Search clinical trials for: zirconium

Total 78 results

Leiden University Medical Center
AstraZeneca

Not yet recruiting

Sodium Zirconium Cyclosilicate to Allow Liberal Fruit and Vegetable Intake for Patients With CKD Stage 3b and 4 (LIBRAL)

Diet Modification | Chronic Kidney Disease | Hyperkalemia | Sodium Zirconium Cyclosilicate
Peking University First Hospital

Recruiting

The Effect of Potassium Lowering Drugs on Cardiac Electrical Stability in Hemodialysis Patients (ART Study)

Cardiac Arrhythmia | Potassium Imbalance | Dialysis; Complications

China
Aplagon Oy
TRACER Europe BV

Recruiting

Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography) (CHASE)

Peripheral Arterial Occlusive Disease | Critical Limb Ischemia

Netherlands
AstraZeneca

Recruiting

A National, Multicenter, Prospective, Observational Study to Assess Patient Characteristics, Treatment Algorithms and Disease Management of Hyperkalaemia Patients With Chronic Kidney Disease or Under Dialysis or With Heart Failure, Treated With Sodium Zirconium Cyclosilicate in Greece (SHIELD)

Hyperkalaemia

Greece
Alexandria University

Recruiting

SZC Versus SPS for Treatment of Hyperkalemia in Hemodialysis Patients

Hyperkalemia

Egypt
Université de Sherbrooke
Eli Lilly and Company; Chorus Wellness Inc.; AL-S Pharma AG

Recruiting

Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Canada
Robert Flavell, MD, PhD
National Cancer Institute (NCI)

Recruiting

Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma

Multiple Myeloma | Plasma Cell Myeloma

United States
Michael Topf

Recruiting

(89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck

United States
ImaginAb, Inc.
University of Hull

Recruiting

CD8 Minibody Repeatability Study (PRETZCEL)

Melanoma | Renal Cell Carcinoma

United Kingdom
Leiden University Medical Center

Recruiting

89Zr-Bevacizumab PET/CT Imaging in NF2 Patients

Neurofibromatosis 2

Netherlands
Cairo University

Recruiting

Evaluation of Using Patient Specific Zirconium Dioxide Implant Versus Patient Specific Titanium Implant in Treatment of Chronic Condylar Dislocation

Recurrent Dislocation of Temporomandibular Joint (Disorder)

Egypt
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)

Lymphoma | Metastatic Malignant Solid Neoplasm

United States
Medical University of Graz

Recruiting

Clinical Outcome of Two-piece Zirconia Implants in Immediate Implant Placement

Immediate Implantation of Two-piece Zirconia Dental Implants

Austria
AstraZeneca

Recruiting

Continuing Sodium Zirconium Cyclosilicate (SZC) After Discharge Study (CONTINUITY)

Chronic Kidney Disease | Hyperkalaemia

United Kingdom, Spain, Belgium, Italy, Netherlands, France, Germany
Branemarkkliniken

Recruiting

RCT: Titanium vs FCZ vs Zirconia Framework

Dental Prosthesis Failure

Sweden
ImaginAb, Inc.

Recruiting

Study of Zirconium Zr 89 Crefmirlimab Berdoxam PET/CT in Subjects With Advanced or Metastatic Malignancies (iPREDICT)

Melanoma | Renal Cell Carcinoma | Non Small Cell Lung Cancer | Merkel Cell Carcinoma, Unspecified

United States, Australia, Belgium, Netherlands, Switzerland, United Kingdom
St George's, University of London

Recruiting

Lokelma for RAAS Maximisation in CKD & Heart Failure. (LIFT)

Chronic Kidney Diseases | Heart Failure With Reduced Ejection Fraction | Hyperkalemia | ACE Inhibitor Induced Hyperkalaemia | Mineralocorticoid Resistant Hyperkalemia

United Kingdom
Cairo University

Not yet recruiting

Wear of Enamel Antagonist to ZLS Crowns (zls)

Wear, Tooth | Wear, Occlusal
Michael Fu
Göteborg University; AstraZeneca

Recruiting

OPtimizing Aldosterone Receptor Antagonist Therapy by Sodium Zirconium Cyclosilicate in Heart Failure (OPRA-HF)

Heart Failure | Hyperkalemia

Sweden
CeraRoot SL

Recruiting

PMCF Study of CeraRoot Ceramic Implants One-piece: 1year, 5 Years Follow up

Tooth Loss | Ceramic Implant

Spain
University of California, Irvine

Recruiting

Comparison of Potassium Binders in the ER (KBindER)

Acute Hyperkalemia | Oral Potassium Binders

United States
University of Bern

Recruiting

Titanium Zirconium (TiZr) Mini Implants

Dental Implants

Switzerland
AstraZeneca

Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia (PEDZ-K)

Hyperkalaemia

China, Germany, United States, Ukraine, Spain, Japan, United Kingdom, Canada, Poland, Romania, Russian Federation, Brazil
University of Alabama at Birmingham

Recruiting

Positron Emission Tomography (PET) Imaging With Zirconium-89 (89Zr)-Trastuzumab for Prediction of HER2 Targeted Therapy Effectiveness

Breast Cancer

United States
Amsterdam UMC, location VUmc
Bristol-Myers Squibb

Recruiting

Uptake and Biodistribution of 89Zirconium-labeled Ipilimumab in Ipilimumab Treated Patients With Metastatic Melanoma (Zirconipi)

Melanoma

Netherlands
AstraZeneca

Active, not recruiting

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone (REALIZE-K)

Heart Failure With Reduced Ejection Fraction | Hyperkalaemia

United States, Spain, Canada, Brazil, Hungary, Czechia, Ukraine, Poland, United Kingdom
AstraZeneca

Terminated

Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

Hyperkalemia

United States, Italy, Spain, Taiwan, Thailand, Vietnam, Russian Federation, Canada, Hungary, Mexico, China, Austria, Turkey, Brazil, Germany, Poland, Czechia, United Kingdom, Bulgaria, Slovakia, Peru, Ukraine, Japan, Argentina, Malaysia, ...
Malmö University

Completed

Zirconium Dioxide Fixed Dental Prosthesis.

