Search clinical trials for: tumor molecular targets

Total 117434 results

The Netherlands Cancer Institute

Not yet recruiting

Intradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma (MARIANE)

Melanoma

Netherlands
M.D. Anderson Cancer Center
KSQ Therapeutics, Inc.

Recruiting

A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

Melanoma | Head and Neck Neoplasms | Lung Neoplasms | Advanced Solid Tumor

United States
H. Lee Moffitt Cancer Center and Research Institute
Turnstone Biologics, Corp.

Recruiting

TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC

Squamous Cell Carcinoma of Head and Neck | Metastatic Squamous Cell Carcinoma

United States
Korea University Anam Hospital
Takeda; Korean Cancer Study Group

Not yet recruiting

Genome-Based Assessment of Niraparib (ZEJULA®) Efficacy in Advanced Solid TumorS With Homologous Recombination Deficiency

Efficacy
Sun Yat-sen University

Not yet recruiting

A Study of the Treatment of Disitamab Vedotin in Patients With Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer
Shenzhen University General Hospital

Not yet recruiting

Comparing Astragalus Plus Gemcitabine to Gemcitabine Alone as Neoadjuvant Treatment for Pancreatic Cancer Patients

Pancreatic Cancer

China
Xiao Chen

Recruiting

CXCR4 PET/MRI Targeted Imaging for Grading Diagnosis, Molecular Typing, and Prognostic Evaluation of Brain Glioma

Glioma

China
Hirschfeld Oncology

Not yet recruiting

Clinical Trial Evaluating Low Dose G-FLIP Plus Mitomycin C for Stage IV Pancreatic Cancer (GFLIPM)

Pancreatic Cancer

United States
Chang Gung Memorial Hospital

Recruiting

Evaluation of 68Ga-FAPI-46 and 18F-FDG PET/CT Imaging for Detecting Recurrent Tumor Lesions in Patients of Ovarian Cancer

Ovarian Cancer

Taiwan
Imperial College London

Not yet recruiting

A Study of Etoposide-carboplatin in Combination With Pembrolizumab and Lenvatinib Maintenance in HG-NETs (PELICAN)

Neuroendocrine Tumors
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin Lymphoma (OLYMPIA-4)

B-Cell Non-Hodgkin Lymphoma (B-NHL)

Taiwan, Spain, Korea, Republic of, Thailand, Italy, Malaysia, Turkey, Australia
N.N. Petrov National Medical Research Center of...

Recruiting

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations (NТО-RAS)

Melanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene Mutation

Russian Federation
Medical College of Wisconsin

Recruiting

Molecular Profile-related Individualized Targeted Therapy in Resected Pancreatic Cancer With High-Risk of Cancer Recurrence (PROTECT-PANC)

Pancreas Cancer

United States
Stephen Lownie
Dalhousie University

Recruiting

The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In Craniotomies

Bleeding | Brain Tumor

Canada
IRCCS San Raffaele

Recruiting

Integrated PET/MRI and Germline Variants to Differentiate Brain Tumopr Recurrence From Iatrogenicchanges in Children

Pediatric Brain Tumor

Italy
Peking University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Anlotinib, TQB2450 (PD-L1 Inhibitor), and Albumin-bound Paclitaxel Regimens in the Treatment of GC/GEJA

Gastric Cancer | Adenocarcinoma of Esophagogastric Junction

China
Ohio State University Comprehensive Cancer Center

Recruiting

EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers

Merkel Cell Carcinoma | Cutaneous Melanoma | Skin Squamous Cell Carcinoma

United States
Jonsson Comprehensive Cancer Center

Not yet recruiting

Fluoxetine for the Modification of Colorectal Tumor Immune Cells Before Surgery in Patients With Colorectal Cancer

Colorectal Adenocarcinoma

United States
RemeGen Co., Ltd.

Recruiting

DV Combined With Cadonilimab in Subjects With HER2-expressing Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on First-line Therapy

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

China
MedPacto, Inc.

Recruiting

Vactosertib and Imatinib Combination in Patients With Advanced Desmoid Tumor/Aggressive Fibromatosis (DT/AF) (MP-VAC-206)

Dermoid

Korea, Republic of
AstraZeneca

Recruiting

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Gastric Cancer | Pancreatic Adenocarcinoma | Gastroesophageal Junction Cancer

United States, Spain, United Kingdom, Korea, Republic of, Japan, Taiwan, Malaysia, Canada, Singapore, Moldova, Republic of, Australia, Georgia
Southern Medical University, China

Not yet recruiting

The Effectiveness of HP and TMZ Synergism on Adult Recurrence GBM

Glioblastoma Multiforme
Finn, Olivera, PhD
Breast Cancer Research Foundation; A Glimmer of Hope Foundation

Recruiting

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

Ductal Carcinoma in Situ

United States
Fudan University

Not yet recruiting

HR070803 in Combination With Oxaliplatin, 5-fluorouracil/LV Versus GX as Adjuvant Therapy for Pancreatic Cancer

Pancreatic Cancer

China
Li Xiao Wei

Not yet recruiting

HAIC Combine Tislelizumab and Lenvatinib in the Treatment of HCC With Type IV (Vp4) Portal Vein Tumor Thrombus (HAI-TL) (HAI-TL)

Hepatocellular Carcinoma With PVTT

China
Xijing Hospital
Beijing GD Initiative Cell Therapy Technology Co., Ltd.

