Search clinical trials for: unknown primary tumour

Total 17611 results

Avacta Life Sciences Ltd

Recruiting

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

Soft Tissue Sarcoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer | Biliary Tract Cancer | Oesophageal Cancer | Cancer of Unknown Primary Site

United States, United Kingdom
British Columbia Cancer Agency
Hoffmann-La Roche

Recruiting

Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity (CAPTIV-8)

Sarcoma | Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Lung Cancer | Skin Cancer | Gastrointestinal Cancer | Unknown Primary Tumors | Genitourinary Cancer

Canada
University of Warmia and Mazury
Stowarzyszenie Pacjentów i Osób Wspierających Chorych na Guzy Neuroendokrynne

Unknown

Peptide Receptor Radionuclide Therapy in the Treatment of Advanced, Non-resectable and/or Symptomatic Tumors With SSTR Overexpression (POLNETS_PRRT)

Neuroendocrine Tumors

Poland
Amgen

Completed

A Study of Carboplatin/Paclitaxel With Pegfilgrastim Supported by Haematopoietic Progenitor Cell Re-Infusion in Whole Blood

Breast Cancer | Ovarian Cancer | Lung Cancer
Prehospital Center, Region Zealand

Not yet recruiting

Primary or Secondary Drowning (DROWN_COD)

Drowning | Drowning; Anoxia | Drowning, Near | Drowning; Asphyxia | Drowning or Immersion of Unknown Intent | Drowning and Submersion, Undetermined Intent | Drowning and Submersion While in Bath-Tub | Drowning and Submersion While in Natural Water | Drowning and Submersion Due to Sailboat Sinking | Drowning... and other conditions

Denmark
Istituto Oncologico Veneto IRCCS

Recruiting

OLIGOS: Impact of Treatment on Primary Tumour in Patients With Newly Diagnosed Oligometastatic Neoplasia of the Prostate (OLIGOS)

Oligometastatic Prostate Carcinoma

Italy
Sun Yat-sen University
The First Affiliated Hospital of Anhui Medical University; Peking University... and other collaborators

Recruiting

PaCIFiC-CUP Classifies Cancer of Unknown Primary

Unknown Primary Tumors | DNA Methylation

China
CMR Surgical Ltd
Liverpool University Hospitals NHS Foundation Trust; Sintesi Research S.r.l.

Recruiting

Prospective Clinical Study to Assess the Safety and Efficacy of Versius, in Transoral Robotic Surgery

Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma, Unknown Primary

United Kingdom
University Medical Center Groningen

Recruiting

Real-time Targeted Fluorescence Endoscopy for Detection of the Primary Cancer Lesion in Patients With a Metastasis of Unknown Primary Tumor in the Head and Neck (REFLECT)

Oropharynx Cancer | Unknown Primary Tumors

Netherlands
Changi General Hospital
Khoo Teck Puat Hospital; Singapore General Hospital; Tan Tock Seng Hospital; Sengkang... and other collaborators

Recruiting

11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal Tumours

Primary Aldosteronism | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Adrenal Tumors

Singapore
Sohag University

Recruiting

Role of Positron Emission Tomography in Detecting Primary Tumor in Cases of Metastases of Unknown Origin

Metastasis of Unknown Origin

Egypt
Ourotech, Inc.
Imperial College Healthcare NHS Trust

Recruiting

Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO) (PEAR-GLIO)

Glioblastoma | Brain Tumor | Ependymoma | Oligodendroglioma | Glioma, Malignant

United Kingdom
Royal College of Surgeons, Ireland
Beaumont Hospital

Not yet recruiting

Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain Tumours

Brain Tumor | Hypopituitarism | Radiotherapy-Induced Hypopituitarism

Ireland
University of Thessaly

Recruiting

Venous Thromboembolism in Primary Pancreatic Tumour Resection (PaTR-VTE)

Pancreatic Cancer | Venous Thromboembolism | Pancreatic Ductal Adenocarcinoma

Greece
Regina Elena Cancer Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Weizmann Institute... and other collaborators

Recruiting

Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus

Liquid Biopsy | Squamous Cell Carcinoma of the Oropharynx | Lymph Node Metastasis | Carcinomas of Unknown Primary Site | High-risk Human Papillomavirus Infection | Occult Tumor of the Head and Neck Area

Italy
Tango Therapeutics, Inc.

