Search clinical trials for: pharmacodynamics (PD)

Total 7675 results

Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease

Idiopathic Parkinson's Disease

United States, Canada, Czechia, Germany, Israel, Italy, Poland, Serbia
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A 12-week Randomized Study to Evaluate Oral Istradefylline in Subjects With Moderate to Severe Parkinson's Disease (KW-6002)

Idiopathic Parkinson's Disease

United States, Canada, Czechia, Germany, Israel, Italy, Poland, Serbia
Jiangsu vcare pharmaceutical technology co., LTD

Completed

Pharmacokinetics and Pharmacodynamics of Vicagrel in Healthy Adult Subjects of Different CYP2C19

Healthy Subjects | PK/PD

China
23andMe, Inc.
Michael J. Fox Foundation for Parkinson's Research; The Parkinson's Institute

Completed

Web-based Genetic Research on Parkinson's Disease

Parkinson's Disease

United States
Charitable Union for the Research and Education...

Active, not recruiting

The Impact of Prednisone on Semen Parameters and Pregnancy Rates Post Vasectomy Reversal

Vasectomy Reversal

United States
Baylor Research Institute

Completed

Virtual Reality and tACS for Performance Enhancement

Law Enforcement Officers

United States
University Hospital, Montpellier

Completed

Impact of Immune Checkpoint Inhibitor Therapy on Type 2 Inflammation (ImmunEO)

Patients Recieving Anti-PD-1 or Anti-PD-L1 Immunotherapies

France
Charite University, Berlin, Germany

Completed

Sildenafil for Treatment of Digital Ulcers in Patients With Systemic Sclerosis (Sildenafil)

Active Digital Ulcers

Germany
LEO Pharma

Completed

Non-interventional Study of Long-term Treatment of Psoriasis With Calcipotriol Plus Betamethasone in Gel Formulation

Plaque Psoriasis | Psoriasis Vulgaris

Germany
AryoGen Pharmed Co.

Completed

Pharmacokinetic, Safety and Tolerability Study of Altebrel in Healthy Male Subjects

Bioequivalence | Phase 1

Iran, Islamic Republic of
Cinnagen

Completed

A Study Of CinnoRA (Adalimumab-CinnaGen) And Adalimumab (Humira) In Healthy Subjects

Bioequivalence | Phase 1

Iran, Islamic Republic of
China Meitan General Hospital
Marino Biotechnology Co., Ltd.

Unknown

Chimeric Switch Receptor Modified T Cells for Patients With PD-L1+ Recurrent or Metastatic Malignant Tumors

Recurrent PD-L1+ Malignant Tumors | Metastatic PD-L1+ Malignant Tumors

China
Samsung Medical Center

Unknown

Phase IV Study to Evaluate the Efficacy and Safety of Mircera in PD

PD

Korea, Republic of
Wuxi People's Hospital

Recruiting

Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours

Cancer | PD-L1 Gene Mutation

China
Luzerner Kantonsspital

Not yet recruiting

OPU-LUX: Virtual Reality for Pain and Anxiety Management During Oocyte Pick-up (OPU-LUX)

Pain, Postoperative | IVF

Switzerland
Regeneron Pharmaceuticals

Terminated

Study of ImmunoPet Imaging of PD-L1 in Tumors Using 89Zr-DFO-REGN3504 in Adult Participants With Advanced PD-L1 Positive Malignancies

Advanced PD-L1 Positive Malignancies

United States
Merck Sharp & Dohme LLC

Recruiting

Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)

Non-small Cell Lung Cancer | Solid Tumors | Programmed Cell Death-1 (PD1, PD-1) | Programmed Cell Death 1 Ligand 1(PDL1, PD-L1) | Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)

Japan
Guohui Li

Recruiting

Multi-Centre, Prospective, Non-Interventional Study to Intensively Monitor the Safety of Sintilimab in Clinical Practice Among Chinese Patients

PD-1 | Immune Related Adverse Events

China
University Medical Center Groningen

Active, not recruiting

MPDL3280A-imaging-IST-UMCG

Locally Advanced or Metastatic Solid Tumors Irrespective of PD-L1 Expression

Netherlands
Shanghai International Medical Center

Unknown

PD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor (Lung, Liver and Stomach)

Advanced Solid Tumor | PD-1 Antibody | CAR-T Cells

China
The Second Affiliated Hospital of Harbin Medical...

Unknown

Application Contract Management Mode in Maintaining PD Fluid Balance (ACMMPDFB)

Contract Management PD
Ruhr University of Bochum

Unknown

Comparison of Two Endoscopically Placed Nasojejunal Probes

Investigation Time

Germany
Hadassah Medical Organization

Recruiting

Adjustment of Aminoglycoside Dosing Based on Peak Serum Concentration and Bacterial Minimal Inhibitory Concentration

Aminoglycoside Dosing Based on PK/PD Characteristics

Israel
Genzyme, a Sanofi Company
Diacrin/Genzyme Corporation LLC

Completed

Phase 2, Double-blind, Randomized, Controlled Multi-center Clinical Trial of the Safety and Efficacy of Transplanted Fetal Porcine Cells in Patients With Parkinson's Disease.

