Understanding GPs' clinical reasoning processes involved in managing patients suffering from multimorbidity: A systematic review of qualitative and quantitative research

Sarah Cairo Notari, Julia Sader, Nathalie Caire Fon, Johanna Maria Sommer, Anne Catherine Pereira Miozzari, Danilo Janjic, Mathieu Nendaz, Marie-Claude Audétat, Sarah Cairo Notari, Julia Sader, Nathalie Caire Fon, Johanna Maria Sommer, Anne Catherine Pereira Miozzari, Danilo Janjic, Mathieu Nendaz, Marie-Claude Audétat

Abstract

Background: Most consultations in primary care involve patients suffering from multimorbidity. Nevertheless, few studies exist on the clinical reasoning processes of general practitioners (GPs) during the follow-up of these patients. The aim of this systematic review is to summarise published evidence on how GPs reason and make decisions when managing patients with multimorbidity in the long term.

Methods: A search of the relevant literature from Medline, Embase, PsycINFO, and ERIC databases was conducted in June 2019. The search terms were selected from five domains: primary care, clinical reasoning, chronic disease, multimorbidity, and issues of multimorbidity. Qualitative, quantitative, and mixed-methods studies published in English and French were included. Quality assessment was performed using the Mixed Methods Appraisal Tool.

Results: A total of 2 165 abstracts and 362 full-text articles were assessed. Thirty-two studies met the inclusion criteria. Results showcased that GPs' clinical reasoning during the long-term management of multimorbidity is about setting intermediate goals of care in an ongoing process that adapts to the patients' constant evolution and contributes to preserve their quality of life. In the absence of guidelines adapted to multimorbidity, there is no single correct plan, but competing priorities and unavoidable uncertainties. Thus, GPs have to consider and weigh multiple factors simultaneously. In the context of multimorbidity, GPs describe their reasoning as essentially intuitive and seem to perceive it as less accurate. These clinical reasoning processes are nevertheless more analytical as they might think and rooted in deep knowledge of the individual patient.

Conclusions: Although the challenges GPs are facing in the long-term follow-up of patients suffering from multimorbidity are increasingly known, the literature currently offers limited information about GPs' clinical reasoning processes at play. GPs tend to underestimate the complexity and richness of their clinical reasoning, which may negatively impact their practice and their teaching.

Conflict of interest statement

The authors declare no conflict of interest.

© 2021 The Authors. International Journal of Clinical Practice published by John Wiley & Sons Ltd.

Figures

FIGURE 1
FIGURE 1
Flow diagram of study selection. Abbreviations: GP, General Practitioner. aEndNote software (Clarivate Analytics) was used to remove duplicates. bArticles considered as “off topic” because of the lack of data on GPs’ clinical approach, management or follow‐up of multimorbidity. No relevant (implicit or explicit) information on clinical reasoning could be extracted. cArticles on acute diseases, accidents, emergency care or preventive care. dArticles presenting data from other healthcare professionals (eg, nurses, pharmacists, physiotherapists) or from patients. Articles presenting data extracted from medical records were included if results allowed to illustrate the GPs’ clinical reasoning processes. Articles presenting data from the mixed sample including GPs were excluded, unless specific data from GPs were presented. eArticles reporting unextractable or limited and ungeneralisable data, meaning that these papers presented results that dealt with the practical management of specific diseases and/or treatment and do not allow us access to the underlying clinical reasoning processes. fArticles exclusively focused on clinical reasoning in the diagnosis phase

