Search clinical trials for: senescence

Total 59 results

Universidade Federal Fluminense

Not yet recruiting

Effects of Royal Jelly Supplementation in Chronic Kidney Disease

Hemodialysis | Kidney Failure, Chronic | Oxidative Stress

Brazil
Northwestern University

Not yet recruiting

Fisetin to Reduce Senescence and Mobility Impairment in PAD (FIRST)

Peripheral Arterial Disease | Peripheral Vascular Diseases | Aging | Walking, Difficulty
National Institute of Medical Sciences and Nutrition...

Not yet recruiting

Adversity and Its Association With the Development and Expression of Rheumatic Diseases (RD)

RhA - Rheumatoid Arthritis
Niguarda Hospital
Istituto di Fisiologia Clinica CNR

Recruiting

Vascular Senescence and Atherosclerotic Plaque Vulnerability (VICTORIA)

Coronary Artery Disease

Italy
Fundación IVI
Instituto Valenciano de Infertilidad, IVI VALENCIA

Recruiting

Impact of IVF Hormonal Therapy on Endometrial Receptivity and Endometrial Senescent Cell Pathological Accumulation (HormoSenoRec)

Endometrial Receptivity

Spain
Patrick Schjelderup
Aarhus University Hospital

Not yet recruiting

Multiparametric MRI in a Prospective Cohort of Living Kidney Donors, Recipients, and Healthy Controls: Correlations With Markers of Renal Function, Fibrosis and Ageing (MpRenal)

Kidney Transplantation | Living Donors | Senescence | Renal Fibrosis | Multiparametric Magnetic Resonance Imaging
Odense University Hospital
Novo Nordisk A/S; Odense Patient Data Explorative Network

Recruiting

Senolytics to Improve Osteoporosis Therapy (SENIOR)

Osteopenia, Osteoporosis

Denmark
IRCCS Azienda Ospedaliera Universitaria San Martino...
AstraZeneca

Recruiting

GLUcose Transport and REnalPROtection in Chronic Kidney Disease (GLUTREPRO)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Disease

Italy
Yonsei University

Recruiting

Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 Diabetes

Diabetes Mellitus | Sodium-Glucose Transporter 2 Inhibitors | Cellular Senescence

Korea, Republic of
VA Office of Research and Development
Baltimore VA Medical Center; South Texas Veterans Health Care System

Not yet recruiting

Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation (MARVEL)

Obesity | Post-COVID Conditions

United States
Assiut University

Not yet recruiting

Cyclin-dependent Kinase Inhibitor 2A (Placental Senescence Marker) on Labor-related Signals

Preterm Labor
Tianjin Medical University

Recruiting

Peripheral Treg Cell Senescence & Serum Total Cholesterol Level

Hypercholesterolemia

China
Cedars-Sinai Medical Center
National Institute on Aging (NIA)

Recruiting

Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects

Obesity | Healthy Lifestyle

United States
University of California, Los Angeles

Recruiting

COMP-4 Supplementation and Brachial Artery FMD

Aging | Endothelial Dysfunction | Senescence

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Nasal Brushing for the Diagnosis and Understanding of Telomeropathies (TELOSTIC)

Telomere Shortening | Telomere Disease

Belgium
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Characterization of the microVAScular Dysfunction in Covid-19 ARDS (VASCOV)

ARDS, Human | COVID-19 Acute Respiratory Distress Syndrome

France
St. Jude Children's Research Hospital
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer

Frailty | Childhood Cancer

United States
University Hospital Tuebingen

Recruiting

Study to Assess Safety and PET Imaging Characteristics of a Novel Senescence-specific Radiotracer [18F]FPyGal (2-[Fluorine-18]Fluoro-3-pyridinyl-β-D-galactopyranoside) (SenPET)

Cancer

Germany
AdventHealth Translational Research Institute

Recruiting

Brown Adipose Tissue as a Therapeutic for the Metabolic and Cardiac Dysfunction With Senescence (BATSR) (BATSR)

Metabolic Diseases

United States
University Medical Center Groningen
Dutch Cancer Society

Recruiting

Senescence and the Early Ageing Phenotype After Chemotherapy for Testicular Cancer: the SEA-CAT Study

Testicular Cancer

Netherlands
University Hospital, Strasbourg, France

Recruiting

Impact of Endothelial and Leukocyte Senescence in Circulatory Shock States (Seneshock)

Cardiovascular Diseases | Shock | Infection

France
Mayo Clinic

Enrolling by invitation

Senescence in Chronic Kidney Disease

Chronic Kidney Disease

United States
Sundeep Khosla, M.D.

