Search clinical trials for: sodium zirconium cyclosilicate

Total 10086 results

Leiden University Medical Center
AstraZeneca

Not yet recruiting

Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4 (LIBRAL)

Diet Modification | Chronic Kidney Disease | Hyperkalemia | Sodium Zirconium Cyclosilicate
AstraZeneca

Recruiting

A National, Multicenter, Prospective, Observational Study to Assess Patient Characteristics, Treatment Algorithms and Disease Management of Hyperkalaemia Patients With Chronic Kidney Disease or Under Dialysis or With Heart Failure, Treated With Sodium Zirconium Cyclosilicate in Greece (SHIELD)

Hyperkalaemia

Greece
Alexandria University

Recruiting

SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients

Hyperkalemia

Egypt
AstraZeneca

Recruiting

Continuing Sodium Zirconium Cyclosilicate (SZC) After Discharge Study (CONTINUITY)

Chronic Kidney Disease | Hyperkalaemia

United Kingdom, Spain, Belgium, Italy, Netherlands, France, Germany
St George's, University of London

Recruiting

Lokelma for RAAS Maximisation in CKD & Heart Failure. (LIFT)

Chronic Kidney Diseases | Heart Failure With Reduced Ejection Fraction | Hyperkalemia | ACE Inhibitor Induced Hyperkalaemia | Mineralocorticoid Resistant Hyperkalemia

United Kingdom
Michael Fu
Göteborg University; AstraZeneca

Recruiting

OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure (OPRA-HF)

Heart Failure | Hyperkalemia

Sweden
University of California, Irvine

Recruiting

Comparison of Potassium Binders in the ER (KBindER)

Acute Hyperkalemia | Oral Potassium Binders

United States
AstraZeneca

Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia (PEDZ-K)

Hyperkalaemia

China, Germany, United States, Ukraine, Spain, Japan, United Kingdom, Canada, Poland, Romania, Russian Federation, Brazil
AstraZeneca

Active, not recruiting

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone (REALIZE-K)

Heart Failure With Reduced Ejection Fraction | Hyperkalaemia

United States, Spain, Canada, Brazil, Hungary, Czechia, Ukraine, Poland, United Kingdom
AstraZeneca

Terminated

Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

Hyperkalemia

United States, Italy, Spain, Taiwan, Thailand, Vietnam, Russian Federation, Canada, Hungary, Mexico, China, Austria, Turkey, Brazil, Germany, Poland, Czechia, United Kingdom, Bulgaria, Slovakia, Peru, Ukraine, Japan, Argentina, Malaysia, ...
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
AstraZeneca

Terminated

A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia (STABILIZE-CKD)

Renal Insufficiency, Chronic | Hyperkalemia

United States, Italy, Spain, Thailand, Vietnam, Turkey, Canada, Philippines, China, Malaysia, Taiwan, Brazil, Japan, Bulgaria, Russian Federation, Poland, Argentina, Mexico, Ukraine, India, Puerto Rico
AstraZeneca

Active, not recruiting

A Multicenter, Prospective, Non-interventional Cohort Study to Evaluate the Safety and Treatment Pattern of Sodium Zirconium Cyclosilicate for Hyperkalaemia Management in Real World Practice in China (ACTUALIZE)

Hyperkalaemia

China
AstraZeneca

Terminated

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease (NEUTRALIZE)

Chronic Kidney Disease | Metabolic Acidosis | Hyperkalaemia

United States, Puerto Rico
Barts & The London NHS Trust

Terminated

The ORTIZ Study: Optimising RASi Therapy With SZC (ORTIZ)

Diabetes Mellitus, Type 2 | CKD | Hyperkalemia

United Kingdom
Karolinska Institutet
AstraZeneca

Completed

Healthy Diet Rich in Potassium to Chronic Kidney Disease With Sodium Zirconium Cyclosilicate: A Feasibility Study (HELPFUL)

Chronic Kidney Disease Stage 5 | Hyperkalemia | Chronic Kidney Disease stage4

Sweden
AstraZeneca

Completed

Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects (DIALIZE China)

Hyperkalemia

China
AstraZeneca

Terminated

Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia (GRAZE)

Hyperkalaemia

United States
AstraZeneca

Completed

A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia. (HARMONIZE Asia)

Hyperkalemia

China
Guangdong Provincial People's Hospital

Completed

Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy (SZC)

Hyperparathyroidism, Secondary | Hyperkalemia | Sodium Zirconium Cyclosilicate
AstraZeneca

Terminated

Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure (PRIORITIZE HF)

Heart Failure

United States, Canada, Brazil, Slovakia, Hungary, Romania, Poland, Russian Federation, Bulgaria
Brigham and Women's Hospital

Unknown

Potassium Binder in CKD Patients (With Hyperkalemia) (DiPo Trial)

