Search clinical trials for: opiate antagonist

Total 33809 results

University of Colorado, Denver
Denver Health and Hospital Authority; Southern Colorado Harm Reduction Association and other collaborators

Not yet recruiting

Vending Machine Naloxone Distribution for Your Community (VENDY)

Harm Reduction | Naloxone | Opioid Overdose
University of New Mexico

Not yet recruiting

Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose

Opioid Overdose | Opiate Overdose

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use (ROLDI)

Opioid Use Disorder
University of Bordeaux

Recruiting

Introduction of Long Acting Buprenorphine in France (OBAP)

Addiction Opiate

France
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute...

Not yet recruiting

Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD (TOME)

Pregnancy Related | Substance Use | Opioid Use Disorder | Drug Abuse | Drug Addiction | Drug Abuse in Pregnancy
University of California, San Francisco

Not yet recruiting

Naloxone for Opioid Associated Out of Hospital Cardiac Arrest (NOPACA)

Heart Arrest, Out-Of-Hospital | Naloxone | Opioid Overdose

United States
University of Missouri-Columbia

Not yet recruiting

Opioid Rapid Response System: Naloxone Training in Communities

Opioid Overdose
University of Pennsylvania

Recruiting

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal (UH3)

Opioid Use | Opiate Withdrawal Syndrome

United States
RTI International
University of California, San Diego; Heluna Health

Recruiting

Improving Equitable Access to Naloxone to Prevent Opioid Overdose Deaths Within Syringe Service Programs (SAIA-Naloxone) (SAIA-N)

Overdose | Implementation as Usual

United States
Hartford Hospital
Hartford HealthCare

Not yet recruiting

Improving Availability of Intranasal Naloxone

Opioid Overdose

United States
Johns Hopkins University
DEKA S.r.l.

Not yet recruiting

Blood Naloxone Levels Following Intradermal Injection in Humans

Opioid Overdose
Royal Victoria Hospital, Canada

Not yet recruiting

Monthly Versus Daily Buprenorphine Formulations for Treatment of Opiate Use Disorder (STOPIT)

Moderate to Severe Opioid Use Disorder

Canada
Johns Hopkins University

Recruiting

Suvorexant for Opioid/Stimulant Co-use

Opioid Use Disorder | Stimulant Use Disorder

United States
Nationwide Children's Hospital

Recruiting

Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit Stimulants

Harm Reduction | Opiate Overdose | Fentanyl Overdose

United States
King's College London
Mundipharma Research Limited

Recruiting

European Cohort Study of the Effectiveness of Take Home Naloxone (NalPORS)

Opioid Overdose

Denmark, United Kingdom, Sweden
DemeRx IB, Inc.
Hammersmith Medicines Research; ERT: Clinical Trial Technology Solutions; MAC...

Recruiting

A Study of Oral Ibogaine in Opioid Withdrawal

Opiate Withdrawal Syndrome

United Kingdom
Carilion Clinic
Virginia Polytechnic Institute and State University

Not yet recruiting

Naloxone Education in Total Joint Patients

Surgery | Opioid Use | Pain, Musculoskeletal | Overdose of Opiate

United States
BC Centre on Substance Use
Indivior Inc.

Recruiting

Extended-release Injectable Buprenorphine for Individuals at High Risk of Overdose (FASTER-BUP)

Opioid Overdose | Opioid-Use Disorder

Canada
The University of Texas Health Science Center,...

Recruiting

Young Houston Emergency Opioid Engagement System (YHEROES)

Substance Use Disorders | Opioid Dependence | Opioid Use | Opioid-use Disorder | Opioid Overdose

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Patient and Caregiver Attitudes and Beliefs Regarding Prescription of Intranasal Naloxone Spray for Opioid Overdose

Caregiver | Patient

United States
Stanford University

Recruiting

Opiate Suicide Study in Patients With Major Depression (AFSP)

Major Depressive Disorder

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-study (MOMs-INO)

Pregnancy Related | Opioid-Related Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Neonatal Abstinence Syndrome | Neonatal Opiate Withdrawal Syndrome | Drug Abuse in Pregnancy

United States
Friends Research Institute, Inc.
National Institute on Drug Abuse (NIDA)

Recruiting

Long-acting Naltrexone for Pre-release Prisoners

Opiate Addiction

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Recruiting

Substance Abuse Pre-Treatment Screening Study

Alcohol Dependence | Substance Abuse | Cocaine Dependence | Opiate Dependence | Cocaine Abuse

United States
Steve N. Caritis, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy

