Search clinical trials for: severe COPD

Total 12355 results

AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Healthy
Pulmonx Corporation

Recruiting

Zephyr Valve Japan Post-Marketing Surveillance

Emphysema | COPD | Severe Emphysema

Japan
Alexis FERRE

Recruiting

Patients With Severe Acute Exacerbation of COPD Ans Admitted in ICU Register. (COPDregister)

COPD Exacerbation

France
Ferran Morell

Not yet recruiting

Severe Prospective Observational COPD Catalonia (SPOCCAT)

Severe Chronic Obstructive Pulmonary Disease
Amgen

Recruiting

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Sjögren's Syndrome (SS)

United States
University Hospital, Clermont-Ferrand

Not yet recruiting

Study of the Cytokine Response During Exercise Dyspnea in Patients With Chronic Obstructive Pulmonary Disease (COPD). Effect of Body Composition (CYTODINE)

Dyspnea | Chronic Obstructive Pulmonary Disease Severe

France
Hospital Universitario 12 de Octubre

Recruiting

Customized Masks in Non-Invasive Mechanical Ventilation

Non Invasive Ventilation | Ventilatory Failure | COPD, Severe Early-Onset | Als

Spain
University Hospital, Grenoble

Not yet recruiting

Oral Citrulline Supplementation in COPD Patients With Malnutrition (CITRUS)

Malnutrition | Chronic Obstructive Pulmonary Disease Severe
Northumbria Healthcare NHS Foundation Trust
GlaxoSmithKline; Newcastle University; Chiesi UK

Recruiting

Eosinopenia in Severe COPD Exacerbation (A-TREC)

Chronic Obstructive Pulmonary Disease

United Kingdom
University Hospital, Limoges

Recruiting

Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves (REPEAT)

COPD

France
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetic Characteristics, Safety, Tolerability, and Preliminary Efficacy of 9MW1911 in Patients With Chronic Obstructive Pulmonary Disease (COPD).

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

China
Shanghai Chest Hospital

Not yet recruiting

A Multi-center RCT to Evaluate Subsegmental BTVA Treatment for Severe Emphysema (BTVA)

Severe Emphysema
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

Evaluation of 611 in Chinese Adults With Moderate to Severe Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

China
Lithuanian University of Health Sciences

Recruiting

Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease

Cardiovascular Diseases | Quality of Life | Chronic Obstructive Pulmonary Disease Moderate | Chronic Obstructive Pulmonary Disease Severe

Lithuania
Pulmonx Corporation

Recruiting

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema (CONVERT_II)

Emphysema or COPD | Emphysema, Pulmonary

Spain, Germany, Italy, Australia
Lady Reading Hospital, Pakistan
Pakistan Chest Society, Pakistan

Recruiting

Clopidogrel for the Prevention of Exacerbations in Severe COPD (CLOPEX)

COPD | COPD Exacerbation Acute

Pakistan
Food and Health Bureau, Hong Kong
Hospital Authority, Hong Kong

Not yet recruiting

A Decision Aid on End-of-life Care for Patients With Advanced COPD and Their Family

Chronic Obstructive Pulmonary Disease Severe
Apreo Health, Inc.

Recruiting

Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema (BREATHE-2)

Emphysema or COPD

United Kingdom, Austria, Netherlands
The First Affiliated Hospital with Nanjing Medical...
Novlead Inc.

Recruiting

A Clinical Study of Inhaled Nitric Oxide in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (NOVEL)

Chronic Obstructive Pulmonary Disease

China
Apreo Health, Inc.

Recruiting

First in Human Study to Assess an Implant to Treat Severe Emphysema (BREATHE-1)

Emphysema or COPD

Australia
Assistance Publique - Hôpitaux de Paris

Recruiting

Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (ERASE PH-COPD)

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

France
Franciscus Gasthuis
Teva Pharmaceuticals USA

Recruiting

Expertise Asthma COPD Program With Digital Support (EXACT@home)

Asthma

Netherlands
Saglik Bilimleri Universitesi

Recruiting

Effect of Home Based Pulmonary Rehabilitation on Exacerbation and Hospital Admission in Severe COPD

COPD Exacerbation

Turkey
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France; Xenios AG

Recruiting

CO2 Removal in Severe Acute exacerbatIons of Chronic Obstructive Lung Diseases (CORAIL)

COPD Acute Exacerbation

France
Randall Debattista
University of Malta, Faculty of Health Sciences

Not yet recruiting

Effect of NMES on Quadriceps Muscle Strength and Endurance in Patients With COPD (NMES)

Chronic Obstructive Pulmonary Disease Moderate | Acute Exacerbation of COPD | Chronic Obstructive Pulmonary Disease Severe
Hasselt University

Recruiting

Functional Strength Training and Neuromuscular Electrical Stimulation in Severe Acute Exacerbations of COPD

Acute Exacerbation of COPD | Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Belgium
Assistance Publique - Hôpitaux de Paris
BioMérieux

Recruiting

Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter Trial (MULTI-EXA)

Acute Exacerbation of COPD

France
University of Parma
Chiesi Farmaceutici S.p.A.

Not yet recruiting

Effect of BDP/Formoterol/G on Cough Efficacy in Moderate to Severe COPD Patients (EFFICACE) (EFFICACE)

COPD, Chronic Obstructive Pulmonary Disease

Italy
Hopital Foch
Air Liquide SA

Recruiting

Exploration of the VOLATOLOM in the Stable Severe COPD (Chronic Obstructive Pulmonary Disease) (VOC-BPCO)

Chronic Obstructive Pulmonary Disease Severe

France
Vastra Gotaland Region

Recruiting

Multidisciplinary Management of Severe COPD

Copd | COPD Exacerbation

Sweden
Li Xuyan

Recruiting

ECCO2R in the Treatment of Acute Exacerbation of COPD With Severe Hypercapnia

Lung Diseases, Obstructive

China
Hopital Foch
Air Liquide SA

Recruiting

Volatolom Variation in Severe COPD During Hospitalization for Exacerbation and After Hospitalization (VOC-BPCO-Exa) (VOC-BPCO-Exa)

Chronic Obstructive Pulmonary Disease Exacerbation

France
ShiYue Li
AstraZeneca

Not yet recruiting

The Effects of Inhaled Budesonide-formoterol-glycopyrronium in Moderate-to-severe COPD (OCT)

Pulmonary Disease, Chronic Obstructive

China
University of Catanzaro
Azienda Sanitaria Provinciale Di Catanzaro; Azienda Ospedaliera Universitaria...

Recruiting

Immune Checkpoints in COPD (CP-COPD)

Asthma | Lung Cancer | Copd | Severe ARDS

Italy
Versailles Hospital

Recruiting

Comparison of Corticosteroids vs Placebo on Duration of Ventilatory Support During Severe Acute Exacerbations of COPD Patients in the ICU (Corticop)

Chronic Obstructive Pulmonary Disease

France
Johns Hopkins University
Patient-Centered Outcomes Research Institute

Recruiting

Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) (RELIANCE)

Chronic Bronchitis | Chronic Obstructive Pulmonary Disease Severe

United States
Xenios AG
Winicker Norimed GmbH

Recruiting

Early Extubation by ECCO2R Compared to IMV in Patients With Severe Acute Exacerbation of COPD (X-COPD)

COPD Exacerbation

Germany
Institut d'Investigacions Biomèdiques August Pi...
Hospital Clinic of Barcelona

Enrolling by invitation

K-HEALTH in AIR - Barcelona Pilot - Cohort

COPD | Severe Asthma

Spain
AstraZeneca

Active, not recruiting

An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD. (CRESCENDO)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Denmark, Italy, United Kingdom, Canada, Germany, Turkey, Argentina, South Africa, Spain, Poland, Bulgaria, Mexico, Netherlands
AstraZeneca

Active, not recruiting

Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations (RESOLUTE)

Chronic Obstructive Pulmonary Disease

United States, Austria, Canada, Denmark, Germany, Italy, Spain, United Kingdom, Belgium, Vietnam, Brazil, Hungary, Philippines, China, Korea, Republic of, Argentina, Australia, Poland, Turkey, Japan, Greece, Netherlands, Czechia, Mexico, Bulgar... and more
AstraZeneca

Active, not recruiting

Real-world, 52-week Prospective Study to Capture the Reasons for Switch to Triple Combination Therapy, Assess the Clinical and Patient Reported Outcomes in Adults With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Treated With Trixeo Aerosphere™ in Routine Care Settings in Greece (TRIAENA)

Pulmonary Disease, Chronic Obstructive (COPD)

Greece
AstraZeneca

Completed

A Study to Assess the Safety of Budesonide/Glycopyrronium/Formoterol Fumarate With the Hydrofluoroolefin Propellant in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada, Germany, Argentina, Bulgaria, Poland, Turkey, Mexico, United Kingdom
Cliniques universitaires Saint-Luc- Université...

Completed

Breathing Control Exercises in Patients With Chronic Obstructive Pulmonary Disease.

Severe Chronic Obstructive Pulmonary Disease

Belgium
Karaganda Medical University

Completed

Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD (COPD)

Chronic Obstructive Pulmonary Disease | Chronic Obstructive Pulmonary Disease Moderate | Chronic Obstructive Pulmonary Disease Severe

Kazakhstan
Guy's and St Thomas' NHS Foundation Trust

Suspended

Efficacy of an Advanced Auto-titrating NIV in COPD

Chronic Obstructive Pulmonary Disease Severe

United Kingdom
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Chronic Obstructive Pulmonary Disease

Greece, Belgium, Spain, Argentina, Hungary, South Africa, United Kingdom, France, Latvia, Germany, Netherlands, Russian Federation, Ukraine, United States, Australia, Brazil, Bulgaria, Canada, Chile, Colombia, Czechia, Lithuania, Me... and more
Pulmonx Corporation

Active, not recruiting

Fissure Closure With the AeriSeal System for CONVERTing Collateral Ventilation Status (CONVERT) (CONVERT)

Emphysema | COPD | Severe Emphysema

United Kingdom, France, Netherlands, Germany, Australia, Italy, Switzerland
McGill University Health Centre/Research Institute...
University of Calgary

Suspended

Home Non-Invasive Ventilation Targeting Expiratory Flow Limitation in Severe Hypercapnic COPD.

COPD

Canada
University of California, San Francisco
The Taimaka Project

Terminated

Azithromycin for Severe Acute Malnutrition in CMAM, Nigeria

Severe Acute Malnutrition

Nigeria
Sanofi
Regeneron Pharmaceuticals

Completed

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation (BOREAS)

Chronic Obstructive Pulmonary Disease

Spain, Argentina, China, Mexico, Canada, Ukraine, Israel, Italy, Czechia, Korea, Republic of, Bulgaria, Chile, Denmark, Finland, Germany, Hungary, Japan, Poland, Romania, Russian Federation, Slovakia, Sweden, Turkey, United States

Search clinical trials for: severe COPD

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