Search clinical trials for: organ preservation

Total 60385 results

Tongji Hospital

Not yet recruiting

A Study of Cadonilimab（AK104）Combined With Standard Treatment for Function Preservation in Urinary System Tumors

Urinary System Tumor
Leslie Ballas

Not yet recruiting

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

Muscle-Invasive Bladder Carcinoma | Tumor

United States
Pei-Rong Ding
Fujian Cancer Hospital; Shantou Central Hospital; Liaoning Tumor Hospital & Institute and other collaborators

Recruiting

Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

Rectal Neoplasms

China
National Cancer Institute (NCI)

Not yet recruiting

A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer

Colorectal Cancer | Gastroesophageal Cancer

United States
Fudan University
Shanghai Zhongshan Hospital; RenJi Hospital; First Hospital of China Medical... and other collaborators

Not yet recruiting

Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study

Rectal Cancer | RECTAL NEOPLASMS
University of Colorado, Denver

Recruiting

Testicular Tissue Cryopreservation (TTC) (TTC)

Fertility Issues

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Fertility Preservation and Pregnancy and Offspring Health Outcomes in Female Cancer

Cancer | Fertility Issues

China
Fudan University

Recruiting

DV Combined With Toripalimab for Renal Preservation in Solitary Kidney or Renal Insufficiency or Bilateral Multiple UTUC

Renal Insufficiency | Solitary Kidney | Upper Urinary Tract Urothelial Carcinoma

China
Ruijin Hospital

Not yet recruiting

An Organ Preservation Strategies After Chemoradiotherapy Combined With Immunotherapy for Esophageal Cancer (PALACE3). (PALACE3)

Esophageal Cancer
Tampere University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Recruiting

Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer (NORPPA-1)

Rectal Cancer | Rectal Adenocarcinoma

Finland, Estonia
Tongji Hospital
Zhejiang Cancer Hospital; Xiangya Hospital of Central South University; Beijing... and other collaborators

Not yet recruiting

Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer

Cervical Cancer | Fertility Preservation | Radical Hysterectomy | Neoadjuvant Chemoimmunotherapy

China
Tongji Hospital
Zhejiang Cancer Hospital; Xiangya Hospital of Central South University; Beijing... and other collaborators

Not yet recruiting

Neoadjuvant Chemotherapy Plus Camrelizumab for FIGO Stage IB1 Cervical Cancer

Cervical Cancer | Fertility Preservation | Neoadjuvant Chemoimmunotherapy

China
Alp Sener

Not yet recruiting

Evaluation of Thiosulfate Enhanced Organ Preservation Solution in Kidney Transplantation

Renal Transplant | Kidney Transplant
34 Lives, PBC
University of Miami; University of Wisconsin, Madison; MOUNT SINAI HOSPITAL; Indiana...

Recruiting

A Central Preservation and Assessment Service to Optimize Donor Kidney Allocation (OPTIMAL)

Organ Preservation

United States
Tanta University

Recruiting

Excision Versus Preservation of Spermatic Cord Lipoma Detected During Subinguinal Varicocelectomy

Male Infertility

Egypt
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France; National Cancer Institute, France

Not yet recruiting

Personalized Medicine in Early Stage Colorectal Cancer: Organ Preservation and Immune Benefit (COLOSAVE)

Colorectal Cancer

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Transgender Caregivers' and Patients' Representations of Parenthood as Part of a Fertility Preservation Pathway (TransFert)

Fertility Issues | Transgenderism

France
Assistance Publique - Hôpitaux de Paris

Recruiting

Study of the Prevalence of Endometriosis and Adenomyosis (PrevADEOSE)

Elective Fertility Preservation

France
Peking University Cancer Hospital & Institute

Recruiting

Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer

Rectal Cancer

China
University of Florida

Not yet recruiting

Assessment of Decision Tool to Select Women for Gynecologic Sparing Radical Cystectomy

Urothelial Carcinoma Bladder
University of Leipzig
University of Kiel; University of Cologne; University of Jena; Technical University... and other collaborators

Not yet recruiting

European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] (ELOS)

Laryngeal Cancer | Squamous Cell Carcinoma of Head and Neck | Laryngeal Neoplasms | Squamous Cell Carcinoma of the Larynx | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Laryngectomy; Status | Squamous Cell Carcinoma of Larynx | Squamous Cell Carcinoma of the Larynx Stage... and other conditions
Fundación Santiago Dexeus Font
Organon

Recruiting

Comparison of Sequential CFA vs CFA +rFSH for Elective Fertility Preservation. (2-Shot)

Fertility

Spain
Centre Hospitalier Universitaire de Nīmes

Recruiting

Ovarian Blockade During Fertility Preservation in Patients With Endometriosis (PFENDO)

Endometriosis

France
Chinese University of Hong Kong

Recruiting

Outcome Evaluation After Fertility Preservation

Cancer | Fertility Issues

Hong Kong
Fudan University
Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Ninth People's Hospital... and other collaborators

Recruiting

Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer

Hypopharyngeal Cancer | Larynx Cancer

China
Cliniques universitaires Saint-Luc- Université...