Recruiting

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

Cervical Cancer | Breast Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Endometrial Cancer | Solid Tumors, Adult | Carcinoma of Unknown Primary

United States
Estas Tıbbi Mamülleri Medikal
Klinar CRO

Recruiting

Clinical Evaluation of Moment Tumor Hip Replacement Products (KRIOS)

Primary and Secondary Bone Tumor in the Proximal Femur Region

Turkey
Region Skane

Recruiting

On-treatment Biomarkers in Metastatic Colorectal Cancer for Life (On-CALL)

Metastatic Colorectal Cancer | Lung Metastases | Chemotherapy Effect | Peritoneal Metastases | Liver Metastasis Colon Cancer

Sweden
Rovere Querini Patrizia
ASST Fatebenefratelli Sacco; ASST Grande Ospedale Metropolitano Niguarda

Recruiting

Primary Care-Hospital Embedding: a Prospective, Multicentric, Observational Study (PRIME)

Heart Failure | Pneumonia | Hypertension | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Urinary Tract Infections | Deep Vein Thrombosis | Fever of Unknown Origin

Italy
University of Texas Southwestern Medical Center
National Cancer Institute (NCI)

Recruiting

A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Unknown Primary Cancer

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer

Head and Neck Cancer | Head and Neck Neoplasms | Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma

United States
Travera Inc
xCures

Recruiting

Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx) (TraveraRTGx)

Melanoma | Carcinoma, Renal Cell | Carcinoma | Carcinoma, Non-Small-Cell Lung | Carcinoma, Hepatocellular | Carcinoma, Pancreatic | Pancreatic Cancer | Mesothelioma | Cholangiocarcinoma | Carcinoma, Neuroendocrine | Carcinoma, Small Cell | Pleural Effusion, Malignant | Carcinoma, Pancreatic Ductal | Carcinoma of the... and other conditions

United States
Haukeland University Hospital

Recruiting

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

Primary Aldosteronism | Hypercortisolism | Aldosterone-Producing Adenoma

Norway
Emory University
National Cancer Institute (NCI); NovoCure Ltd.

Recruiting

Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-100M for the Treatment of Melanoma Brain Metastases

Metastatic Melanoma | Melanoma of Unknown Primary | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Mucosal Melanoma | Metastatic Ocular Melanoma

United States
State Scientific Centre of Coloproctology, Russian...

Recruiting

Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases

Digestive System Diseases | Gastrointestinal Diseases | Neoplasms | Neoplasms by Site | Gastrointestinal Neoplasms | Digestive System Neoplasms | Neoplasm Metastasis | Intestinal Diseases | Colorectal Neoplasms | Intestinal Neoplasms | Rectal Diseases | Neoplasms, Second Primary | Colonic Disease

Russian Federation
Peter MacCallum Cancer Centre, Australia

Recruiting

FAPI-CUP- Evaluating FAPI as a Novel Radiopharmaceutical for Cancer of Unknown Primary (FAPI-CUP)

Cancer of Unknown Primary Site

Australia
European Organisation for Research and Treatment...

Recruiting

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

Glioma | Ependymoma | Hemangiopericytoma | Diffuse Midline Glioma, H3 K27M-Mutant | Germ Cell Tumor | Embryonal Tumor | Hemangioblastoma | Glioneuronal Tumor | Choroid Plexus Tumor | Pineal Tumors | Tumor of the Sellar Region | Pineal Tumor | Melanocytic Tumor of CNS

Spain
Emory University
Astex Pharmaceuticals, Inc.

Recruiting

Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer

Head and Neck Carcinoma of Unknown Primary | Locally Advanced Head and Neck Squamous Cell Carcinoma | Locally Advanced Hypopharyngeal Squamous Cell Carcinoma | Locally Advanced Laryngeal Squamous Cell Carcinoma | Locally Advanced Nasopharyngeal Squamous Cell Carcinoma | Locally Advanced Oropharyngeal...

United States
Wei Xu

Recruiting

Tislelizumab Combined With Chemotherapy in the Treatment of Bone Metastases of Unknown Primary

Chemotherapy Effect | Gene Mutation-Related Cancer | Tislelizumab | Cancer of Unknown Primary | Bone Cancer Metastatic | Immune Evasion, Tumor

China
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditions

United States, Canada
Rapa Therapeutics LLC

Recruiting

RAPA-201 Therapy of Solid Tumors

Breast Cancer | Head and Neck Cancer | Gastric Cancer | Solid Tumor | Bladder Cancer | Triple Negative Breast Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Malignant Melanoma | Carcinoma of Unknown Primary | Squamous Cell Carcinoma of Larynx | Squamous Cell Carcinoma of Oral Cavity | Squamous Cell Carcinoma of Nasopharynx and other conditions

United States
Mayo Clinic

Recruiting

HEADLIGHT: Hypofractionated Proton Therapy for Head and Neck Cancers

Head and Neck Carcinoma | Metastatic Malignant Neoplasm in the Lymph Nodes | Nasal Cavity Carcinoma | Oral Cavity Carcinoma | Paranasal Sinus Carcinoma | Salivary Gland Carcinoma | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Hypopharyngeal Carcinoma | Laryngeal Carcinoma | Oropharyngeal Carcinoma and other conditions

United States
National University Hospital, Singapore

Recruiting

Role of Circulating Tumour DNA Testing in Assessing for Alterations of Primary Anti-EGFR Resistance in RAS/RAF Wild-type Metastatic Colorectal Cancer Patients

Colorectal Cancer

Singapore
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of Unknown Primary | Advanced Hypopharyngeal Squamous Cell Carcinoma | Advanced Laryngeal Squamous Cell Carcinoma | Advanced Oropharyngeal Squamous Cell Carcinoma

United States, Canada
Munich Leukemia Laboratory
Illumina, Inc.

