Search clinical trials for: schizophrenia, BDNF, DNA methylation, histone modification

Total 10672 results

Assiut University

Recruiting

Immunohistochemical Evaluation of DNA Methylation and Histone Modification in H. Pylori Associated Gastric Carcinoma

Gastric Carcinoma

Egypt
Bristlecone Health, Inc.
University of Minnesota

Completed

Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation

Metabolic Syndrome | Mild Cognitive Impairment

United States
Chang Gung Memorial Hospital

Completed

Epigenetic Regulation of BDNF in Major Depression

Major Depressive Disorder

Taiwan
Chang Gung Memorial Hospital

Completed

Epigenetic Regulation of BDNF in Schizophrenia

BDNF, DNA Methylation, Suicide, Drug Responses.

Taiwan
The University of Queensland

Recruiting

A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients (BEAT-BK)

Kidney Transplant Infection | Kidney Transplant Failure and Rejection | BK Viremia

Australia
Medical College of Wisconsin

Recruiting

Venetoclax to Augment Epigenetic Modification and Chemotherapy

Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory

United States
National Research Centre, Egypt

Not yet recruiting

Omics-based Predictors of NAFLD/Potential NASH

Non-Alcoholic Fatty Liver Disease | Non Alcoholic Steatohepatitis

Egypt
Federal State Budgetary Scientific Institution...
State Scientific Centre of Coloproctology, Russian Federation; Ministry of... and other collaborators

Recruiting

Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse

Functional Constipation | Pelvic Floor Prolapse | Rectocele

Russian Federation
National Cancer Institute (NCI)

Completed

Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins

Lymphoma | Lymphoid Hyperplasia

United States
Sangamo Therapeutics

Active, not recruiting

Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX (LTFU)

Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II

United States
University Hospital, Basel, Switzerland
Friedrich Miescher Institute for Biomedical Research (FMI)

Completed

Human Sperm Epigenetics in Embryonic Development. (EPI)

Male Infertility | Epigenetic Disorder

Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members

Fatigue | Overweight | Lynch Syndrome | Chronic Lymphocytic Leukemia | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Breast Carcinoma | Cancer Survivor | Ovarian Carcinoma | Health Status Unknown | Body Mass Index 25 or Greater

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Understanding Post-translational Modifications to Circulating Histones Via Mass Spectrometry in Pregnant Women Developing Pre-eclampsia: A Retrospective Study (GHISPE)

Pregnancy Related | Pre-Eclampsia

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Vorinostat and Combination Chemotherapy Before Donor Stem Cell Transplantation for the Treatment of Relapsed Aggressive B-cell or T-cell Non-Hodgkin Lymphoma

Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Aggressive Non-Hodgkin Lymphoma | Recurrent Burkitt Lymphoma | Recurrent Transformed B-Cell Non-Hodgkin Lymphoma

United States
Theodore R. Brown, MD MPH
Astellas Pharma Inc

Completed

Study of Behavioral Modification Program and Mirabegron to Improve Urinary Urgency in Multiple Sclerosis (MIRROR)

Multiple Sclerosis

United States
National Cancer Institute (NCI)

Terminated

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Carcinoma, Non-Small-Cell Lung | Non-Small Cell Lung Cancer | Lung Cancer | Carcinoma, Esophageal | Malignant Pleural Mesotheliomas

United States
Sangamo Therapeutics

Terminated

Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-318 in Subjects With MPS I

MPS I

United States
Sangamo Therapeutics

Terminated

Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-913 in Subjects With MPS II

Mucopolysaccharidosis II | MPS II

United States
Hunan Cancer Hospital

Completed

Circulating Tumor DNA (ctDNA)-Guided Late-Line Treatment in Patients With Late-Stage Breast Cancer (ACTDNAGLT)

Metastatic Breast Cancer | Circulating Tumor DNA | Gene Abnormality
Mayo Clinic
National Cancer Institute (NCI)

Completed

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade... and other conditions

United States
University of Toronto

Active, not recruiting

Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk

Cardiovascular Diseases | Inflammation | Hypertension | Obesity | Diabetes | Metabolic Syndrome | Dyslipidemias | PreDiabetes | NAFLD | Gout | Cardiometabolic Syndrome

Canada
University of Melbourne

Completed

The Effect of Physiotherapy Treatment Following Gynaecological Surgery

Vaginal Hysterectomy | Pelvic Organ Prolapse Vaginal Surgery

Australia
Samsung Medical Center

Completed

Clinical Relevance of DNMT and HDAC Gene SNP on the Response to Decitabine Therapy for Myelodysplastic Syndrome

Myelodysplastic Syndrome

Korea, Republic of
University of California, San Francisco
Merck Sharp & Dohme LLC; Avon Foundation

Terminated

Reversing Therapy Resistance With Epigenetic-Immune Modification

Breast Neoplasms

United States
University of Toronto
Canadian Diabetes Association; The Physicians' Services Incorporated Foundation and other collaborators