Recruiting

Unraveling the Klinefelter's Disease Physiopathology (KLINEFELTER)

Infertility, Male | Klinefelter Syndrome

Belgium
Sun Yat-sen University

Recruiting

Treating Muscle-invasive Bladder Cancer With A Non-surgical Method Consisting of Anti-PD-1 Therapy and Chemoradiation (BCIRT-01)

Muscle-Invasive Bladder Carcinoma | Radiotherapy | Programmed Cell Death Protein 1 Inhibitor

China
池畔

Not yet recruiting

Organ Preservation Following Enverolimab-based Total Neoadjuvant Therapy for Locally Advanced Very Low Rectal Cancer (TRACE-LE)

Rectal Cancer

China
Peking University People's Hospital
Peking Union Medical College Hospital; Peking University Third Hospital; Tongji... and other collaborators

Recruiting

Fertility-sparing Therapy for Patients With Stage IA Endometrial Cancer

Endometrial Neoplasms | Carcinoma, Endometrioid | Fertility Preservation | Endometrial Neoplasm Malignant Stage I | Endometrial Neoplasm Malignant

China
Osaka University

Recruiting

A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer (AMBITION)

Rectal Cancer

Japan
Fundación de Investigación Biomédica - Hospital...
Hospital Universitario La Fe; Hospital Alemão Oswaldo Cruz; Complejo Hospitalario...

Recruiting

Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment (LORENA)

Rectal Cancer | Rectum Neoplasm

Spain
Washington University School of Medicine
National Cancer Institute (NCI)

Not yet recruiting

A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia

Endometrial Hyperplasia | Grade 1 Endometrial Cancer

United States
University Health Network, Toronto
Medical University of Vienna; University of California, San Francisco; Vanderbilt... and other collaborators

Recruiting

10°C vs 4°C Lung Preservation RCT

Lung Transplant | Organ Preservation

United States, Austria, Switzerland, Canada, Spain
Michael von Wolff
University of Bern

Recruiting

Impact of Gonadotoxic Therapies on Fertility (FertiTOX)

Cancer | Fertility Issues | Effects of Immunotherapy | Toxicity Due to Chemotherapy | Toxicity Due to Radiotherapy | Fertility Preservation

Switzerland
Kyoto University Hospital
Merck Sharp & Dohme LLC; Astellas Pharma Inc; University of Tsukuba; Kobe City... and other collaborators

Recruiting

Pembrolizumab and EV With Radiation Therapy for MIBC Patients (PEVRAD)

Bladder Cancer

Japan
University of Pittsburgh

Recruiting

Ovarian Tissue Cryopreservation for Fertility Preservation

Autoimmune Diseases | Cancer

United States
University of Pittsburgh

Recruiting

Ovarian Tissue Cryopreservation in the Setting of Gender-affirming Therapy

Gender Dysphoria | Transgender

United States
Stanford University

Recruiting

The Stanford Egg Freezing Study

Fertility Issues | Reproductive Issues

United States
Fondazione del Piemonte per l'Oncologia

Recruiting

Robotic Hemi-Prostatectomy With Urethral Preservation in Low and Intermediate Risk Monolateral Prostate Cancer (RETURN)

Prostate Cancer

Italy
University of Pittsburgh

Recruiting

Testicular Tissue Cryopreservation in the Setting of Gender-Affirming Therapy

Gender Dysphoria | Transgender

United States
Washington University School of Medicine
Novo Nordisk A/S

Not yet recruiting

Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia

Endometrial Hyperplasia

United States
The Netherlands Cancer Institute
Catharina Ziekenhuis Eindhoven; ZonMw: The Netherlands Organisation for Health...

Recruiting

Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision (OPAXX)

Quality of Life | Rectal Cancer | Organ Preservation | Locally Advanced Rectal Carcinoma

Netherlands
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Organ Preservation With Durvalumab-based Immunotherapy in Combination With Chemoradiation as Definitive Therapy for Early Stage Esophageal Adenocarcinoma With Indication for Radical Surgery

Esophagus Adenocarcinoma

Germany
University Medical Center Groningen

Recruiting

Long-term Outcomes After Prolonged Dual Hypothermic Oxygenated Machine Perfusion of Donor Livers (DHOPEPROLONG) (DHOPEPROLONG)

Liver Transplantation

Netherlands
National Cancer Center Hospital East
Japan Agency for Medical Research and Development

Recruiting

Total Neoadjuvant Therapy of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer (ENSEMBLE) (ENSEMBLE)

Locally Advanced Rectal Cancer

Japan
Massachusetts General Hospital
C2i Genomics; Spier Family Foundation

Not yet recruiting

ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer

Rectal Cancer | Non Metastatic Rectal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation (JANUS)

Stage III Rectal Cancer AJCC v8 | Stage II Rectal Cancer AJCC v8 | Locally Advanced Rectal Carcinoma

United States, Puerto Rico
National Institute of Arthritis and Musculoskeletal...

Recruiting

Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires

Systemic Lupus Erythematosus (Sle) | Primary Ovarian Insufficiency (Poi)

United States
Shanghai Zhongshan Hospital

Recruiting

Organ Preservation Strategy of Total Neoadjuvant Chemoradiotherapy for Low Rectal Carcinoma (OP-TNT)

Rectal Cancer

China
Hadassah Medical Organization

Recruiting

Follicular FSH Serum Level as a Predictor of an Oocyte Yield and Quality in Fertility Preservation Cycles for Women With a Compromised Ovarian Reserve

Fertility Issues

Israel

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