References

    1. Multimorbidity: Technical Series on Safer Primary Care. Geneva: World Health Organization; 2016. Licence: CC BY‐NC‐SA 3.0 IGO.
    1. Starfield B, Lemke KW, Bernhardt T, Foldes SS, Forrest CB, Weiner JP. Comorbidity: implications for the importance of primary care in ‘case’ management. Ann Fam Med. 2003;1:8‐14. 10.1370/afm.1
    1. Starfield B. New paradigms for quality in primary care. Br J Gen Pract. 2001;51:303‐309.
    1. Montague T, Gogovor A, Aylen J, et al. Patient‐centred care in Canada: key components and the path forward. Healthc Q. 2017;20:50‐56. 10.12927/hcq.2017.25136
    1. Excoffier S, Herzig L, N’Goran AA, Deruaz‐Luyet A, Haller DM. Prevalence of multimorbidity in general practice: a cross‐sectional study within the Swiss Sentinel Surveillance System (Sentinella). BMJ Open. 2018;8:e019616. 10.1136/bmjopen-2017-019616
    1. Darer JD, Hwang W, Pham HH, Bass EB, Anderson M. More training needed in chronic care: a survey of U.S. Physicians. Acad Med. 2004;79:541‐548.
    1. Audétat M‐C, Laurin S, Sanche G, et al. Clinical reasoning difficulties: a taxonomy for clinical teachers. Med Teach. 2013;35:e984‐e989. 10.3109/0142159X.2012.733041
    1. Durning SJ, Artino AR Jr, Schuwirth L, van der Vleuten C. Clarifying assumptions to enhance our understanding and assessment of clinical reasoning. Acad Med. 2013;88:442‐448. 10.1097/ACM.0b013e3182851b5b
    1. Cook DA, Durning SJ, Sherbino J, Gruppen LD. Management reasoning: implications for health professions educators and a research agenda. Acad Med. 2019;94:1310‐1316. 10.1097/ACM.0000000000002768
    1. Higgs J, Jones MA. Clinical decision making and multiple problem spaces. In: Higgs J, Jones M, Loftus S, Christensen N, eds. Clinical reasoning in the health professions (pp. 3‐17). Edinburgh: Elsevier Ltd; 2008.
    1. Ilgen JS, Eva KW, Regehr G. What’s in a label? Is diagnosis the start or the end of clinical reasoning? J Gen Intern Med. 2016;31:435‐437. 10.1007/s11606-016-3592-7
    1. Audétat M‐C, Sader J, Cairo Notari S, et al. Understanding and promoting clinical reasoning in chronic and multimorbid conditions: a call for GPs and healthcare professionals. Health. 2019;11:1338‐1346. 10.4236/health.2019.1110103
    1. Hong QN, Pluye P, Fàbregues S, et al. Mixed Methods Appraisal Tool (MMAT), version 18, User guide. Registration of Copyright (#1148552), Canadian Intellectual Property Office, Industry Canada.
    1. Ailabouni NJ, Nishtala PS, Mangin D, Tordoff JM. General practitioners’ insight into deprescribing for the multimorbid older individual: a qualitative study. Int J Clin Pract. 2016;70:261‐276. 10.1111/ijcp.12780
    1. Anderson K, Foster M, Freeman C, Luetsch K, Scott I. Negotiating, “unmeasurable harm and benefit”: perspectives of general practitioners and consultant pharmacists on deprescribing in the primary care setting. Qual Health Res. 2017;27:1936‐1947. 10.1177/1049732316687732
    1. Anthierens S, Tansens A, Petrovic M, Christiaens T. Qualitative insights into general practitioners views on polypharmacy. BMC Fam Pract. 2010;11:65. 10.1186/1471-2296-11-65
    1. Borgström Bolmsjö B, Palagyi A, Keay L, Potter J, Lindley RI. Factors influencing deprescribing for residents in advanced care facilities: insights from general practitioners in Australia and Sweden. BMC Fam Pract. 2016;17:152. 10.1186/s12875-016-0551-7
    1. Carrier H, Zaytseva A, Bocquier A, et al. GPs’ management of polypharmacy and therapeutic dilemma in patients with multimorbidity: a cross‐sectional survey of GPs in France. Br J Gen Pract. 2019;69:e270‐e278. 10.3399/bjgp19X701801
