Search clinical trials for: sepsis immunosuppression Treg

Total 4112 results

Southeast University, China

Recruiting

Co-inhibitory Molecules on Treg and miR-155-5p in Patients With Sepsis

28 Day Mortality

China
hemotune AG

Not yet recruiting

First in Human Trial to Assess the Safety & Efficacy of HemoSystem REBOOT in Patients With Sepsis-induced Immunosuppression (RESTORE I)

Septic Shock

Switzerland
Novartis Pharmaceuticals

Recruiting

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (SA-AKI)

Acute Kidney Injury Due to Sepsis

United States, Canada, Turkey, United Kingdom, Thailand
Pneumonia Research Network on Genetic Resistance...
Charite University, Berlin, Germany; University of Leipzig; Jena University Hospital

Recruiting

Study of Progression of Community Acquired Pneumonia in the Hospital in Patients With More Severe Preexisting Diseases and Immunosuppression (PROGRESSCOMORB)

Pneumonia | Sepsis | Shock, Septic

Germany
University of Florida
National Institute of General Medical Sciences (NIGMS)

Recruiting

Pathological Myeloid Activation After Sepsis and Trauma

Sepsis | Trauma Injury | Immunosuppression | Chronic Critical Illness

United States
The University of Queensland

Recruiting

A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients (BEAT-BK)

Kidney Transplant Infection | Kidney Transplant Failure and Rejection | BK Viremia

Australia
Bacchetta, Rosa, MD
Food and Drug Administration (FDA); California Institute for Regenerative Medicine...

Recruiting

CD4^LVFOXP3 in Participants With IPEX

IPEX

United States
University of Kansas Medical Center
University of Kansas

Recruiting

Function of Circulating Exosomes in Sepsis-induced Immunosuppression

Sepsis | Septic Shock | Sepsis Syndrome | Sepsis, Severe | Sepsis Bacterial | Sepsis Bacteremia

United States
Wuhan Union Hospital, China

Recruiting

Immunoinflammatory Regulation of Esketamine in Septic Patients

Sepsis | Inflammatory Response | Immunosuppression | Esketamine

China
Hospices Civils de Lyon

Recruiting

Septic Shock-induced Immunosuppression (IMMUNOSEPSIS 4)

Septic Shock

France
University of Florida
National Institutes of Health (NIH); National Institute on Aging (NIA)

Active, not recruiting

Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty

Sepsis

United States
National Institute of Allergy and Infectious Diseases...
PPD; Rho Federal Systems Division, Inc.; Immune Tolerance Network (ITN)

Terminated

Liver Transplantation With Tregs at UCSF (LITTMUS-UCSF)

Liver Transplant

United States
Banc de Sang i Teixits
Hospital Universitario La Fe; Vall d'Hebron Institute of Oncology

Completed

Virus-specific Activated T Lymphocytes From a Donor in Hematopoietic Progenitor Transplanted Patients

CMV Viremia | Immunosuppression-related Infectious Disease

Spain
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Active, not recruiting

Liver Transplantation With Tregs at MGH (LITTMUS-MGH)

Liver Transplant

United States
Centre Hospitalier Universitaire, Amiens

Withdrawn

Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients (DRUGTOX)

Immunosuppression | Kidney Transplant | Uremic; Toxemia

France
Centre Hospitalier Universitaire de Nice

Withdrawn

Evaluation of Sepsis-induced Immunosuppression Base on QuantiFERON Monitor® in Septic Shock (MONITOR SEPSIS)

Septic Shock
Radboud University Medical Center
UMC Utrecht

Completed

The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells (LPS-BM)

Sepsis, Endotoxemia, Immunosuppression

Netherlands
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Clinical Trials in Organ Transplantation...

Completed

Donor Alloantigen Reactive Tregs (darTregs) for Calcineurin Inhibitor (CNI) Reduction (ARTEMIS)

Liver Transplant Recipient | Living Donor (of the Respective Liver Transplant Recipient)

United States
Hospices Civils de Lyon

Completed

GM-CSF to Decrease ICU Acquired Infections (GRID)

Septic Shock | Severe Sepsis

France
King's College London
King's College Hospital NHS Trust

Terminated

Low-dose IL-2 for Treg Expansion and Tolerance (LITE) (LITE)

Liver Diseases | Transplantation

United Kingdom
Nanjing First Hospital, Nanjing Medical University

Completed

The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis

Sepsis | Enteral Feeding | Immune System Disorder

China
Hospices Civils de Lyon
Sanofi; Bioaster; BioMérieux

Completed

REAnimation Low Immune Status Markers (REALISM)

Septic Shock | Severe Trauma | Severe Burn | Major Surgery

France
Jianfeng Xie

Completed

Dynamic Alterations of Th2/Th1 With New Onset of Community-acquired Severe Sepsis Patients

Sepsis

China
West China Hospital

Completed

Study on the Role of Gamma Delta T Cells in Sepsis Immunosuppression and Its Molecular Mechanism

