Search clinical trials for: trough concentrations

Total 652 results

Rennes University Hospital

Recruiting

Observational Study Comparing the Efficacy of Ganciclovir as a Function of Blood Exposure to the Drug During a Curative or Preemptive Treatment (GANEX)

Solid Organ Transplantation

France
University Hospital, Ghent
KU Leuven

Completed

A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated

Psoriasis

Belgium
University Hospital, Basel, Switzerland

Completed

Characterization of Adalimumab Concentrations in Pediatric Patients With Inflammatory Rheumatic Disease With and Without Methotrexate (ADA in PiRD)

Rheumatic Diseases

Switzerland, Germany
Novartis Pharmaceuticals

Terminated

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations (MACS1148)

CML | Philadelphia Chromosome Positive (Ph+) | Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels

United States
Sheba Medical Center

Completed

Effect of Vitamin D on Everolimus Trough Concentrations Among Heart Transplanted Patients

Vitamin D Deficiency

Israel
People's Hospital of Zhengzhou University

Completed

Loading Regimen，Serum Trough Concentrations，Efficacy and Safety in Pneumonia Patients With Gram-positive Infections

Pneumonia Gram-Positive Bacterial
Universitaire Ziekenhuizen KU Leuven

Unknown

Adalimumab Trough Concentrations in Crohn's Disease: A Pilot Pharmacokinetic Study

Crohn's Disease

Belgium
Bristol-Myers Squibb

Completed

Study to Assess Steady-State Trough Concentrations, Safety, and Immunogenicity of Abatacept After Subcutaneous (SC) Administration to Subjects With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
Innovative Medical

Completed

Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients: Trough Drug Effects

Cataract

United States
West China Hospital

Recruiting

Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients

Lymphatic Malformation

China
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy

Irreversible Pulpitis | Extremely Deep Caries | Partial Pulpotomy

India
University of Roma La Sapienza

Recruiting

Use of 'Mechanical Power' as a Predictor of Increased Serum and Pulmonary Proinflammatory Cytokine Concentrations in Patients With Acute Hypoxemic Respiratory Failure: A Prospective Observational Study

Mechanical Power

Italy
Phathom Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Vonoprazan Concentrations in Breast Milk of Healthy Lactating Women Receiving Vonoprazan 20 mg Once Daily

Helicobacter Pylori Infection | Heartburn | Erosive Esophagitis | Symptomatic Nonerosive Gasroesophageal Reflux Disease

United States
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
Johns Hopkins University
ON Foundation

Not yet recruiting

Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes

Rotator Cuff Tears

United States
China Medical University, China

Recruiting

Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia

Oxygenation Index

China
AbbVie

Recruiting

A Study to Assess the Concentrations of Risankizumab in the Breast Milk of Adult Lactating Women With Inflammatory Bowel Disease

Inflammatory Bowel Disease

Israel
University of Aarhus
Aarhus University Hospital

Not yet recruiting

Effects of Exogenous Ketone Ester Supplementation on 3-hydroxybutyrate Concentrations in Human Cerebrospinal Fluid (KetoBrain)

Ketosis

Denmark
Jagiellonian University

Recruiting

Activity of Chronic Inflammation in PCOS

Polycystic Ovary Syndrome

Poland
Radboud University Medical Center
Maastricht University Medical Center

Recruiting

TREAT Study - Improving the Interpretation of Troponin Concentrations Following Exercise and Their Clinical Significance (TREAT)

Coronary Artery Disease

Netherlands
University Clinical Centre of Republic of Srpska

Recruiting

Population Pharmacokinetic Model of Amikacin and Vancomycin in Critically Ill Patients

Sepsis

Bosnia and Herzegovina
First Affiliated Hospital of Chengdu Medical College

Recruiting

Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization

Primary Aldosteronism | Resistant Hypertension | Secondary Hypertension | Secondary Hypertension to Endocrine Disorders

China
Ziekenhuis Oost-Limburg

Not yet recruiting

The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Block (ROADS)

Anesthesia | Hallux Valgus
Chulalongkorn University

Recruiting

Low Versus Standard Concentrations and Volumes Local Anesthetics Boluses for Continuous Adductor Canal Block Under Ultrasound-guidance in Total Knee Arthroplasty

Knee Arthropathy

Thailand
University Health Network, Toronto

Not yet recruiting

A Study to Evaluate Zanubrutinib and Tislelizumab in Progressive Lymphoma Post CAR-T (ZanTisle)

Large B-cell Lymphoma
Nutricia Research

Recruiting

Amino Acid Concentrations in Serum After Intake of Different Protein Sources

Postprandial Amino Acid Concentrations in Healthy Adults

Netherlands
Aaron Cook
Cumberland Pharmaceuticals

Recruiting

Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With Subarachnoid Hemorrhage

Subarachnoid Hemorrhage, Aneurysmal

United States
University Hospital, Montpellier
IntegraGen SA

Not yet recruiting

Genomic Study of Cutis Tricolor (Cutis Tricolor)