Active, not recruiting

Targeting Cellular Senescence With Senolytics to Improve Skeletal Health in Older Humans

Healthy

United States
Montreal Heart Institute

Active, not recruiting

Quercetin in Coronary Artery By-pass Surgery (Q-CABG)

Coronary Artery Disease

Canada
Lewis Lipsitz

Completed

Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease (STAMINA)

Aging

United States
Mayo Clinic

Enrolling by invitation

Cellular Senescence and COVID-19 Long-Hauler Syndrome

SARS-CoV2 Infection

United States
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Completed

Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation (OPTIMAL)

Liver Transplantation | Liver Transplant

United States
University of North Carolina, Chapel Hill
Georgia Institute of Technology; Sapere Bio

Completed

Patterns of Natural Aging and the Role of Senescence Registry

Healthy Aging

United States
Austin V Stone
Brigham and Women's Hospital

Withdrawn

Targeting Senescence to Reduce Osteoarthritis Pain and cartilagE Breakdown (ROPE) (ROPE)

Osteoarthritis, Knee

United States
Vitality in Aging Research Group, Inc.

Withdrawn

VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements

Aging
Memorial Sloan Kettering Cancer Center
Brigham and Women's Hospital; Weill Medical College of Cornell University; The... and other collaborators

Completed

Cognitive Changes Associated With Breast Cancer Treatment

Breast Cancer | Cognitive Side Effects of Cancer Treatments | Stage I, II and III A Breast Cancer

United States
Unity Biotechnology, Inc.

Completed

A Study to Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee

Osteoarthritis, Knee

United States
Centre Oscar Lambret
Institut de Biologie de Lille

Completed

Molecular Mechanisms of Senescence Predisposing to Cancer : Exploratory Analysis on Healthy Tissues (SkinAge).

Sarcoma

France
Central Hospital, Nancy, France

Suspended

PROGENitors, TELomeres and ARTerial Aging (PROGENTELART)

Atherosclerosis of Artery

France
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Vascular Access for Hemodialysis and Inflammation

Vascular Access for Hemodialysis and Inflammation

Italy
Eunice Kennedy Shriver National Institute of Child...

Completed

Epigenetics in the Aging Process

Aging

United States
Unity Biotechnology, Inc.

Terminated

Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo

Knee Osteoarthritis

United States
Unity Biotechnology, Inc.

Completed

A Study of Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Lorenza Scotti

Unknown

Impact of the Comprehensive Geriatric Assessment on the Quality of Life OF Elderly Patients (ONCO-AGING)

Solid Tumor | Elderly Patients | Hematologic Malignancies

Italy
Arbor Life Labs

Completed

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Male Subjects With Hair Loss (REBOOT-MEN)

Androgenetic Alopecia | Androgenic Alopecia | Hair Loss/Baldness | Hair Thinning | Telogen Effluvium | Thinning Hair

United States
Arbor Life Labs

Completed

A Study Evaluating the Hair Regrowth Efficacy and Safety of ALRV5XR in Female Subjects With Hair Loss (REBOOT-WOMEN)

Androgenetic Alopecia | Androgenic Alopecia | Hair Loss/Baldness | Hair Thinning | Telogen Effluvium | Thinning Hair

United States
Unity Biotechnology, Inc.

Completed

A Safety and Tolerability Study of UBX0101 in Patients With Osteoarthritis of the Knee

Osteoarthritis, Knee

United States
Instituto Nacional de Ciencias Medicas y Nutricion...

Suspended

Pyridostigmine as Immunomodulator in People Living With HIV

HIV-1-infection | Immune Deficiency | CD4+ T Lymphocytopenia | Immuno-senescence

Mexico
Smith & Nephew, Inc.

Terminated

A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention (WoundWand)

Lower Leg Wound

France, United Kingdom
Medical University of Vienna
Valneva Austria GmbH

Unknown

Immune Responses After a Booster Immunisation With IXIARO® in Elderly Compared to Young Individuals.

Japanese Encephalitis Vaccine

Austria
Centre d'Alt Rendiment
University of Barcelona; Indena S.p.A; Hospital Sant Joan de Deu

Completed

Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes (CoQ10Sport)

Aging | Oxidative Stress | Coenzyme Q10

Spain
Rush University Medical Center

Completed

Fish Oil for HIV-Related Inflamm-aging and Immune Senescence

HIV Infection

United States
Chandra Duggirala

Unknown

Reversing Epigenetic & Other Markers of Senescence by Transfusing Young Plasma To Older Human Subjects (RESET-YOUTH)

Aging

United States
CHU de Reims

Unknown

Role of Senescence in the Development of Endometrial Cancer

Endometrial Hyperplasia and Endometrial Cancers

France
Hospices Civils de Lyon

Completed

Premature Aging and Type 2 Diabetes Mellitus: an Increased Risk of Cardiomyopathy? (R2D2)

Type 2 Diabetes Mellitus

France

Search clinical trials for: senescence

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