Sepsis

China
University of Edinburgh
Becton, Dickinson and Company; Technology Strategy Board, United Kingdom

Completed

Immune Failure in Critical Therapy (INFECT) Study (INFECT)

Sepsis | Septic Shock

United Kingdom
Hospices Civils de Lyon

Unknown

Evaluation of Immunosuppression in Septic Shock: Biomarkers and Pharmacological Restoration (IMMUNOSEPSIS) (IMMUNOSEPSIS)

Immunology of Septic Shock

France
Changhai Hospital

Unknown

Expression of TIM-3 on Lymphocytes in Sepsis

Sepsis | Immunosuppression

China
Changhai Hospital

Completed

Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis

Sepsis | Immunosuppression
Hospices Civils de Lyon

Not yet recruiting

Recurrent Campylobacter Bacteraemia in Immunocompromised Patients (CABARET)

Campylobacter Infections

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Characterization of Autoreactive Regulatory and Conventional CD4 T Cells in Recent Onset Type 1 Diabetes and Control Individuals (CARegT1D)

Type 1 Diabetes

France
The Cleveland Clinic

Not yet recruiting

Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator

Shock, Septic
Fondation Hôpital Saint-Joseph

Not yet recruiting

Impact of Performing a Rapid Antibiotic Susceptibility Test on Antibiotic Therapy Adaptation in Adult Patients With Enterobacterales Bacteremia (MHR-Blood)

Bacteremia
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
University of Santiago de Compostela
Hospital Clinico Universitario de Santiago

Not yet recruiting

An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

Bacteremia | Endocarditis

Spain
Hospital Italiano de Buenos Aires

Not yet recruiting

Mortality of MBL-producing Enterobacteriaceae Bacteremias With the Combined Use of Ceftazidime-avibactam and Aztreonam vs. Other Active Antibiotics. A Multicenter Target Trial Emulation.

Bacteremia
Indonesia University

Not yet recruiting

Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm Babies

Sepsis, Neonatal
IRCCS San Raffaele

Recruiting

INfectious DIsease REgistry BIObank (INDI-REBIO)

Central Nervous System Infections | Infective Endocarditis | Vertebral Osteomyelitis | Bone and Joint Infections | Bloodstream Infections | Endovascular Infections | CIED-related Infections

Italy
Xuzhou Medical University

Not yet recruiting

Safety and Efficacy of Treg Cell in the Treatment of GVHD

GVHD
St George's, University of London
MU-JHU CARE; Biomedical Research and Training Institute, Zimbabwe

Recruiting

Using Machine Learning to Model Early-onset Neonatal Sepsis Risk in Uganda and Zimbabwe (NeoRisk)

Neonatal Sepsis

Uganda, United Kingdom
Chunling Jiang

Not yet recruiting

Organ Dysfunction Change in Acute Necrotizing Pancreatitis Patients With Sepsis After Open Necrosectomy

Necrotizing Pancreatitis
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Indian Council of Medical Research
King George's Medical University; Lady Hardinge Medical College; King Edward... and other collaborators

Not yet recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates (SAUNA)

Sepsis | Preterm Birth | Preterm Premature Rupture of Membrane | PROM, Preterm (Pregnancy) | Early-Onset Neonatal Sepsis

India
Preeclampsia Foundation

Recruiting

The Preeclampsia Registry (TPR)

Toxemia | Eclampsia | Preeclampsia | HELLP Syndrome | Hypertensive Disorder of Pregnancy

United States
Shen Lei

Not yet recruiting

Comparison of Nafamostat and Unfractionated Heparin in RRT for Sepsis Associated AKI

Sepsis

China
Uppsala University Hospital

Not yet recruiting

Mechanisms of Acute Kidney Injury in Severe Infections (PET-AKI)

Sepsis | AKI - Acute Kidney Injury | Positron Emission Tomography (PET)
Egymedicalpedia

Not yet recruiting

Effect of Early Administration of Albumin 20% Versus Crystalloid

Septic Shock

Egypt
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

Bacteriophage Therapy for Difficult-to-treat Infections: the Implementation of a Multidisciplinary Phage Task Force (PHAGEFORCE)

Sepsis | Chronic Rhinosinusitis (Diagnosis) | Hidradenitis Suppurativa | Pulmonary Infection | Musculoskeletal Infection

Belgium
Guy's and St Thomas' NHS Foundation Trust
Pontificia Universidad Catolica de Chile; University of Rotterdam, The Netherlands

Not yet recruiting

UK ANDROMEDA-Shock-2 RCT

Septic Shock
Hospital de Clinicas de Porto Alegre
Hospital Moinhos de Vento; Irmandade Santa Casa de Misericórdia de Porto Alegre

Recruiting

Tunneled Peripherally Inserted Central Catheter (PICC) in Adult Patients and Associated Outcomes

Deep Vein Thrombosis | Occlusion | Dislodged Catheter | CLABSI - Central Line Associated Bloodstream Infection | Catheter Rupture | Catheter (Other); Complications

Brazil

Search clinical trials for: sepsis immunosuppression Treg

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