Search clinical trials for: trough levels

Total 3781 results

Singapore General Hospital

Active, not recruiting

Efficacy of Achieving Early Target Trough Levels of Tacrolimus Using CYP3A5 Guided Dosing Versus Weight-based Dosing in a Multi-ethnic Population of Kidney Transplant Recipients in Singapore

Kidney Transplant Rejection | Kidney Transplant; Complications

Singapore
University Hospital, Ghent
KU Leuven

Completed

A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated

Psoriasis

Belgium
Radboud University Medical Center
Erasmus Medical Center

Active, not recruiting

Lengthening Adalimumab Dosing Interval in Quiescent Crohn's Disease Patients (LADI)

Crohn Disease | Crohn Disease in Remission

Netherlands
Hospital San Carlos, Madrid
Merck Sharp & Dohme LLC; Hospital Universitario Ramon y Cajal; Complejo Hospitalario... and other collaborators

Completed

Golimumab Trough Levels in Patients With Ulcerative Colitis (GLMLEVEL)

Ulcerative Colitis

Spain
CR-CSSS Champlain-Charles-Le Moyne

Completed

Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population (VancoDATABayes)

Adult | Vancomycin | Area Under Curve

Canada
Guy's and St Thomas' NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Study of the Golimumab Exposure-Response Relationship Using Serum Trough Levels (GO-LEVEL)

Ulcerative Colitis

United Kingdom
Novartis Pharmaceuticals

Terminated

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations (MACS1148)

CML | Philadelphia Chromosome Positive (Ph+) | Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels

United States
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Association of Cefepime Trough Levels With Clinical Efficacy and Neurotoxicity in Patients With Febrile Neutropenia

Pharmacokinetics | Pharmacodynamics | Cefepime

Belgium
Southern Medical University, China
Third Affiliated Hospital, Sun Yat-Sen University; 181 Central Hospital of...

Completed

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation.

Transplantation

China
Medical University of Vienna

Completed

The Vienna Prograf and Endothelial Progenitor Cell Extension Study (PEP-X)

Renal Failure | Immunosuppression
Macquarie University, Australia

Unknown

Effect of Enzalutamide Dose Reduction on Fatigue, Cognition, and Drug Trough Levels in Patients With Prostate Cancer (EFFECT)

Prostate Cancer

Australia
Universitaire Ziekenhuizen KU Leuven
Pfizer

Completed

An Observational Monocentric Study Investigating the Association Between Trough Serum Levels of Etanercept, Antibodies Towards Etanercept and Its Effectiveness in Psoriasis Patients (DERM)

Psoriasis
Asan Medical Center

Terminated

Voriconazole Trough Plasma Levels : Genetic Polymorphism, Efficacy, Safety in Patients With Hematologic Malignancy

Invasive Fungal Infection

Korea, Republic of
Hannover Medical School

Completed

Patient Education After Lung Transplantation Via Tablet Computers Versus Conventional Education

Lung Transplantation

Germany
Assiut University

Recruiting

Investigating Microparticle Levels In Filtered Packed Red Blood Cell Units

Packed Red Cells Causing Adverse Effects in Therapeutic Use

Egypt
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
Etlik Zubeyde Hanım Women's Health Care, Training...

Not yet recruiting

Effect of Antimullerian Hormone Levels on the Inflammatory Index, Phytochemical Index and NRF Nutrient Density (AMH)

Polycystic Ovary Syndrome | Diet Habit | AMH | Ovarian Failure
Bristol-Myers Squibb

Not yet recruiting

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Hepatic Impairment | Healthy Participants
Fundació Eurecat
University Rovira i Virgili

Not yet recruiting

Effect of a Grape Seed Proanthocyanidin Extract (GSPE) on LDL Cholesterol Levels in Rotating Night Shift Workers (CIRCAFENOL)

Cardiovascular Diseases | Cholesterol Level, High | Circadian Rhythm Sleep Disorder, Shift Work Type

Spain
Barcelona Institute for Global Health

Not yet recruiting

A Rapid Triage Test to Improve Risk-stratification of Febrile Children (EChiLiBRiST, Clinical Trial 1, Outpatients)

Infectious Disease | Child, Only | Febrile Illness
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
King's College Hospital NHS Trust

Recruiting

Different Levels of BiPAP

Bronchopulmonary Dysplasia

United Kingdom
Istanbul University - Cerrahpasa (IUC)

Not yet recruiting

The Effect of Therapeutic Play on Anxiety and Fear Levels in Children With Diabetes

Type1diabetes | Anxiety State | Therapeutic Play | Fear State
Celgene

Not yet recruiting

Study to Evaluate Safety, Drug Levels, Food and Relative Bioavailability of BMS-986365 in Healthy Adult Male Participants

Healthy Participants

United States
NMD Pharma A/S

Not yet recruiting

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis (SYNAPSE-MG)

Myasthenia Gravis | Myasthenia Gravis, MuSK
The First Affiliated Hospital of Xiamen University

Not yet recruiting

A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma

Gastric/Gastroesophageal Junction Adenocarcinoma
Brightseed

Not yet recruiting

To Evaluate the Impact of Consumption of a Bioactive Compound on Fasting Blood Glucose Levels in Asian Indians With Pre-diabetes

PreDiabetes
Uskudar University

Recruiting

The Effect of Exercise Practices on Hyperactivity Levels in Children With Autism Spectrum Disorder

Autism Spectrum Disorder | Autism

Turkey
Ottawa Fertility Centre
Quanovate Tech Inc.