Missing Teeth

Sweden
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects

Hyperkalaemia

Germany
AstraZeneca

Terminated

A Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Chronic Kidney Disease (CKD) Progression in Participants With CKD and Hyperkalaemia or at Risk of Hyperkalaemia (STABILIZE-CKD)

Renal Insufficiency, Chronic | Hyperkalemia

United States, Italy, Spain, Thailand, Vietnam, Turkey, Canada, Philippines, China, Malaysia, Taiwan, Brazil, Japan, Bulgaria, Russian Federation, Poland, Argentina, Mexico, Ukraine, India, Puerto Rico
Crescendo Biologics Ltd.
University Medical Center Groningen

Active, not recruiting

A Phase I Study to Assess PSMA+ and PSMA- Tumour Lesions

Advanced and/or Metastatic Solid Tumours

Netherlands
Institut Straumann AG

Completed

Performance Evaluation of FullCeram Implants in Single Tooth Gaps

Tooth Loss

Germany
Mansoura University

Completed

Effect of Adding Zirconium Oxide Nanoparticles to Printable Implant Overdenture

Prosthesis Durability

Egypt
Mansoura University

Completed

Patient Satisfaction , Prosthetic Complications and Clinical Outcomes of PEEK Composite Versus Titanium Zirconium

Patient Satisfaction | Clinical Outcomes | Prosthetic Complication

Egypt
AstraZeneca

Active, not recruiting

A Multicenter, Prospective, Non-interventional Cohort Study to Evaluate the Safety and Treatment Pattern of Sodium Zirconium Cyclosilicate for Hyperkalaemia Management in Real World Practice in China (ACTUALIZE)

Hyperkalaemia

China
AstraZeneca

Terminated

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease (NEUTRALIZE)

Chronic Kidney Disease | Metabolic Acidosis | Hyperkalaemia

United States, Puerto Rico
Barts & The London NHS Trust

Terminated

The ORTIZ Study: Optimising RASi Therapy With SZC (ORTIZ)

Diabetes Mellitus, Type 2 | CKD | Hyperkalemia

United Kingdom
Abramson Cancer Center at Penn Medicine
ImaginAb, Inc.

Enrolling by invitation

Zr89 + PET Companion Trial

Melanoma (Skin)

United States
Jules Bordet Institute
Roche Pharma AG

Active, not recruiting

HER2 Imaging Study to Identify HER2 Positive Metastatic Breast Cancer Patient Unlikely to Benefit From T-DM1 (ZEPHIR)

HER-2 Positive Breast Cancer

Belgium, Netherlands
AstraZeneca
ImaginAb, Inc.

Terminated

A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours

Carcinoma, Non-Small-Cell Lung | Urinary Bladder Neoplasms | Colorectal Cancer

United States, Canada
Karolinska Institutet
AstraZeneca

Completed

Healthy Diet Rich in Potassium to Chronic Kidney Disease With Sodium Zirconium Cyclosilicate: A Feasibility Study (HELPFUL)

Chronic Kidney Disease Stage 5 | Hyperkalemia | Chronic Kidney Disease stage4

Sweden
Andrei Iagaru
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Panitumumab-IRDye800 and 89Zr-Panitumumab in Identifying Metastatic Lymph Nodes in Patients With Squamous Cell Head and Neck Cancer

Squamous Cell Carcinoma of the Head and Neck | Carcinoma of the Head and Neck

United States
AstraZeneca

Completed

Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects (DIALIZE China)

Hyperkalemia

China
AstraZeneca

Terminated

Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia (GRAZE)

Hyperkalaemia

United States
AstraZeneca

Completed

A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia. (HARMONIZE Asia)

Hyperkalemia

China
Guangdong Provincial People's Hospital

Completed

Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy (SZC)

Hyperparathyroidism, Secondary | Hyperkalemia | Sodium Zirconium Cyclosilicate
Minia University

Completed

Quality of Life for Children With Zirconium Anteroir Crowns Versus Strip Composite Crowns

Caries

Egypt
AstraZeneca

Terminated

Potassium Reduction Initiative to Optimize RAAS Inhibition Therapy With Sodium Zirconium Cyclosilicate in Heart Failure (PRIORITIZE HF)

Heart Failure

United States, Canada, Brazil, Slovakia, Hungary, Romania, Poland, Russian Federation, Bulgaria
Ahmad Elheeny

Completed

Primary Molars Restoration Using CAD/CAM Crowns.

Restoration of Primary Molars With CAD/CAM Crowns

Egypt
Brigham and Women's Hospital

Unknown

Potassium Binder in CKD Patients (With Hyperkalemia) (DiPo Trial)

Chronic Kidney Diseases | Hyperkalemia

United States

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