Ice Application for Oxacillin-Related Phlebitis and Pain
10. september 2026 opdateret af: Kuan-Yu Lin, Central Taiwan University of Science and Technology
Effect of Ice Application on Reducing Peripheral Vascular Phlebitis and Pain After Oxacillin Injection: A Randomized Single-Blind Controlled Trial
This randomized controlled trial evaluated whether ice application could reduce pain and peripheral intravenous phlebitis associated with oxacillin administration.
Hospitalized patients receiving intravenous oxacillin were assigned to either an ice application group or a control group.
In the intervention group, ice was applied to the area around the peripheral intravenous catheter before oxacillin administration.
In the control group, a room-temperature water bag was applied in the same manner.
Pain after oxacillin administration and signs of phlebitis at the intravenous catheter site were assessed and compared between the two groups.
The study aimed to determine whether ice application could provide a simple, non-pharmacological approach to reducing oxacillin-related pain and phlebitis.
Studieoversigt
Status
Afsluttet
Intervention / Behandling
Undersøgelsestype
Interventionel
Tilmelding (Faktiske)
86
Fase
- Ikke anvendelig
Kontakter og lokationer
Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.
Studiesteder
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Fengyuan, Taiwan
- Feng Yuan Hospital, Ministry of Health and Welfare
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Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
- Voksen
Tager imod sunde frivillige
Ingen
Beskrivelse
Inclusion Criteria:
Adults aged 20 to 60 years. Conscious and able to participate in the study. Intravenous injection site located on either hand. Receiving a single antibiotic medication during the study. Eligible regardless of sex or medical diagnosis.
Exclusion Criteria:
Dementia. Psychiatric disorders. Skin rash at the study site. Purpura. Pregnancy. Current oral corticosteroid use. Hemodialysis. Administration of a second medication or an injection containing two or more medications during the study.
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Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Forebyggelse
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Enkelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
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Eksperimentel: Ice Application Group
Participants assigned to this group received ice application around the peripheral intravenous catheter site before intravenous oxacillin administration.
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Ice was applied around the peripheral intravenous catheter site before intravenous oxacillin administration.
The intervention was intended to reduce pain associated with oxacillin administration and the occurrence of peripheral intravenous phlebitis.
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Aktiv komparator: Room-Temperature Water-Bag Control Group
Participants assigned to this group received a room-temperature water-bag application around the peripheral intravenous catheter site before intravenous oxacillin administration.
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A room-temperature water bag was applied around the peripheral intravenous catheter site before intravenous oxacillin administration as the control condition.
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
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Pain Intensity After Intravenous Oxacillin Administration
Tidsramme: Up to 72 hours after intravenous oxacillin administration
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Pain intensity associated with intravenous oxacillin administration was assessed repeatedly after oxacillin administration across nine 8-hour intervals during the 72-hour observation period.
Higher pain scores indicated greater pain intensity.
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Up to 72 hours after intravenous oxacillin administration
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Pain Intensity After Intravenous Oxacillin Administration
Tidsramme: From 1 to 72 hours after initiation of the study intervention, assessed at 1-8, 9-16, 17-24, 25-32, 33-40, 41-48, 49-56, 57-64, and 65-72 hours.
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Pain intensity associated with intravenous oxacillin administration was assessed using a numerical rating scale, with higher scores indicating greater pain.
Pain was assessed repeatedly after oxacillin administration across nine 8-hour intervals during the 72-hour observation period.
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From 1 to 72 hours after initiation of the study intervention, assessed at 1-8, 9-16, 17-24, 25-32, 33-40, 41-48, 49-56, 57-64, and 65-72 hours.
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Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Faktiske)
7. april 2022
Primær færdiggørelse (Faktiske)
31. december 2022
Studieafslutning (Faktiske)
31. december 2022
Datoer for studieregistrering
Først indsendt
10. september 2026
Først indsendt, der opfyldte QC-kriterier
10. september 2026
Først opslået (Faktiske)
15. september 2026
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
15. september 2026
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
10. september 2026
Sidst verificeret
1. september 2026
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- FYH-IRB-111004
- 111004 (Anden identifikator: Feng Yuan Hospital, Ministry of Health and Welfare)
Plan for individuelle deltagerdata (IPD)
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INGEN
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