[Long-term outcomes of children treated with continuous renal replacement therapy]
S Almarza, K Bialobrzeska, M M Casellas, M J Santiago, J López-Herce, B Toledo, Á Carrillo, S Almarza, K Bialobrzeska, M M Casellas, M J Santiago, J López-Herce, B Toledo, Á Carrillo
Abstract
Introduction: The objective of this study is to analyze long-term outcomes and kidney function in children requiring continuous renal replacement therapy (CRRT) after an acute kidney injury episode.
Patients and methods: A retrospective observational study was performed using a prospective database of 128 patients who required CRRT admitted to the pediatric intensive care unit between years 2006 and 2012. The subsequent outcomes were assessed in those surviving at hospital discharge.
Results: Of the 128 children who required RRT in the pediatric intensive care unit, 71 survived at hospital discharge (54.4%), of whom 66 (92.9%) were followed up. Three patients had chronic renal failure prior to admission to the NICU. Of the 63 remaining patients, 6 had prolonged or relapses of renal function disturbances, but only one patient with atypical Hemolytic Uremic Syndrome developed end-stage renal failure. The rest had normal kidney function at the last check-up.
Conclusions: Most of surviving children that required CRRT have a positive outcome later on, presenting low mortality rates and recovery of kidney function in the medium term.
Keywords: Acute kidney injury; Acute renal failure; Chronic renal failure; Continuous renal replacement therapy; Daño renal agudo; Insuficiencia renal aguda; Insuficiencia renal crónica; Técnicas de depuración extrarrenal continua.
Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.
Source: PubMed