Not yet recruiting

Allogeneic Gammadelta T Cells Combined With Interferon-α1b or PD-1 Monoclonal Antibody in Stage III-IV Amenable to Surgical Resection Melanoma

Melanoma
Changhai Hospital

Not yet recruiting

Perioperative Treatment in High-risk Resectable Pancreatic Cancer With NALIRIFOX

Pancreatic Cancer
Sarcoma Alliance for Research through Collaboration
Dana-Farber Cancer Institute; Cogent Biosciences, Inc.; The Life Raft Group

Not yet recruiting

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

Gastrointestinal Stromal Tumors | GIST

United States
Yizhuo Zhang

Recruiting

Ondansetron (ODF) Versus Ondansetron Intravenously for the Prevention of Chemotherapy-induced Nausea and Vomiting Compare in Children

Pediatric Solid Tumor, Unspecified, Protocol Specific

China
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors

Brain Metastases | Brain Metastases, Adult | High-grade Glioma

United States
Risen (Suzhou) Pharma Tech Co., Ltd.

Recruiting

A Clinical Study of JS105 in Combination With Other Anti-tumor Therapies in Patients With Solid Tumors

Advanced Solid Tumors

China
Australian & New Zealand Children's Haematology...
The Hospital for Sick Children; Kazia Therapeutics Limited; Day One Biopharmaceuticals... and other collaborators

Not yet recruiting

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Childhood Cancer | Refractory Cancer | Recurrent Cancer | Childhood Solid Tumor | Childhood Brain Tumor

Australia, Canada
National Institute of Cancerología
GlaxoSmithKline

Recruiting

Molecular Classification in Mexican Patients With Endometrial Cancer and Its Impact on Prognosis

Endometrial Cancer

Mexico
BioInvent International AB
Merck Sharp & Dohme LLC

Recruiting

BI-1910 as a Single Agent and in Combination With Pembrolizumab for the Treatment of Advanced Solid Tumors

Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Solid Tumors

Spain, Denmark, Poland, Sweden
Jinling Hospital, China

Not yet recruiting

To Compare the Clinical Application of 18F-LNC1007 Injection PET/CT and 18F-FDG PET/CT (18F-LNC1007)

Tumour
National Cancer Institute (NCI)

Not yet recruiting

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, The PARAMMUNE Trial

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions
Inge Marie Svane
Adaptimmune

Not yet recruiting

To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma (ADP-TILIL7)

Melanoma | Melanoma Stage IV | Melanoma Stage III
Daiichi Sankyo
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer (IDeate-Lung02)

Small Cell Lung Cancer

United States, Spain, Germany, Hungary, China, Italy, Korea, Republic of, United Kingdom, France, Belgium, Japan, Taiwan, Netherlands, Australia, Portugal, Poland, Turkey, Switzerland, Brazil, Canada, Romania
Chinese PLA General Hospital

Recruiting

Tumor Microenvironment in Gastric Cancer Patients Treated With Combined Immunotherapy and Chemotherapy

Gastric Cancer | Chemotherapy | Immunotherapy | Tumor Microenvironment

China
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Phase II Study of Concurrent Radiotherapy With Envafolimab and Capecitabine in LAPC

Pancreatic Cancer | Capecitabine | Radiotherapy | Envafolimab

China
Roswell Park Cancer Institute

Not yet recruiting

Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Tumors

Malignant Solid Neoplasm | Lung Neuroendocrine Neoplasm | Digestive System Neuroendocrine Neoplasm | Pancreatic Neuroendocrine Neoplasm

United States
M.D. Anderson Cancer Center
280Bio Inc

Recruiting

A Trial of YL-13027 in Combination With Gemcitabine and Nab-paclitaxel in Patients With Refractory Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer

United States
Samsung Medical Center

Not yet recruiting

Rivoceranib in Patients With Metastatic Thymic Epithelial Tumor

Thymic Epithelial Tumor

Korea, Republic of
University of Wisconsin, Madison

Recruiting

Correlating Early FDG PET/CT and ctDNA in Immune Checkpoint Inhibitor (ICI)-Treated Melanoma Patients

Melanoma | Unresectable Melanoma | Melanoma Stage IV | Melanoma Stage III

United States
Dong Bing Zhao

Recruiting

Gastric Cancer Organoids in the Screening of Neoadjuvant Drugs

Gastric Cancer | Neoadjuvant Therapy | Organoid

China
Fujian Cancer Hospital

Not yet recruiting

Phase II Study of the Combination of Irinotecan and POF (POFI) and Tislelizumab in Advanced Gastric Cancer

Gastric Cancer
Nanfang Hospital, Southern Medical University

Recruiting

Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients

Glioma, Malignant

China
Fudan University

Recruiting

Transcatheter Arterial Infusion to Patients With Advanced Pancreatic Cancer (PTCA199-9)

Pancreatic Cancer

China
Fudan University

Not yet recruiting

Oncolytic Virus Plus PD-1 Inhibitor to Patients With Advanced Pancreatic Cancer (PTCA199-8)

Pancreatic Cancer
The First Affiliated Hospital of Zhengzhou University

Recruiting

Duration of Adjuvant Chemotherapy for Gastric Cancer Patients at Pathological N3 Stage

Gastric Cancer

China

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