Search clinical trials for: pharmacodynamic effects, safety, healthy subjects,

Total 41603 results

Forma Therapeutics, Inc.
Medpace, Inc.

Completed

A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

Healthy Volunteers | Sickle Cell Disease

United States
Fulcrum Therapeutics

Completed

Safety, Tolerability and Pharmacokinetics of FTX-6058

Sickle Cell Disease | Healthy Adult Subjects

United States
GlaxoSmithKline

Completed

A Study To Investigate The Metabolism Of GW876008 In Smokers Compared To Non-Smokers.

Healthy Subjects

United States
University of Illinois at Chicago

Completed

Retrospective/Prospective Study of Pediatric Surgical Patients

Pediatric Robotic Surgery

United States
University of Pittsburgh
U.S. Department of Education

Completed

Promoting Health in People With Fibromyalgia

Fibromyalgia

United States
3M

Completed

Adhesive Tape Trauma Evaluation of a New Gentle Tape in Healthy Infant Subjects

Skin (FLACC Scores of Test Subjects) After Tape Removal

United States
Lehigh University

Enrolling by invitation

Task Switching Between Target Templates During Visual Search in Healthy Adults

Healthy

United States
Juvenile Bipolar Research Foundation

Terminated

Intranasal Ketamine In the Treatment of Pediatric Bipolar Disorder (IKBP)

Bipolar Disorder

United States
Nachum Soroker, MD
Ben-Gurion University of the Negev

Completed

Characteristics of Balance Control to Unexpected Loss of Balance During Standing and Walking in Post-stroke Individuals

Stroke

Israel
Biogen

Completed

Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers

Healthy Adult Subjects | Healthy Elderly Subjects

United States
Buddhist Tzu Chi General Hospital

Recruiting

Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction

Irritable Bowel Syndrome | Functional Gastrointestinal Disorders | Healthy Subjects | Laryngopharyngeal Reflux

Taiwan
Centre Hospitalier Universitaire Saint Pierre

Unknown

Dynamic Hyperinflation During Maximal Voluntary Ventilation in Healthy Subjects

Dynamic Hyperinflation

Belgium
GlaxoSmithKline

Completed

Clinical and Economic Burden of Patients With Chronic Obstructive Pulmonary Disease in a Medicaid Population

Pulmonary Disease, Chronic Obstructive
Nadia Bouzidi, PhD

Unknown

Coronary Artery Disease: a Case- Control Study

Coronary Artery Disease

Tunisia
Universidade Federal de Sao Carlos
Universidade Metodista de Piracicaba

Completed

Effects of a Pectoralis Minor Muscle Stretching Protocol (PMISP)

Shoulder Pain

Brazil
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Phase I Single- and Multiple- Ascending Dose and Food Effect Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-7535 in Healthy Subjects

Healthy Subjects
Emergo Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Norketotifen in Healthy Subjects

Healthy Subjects

United States
Eisai Inc.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2027 in Healthy Subjects

Healthy Subjects

United States
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
Azidus Brasil

Completed

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Filgrastim (G-CSF)Produced by Blausiegel Indústria e Comércio Ltda. Compared to Granulokine Produced by Produtos Roche Químicos e Farmacêuticos S/A.

Healthy Subjects

Brazil
Eisai Inc.

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2609 in Healthy Adult Male Japanese and White Subjects

Healthy Subjects

United States
Alexion Pharmaceuticals

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ALXN1007 in Healthy Male and Female Subjects

Healthy Subjects

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016

Healthy Subjects

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose Study of the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of HSD-016

Healthy Subjects

Japan
Biocad

Completed

Comparative Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of Single Intravenous Doses of BCD-148 and Soliris®

Healthy Subjects

Russian Federation
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-389949 in Healthy Subjects

Healthy Subjects

United Kingdom
AstraZeneca

Completed

To Assess Safety, Tolerability and Pharmacodynamics of Intravenous MEDI8111 After Single Ascending Doses.

