Search clinical trials for: oral doses

Total 20545 results

Eilean Therapeutics

Recruiting

Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers

AML

Australia
Shanghai Yao Yuan Biotechnology Ltd. (also known...

Not yet recruiting

Evaluating the Safety and Tolerability of Multiple Doses of Orally Administered DF-003 in ROSAH Syndrome Patients

ROSAH

Australia, United States
Foresee Pharmaceuticals Co., Ltd.
InClin, Inc.

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers

Healthy

Australia
ViiV Healthcare
GlaxoSmithKline

Not yet recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

HIV Infections

United States
Gilgamesh Pharmaceuticals

Recruiting

A Clinical Study to Evaluate of Single and Multiple Oral Doses of GM-1020 in Patients With MDD

Major Depressive Disorder

United Kingdom
James Tarbox, MD
Texas Tech University Health Sciences Center

Recruiting

Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge

Penicillin Allergy

United States
GEN İlaç ve Sağlık Ürünleri A.Ş.
Sulfateq B.V.

Recruiting

A First-In-Human Study of Single and Multiple Ascending Doses of Oral SUL-238 in Healthy Subjects

Healthy Subjects

Turkey
Biora Therapeutics, Inc.

Recruiting

BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects

Healthy

United States
Boehringer Ingelheim

Recruiting

A Study to Test Whether Multiple Doses of BI 456906 Have an Effect on Cardiac Safety in People With Overweight or Obesity

Obesity | Overweight

Germany
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects

Inflammatory Bowel Disease
GlaxoSmithKline
Medicines for Malaria Venture

Recruiting

A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants

Malaria, Falciparum

United Kingdom
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
AstraZeneca
Parexel

Recruiting

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants

Healthy Participants

United States
Toll Biotech Co. Ltd. (Beijing)

Recruiting

A Study of Single and Multiple Oral Doses of TollB-001

Rheumatoid Arthritis

China
Montreal Heart Institute
The Montreal Health Innovations Coordinating Center (MHICC); Ceapro Inc.

Recruiting

Single and Multiple Ascending Oral Doses of Avenanthramide (AvenActive)

Inflammation

Canada
YourChoice Therapeutics, Inc.

Recruiting

First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males

Male Contraception

United Kingdom
EicOsis Human Health Inc.

Recruiting

Safety, Tolerability, and Pharmacokinetics of Multiple Doses of Oral EC5026 in Healthy Subjects

Healthy Subjects

New Zealand
GlaxoSmithKline

Recruiting

Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Rotarix Porcine Circovirus (PCV)-Free Liquid Compared to Rotarix Liquid Given in 2-doses in Healthy Chinese Infants Starting at Age 6-16 Weeks

Gastroenteritis

China
University of Chile
Bharat Biotech International Limited

Recruiting

The Efficacy of Three Doses of Live Attenuated, Oral Rotavirus Vaccine 116E

Rotavirus Gastroenteritis

Chile
Boehringer Ingelheim

Recruiting

A Study in Women With Overweight or Obesity to Test Whether Different Doses of BI 456906 Influence the Amount of a Contraceptive in the Blood

Healthy

Germany
Ottawa Hospital Research Institute
The Ottawa Hospital Academic Medical Association; Network of Canadian Emergency...

Recruiting

High-dose Cephalexin for Cellulitis (HI-DOCC) (HI-DOCC)

Cellulitis

Canada
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects

Healthy Subjects

United States
Planned Parenthood League of Massachusetts

Recruiting

Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location

Abortion

United States
OrsoBio, Inc

Recruiting

A Study Evaluating Daily Oral Doses of TLC-3595 in Participants With Insulin Resistance

Insulin Resistance

New Zealand
SRI International

Recruiting

Study of Single Oral Doses of HOPO 14-1 Evaluating Safety, Tolerability, Pharmacokinetics

Toxicity;Chemical

United States
Afasci Inc

Recruiting

Phase I Single Ascending Dose and Multiple Ascending Doses of Oral AFA-281 in Healthy Volunteers