Unknown

Meta-analyses of the Effect of Important Food Sources of Sugars on Cardiometabolic Risk Factors

Hypertension | Cardiovascular Disease | Diabetes | Dyslipidemia | Non-alcoholic Fatty Liver Disease | Prediabetes | Gout | Dysglycemia

Canada
Mayo Clinic
National Cancer Institute (NCI)

Completed

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
National Cancer Institute (NCI)

Completed

Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom... and other conditions

United States
Barretos Cancer Hospital

Completed

Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic Acid (GAMA)

Head and Neck Squamous Cell Carcinoma

Brazil
Assistance Publique - Hôpitaux de Paris

Completed

Presence of Circulating Tumor DNA in Colorectal Cancer (ALGECOLS)

Colorectal Neoplasms

France
University of Pittsburgh
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Further Enhancing Non-pharmacologic Therapy for Incontinence

Urge Urinary Incontinence

United States
University of Aarhus

Completed

Histones and Free-plasma DNA After Cardiac Arrest

Heart Arrest | Hypothermia | Post Cardiac Arrest Syndrome

Denmark
University of Washington
National Cancer Institute (NCI)

Completed

Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Assiut University

Unknown

The Role of Epigenetic Modifications in Autism Spectrum Disorder

Autism Spectrum Disorder
Huazhong University of Science and Technology

Unknown

The Epigenetic Modification in OPRM1 on Postoperative Analgesia and Side Effect Induced by Sufentanil

Epigenetics

China
University of Toronto
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; The Physicians' Services Incorporated Foundation

Unknown

Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases

Cardiovascular Diseases | Stroke | Hypertension | Diabetes Mellitus, Type 2 | Gout | Metabolic Syndrome X

Canada
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canada Research Chairs Endowment... and other collaborators

Unknown

Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease

Hypertension | Obesity | Cardiovascular Disease | Diabetes | Overweight | Metabolic Syndrome | Dyslipidemia | Coronary Heart Disease | Hyperlipidemia | Prediabetes | Gout | Dysglycemia

Canada
University of Toronto
Canadian Institutes of Health Research (CIHR); The Physicians' Services Incorporated... and other collaborators

Unknown

Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk

Hypertension | Obesity | Cardiovascular Disease | Dyslipidemia | Prediabetes | Gout | Non-Alcoholic Fatty Liver Disease | Dysglycemia

Canada
Women and Infants Hospital of Rhode Island
Centers for Disease Control and Prevention

Completed

Clinical Trial of Behavioral Modification to Prevent Congenital Cytomegalovirus (CDC/CMV)

Pregnancy | Cytomegalovirus Infections | Behavior

United States
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canada Research Chairs Endowment... and other collaborators

Unknown

Meta-analyses of Fructose and Cardiometabolic Risk

Hypertension | Obesity | Cardiovascular Disease | Diabetes | Overweight | Metabolic Syndrome | Dyslipidemia | Non-alcoholic Fatty Liver Disease | Prediabetes | Gout | Dysglycemia

Canada
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canada Research Chairs Endowment... and other collaborators

Unknown

Meta-Analyses of the Effect of Vegetable Protein for Animal Protein on Cardiometabolic Risk

Hypertension | Obesity | Cardiovascular Disease | Diabetes | Overweight | Metabolic Syndrome | Dyslipidemia | Kidney Injury | Prediabetes | Gout | Dysglycemia | Kidney Disease | Non-alcoholic Fatty Liver Disease (NAFLD)

Canada
Mirati Therapeutics Inc.

Terminated

Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States, Canada, United Kingdom
National Cancer Institute (NCI)

Completed

Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

Canada
National Cancer Institute (NCI)

Completed

Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Juvenile Myelomonocytic Leukemia | Recurrent Childhood Medulloblastoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Acute Promyelocytic Leukemia (M3) | Childhood Chronic Myelogenous Leukemia | Recurrent Childhood Acute Lymphoblastic... and other conditions

United States
National Cancer Institute (NCI)

Completed

PXD101 in Treating Patients With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma

United States
Pelvic and Sexual Health Institute

Unknown

Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome

Sexual Dysfunction | Interstitial Cystitis | Painful Bladder Syndrome | Bowel Dysfunction | Pelvic Floor; Incompetency | Pelvic Floor; Insufficiency

United States
Unity Health Toronto

Completed

Acute Effect of Nitrate From Natural Dietary Sources on Arterial Stiffness and Blood Pressures in Healthy Individuals (DNAB)

Healthy

Canada
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Nordic MDS Group

Completed

Evaluation of Azacitidine in Transfusion Dependent Patients With Low-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML)

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

Denmark, Norway, Sweden
National Cancer Institute (NCI)

Completed

Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Diffuse Large Cell Lymphoma | Childhood Immunoblastic Large Cell Lymphoma | Childhood Nasal Type Extranodal NK/T-cell Lymphoma | Recurrent Childhood Anaplastic... and other conditions

United States

Search clinical trials for: schizophrenia, BDNF, DNA methylation, histone modification

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