Healthy Subjects

United Kingdom
Pfizer

Completed

A Single Ascending Dose Study To Evaluate Safety And Pharmacokinetics Of Compound PF-06648671 In Healthy Subjects

Healthy Subjects

Belgium
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effects of Single Ascending Doses of ASP1707 in Healthy Young Japanese Male Subjects

Healthy Subjects

United Kingdom
Xiamen Amoytop Biotech Co., Ltd.

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Assessment of Ypeginterferon Alfa-2a in Healthy Subjects

Healthy Subjects

China
GlaxoSmithKline

Completed

A Study to Investigate the Effects of GW876008 on Brain Activation During Emotional Processing in Healthy Subjects.

Healthy Subjects

United States
Alebund Pty Ltd

Completed

A Pharmacodynamic Effect Study of AP301 in Healthy Volunteers

Healthy Subjects

Australia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

Healthy Subjects

Netherlands
Celgene Corporation

Completed

Effect of UV Exposure on the PD of Multiple Doses of CC-90001 and Pilot Food Effect Study

Healthy Subjects

United States
Eisai Inc.

Completed

A Study to Evaluate the Effects of Diltiazem, a Moderate CYP3A4/A5 Inhibitor, on the Pharmacokinetics and Pharmacodynamics of E5555 and Its Metabolites in Healthy Subjects

Healthy Subjects

Netherlands
Heidelberg University

Completed

Study to Investigate the Pharmacodynamics, Pharmacokinetics and Safety of a Single Oral Repeated Dose of 500 mg Nicotinic Acid as Tablets in Healthy Subjects

Healthy Subjects
GlaxoSmithKline

Completed

GW823296 Repeat Dose Study In Healthy Male And Female Subjects

Healthy Subjects

Australia
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Single Ascending Dose Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HSD-016

Healthy Subjects

United States
Istituto Auxologico Italiano

Recruiting

Mechanical Determinants of Upper Limbs Oscillation During Gait (CLAPENDAS)

Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Amputation | Poststroke/CVA Hemiparesis

Italy
Ascension St. Vincent

Terminated

Discerning Pseudoprogression vs True Tumor Growth in GBMs

Glioblastoma
University of Wisconsin, Madison
Cerveau Technologies, Inc.

Completed

A Longitudinal Evaluation of a Radiotracer for Use in Tau Tracking

Alzheimer Disease | Mild Cognitive Impairment

United States
Savvysherpa, Inc.

Completed

Data Acquisition to Model Glycemic Response (SDI)

Healthy

United States
Pfizer

Completed

A Phase 1 Study To Characterize The Safety, Tolerability, PK And PK Of Repeat Doses Of PF-06648671 In Healthy Adults And Healthy Elderly Subjects

Healthy Adult Subjects and Healthy Elderly Subjects

Belgium
Trinomab Biotech Co., Ltd.
TIGERMED AUSTRALIA PTY LIMITED

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TNM002 in Healthy Adults

Healthy Adult Subjects

Australia
Ahn-Gook Pharmaceuticals Co.,Ltd

Unknown

Investigate a Pharmacodynamics Between S-pantoprazole 10, 20, 40mg and Pantoprazole 20, 40mg in Healthy Male Subjects (AGSPT_PD)

Healthy Male Subjects
Ono Pharma USA Inc

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ONO-6950 in Healthy Adult Subjects

Healthy Adult Subjects

United States
Enzene Biosciences Ltd.
Alkem Laboratories Ltd

Recruiting

Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers

Healthy Male Subjects

Bulgaria, Poland
AstraZeneca

Completed

A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects

Healthy Subjects | Pharmacodynamics

United Kingdom
Pfizer

Completed

Glasdegib Renal Impairment Study

Renal Impairment

United States
Universidad de Murcia

Completed

Circadian System Heritability Assessed in Free Living Conditions (MTR)

Healthy

Spain

3

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