Search clinical trials for: opioid agonist treatment

Total 80104 results

USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Recruiting

Pharmacokinetic and Safety Study of Oral Lofexidine in Neonates Experiencing Opioid Withdrawal Due to Intrauterine Exposure to Opioids

Opioid Withdrawal (Disorder)

United States
University of Pennsylvania

Recruiting

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal (UH3)

Opioid Use | Opiate Withdrawal Syndrome

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Clinical Study on the Effect of Tizanidine on the Function and Pain of Patients After Shoulder Arthroscopy

Rotator Cuff Tears
Parnassia Addiction Research Centre
Radboud University Medical Center; Columbia University; Academisch Medisch Centrum... and other collaborators

Not yet recruiting

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Cocaine Use Disorder
VA Office of Research and Development

Recruiting

An Adaptive Walking Intervention to Manage Chronic Pain in Veterans With Opioid Use Disorder Engaged in Opioid Agonist Treatment

Chronic Pain | Opioid Use Disorder

United States
University of British Columbia

Recruiting

Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

Opioid-use Disorder

Canada
Massachusetts General Hospital

Recruiting

Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD

Sleep Disorder | Restless Legs Syndrome | Opioid-use Disorder | Opioid Withdrawal

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Recruiting

An Innovative Intervention for OUD Treatment (Bridge)

Opioid-Related Disorders | Opioid Dependence | Opioid Withdrawal | Opioid Addiction

United States
National Institute on Drug Abuse (NIDA)

Recruiting

Biased Opioid Agonists for Treatment of Opioid Withdrawal in OUD

Opioid-Use Disorder

United States
University of British Columbia
Vancouver Coastal Health

Recruiting

Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder

Opioid Use Disorder

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm

United States
EMS

Recruiting

Efficacy and Safety of Flamboyant 125/12 Association in the Treatment of Adults With Moderate Asthma

Asthma

Brazil
EMS

Recruiting

Efficacy and Safety of Flamboyant 200/12 Association in the Treatment of Adults With Severe Asthma

Asthma

Brazil
Centre Hospitalier Universitaire de Nīmes

Recruiting

Add-on Buprenorphine at Analgesic Doses for the Treatment of Severe Suicidal Ideas During a Major Depressive Episode (BUPRIS)

Suicidal Ideation | Major Depressive Episode

France
The Cooper Health System

Recruiting

Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy

Neonatal Abstinence Syndrome

United States
University of Pennsylvania

Completed

Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal (PGB-LOF)

Opioid Withdrawal

United States
Ukrainian Institute on Public Health Policy
Yale University; Alliance for Public Health

Active, not recruiting

Integrating Treatment for Mental Disorders in Methadone Clinics in Ukraine (MEDIUM)

Depression | Opioid Use Disorder

Ukraine
Henrietta Bada
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain (No-POPPY)

Neonatal Abstinence Syndrome

United States
Northwestern University
National Institutes of Health (NIH); Northwestern Medical Group

Withdrawn

Novel Non-opioid Post-surgical Pain Treatment in Females

Acute Pain | Bunionectomy | Toe Fusion

United States
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Use of a GLP-1R Agonist to Treat Opioid Use Disorder

Opioid-Related Disorders | Opiate Substitution Treatment

United States
Medipol University

Completed

Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Dental Treatment

Nausea | Postoperative Pain | Anxiety

Turkey
University of Vermont
National Institute on Drug Abuse (NIDA); Johns Hopkins University; University... and other collaborators

Completed

Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions (MOTHER DYAD)

Opioid-use Disorder | Neonatal Abstinence Syndrome | Opioid Withdrawal | Neonatal Opioid Withdrawal Syndrome

United States
Cairo University

Completed

Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics

Anesthesia

Egypt
BioXcel Therapeutics Inc
Cognitive Research Corporation

Completed

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal (RELEASE)

Opioid Withdrawal

United States
Haukeland University Hospital
University of Bergen; Helse Stavanger HF; Helse Vest; Forskningsrådet; Folkehelse... and other collaborators

Active, not recruiting

Integrated Treatment of Hepatitis C Virus Infection (INTRO-HCV)

Hepatitis C, Chronic | Opioid Dependence, on Agonist Therapy

Norway
Haukeland University Hospital
University of Bergen; Helse Stavanger HF; Helse Vest

Active, not recruiting

Integrated Exercise Program in Opioid Agonist Therapy Clinics (BAReAktiv)

Substance-Related Disorders

Norway
Haukeland University Hospital
University of Oslo; University of Bergen; Helse Stavanger HF; Helse Vest; ProLAR...