Chronic Kidney Diseases | Hyperkalemia

United States
AstraZeneca

Completed

A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia (HARMONIZE GL)

Hyperkalemia

Korea, Republic of, Taiwan, Russian Federation, Japan
AstraZeneca

Completed

Open-label Safety of Sodium Zirconium Cyclosilicate for up to 12 Months in Japanese Subjects With Hyperkalemia

Hyperkalemia

Japan
AstraZeneca

Completed

A Study to Test Whether ZS (Sodium Zirconium Cyclosilicate) Can Reduce the Incidence of Increased Blood Potassium Levels Among Dialized Patients. (DIALIZE)

Hyperkalemia

United States, United Kingdom, Russian Federation, Japan
AstraZeneca

Completed

A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 (ENERGIZE)

Hyperkalemia

United States, Russian Federation, Italy, Denmark
Steno Diabetes Center Copenhagen
Zealand University Hospital; AstraZeneca

Unknown

The Effect of Sodium Zirconium Cyclosilicate on Albuminuria in Patients With Type 2 Diabetes and Hyperkalemia (ZIRCUS)

Type 2 Diabetes Mellitus With Kidney Complications

Denmark
AstraZeneca

Completed

ZS Ph2/3 Dose-response Study in Japan

Hyperkalemia

Japan
ZS Pharma, Inc.

Completed

Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia.

Hyperkalemia

United States, South Africa, Australia
ZS Pharma, Inc.

Completed

Open-label Safety & Efficacy of ZS (Sodium Zirconium Cyclosilicate)10g qd to Extend Study ZS-004 in Hyperkalemia.

Hyperkalemia

United States, South Africa, Australia
ZS Pharma, Inc.

Completed

Open-label Safety and Efficacy of Sodium Zirconium Cyclosilicate for up to 12 Months

Hyperkalemia

United States, Germany, Australia, Netherlands, South Africa, Romania, United Kingdom
AstraZeneca

Completed

A Safety and Pharmacodynamic Study of Healthy Chinese Subjects Administered Sodium Zirconium Cyclosilicate (ZS)

Hyperkalemia

Hong Kong
Peking University First Hospital

Recruiting

The Effect of Potassium Lowering Drugs on Cardiac Electrical Stability in Hemodialysis Patients (ART Study)

Cardiac Arrhythmia | Potassium Imbalance | Dialysis; Complications

China
TC Erciyes University

Recruiting

Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing

Endodontic Disease

Turkey
Tongji Hospital

Not yet recruiting

Effect of Amobarbital Sodium Combined With Low-dose Propofol on Hemodynamics During Induction and Perioperative Adverse Reactions

Hemodynamics Instability | Amobarbital Sodium
Novartis Pharmaceuticals

Not yet recruiting

A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Mixed Dyslipidemia | Primary Hypercholesterolemia
Nordsjaellands Hospital

Recruiting

Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block

Anesthesia, Local | Surgery | Brachial Plexus Block | Nerve Block | Forearm Fracture

Denmark
Nordsjaellands Hospital

Recruiting

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Colles' Fracture | Fracture Dislocation | Distal Radius Fractures | Lidocaine | Ropivacaine | Closed Reduction of Fracture and Application of Plaster Cast

Denmark
Wilfrid Laurier University
Natural Sciences and Engineering Research Council, Canada

Not yet recruiting

Effect of Oral Lactate Ingestion on Appetite Regulation

Appetitive Behavior
HALEON

Not yet recruiting

A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain

Pain
Modern Biosciences Ltd

Not yet recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
HALEON

Recruiting

A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Dentin Sensitivity

Canada
Teoxane SA

Not yet recruiting

RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)

Pain | Aging

United States
Helwan University

Recruiting

Role of Calcium Chloride Injection in Alleviating Atrial Fibrillation Post CABG

Atrial Fibrillation

Egypt
Amany Ahmed Eissa

Recruiting

The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients: Randomized Controlled Trial.

Erector Spinae Plane Block | Bariatric Surgery | Super Obese Patients

Egypt
Capital Medical University

Not yet recruiting

Multiple Electrolytes Injection (II) and Normal Saline on Hyperchloremia in Severe Hemorrhagic Stroke (MERIT)

Hemorrhagic Stroke | Critical Care | Hyperchloremia

China
Galderma R&D

Not yet recruiting

Comparing Pain, Safety and Effectiveness of Restylane Skinboosters Vital Lido and Vital Without Lido in Dorsal Hand

Skin Aging of Dorsal Hands

China
Post Graduate Institute of Medical Education and...

Not yet recruiting

MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin (SHIELD)

Non-Alcoholic Fatty Liver Disease | Hepatic Steato-Fibrosis

India
Kasr El Aini Hospital

Recruiting

Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response

To Measure Systolic Blood Pressure Postintubation

Egypt
Katelyn Atkins

Not yet recruiting

Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography

Oligometastatic Disease

United States

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