Recruiting

Solving Riddles Through Sequencing (SIRIUS)

Leukemia | Rare Diseases | Refractory Lymphoma | Hematologic Malignancy | Refractory Leukemia | Unknown Primary Tumors

Germany
J.M. de Laat
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Precision Radiotherapy Using MR-linac for Pancreatic Neuroendocrine Tumours in MEN1 Patients (PRIME)

Multiple Endocrine Neoplasia Type 1 | Neuroendocrine Tumor of Pancreas

Netherlands
Travera Inc
John B. Amos Cancer Center

Not yet recruiting

Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to Drugs

Carcinoma, Renal Cell | Carcinoma | Carcinoma, Non-Small-Cell Lung | Carcinoma, Hepatocellular | Carcinoma, Pancreatic | Mesothelioma | AML | Cholangiocarcinoma | Stage IV Lung Cancer | Carcinoma, Neuroendocrine | Stage IV Breast Cancer | Carcinoma, Ductal | Malignant Ascites | Carcinoma Prostate | Stage III Breast Cancer and other conditions

United States
Fudan University

Recruiting

Real World Study of Diagnosis and First-line Treatment Among Patients With Cancer of Unknown Primary in China

Cancer of Unknown Primary Site

China
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
Fudan University

Recruiting

PD-1 Inhibitor and Nab-paclitaxel and Bevacizumab in CUP

Cancer of Unknown Primary

China
SOLTI Breast Cancer Research Group
Novartis

Recruiting

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors (ACROPOLI)

Melanoma | Sarcoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Uterine Carcinosarcoma | Mesothelioma | Cholangiocarcinoma | Lung Adenocarcinoma | Triple Negative Breast Cancer | Epithelial Ovarian Cancer | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal... and other conditions

Spain
University Hospital Ostrava

Recruiting

Consolidation Conventional Radiotherapy + Stereotactic Body Radiotherapy at 3 Months After First-line Chemotherapy in Stage IV Oligometastatic Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Czechia
Ohio State University Comprehensive Cancer Center

Recruiting

Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer

Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Pharyngeal Squamous Cell Carcinoma | Locally Recurrent Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma of Unknown Primary | Resectable Head and Neck Squamous Cell Carcinoma

United States
Fondazione Sandro Pitigliani
Clinical Research Technology S.r.l.

Recruiting

To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer (TIRESIAS)

Metastatic Breast Cancer | HER2-negative Breast Cancer | ER Positive Breast Cancer

Italy
Umeå University

Recruiting

Different Fractionation Schedules of Radiotherapy to the Primary Tumour in Metastatic Hormone Sensitive Prostate Cancer (Hypo-M1)

Prostate Cancer | Metastatic Cancer | Radiotherapy Side Effect

Sweden
Peking University
Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China

Recruiting

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (VISIONARY)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Esophageal Squamous Cell Carcinoma | Biliary Tract Neoplasms | Unknown Primary Cancer | Digestive Cancer

China
Memorial Sloan Kettering Cancer Center

Recruiting

Lutathera in People With Gastroenteropancreatic (GEP), Bronchial or Unknown Primary Neuroendocrine Tumors That Have Spread to the Liver

Neuroendocrine Tumors | Liver-Dominant Metastatic Pancreatic Neuroendocrine Tumors

United States
TargetCancer Foundation
Foundation Medicine

Recruiting

TCF-001 TRACK (Target Rare Cancer Knowledge) Study (TRACK)

Cholangiocarcinoma | Cancer of Unknown Primary Site | Rare Cancers

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Cancer Genetic Testing in Ethnic Populations

Malignant Solid Neoplasm | Breast Carcinoma | Digestive System Carcinoma | Head and Neck Carcinoma | Skin Carcinoma | Malignant Female Reproductive System Neoplasm | Malignant Brain Neoplasm | Carcinoma of Unknown Primary | Central Nervous System Carcinoma | Genitourinary System Carcinoma | Malignant Musculoskeletal...

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Melanoma of Unknown Primary | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC... and other conditions

United States

Search clinical trials for: unknown primary tumour

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