Pregnancy | Opiate Addiction

United States
University of Pittsburgh

Completed

Impact of Pregnancy on Buprenorphine Pharmacokinetics and Pharmacodynamics

Pregnancy | Opiate Addiction

United States
April M Young
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Sexually Transmitted Diseases | Opioid-Related Disorders | Substance Abuse | Drug Overdose | Opiate Substitution Treatment | Human Immunodeficiency Virus (HIV) | Hepatitis C (HCV) | Intravenous Drug Usage

United States
Montefiore Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Onsite Buprenorphine Treatment at Syringe Exchange Programs (O-BMT)

Opiate Addiction

United States
Trustees of Dartmouth College
Patient-Centered Outcomes Research Institute

Completed

MOms in REcovery (MORE) Study: Defining Optimal Care (MORE)

Opioid-Related Disorders | Substance Use Disorders | NAS

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Impact of Lofexidine on Stress, Craving and Opioid Use

Opioid-use Disorder | Opiate Dependence

United States
Emergent BioSolutions

Completed

Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults

Opioid Overdose

United States
Brown University
National Institute on Drug Abuse (NIDA)

Completed

The Rhode Island Prescription and Illicit Drug Study (RAPIDS)

Drug Overdose | Opioid Overdose

United States
Brown University
National Institute on Drug Abuse (NIDA); New York University

Active, not recruiting

Preventing Overdose Using Information and Data From the Environment (PROVIDENT)

Drug Overdose | Opioid Overdose

United States
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Use of a GLP-1R Agonist to Treat Opioid Use Disorder

Opioid-Related Disorders | Opiate Substitution Treatment

United States
Johns Hopkins Bloomberg School of Public Health
Centers for Disease Control and Prevention

Completed

An Evaluation of a Social Network Intervention for Primary and Secondary Prevention of Opioid Overdoses

Overdose

United States
King's College London
NHS Tayside; Bangor University; South London and Maudsley NHS Foundation Trust; Greater Manchester Mental Health NHS Foundation Trust and other collaborators

Completed

Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO)

Opiate Substitution Treatment

United Kingdom
NYU Langone Health
Centers for Disease Control and Prevention

Completed

Multi-Center Randomized Controlled Trial of Relay- NYC's Nonfatal Overdose Response Program

Opioid Overdose

United States
VA Office of Research and Development

Terminated

Optimal Treatment of Veterans With PTSD and Comorbid OUD

Post-Traumatic Stress Disorders | Opiate Use Disorder

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal (RELEASE)

Opioid Withdrawal

United States
Kaiser Permanente
Henry Ford Health System

Active, not recruiting

Health Insurance Instability and Mortality Among Patients Receiving Bup Tx for OUD

Death | Opioid Use Disorder | Opioid Overdose

United States
Kaiser Permanente
National Institute of Mental Health (NIMH); Boston Medical Center; University... and other collaborators

Active, not recruiting

More Individualized Care: Assessment and Recovery Through Engagement (MI-CARE)

Depression | Anxiety | Opioid-Related Disorders | Pain, Chronic

United States
University of Pennsylvania
Public Health Management Corporation; Philadelphia Department of Public Health and other collaborators

Completed

Rapid Initiation of Drug Treatment Engagement (RIDE)

Overdose | Opioid-use Disorder

United States
New York State Psychiatric Institute

Suspended

Tailoring Overdose Education for Black Churches

Opioid Overdose

United States
New York State Psychiatric Institute

Suspended

Vaped Marijuana to Attenuate Naloxone-Precipitated Withdrawal

Opioid Overdose

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Remote Observed Dosing of Suboxone to Improve Clinical Practice

Opioid Dependence | Opioid-use Disorder | Opiate Dependence

United States
Purdue Pharma LP

Withdrawn

Clinical Outcomes From Nalmefene (COINED)

Opioid Overdose
M.D. Anderson Cancer Center

Withdrawn

Gabapentin for the Reduction of Opiate Use Following Pulmonary Resection (GROUP Trial)

Pulmonary Disease | Thoracic

United States
Indivior Inc.

Completed

Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED) (OPUS R)

Naloxone | Drug Abuse | Opiate Dependence | Buprenorphine | Opiate-related Disorders
Indivior Inc.

Completed

Preference for Subutex® (Buprenorphine) Versus Suboxone® (Buprenorphine/Naloxone) in Opioid Dependent Patients on Subutex® (Study P05094)(COMPLETED)

Drug Abuse | Opiate Dependence | Opiate-related Disorders
West Virginia University
West Virginia Clinical and Translational Science Institute

Withdrawn

Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population (SUPER-ERAS)

Fractures, Bone | Chronic Pain | Addiction Opiate | Buprenorphine Dependence

United States

Search clinical trials for: opiate antagonist

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