Ice Application for Oxacillin-Related Phlebitis and Pain
10. september 2026 oppdatert av: Kuan-Yu Lin, Central Taiwan University of Science and Technology
Effect of Ice Application on Reducing Peripheral Vascular Phlebitis and Pain After Oxacillin Injection: A Randomized Single-Blind Controlled Trial
This randomized controlled trial evaluated whether ice application could reduce pain and peripheral intravenous phlebitis associated with oxacillin administration.
Hospitalized patients receiving intravenous oxacillin were assigned to either an ice application group or a control group.
In the intervention group, ice was applied to the area around the peripheral intravenous catheter before oxacillin administration.
In the control group, a room-temperature water bag was applied in the same manner.
Pain after oxacillin administration and signs of phlebitis at the intravenous catheter site were assessed and compared between the two groups.
The study aimed to determine whether ice application could provide a simple, non-pharmacological approach to reducing oxacillin-related pain and phlebitis.
Studieoversikt
Status
Fullført
Intervensjon / Behandling
Studietype
Intervensjonell
Registrering (Faktiske)
86
Fase
- Ikke aktuelt
Kontakter og plasseringer
Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.
Studiesteder
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Fengyuan, Taiwan
- Feng Yuan Hospital, Ministry of Health and Welfare
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Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
Tar imot friske frivillige
Nei
Beskrivelse
Inclusion Criteria:
Adults aged 20 to 60 years. Conscious and able to participate in the study. Intravenous injection site located on either hand. Receiving a single antibiotic medication during the study. Eligible regardless of sex or medical diagnosis.
Exclusion Criteria:
Dementia. Psychiatric disorders. Skin rash at the study site. Purpura. Pregnancy. Current oral corticosteroid use. Hemodialysis. Administration of a second medication or an injection containing two or more medications during the study.
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Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Forebygging
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Enkelt
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
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Eksperimentell: Ice Application Group
Participants assigned to this group received ice application around the peripheral intravenous catheter site before intravenous oxacillin administration.
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Ice was applied around the peripheral intravenous catheter site before intravenous oxacillin administration.
The intervention was intended to reduce pain associated with oxacillin administration and the occurrence of peripheral intravenous phlebitis.
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Aktiv komparator: Room-Temperature Water-Bag Control Group
Participants assigned to this group received a room-temperature water-bag application around the peripheral intravenous catheter site before intravenous oxacillin administration.
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A room-temperature water bag was applied around the peripheral intravenous catheter site before intravenous oxacillin administration as the control condition.
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Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
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Pain Intensity After Intravenous Oxacillin Administration
Tidsramme: Up to 72 hours after intravenous oxacillin administration
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Pain intensity associated with intravenous oxacillin administration was assessed repeatedly after oxacillin administration across nine 8-hour intervals during the 72-hour observation period.
Higher pain scores indicated greater pain intensity.
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Up to 72 hours after intravenous oxacillin administration
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Pain Intensity After Intravenous Oxacillin Administration
Tidsramme: From 1 to 72 hours after initiation of the study intervention, assessed at 1-8, 9-16, 17-24, 25-32, 33-40, 41-48, 49-56, 57-64, and 65-72 hours.
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Pain intensity associated with intravenous oxacillin administration was assessed using a numerical rating scale, with higher scores indicating greater pain.
Pain was assessed repeatedly after oxacillin administration across nine 8-hour intervals during the 72-hour observation period.
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From 1 to 72 hours after initiation of the study intervention, assessed at 1-8, 9-16, 17-24, 25-32, 33-40, 41-48, 49-56, 57-64, and 65-72 hours.
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Samarbeidspartnere og etterforskere
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Studierekorddatoer
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Studer hoveddatoer
Studiestart (Faktiske)
7. april 2022
Primær fullføring (Faktiske)
31. desember 2022
Studiet fullført (Faktiske)
31. desember 2022
Datoer for studieregistrering
Først innsendt
10. september 2026
Først innsendt som oppfylte QC-kriteriene
10. september 2026
Først lagt ut (Faktiske)
15. september 2026
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
15. september 2026
Siste oppdatering sendt inn som oppfylte QC-kriteriene
10. september 2026
Sist bekreftet
1. september 2026
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- FYH-IRB-111004
- 111004 (Annen identifikator: Feng Yuan Hospital, Ministry of Health and Welfare)
Plan for individuelle deltakerdata (IPD)
Planlegger du å dele individuelle deltakerdata (IPD)?
NEI
Legemiddel- og utstyrsinformasjon, studiedokumenter
Studerer et amerikansk FDA-regulert medikamentprodukt
Nei
Studerer et amerikansk FDA-regulert enhetsprodukt
Nei
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