Not yet recruiting

Correlation of Urinary and Serum Hormone Levels in Natural Cycle Frozen Embryo Transfer Cycles (MIRA)

Fertility Issues

Canada
Celgene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity

Healthy Participants

United States
Izmir Katip Celebi University

Recruiting

Evaluation of Salivary Galectin-8, Galectin-9 and RANKL Levels of Individuals With Different Periodontal Diseases

Periodontal Diseases

Turkey
University of Bologna

Not yet recruiting

Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels

Inflammation | Hypercholesterolemia

Italy
Izmir Katip Celebi University

Recruiting

Evaluation of Salivary Adseverin, 1-Alpha Defensin and sRANKL Levels of Individuals With Different Periodontal Diseases

Periodontal Diseases

Turkey
University Health Network, Toronto
Queen's University

Not yet recruiting

Albumin Utilization in Adult Cardiac Surgical Patients : A Multicentre Prospective Cohort Study (AlbACS-1Pro)

Antithrombin III Levels | Albumin Levels

Canada
Universiti Sains Malaysia

Not yet recruiting

Usage of Procalcitonin to Reduce Antibiotics Duration in VAP in Neurosurgical ICU

Antibiotic Side Effect
Hacettepe University

Recruiting

Investigation of Sarcopenia and Physical Fitness Levels of Geriatric Individuals Living in Nursing Homes and at Home

Geriatric Individuals

Turkey
Taipei Veterans General Hospital, Taiwan

Not yet recruiting

The Effectiveness of Combined Care for Knee Replacement Patients

Arthroplasty, Knee Replacement

Taiwan
Region Skane

Recruiting

Selective Head-and-neck Cooling on Biomarker Levels and Symptom Rating Following a Boxing Bout

Repetitive Head Impact | Selective Head and Neck Cooling

Sweden
Zoya Haitov Ben Zikri

Recruiting

Levels of Fear, Anxiety and Wound Healing Among Aental Surgery Patients Under Local Versus General Anesthesia

Wisdom Teeth Extraction or Jaw Implant

Israel
University Hospital, Basel, Switzerland

Not yet recruiting

Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics

Thiazide Associated Hyponatremia

Switzerland
I.R.C.C.S. Fondazione Santa Lucia

Not yet recruiting

Oral Supplementation Compared With Hyaluronic Acid Infiltration in Rotator Cuff Tendinopathies

Shoulder Pain | Dietary Supplements | Hyaluronic Acid | Tendinitis of Shoulder
Novo Nordisk A/S

Recruiting

A Research Study Looking Into Blood Levels of the Medicine NNC0519-0130 in the Body in Participants With Normal or Reduced Kidney Function

Diabetes Mellitus, Type 2

Germany
The Hospital of Vestfold
Sensocure AS

Not yet recruiting

Detecting Systemic Carbon Dioxide Levels With a Novel Biosensor (DISCO)

Pulmonary Disease, Chronic Obstructive | Neuromuscular Diseases | Hypercapnic Respiratory Failure | Obesity Hypoventilation Syndrome (OHS)

Norway
Institute of Liver and Biliary Sciences, India

Recruiting

Prevalence of CYP3A5 Polymorphisms in the Donors and ABCB1 Polymorphisms in the Recipients Undergoing Pediatric Liver Transplant and Their Influence on Tacrolimus Levels and Graft Function.

Pediatric Liver Transplant

India
Central Hospital, Nancy, France

Not yet recruiting

Interventional Reference Levels (IRL) in Digestive Endoscopy (EndoscopX)

Each Endoscopic Intervention Using X-rays

France
Celgene

Recruiting

A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants

Healthy Volunteers

United States
Xiao Wang

Recruiting

Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen

Estrogen | Postmenopausal Depression

China
Ege University
THE SCIENTIFIC AND TECHNOLOGICAL RESEARCH COUNCIL OF TÜRKİYE

Recruiting

Comparison of Salivary Procalcitonin (PCT) Levels and Serum PCT Levels

Bacterial Infections | Children, Only | Procalcitonin | Saliva

Turkey
Bristol-Myers Squibb

Recruiting

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Selverhan Yurttutan

Not yet recruiting

The Effect of Animated Movies and Storybooks on Fear and Anxiety Levels in Children With Type 1 Diabetes

Diabetes Mellitus, Type 1 | Anxiety | Fear | Child, Only | Nurse

Turkey

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