Parkinson's Disease

United States
Ningbo Cancer Hospital

Unknown

PD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor

Advanced Malignancies | PD-1 Antibody | CAR-T Cells

China
Noscira SA

Completed

Safety Study of a Glycogen Synthase Kinase 3 (GSK3) Inhibitor in Patients With Alzheimer´s Disease

Alzheimer´s Disease

Germany
Gilead Sciences
Nimbus Apollo

Completed

Study to Evaluate the Pharmacodynamic Effects of a Single Oral Dose of GS-0976 (NDI-010976) in Healthy Adult Subjects

PD Effects of GS-0976 (NDI-010976) on Fractional DNL

United States
Foundation for Innovative New Diagnostics, Switzerland
Universidad Peruana Cayetano Heredia; Burnet Institute; National Institute for... and other collaborators

Completed

Clinical Evaluation of the Truenat Point-of-care Tuberculosis Diagnostic Test

Tuberculosis, Pulmonary

Ethiopia, India
Agenus Inc.

Completed

AGEN1884, an Anti-CTLA-4 Human Monoclonal Antibody in Subjects With Advanced or Refractory Cancer and Who Have Progressed With PD-1/PD-L1 Inhibitor as Their Most Recent Therapy

Advanced Solid Cancers | Advanced Solid Cancers Refractory to PD-1

United States
Sharp HealthCare

No longer available

A Single Patient IND for PD-0325901

Prior Treatment With PD-0325901 With Ongoing Clinical Response

United States
University of Padova

Recruiting

More Than Body Appearance (MBA) Intervention

Body Image

Italy
Sofia Pavanello
Mibelle AG

Completed

Effects of Monarda Didyma Extract Supplementation on Biological Ageing (EMODISU)

Aging

Italy
University of Padova

Completed

Factor XIII and Other Biomarkers in ST Segment Elevation Myocardial Infarction (eXIST)

Coronary Microvascular Disease | Factor XIII Deficiency | ST-Elevation Myocardial Infarction | Myocardial Haemorrhage

Italy
University of Padova

Completed

Functional and Radiographic Outcomes of Hallux Valgus Correction by Mini-invasive Surgery With Reverdin-Isham Percutaneous Osteotomy (MISHV)

Hallux Valgus

Italy
University of Padova

Completed

CHOKing Prevention Project (CHOP)

Attitudes | Health Knowledge | Practice

Italy
Azienda Ospedaliera di Padova

Completed

The Use of Dexmedetomidine for EEG Sedation in Children With Behavioural Disorders

Behavior Disorders | Procedural Sedation

Italy
Istituto Oncologico Veneto IRCCS
Janssen Diagnostics, LLC

Unknown

Circulating Melanoma Cells in Metastatic Patients Treated With Selective BRAF Inhibitors (CMCBRAF)

Metastatic Melanoma

Italy
University of Padova, School of Dental Medicine

Completed

Prospective Clinical Evaluation of Periodontal Response to Different Prosthetic Margin Design

Gingival Recession | Gingival Bleeding | Gingival Disease

Italy
University of Padova

Terminated

Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis

Cirrhosis | Ascites | Nosocomial Spontaneous Bacterial Peritonitis

Italy
University of Padova

Unknown

Ketamine in Bariatric Surgery

Morbid Obesity

Italy
University of Padova

Completed

Effects of Tracheal Intubation on Ventilation With a Laryngeal Mask During Percutaneous Dilatation Tracheostomy

Neurological Diseases, Heart or Respiratory Failure, | Sepsis, Trauma.

Italy
University of Padova
Department of Ophthalmology, Conegliano Hospital, Treviso, Italy

Unknown

Photodynamic Therapy Combined With Bevacizumab vs Bevacizumab Alone for Neovascular Age-Related Macular Degeneration (ARMAST)

Neovascular Age-Related Macular Degeneration

Italy
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors (SKYSCRAPER-11)

PD-L1-selected Solid Tumors

Korea, Republic of, United States, Spain, Taiwan, Turkey, Greece, Canada, Croatia, Serbia, Mexico, Cyprus, Georgia
Hoffmann-La Roche

Completed

A Study on Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL)

Lymphocytic Leukemia, Chronic

Germany
Beijing Friendship Hospital

Not yet recruiting

PD-1 Antibody Improve Mixed Chimerism (HLH)

PD-1 Antibody | Mixed Chimerism

China
Gianni Soraru
Mario Negri Institute for Pharmacological Research

Recruiting

A Placebo-controlled Study of Clenbuterol in Spinal and Bulbar Muscular Atrophy (BetaSBMA)

Spinal and Bulbar Muscular Atrophy

Italy
University of Padova
University Hospital Padova

Recruiting

Correct Timing of Head Imaging in Trauma (CT-HIT)

Craniocerebral Trauma | Platelet Aggregation Inhibitors

Italy
University of Padova

Enrolling by invitation

Clinical and Surgical Outcomes of Total Thyroidectomy in Basedow's Disease: the Effect of Lugol Solution (BALU)

Basedow Disease

Italy
Azienda Ospedaliera di Padova

Completed

Virtual Reality for Pediatric Palliative Care Team (PPCVR)

Occupational Stress

Italy
University of Padova

Active, not recruiting

Psychosocial Blended Group Intervention RCT

Social Isolation

Italy

Search clinical trials for: pharmacodynamics (PD)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Nigeria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations