Search clinical trials for: sirolimus

Total 1210 results

Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Microsampling Assays for Immunosuppressive Drugs in Children (MAIDEN)

Immunosuppression

United States
Katarzyna Kotulska

Recruiting

Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants (ViRap)

Tuberous Sclerosis Complex

Poland
Luzerner Kantonsspital

Recruiting

SIROOP Registry - A Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated With SIROlimus Or Paclitaxel Eluting Balloon Catheters (SIROOP)

Coronary Artery Disease | Coronary Disease | Angina, Stable | Angina Pectoris | Coronary Arteriosclerosis | Angina, Unstable | Coronary Artery Calcification | Stent Thrombosis | Coronary Restenosis | Stable Chronic Angina

Switzerland
Acotec Scientific Co., Ltd

Recruiting

Acoart SCB SFA: Sirolimus Coated Balloon Catheter in the Treatment of Femoropopliteal Artery Stenosis

Peripheral Artery Disease

China
National Cancer Institute (NCI)

Recruiting

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Hematologic Neoplasms

United States
Beijing Tiantan Hospital

Recruiting

Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial (DREAM-PRIDE)

Stroke | Intracranial Atherosclerotic Disease

China
University of Chicago

Recruiting

Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis

Pulmonary Fibrosis | COVID-19 Pneumonia | Long COVID

United States
Haukeland University Hospital

Recruiting

Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

Thyroid-Associated Ophthalmopathy

Norway
National University of Ireland, Galway, Ireland

Recruiting

The PIONEER-IV Study is Comparing Clinical Outcomes Between Angiography-derived Physiology Guidance to Usual Care in an All-comers PCI Population With Unrestrictive Use of the HT Supreme Sirolimus-eluting Stent (PIONEER-IV)

Coronary Artery Disease

Belgium, Netherlands, Ireland, United Kingdom, Spain
Children's Hospital of Fudan University

Recruiting

Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular Anomalies

Kaposiform Hemangioendothelioma | Tufted Angioma | Superficial Vascular Anomalies | Superficial Lymphatic Malformations

China
Acotec Scientific Co., Ltd
Shanghai Zhongshan Hospital

Recruiting

ACOART SCB BIF: Treatment of Coronary Bifurcation Lesion by Sirolimus Coated Balloon vs Paclitaxel Coated Balloon

Coronary Bifurcation Lesions

China
Shenzhen Salubris Pharmaceuticals Co., Ltd.

Recruiting

Sirolimus DEB in Coronary Bifurcation Lesions

Coronary Bifurcation Lesions

China
Fondazione Ricerca e Innovazione Cardiovascolare...

Recruiting

Sirolimus-coated Balloon Versus Drug-eluting Stent in Native Coronary Vessels (TRANSFORM II)

Coronary Artery Disease | Coronary Artery Stenosis

Spain, Netherlands, Italy, France, Bangladesh
Palvella Therapeutics, Inc.

Recruiting

CODY: A Study Evaluating The Safety And Efficacy Of QTORIN 3.9% Sirolimus Topical Gel For The Prevention Of Basal Cell Carcinomas (BCCs) In Patients With Gorlin Syndrome

BCCs in Gorlin Syndrome Patients

United States, United Kingdom
Peking Union Medical College Hospital
North China Pharmaceutical Group Corporation

Not yet recruiting

Sirolimus in Treatment of Proteinuric Flares of Lupus Nephritis

Lupus Nephritis | Immunosuppression | Effect of Drug
University of Birmingham
IMPACT (funded by NHS Blood & Transplant, Anthony Nolan and Leukaemia UK)

Recruiting

Methods of T Cell Depletion Trial (MoTD) (MoTD)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Non Hodgkin Lymphoma | Chronic Myelogenous Leukemia

United Kingdom
Medical University of South Carolina

Recruiting

Weekly Sirolimus Therapy

Lymphatic Malformation | Venous Malformation

United States
Biotyx Medical (Shenzhen) Co., Ltd.

Recruiting

IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease (GENIUS)

Critical Limb Ischemia (CLI)

China
University of Kansas Medical Center
The Perron Institute

Recruiting

Phase III Trial of Sirolimus in IBM

Inclusion Body Myositis

United States, Australia
Jena University Hospital
Concept Medical Inc.; CoreLab Black Forest; Center for Clinical Studies, University... and other collaborators

Recruiting

Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease (LIMES)

Peripheral Artery Disease

Germany, Austria
The University of Texas Health Science Center at...
National Institute on Aging (NIA); The Claude D. Pepper Older Americans Independence...

Recruiting

Effect of mTOR Inhibition & Other Metabolism Modulating Interventions on the Elderly [SubStudy Rapa & cMRI to Evaluate Cardiac Function] (mTOR)

Aging

United States
Peking Union Medical College

Not yet recruiting

Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway

Breast Cancer

China
State University of New York - Upstate Medical...

Not yet recruiting

Sirolimus Treatment Of Patients With SLE (STOPSLE)

Lupus Erythematosus, Systemic
Chong Kun Dang Pharmaceutical

Not yet recruiting

Efficacy and Safety of Sirolimus Plus CNI Compared With MMF Plus CNI in ABO-i Kidney Transplant Recipients.

Kidney Transplantation

Korea, Republic of
Biotronik AG

Recruiting

Resorbable Magnesium Scaffolds Registry

Coronary Artery Disease

Germany
Instituto Nacional de Cardiologia Ignacio Chavez

Recruiting

Randomized Trial Comparing Two Sirolimus-Eluting Stents in Diabetes Mellitus (INC-DM)

Coronary Artery Disease | Diabetes Mellitus | Acute Coronary Syndrome

Mexico
The University of Texas Health Science Center at...

Recruiting

Rapamycin - Effects on Alzheimer's and Cognitive Health (REACH)

Alzheimer Disease | Mild Cognitive Impairment

United States
IHF GmbH - Institut für Herzinfarktforschung

Recruiting

Post-Market Registry to Evaluate the Safety and Efficacy of the The SUPRAFLEX CRUZ™ Sirolimus Eluting Coronary Stent System in the Treatment of an Octo- and Nonagenerian All-Comer Patient Cohort With Coronary Artery Disease - the Cruz Senior Study

Coronary Disease

Germany
University of Pisa

Not yet recruiting

Sirolimus for Graves' Orbitopathy (GO) (SIRGO)

Graves Ophthalmopathy

Italy
Joost Daemen
Horizon 2020 - European Commission; REVA Medical, Inc.

Recruiting

FANTOM ENCORE Sirolimus-eluting Bioresorbable Scaffold for Treatment of De-novo CAD: the ENCORE-I Study

Percutaneous Coronary Intervention | Tomography, Optical Coherence | Myocardial Revascularization

Netherlands, Belgium
Chinese SLE Treatment And Research Group
Beijing Municipal Science & Technology Commission; North China Pharmaceutical...

Recruiting

Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus (SIRIUS)

Systemic Lupus Erythematosus

China
Concept Medical Inc.

Recruiting

ABLUMINUS DES BTK Registry - FIM

Atherosclerosis | Peripheral Artery Disease | Arterial Disease of Legs

Singapore
National Cancer Institute (NCI)

Recruiting

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States, Puerto Rico, Israel
Concept Medical Inc.

Recruiting

SirolimUs CoaTed Balloon for The TrEatment of Below The Knee Arterial Disease (FUTURE-BTK)

Atherosclerosis | Peripheral Artery Disease | Arterial Disease of Legs

Singapore, Korea, Republic of, Taiwan
Concept Medical Inc.

Recruiting

Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease (FUTURE-SFA)

Atherosclerosis | Peripheral Artery Disease | Arterial Disease

Singapore, Korea, Republic of, Taiwan
Emory University
PeachBowl LegACy Fund

Recruiting

Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors (AflacST1903)

Solid Tumor

United States
Mercator MedSystems, Inc.

Not yet recruiting

Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee (TANGO-3)

Peripheral Artery Disease | Critical Limb Ischemia
Shanghai Children's Medical Center

Not yet recruiting

SCMC Trial on KHE With KMP (V.2020) (SCMC-KK2020)

Kaposiform Hemangioendothelioma (KHE) With Kasabach-Merritt Phenomenon (KMP)

China
Singapore General Hospital
National University Hospital, Singapore; Sengkang General Hospital

Recruiting

Sirolimus Coated Angioplasty Versus Plain Balloon Angioplasty (IMPRESSION)

End Stage Renal Failure on Dialysis | Arteriovenous Graft Occlusion

Singapore
Shanghai Children's Medical Center

Not yet recruiting

Sirolimus in the Treatment for Infantile Hepatic Hemangioendothelioma(IEEH) (PRL-SRL-IHHE)

Hemangioendothelioma of Liver

China
Prevail Therapeutics
Eli Lilly and Company

Recruiting

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN) (PROCLAIM)

Frontotemporal Dementia

United States, Australia, Belgium, Spain, United Kingdom, France
National University of Ireland, Galway, Ireland

Recruiting

Multivessel TALENT

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Coronary Artery Disease | Coronary Disease | Arterial Occlusive Diseases

Ireland
Rapamycin Holdings, Inc. dba Emtora Biosciences
National Cancer Institute (NCI)

Recruiting

Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention

Non-muscle Invasive Bladder Cancer

United States
Clinica San Gaudenzio

Recruiting

Sirolimus Eluting Balloon Utilization for Treatment of Vasculogenic Erectile Dysfunction (SUASION)

Erectile Dysfunction

Italy
Università degli Studi di Ferrara
Azienda Ospedaliero, Universitaria Pisana; Rare Partners srl Impresa Sociale; Azienda Ospedaliero, Universitaria Meyer

Recruiting

Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP) (THALA-RAP)

Beta-Thalassemia

Italy
Nils Kucher

Recruiting

Major Adverse Limb Events in Patients With Femoro-popliteal and Below-the-knee Peripheral Arterial Disease Treated With Either Sirolimus-coated Balloon or Standard Uncoated Balloon Angioplasty

Peripheral Arterial Disease

Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Metastatic Sarcoma | Resectable Sarcoma | Recurrent Sarcoma

United States
Shanghai Bio-heart Biological Technology Co., Ltd.
CCRF Inc., Beijing, China

Not yet recruiting

A Registry Trial of The Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System

Coronary Artery Disease

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Allogeneic Hematopoietic Stem Cell Transplant Recipient

United States
Nemours Children's Clinic

Recruiting

Topical Rapamycin/Sirolimus for Complicated Vascular Anomalies and Other Susceptible Lesions (NOVA)

Vascular Anomaly

United States

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