    1. Clyne B, Cooper JA, Hughes CM, Fahey T, Smith SM. Smith SM and on behalf of the OPTI‐SCRIPT study team. 'Potentially inappropriate or specifically appropriate?' Qualitative evaluation of general practitioners views on prescribing, polypharmacy and potentially inappropriate prescribing in older people. BMC Fam Pract. 2016;17. 10.1186/s12875-016-0507-y
    1. Engberink AO, Pimouguet C, Amouyal M, Gerassimo O, Bourrel G, Berr C. Déterminants de la prise en charge des patients déments dépistés dans une cohort populationnelle : approche qualitative auprès de leurs médecins généralistes [Determinants of support for dementia patients in general practice: a qualitative approach based on an epidemiological cohort]. Geriatr Psychol Neuropsychiatr Vieil. 2013;11:157‐167. 10.1684/pnv.2013.0413
    1. Funk LM, Jolles SA, Greenberg CC, et al. Primary care physician decision making regarding severe obesity treatment and bariatric surgery: a qualitative study. Surg Obes Relat Dis. 2016;12:893‐902. 10.1016/j.soard.2015.11.028
    1. Hermush V, Daliot D, Weiss A, Brill S, Beloosesky Y. The impact of geriatric consultation on the care of the elders in community clinics. Arch Gerontol Geriatr. 2009;49:260‐262. 10.1016/j.archger.2008.09.007
    1. Herzog A, Gaertner B, Scheidt‐Nave C, Holzhausen M. ‘We can do only what we have the means for’general practitioners’ views of primary care for older people with complex health problems. BMC Fam Pract. 2015;16:35. 10.1186/s12875-015-0249-2
    1. Jansen J, McKinn S, Bonner C, et al. General practitioners' decision making about primary prevention of cardiovascular disease in older adults: a qualitative study. PLoS One. 2017;12(1):e0170228. 10.1371/journal.pone.0170228
    1. Kenning C, Fisher L, Bee P, Bower P, Coventry P. Primary care practitioner and patient understanding of the concepts of multimorbidity and self‐management: a qualitative study. SAGE Open Med. 2013;1:2050312113510001. 10.1177/2050312113510001
    1. Kristensen MAT, Hølge‐Hazelton B, Waldorff FB, Guassora AD. How general practitioners perceive and assess self‐care in patients with multiple chronic conditions: a qualitative study. BMC Fam Pract. 2017;18:109. 10.1186/s12875-017-0679-0
    1. Laursen J, Kornholt J, Betzer C, Petersen TS, Christensen MB. General practitioners’ barriers toward medication reviews in polymedicated multimorbid patients: how can a focus on the pharmacotherapy in an outpatient clinic support GPs? Health Serv Res Manag Epidemiol. 2018;5:1‐7. 10.1177/2333392818792169
    1. Loeb DF, Bayliss EA, Binswanger IA, Candrian C, Degruy FV. Primary care physician perceptions on caring for complex patients with medical and mental illness. J Gen Intern Med. 2012;27:945‐952. 10.1007/s11606-012-2005-9
    1. Luijks HD, Loeffen MJW, Lagro‐Janssen AL, Van Weel C, Lucassen PL, Schermer TR. GPs' considerations in multimorbidity management: a qualitative study. Br J Gen Pract. 2012;62:e503‐e510. 10.3399/bjgp12X652373
    1. Luijks HD, Lucassen PL, Van Weel C, Loeffen MJW, Lagro‐Janssen AL, Schermer TR. How GPs value guidelines applied to patients with multimorbidity: a qualitative study. BMJ Open. 2015;5:e007905. 10.1136/bmjopen-2015-007905
    1. Magin P, Goode S, Pond D. GPs, medications and older people: a qualitative study of general practitioners' approaches to potentially inappropriate medications in older people. Australas J Ageing. 2015;34:134‐139. 10.1111/ajag.12150
    1. Maio V, Jutkowitz E, Herrera K, Abouzaid S, Negri G, Del Canale S. Appropriate medication prescribing in elderly patients: how knowledgeable are primary care physicians? A survey study in Parma. Italy. J Clin Pharm Ther. 2011;36:468‐480. 10.1111/j.1365-2710.2010.01195.x
    1. Moen J, Norrgård S, Antonov K, Nilsson JLG, Ring L. GPs' perceptions of multiple‐medicine use in older patients. J Eval Clin Pract. 2010;16:69‐75. 10.1111/j.1365-2753.2008.01116.x
