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Electromyographic Response to Blood Flow Restriction Exercise in Healthy Adults

16. juni 2026 opdateret af: Carlos Fernández-Morales, Universidad de Extremadura

Electromyographic Analysis of Immediate Neuromuscular Response After Low-Load Knee Extension Exercise With and Without Blood Flow Restriction in Healthy Adults

This study evaluated the immediate neuromuscular response to low-load knee extension exercise performed with and without blood flow restriction in healthy young adults.

Blood flow restriction is a training method in which a pressure cuff is applied to the upper part of a limb to partially reduce blood flow during exercise. In this study, each participant completed the same knee extension exercise protocol under two conditions: with blood flow restriction and without blood flow restriction. The blood flow restriction pressure was individualized according to each participant's arterial occlusion pressure.

Surface electromyography was used to record the activity of the vastus lateralis muscle during the exercise protocol. Muscle activation was mainly assessed using the root mean square amplitude normalized to a maximal voluntary isometric contraction measured before exercise. Maximal voluntary isometric contraction was also recorded before and after the protocol to explore immediate changes in maximal muscle activation.

The study was conducted in healthy adults and aimed to compare the electromyographic response between the blood flow restriction and non-restriction conditions during a standardized low-load exercise task.

Studieoversigt

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

24

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

    • Badajoz
      • Badajoz, Badajoz, Spanien, 06006
        • University of Extremadura

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen
  • Ældre voksen

Tager imod sunde frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Age between 18 and 65 years.
  • Healthy adults.
  • Absence of active pain or musculoskeletal injury in the lower limbs at the time of assessment.
  • Ability to understand the study procedures.
  • Voluntary agreement to participate and provision of written informed consent.

Exclusion Criteria:

  • History of neuromuscular disease.
  • History of cardiovascular disease.
  • History of peripheral vascular disease.
  • History of thromboembolic events.
  • Uncontrolled hypertension.
  • Skin lesions or skin conditions preventing placement of the blood flow restriction cuff or surface electromyography electrodes.
  • Recent lower limb surgery.
  • Pregnancy.
  • Any other contraindication to blood flow restriction exercise.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Grundvidenskab
  • Tildeling: Randomiseret
  • Interventionel model: Crossover opgave
  • Maskning: Enkelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Low-load knee extension exercise with blood flow restriction
Participants performed a low-load knee extension exercise protocol with blood flow restriction applied to the proximal thigh. The blood flow restriction pressure was individualized and set at 80% of the participant's arterial occlusion pressure. Surface electromyography of the vastus lateralis was recorded throughout the exercise protocol.
Participants completed a low-load knee extension exercise protocol consisting of 75 repetitions distributed across four sets: 30, 15, 15, and 15 repetitions. Surface electromyography of the vastus lateralis was recorded continuously during the protocol.
Aktiv komparator: Low-load knee extension exercise without blood flow restriction
Participants performed the same low-load knee extension exercise protocol without blood flow restriction. Surface electromyography of the vastus lateralis was recorded throughout the exercise protocol.
Participants completed a low-load knee extension exercise protocol consisting of 75 repetitions distributed across four sets: 30, 15, 15, and 15 repetitions. Surface electromyography of the vastus lateralis was recorded continuously during the protocol.
A pneumatic cuff was placed on the proximal thigh and inflated to 80% of the participant's individualized arterial occlusion pressure during the low-load knee extension exercise protocol.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Vastus Lateralis Electromyographic Amplitude Normalized to Maximal Voluntary Isometric Contraction
Tidsramme: During the exercise protocol, within a single experimental session.
Surface electromyographic activity of the vastus lateralis was assessed during the low-load knee extension exercise protocol. The root mean square amplitude was normalized to the maximal voluntary isometric contraction recorded before exercise and expressed as percentage of maximal voluntary isometric contraction (%MVIC). Measurements were extracted at predefined time points across the four exercise sets in both experimental conditions.
During the exercise protocol, within a single experimental session.

Samarbejdspartnere og efterforskere

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Datoer for undersøgelser

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Studer store datoer

Studiestart (Faktiske)

1. februar 2026

Primær færdiggørelse (Faktiske)

15. april 2026

Studieafslutning (Faktiske)

15. april 2026

Datoer for studieregistrering

Først indsendt

12. juni 2026

Først indsendt, der opfyldte QC-kriterier

12. juni 2026

Først opslået (Faktiske)

17. juni 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

18. juni 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

16. juni 2026

Sidst verificeret

1. juni 2026

Mere information

Begreber relateret til denne undersøgelse

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