Pigmentary; Dermatosis
University Hospital Center of Martinique
University Hospital, Limoges; Reims University Hospital; BioGaia AB; Regional Health... and other collaborators

Not yet recruiting

Effects of Probiotic Oral Intake on Plasma Chlordecone (Kepone) Concentrations in Individuals Environmentally Exposed to Pesticide in Martinique. (CHLOR-DETOX)

Chlordecone (Kepone) Toxicity

Martinique
University Hospital for Infectious Diseases, Croatia
Croatian Science Foundation

Recruiting

The Role of Immune Semaphorins in Steatotic Liver Disease and Sepsis (SepsisFAT)

Sepsis | Immune Response | Steatosis of Liver

Croatia
Anebulo Pharmaceuticals

Recruiting

Observational Study of THC Concentrations in Acute Cannabinoid Intoxication

Acute Cannabinoid Intoxication

United States
China Medical University, China

Recruiting

Effects of Different Oxygen Concentrations on Pulmonary Complications in Patients Undergoing Radical Resection of Esophageal Cancer (DOICA-E)

Atelectasis, Postoperative

China
University Hospital, Caen

Not yet recruiting

Relation Between Psychoactive Drugs Overdosage and Severity of Falls in Elderly People (MEDIFALL)

Fall
Cari Health Inc.
Samplimy Medical AB

Recruiting

Assessment of Methadone Dose Taken Using Electrochemistry

Pain, Chronic | Metabolism Medication Toxicity | Methadone Toxicity | Methadone Overdose | Drug Metabolism, Poor, CYP2D6-Related

United States
National Nutrition and Food Technology Institute

Not yet recruiting

The Effects of an Anti-inflammatory Diet With or Without Curcumin Supplementation on Anthropometric Measurements, Concentrations of Thyroid Hormones, Anti-TPO, and Systemic Inflammation in Plasma and NFK-B in Peripheral Blood Mononuclear Cells in Patients With Hashimato

Hypothyroidism | Thyroid Diseases | Hashimoto Disease

Iran, Islamic Republic of
AuriGen Medical Ltd

Recruiting

Zenith LAA Occlusion System

Stroke | Atrial Fibrillation | Left Atrial Appendage

New Zealand
Karl Landsteiner University of Health Sciences

Recruiting

Prediction of Propofol Effect Compartment Concentrations (Propo2022)

Analysis of Anaesthesia Depth

Austria
Ilker Ital
Abant Izzet Baysal University

Recruiting

Evaluation of the Effectiviness of Two Different Bupivacaine Concentrations of the Pericapsular Nerve Group (PENG) Block (PENG)

Postoperative Pain | Hip Fractures

Turkey
University of Minnesota

Recruiting

To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation

Central Airway Obstruction

United States
Baylor College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Baylor Infant and Toddler Biomarker of Nutrition Study (BITBONS)

Healthy Diet | Healthy Nutrition

United States
Jagiellonian University

Recruiting

Subclinical Hypothyroidism and Chronic Inflammation in PCOS

Subclinical hypothyroïdism | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries | Hypothalamic-Pituitary-Gonadal Axis Dysfunction

Poland
Armed Forces Institute of Dentistry, Pakistan

Recruiting

Different Concentrations of Sodium Hypochlorite Affecting Post-endodontic Pain (NaOCl)

Post Operative Pain

Pakistan
Emory University
National Cancer Institute (NCI); Verastem, Inc.

Recruiting

Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastoma

Glioblastoma | Recurrent Glioblastoma

United States
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Royal Children's Hospital; Monash Health; Royal...

Not yet recruiting

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) (VANCAPP)

Infections | Sepsis | Bacteremia

Australia
Alexandria University

Recruiting

Periocular Rejuvenation by Topical Hyaluronic Acid Nano Particles

Wrinkle | Tear Trough Eyelid Deformity | Dark Eyelids

Egypt
Imperial College London
Merck Sharp & Dohme LLC

Not yet recruiting

ATP and P2X3 Receptor in Chronic Cough

Cough
Alexandria University

Recruiting

Effect of Obesity on Cyclosporine Blood Trough Level in Nephrotic Syndrome Patients

Nephrotic Syndrome

Egypt
Tanta University

Not yet recruiting

The Analgesic Efficacy of Two Bupivacaine Concentrations for Combined Ilioinguinal and Iliohypogastric Nerve Block in Postherniorrhaphy Pain

Hernia, Inguinal
Hospices Civils de Lyon

Recruiting

Hypovitaminosis C Prevalence and Risk Factors in an Acute Geriatric Unit (HYPO-VIT-C)

Deficiency, Vitamin C

France
University Hospital, Clermont-Ferrand

Recruiting

Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects (RMN-UNIBI)

Bipolar Disorder Type II | Mood Depressive Disorder

France

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