    1. Nixon M, Kousgaard MB. Organising medication discontinuation: a qualitative study exploring the views of general practitioners toward discontinuing statins. BMC Health Serv Res. 2016;16:226. 10.1186/s12913-016-1495-2
    1. Press Y, Punchik B, Kagan E, Barzak A, Freud T. Which factors affect the implementation of geriatric recommendations by primary care physicians? Isr J Health Policy Res. 2017;6:7. 10.1186/s13584-017-0134-7
    1. Quinodoz A, Déruaz‐Luyet A, N'Goran AA, Herzig L. Stratégies de priorisation dans la prise en charge des patients multimorbides en médecine de famille [Prioritization strategies in the care of multimorbid patients in family medicine]. Rev Med Suisse. 2016;12:928‐931.
    1. Schuling J, Gebben H, Veehof LJG, Haaijer‐Ruskamp FM. Deprescribing medication in very elderly patients with multimorbidity: the view of Dutch GPs. A qualitative study. BMC Fam Pract. 2012;13:56. 10.1186/1471-2296-13-56
    1. Sinnige J, Korevaar JC, van Lieshout J, Westert GP, Schellevis FG, Braspenning JC. Medication management strategy for older people with polypharmacy in general practice: a qualitative study on prescribing behaviour in primary care. Br J Gen Pract. 2016;66:e540‐e551. 10.3399/bjgp16X685681
    1. Sinnott C, Mc Hugh S, Boyce MB, Bradley CP. What to give the patient who has everything? A qualitative study of prescribing for multimorbidity in primary care. Br J Gen Pract. 2015;65:e184‐e191. 10.3399/bjgp15X684001
    1. Smith SM, O'Kelly S, O'Dowd T. GPs' and pharmacists' experiences of managing multimorbidity: a ‘Pandora's box’. Br J Gen Pract. 2010;60:e285‐e294. 10.3399/bjgp10X514756
    1. Vermunt NP, Elwyn G, Westert GP, Harmsen M, Rikkert MO, Meinders M. Goal setting is insufficiently recognised as an essential part of shared decision‐making in the complex care of older patients: a framework analysis. BMC Fam Pract. 2019;20:76. 10.1186/s12875-019-0966-z
    1. Vermunt NP, Harmsen M, Elwyn G, et al. A three‐goal model for patients with multimorbidity: a qualitative approach. Health Expect. 2018;21:528‐538. 10.1111/hex.12647
    1. Voigt K, Gottschall M, Köberlein‐Neu J, Schübel J, Quint N, Bergmann A. Why do family doctors prescribe potentially inappropriate medication to elderly patients? BMC Fam Pract. 2016;17:93. 10.1186/s12875-016-0482-3
    1. Wolf F, Freytag A, Schulz S, et al. German general practitioners’ self‐reported management of patients with chronic depression. BMC Psychiatry. 2017;17:401. 10.1186/s12888-017-1564-z
    1. Wrede J, Voigt I, Bleidorn J, Hummers‐Pradier E, Dierks ML, Junius‐Walker U. Complex health care decisions with older patients in general practice: patient‐centeredness and prioritization in consultations following a geriatric assessment. Patient Educ Couns. 2013;90:54‐60. 10.1016/j.pec.2012.07.015
    1. Audétat M‐C, Lubarsky S, Blais J‐G, Charlin B. Clinical reasoning: where do we stand on identifying and remediating difficulties? Creat Educ. 2013;4:42‐48. 10.4236/ce.2013.46A008
    1. Eva KW. What every teacher needs to know about clinical reasoning. Med Educ. 2005;39:98‐106. 10.1111/j.1365-2929.2004.01972.x
    1. Custers EJFM, Regehr G, Norman GR. Mental representations of medical diagnostic knowledge: a review. Acad Med. 1996;71:S55‐S61.
    1. Charlin B, Boshuizen HPA, Custers EJFM, Feltovich PJ. Scripts and clinical reasoning. Med Educ. 2007;41:1178‐1184. 10.1111/j.1365-2923.2007.02924.x
    1. Cook DA, Sherbino J, Durning SJ. Management reasoning: beyond the diagnosis. JAMA. 2018;319(22):2267‐2268. 10.1001/jama.2018.4385
    1. McBee E, Ratcliffe T, Picho K, et al. Contextual factors and clinical reasoning: differences in diagnostic and therapeutic reasoning in board certified versus resident physicians. BMC Med Educ. 2017;17:211. 10.1186/s12909-017-1041-x