Active, not recruiting

Effect of Fruit Smoothie Supplementation on Psychological Distress Among People Receiving Opioid Agonist Therapy (FruktBAR)

Substance-Related Disorders

Norway
Haukeland University Hospital
University of Bergen; Helse Stavanger HF; Helse Vest

Active, not recruiting

Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco (BAReNikotin)

Substance-Related Disorders | Smoking Cessation

Norway
Daniel Benjamin
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (PTN_POPS)

Heart Failure | Epilepsy | Pain | Pneumonia | Sepsis | Inflammation | Hypertension | Chronic Kidney Diseases | Hemophilia | Schizophrenia | Central Nervous System Infections | Nosocomial Pneumonia | Insomnia | Anxiety | Bipolar Disorder | Neutropenia | Staphylococcal Infections | Bradycardia | Seizures | Urinary Tract Infections | Pulmonary... and other conditions

United States, Canada, United Kingdom, Israel, Singapore
Ain Shams University

Completed

Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery

Delirium
University of Arkansas
National Institute on Drug Abuse (NIDA)

Completed

Improving Treatment Outcomes for Prescription Opioid Dependence (GBN)

Drug Dependence

United States
Wake Forest University Health Sciences

Withdrawn

Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films

Opioid Use
UPECLIN HC FM Botucatu Unesp
Chiesi Farmaceutici S.p.A.

Active, not recruiting

Efficacy of Inhaled Therapies in the Treatment of Acute Symptoms Associated With COVID-19 (TRIVID)

Covid19

Brazil
Centre hospitalier de l'Université de Montréal...

Completed

Shivering Treatment After Cesarean Delivery: Meperidine vs. Dexmedetomidine

Cesarean Section Complications

Canada
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Efficacy, Safety and Dose-Response Study Followed by Open-Label Study of Lofexidine Treatment of Opioid Withdrawal

Opioid Dependence | Acute Opioid Withdrawal Syndrome

United States
USWM, LLC (dba US WorldMeds)

Suspended

Randomized, Double-Blind, Placebo-Controlled Pilot Study on the Safety and Effectiveness of LUCEMYRA During an Opioid Taper in Treatment of Withdrawal (TAPER)

Opioid Withdrawal (Disorder)

United States
Albert Einstein College of Medicine
National Institute on Drug Abuse (NIDA); Montefiore Medical Center; Fordham University

Completed

Neurocognitive Effects of Opiate Agonist Treatment (NEO)

HIV Infections | HIV | Opioid-Related Disorders

United States
New York State Psychiatric Institute
USWM, LLC (dba US WorldMeds)

Completed

Lofexidine for Management of Opioid Withdrawal With XR-NTX Treatment

Opioid-use Disorder

United States
Didier Jutras Aswad
Canadian Institutes of Health Research (CIHR)

Completed

A Pragmatic Randomized Control Trial Comparing Models of Care in the Management of Prescription Opioid Misuse (OPTIMA)

Opioid Use Disorder

Canada
Bausch Health Americas, Inc.

Completed

Dose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC) (OIC)

Constipation

United States
Virginia Commonwealth University
Indivior, PLC.

Withdrawn

Virginia Opioid Treatment-Emergency Department (VOT-ED)

Opioid Use Disorder
West Virginia University
National Institute on Drug Abuse (NIDA); Pfizer

Completed

Smoking Cessation & Opioid Dependence Treatment Integration

Smoking Cessation | Opioid Related Disorders

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Study of Computer-Based Treatment for Drug Dependence (RLSS)

Opioid-Related Disorders | Heroin Dependence

United States
Sucampo Pharma Americas, LLC

Completed

Opioid-induced Bowel Dysfunction: Long-Term Assessment of Lubiprostone

Opioid-Induced Bowel Dysfunction

United States, Canada
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

Opioid-induced Bowel Dysfunction: Pivotal Assessment of Lubiprostone (OPAL)

Opioid-Induced Bowel Dysfunction

United States, Canada
University of Erlangen-Nürnberg Medical School

Terminated

Cooling Plus Best Medical Treatment Versus Best Medical Treatment Alone for Acute Ischaemic Stroke (EuroHYP-1)

Acute Ischemic Stroke

Germany
Kaiser Permanente
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence

Opiate Substitution Treatment

United States
Butler Hospital
National Center for Complementary and Integrative Health (NCCIH)

Completed

Study of Yoga vs. Health Education for Chronic Pain in Persons Receiving Opioid Agonist Therapy

Opioid-Related Disorders | Pain, Chronic

United States
Hennepin Healthcare Research Institute

Completed

Utility of Olanzapine in the Treatment of Opioid Withdrawal in the ED

Substance Withdrawal Syndrome

United States
gicare Pharma Inc.
Algorithme Pharma Inc; JSS Medical Research Inc.

Completed

A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy

Pain | Cancer | Colonic Diseases

United States, Canada

Search clinical trials for: opioid agonist treatment

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belarus

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations