auburn University

Recruiting

Sleep and Vascular Health Study (SAVHS)

Vascular Diseases | Sleep | Metabolic Disease

United States
Novartis Pharmaceuticals

Recruiting

An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) (OLE)

Hyperlipoproteinemia (a)

Germany
Inhibrx, Inc.

Not yet recruiting

Open Label Extension Study of INBRX-101 in Adults With AATD Emphysema (ELEVAATE OLE)

Emphysema | Alpha 1-Antitrypsin Deficiency
Tianjin Medical University Cancer Institute and...

Not yet recruiting

A Multicenter, Phase 2 Study Evaluating the Value of Radiotherapy in Advanced Diffuse Large B-cell Lymphoma Patients With Extranodal Involvement and Large Tumors Undergoing Immunochemotherapy for PET-CT Assessment of Complete Remission

Radiotherapy | Advanced Diffuse Large B-Cell Lymphoma | Extra-nodal Involvement, Large Mass
Newcastle-upon-Tyne Hospitals NHS Trust
KU Leuven; University College Dublin; University of Kiel; Tel-Aviv Sourasky Medical... and other collaborators

Recruiting

Mobilise-D: Extension Study

Parkinson Disease | Aging

United Kingdom
Ichnos Sciences SA

Not yet recruiting

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

Australia
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

Extension Study to Evaluate Safety and Efficacy of Jaktinib in Patients With Active Ankylosing Spondylitis(AS)

Ankylosing Spondylitis

China
Penn State University

Not yet recruiting

More Sleep: Pain Response to Longer Sleep

Pain | Sleep

Search clinical trials for: open-label extension study

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