    1. Kahneman D. Thinking, Fast and Slow. Farrar, Straus and Giroux; 2011.
    1. Norman G. Research in clinical reasoning: past history and current trends. Med Educ. 2005;39:418‐427. 10.1111/j.1365-2929.2005.02127.x
    1. Norman G. Dual processing and diagnostic errors. Adv Health Sci Educ Theory Pract. 2009;14:37‐49. 10.1007/s10459-009-9179-x
    1. Pelaccia T, Tardif J, Triby E, Charlin B. An analysis of clinical reasoning through a recent and comprehensive approach: the dual‐process theory. Med Educ Online. 2011;16:5890. 10.3402/meo.v16i0.5890
    1. Norman G, Monteiro S, Sherbino J. Is clinical cognition binary or continuous? Acad Med. 2013;88:1058‐1060. 10.1097/ACM.0b013e31829a3c32
    1. Stacey D, Légaré F, Pouliot S, Kryworuchko J, Dunn S. Shared decision making models to inform an interprofessional perspective on decision making: A theory analysis. Patient Educ Couns. 2010;80:164‐172. 10.1016/j.pec.2009.10.015
    1. Kiesewetter J, Fischer F, Fischer MR. Collaborative Clinical Reasoning—A Systematic Review of Empirical Studies. J Contin Educ Health Prof. 2017;37:123‐128. 10.1097/CEH.0000000000000158
    1. Col N, Bozzuto L, Kirkegaard P, et al. Interprofessional education about shared decision making for patients in primary care settings. J Interprof Care. 2011;25:409‐415. 10.3109/13561820.2011.619071
    1. Légaré F, Stacey D, Turcotte S, et al. Interventions for improving the adoption of shared decision making by healthcare professionals. Cochrane Database Syst Rev. 2014;15(9):CD006732. 10.1002/14651858.CD006732.pub3
    1. Couët N, Desroches S, Robitaille H, et al. Assessments of the extent to which health‐care providers involve patients indecision making: a systematic review of studies using the OPTION instrument. Health Expect. 2015;18:542‐561. 10.1111/hex.12054
    1. Politi MC, Clark MA, Ombao H, Dizon D, Elwyn G. Communicating uncertainty can lead to less decision satisfaction: a necessary cost of involving patients in shared decision making? Health Expect. 2011;14:84‐91. 10.1111/j.1369-7625.2010.00626.x
    1. Wagner EH. Chronic disease management: what will it take to improve care for chronic illness? Effect Clin Pract. 1998;1:2‐4.
    1. Wagner EH, Austin BT, Davis C, Hindmarsh M, Schaefer J, Bonomi A. Improving chronic illness care: translating evidence into action. Health Aff. 2001;20:64‐78. 10.1377/hlthaff.20.6.64
    1. Wilkerson L, Irby DM. Strategies for improving teaching practices: a comprehensive approach to faculty development. Acad Med. 1998;73:387‐396.
    1. Kilminster S, Cottrell D, Grant J, Jolly BAMEE. AMEE Guide No. 27: Effective educational and clinical supervision. Med Teach. 2007;29:2‐19. 10.1080/01421590701210907
    1. Irby DM. Excellence in clinical teaching: knowledge transformation and development required. Med Educ. 2014;48:776‐784. 10.1111/medu.12507
    1. Audétat M‐C, Laurin S, Dory V, Charlin B, Nendaz MR. Diagnosis and management of clinical reasoning difficulties: AMEE GUIDE 117. Dundee, UK: Association for Medical Education in Europe (AMEE); 2018.
    1. Dory V, Roex A. Let’s talk about thinking. Med Educ. 2012;46:1147‐1149. 10.1111/medu.12038
    1. Audétat M‐C, Laurin S, Dory V, Charlin B, Nendaz MR. Diagnosis and management of clinical reasoning difficulties: Part II. Clinical reasoning difficulties: Management and remediation strategies. Med Teach. 2017;39:797‐801. 10.1080/0142159X.2017.1331034
    1. Nendaz MR, Perrier A. Diagnostic errors and flaws in clinical reasoning: mechanisms and prevention in practice. Swiss Med Wkly. 2012;142:w13706. 10.4414/smw.2012.13706

Source: PubMed

3
Abonnieren