Pain, Neuropathic | Pain, Inflammatory

United States
Nanjing Immunophage Biotech Co., Ltd
Novotech (Australia) Pty Limited

Not yet recruiting

A Study of Orally Administered IPG7236 in Healthy Adult Participants

Atopic Dermatitis

Australia
Oral and Maxillofacial Surgery Clinic, Poland

Recruiting

Different Oral Doses of Clindamycin in Preventing Post-operative Sequelae of Lower Third Molar Surgery

Impacted Third Molar Tooth | Impacted Molar

Poland
Bazell Pharma AG

Not yet recruiting

Pharmacokinetics, Efficacy, Tolerability and Safety of Different Budesonide Oral Gel Doses in Adults' Subjects of Both Genders With Eosinophilic Esophagitis (EoE) (BESIDE)

Eosinophilic Esophagitis
Peking Union Medical College Hospital

Not yet recruiting

Efficacy and Safety of Adalimumab Plus Medium Dose Oral Glucocorticosteroid for Refractory Behçet's Uveitis

Uveitis
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH); Janssen, LP

Recruiting

An Evaluation of Repeated Oral Doses of JNJ-64281802 Against DENV-3 Challenge

Dengue

United States
Kafrelsheikh University

Not yet recruiting

Investigating the Role of 13cis Retinoic Acid in the Treatment of COVID-19 and Enhancement of Its Spike Protein Based Vaccine Efficacy and Safety. (Isotretinoin)

Covid19 Vaccine
University of Nottingham
Sanofi

Recruiting

MRI Assessment of Mode of Action of Bisacodyl, Multiple Doses (MODEM)

Constipation

United Kingdom
Cecilia Soderberg-Naucler
Karolinska University Hospital; Karolinska Institutet

Recruiting

A Clinical Trial Evaluating the Efficacy of Valganciclovir in Glioblastoma Patients (VIGAS2)

Glioblastoma Multiforme

Sweden
Southern California Institute for Research and...

Recruiting

A Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine

Non-Alcoholic Fatty Liver Disease | Non Insulin Dependent Diabetes | ALT

United States
EMS

Recruiting

Efficacy and Safety of Three Doses of Florence Oral Suspension in Adults With Eosinophilic Esophagitis

Eosinophilic Esophagitis

Brazil
Madrigal Pharmaceuticals, Inc.

Enrolling by invitation

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control Subjects With Normal Renal Function

Renal Impairment

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States, China
Hartford Hospital
Yale University

Active, not recruiting

Hippocampal Response to Acute Oral Doses of CBD During an fMRI Memory Task

CBD

United States
Novo Nordisk A/S

Completed

Research Study to Compare Three Doses of Semaglutide Tablets Taken Once Daily in People With Type 2 Diabetes (PIONEER PLUS)

Diabetes Mellitus, Type 2

United States, India, Taiwan, Poland, Australia, Estonia, Hungary, Germany, Slovakia, Canada, Croatia, Bulgaria, Puerto Rico, Czechia, Slovenia
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How the Body Takes up and Tolerates Different Doses of BI 474121, and Whether it Makes a Difference if BI 474121 is Taken as a Tablet or a Drink.

Healthy

Germany
Hinova Pharmaceuticals Aus Pty Ltd

Completed

A Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer

Australia
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Neurocrine Biosciences
Takeda

Completed

A Study to Evaluate Multiple Oral Doses of Luvadaxistat in Adults With Schizophrenia

Schizophrenia

United States
Novartis Pharmaceuticals

Completed

A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's Disease (VIBRANT-HD)

Early Manifest Huntington Disease

Canada, Germany, France, Spain, Hungary
Pfizer

Completed

Multiple Escalating Oral Doses Study of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effect of Multiple Doses of LOXO-305 on the Pharmacokinetics of Single Oral Doses of CYP1A2, CYP2C9, CYP2C19 Substrates in Healthy Participants

Healthy

United States
Amgen

Completed

Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin

Healthy Volunteers

United States
Jiangsu Carephar Pharmaceutical Co., Ltd.

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics of Oral Doses of H008

Erosive Esophagitis

United States

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