Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations

Thomas W Wainwright, Mike Gill, David A McDonald, Robert G Middleton, Mike Reed, Opinder Sahota, Piers Yates, Olle Ljungqvist, Thomas W Wainwright, Mike Gill, David A McDonald, Robert G Middleton, Mike Reed, Opinder Sahota, Piers Yates, Olle Ljungqvist

Abstract

Background and purpose - There is a large volume of heterogeneous studies across all Enhanced Recovery After Surgery (ERAS®) components within total hip and total knee replacement surgery. This multidisciplinary consensus review summarizes the literature, and proposes recommendations for the perioperative care of patients undergoing total hip replacement and total knee replacement with an ERAS program.Methods - Studies were selected with particular attention being paid to meta-analyses, randomized controlled trials, and large prospective cohort studies that evaluated the efficacy of individual items of the perioperative treatment pathway to expedite the achievement of discharge criteria. A consensus recommendation was reached by the group after critical appraisal of the literature.Results - This consensus statement includes 17 topic areas. Best practice includes optimizing preoperative patient education, anesthetic technique, and transfusion strategy, in combination with an opioid-sparing multimodal analgesic approach and early mobilization. There is insufficient evidence to recommend that one surgical technique (type of approach, use of a minimally invasive technique, prosthesis choice, or use of computer-assisted surgery) over another will independently effect achievement of discharge criteria.Interpretation - Based on the evidence available for each element of perioperative care pathways, the ERAS® Society presents a comprehensive consensus review, for the perioperative care of patients undergoing total hip replacement and total knee replacement surgery within an ERAS® program. This unified protocol should now be further evaluated in order to refine the protocol and verify the strength of these recommendations.

References

    1. Aasvang E K, Luna I E, Kehlet H. Challenges in postdischarge function and recovery: the case of fast-track hip and knee arthroplasty. Br J Anaesth 2015; 115(6): 861–6.
    1. Aboltins C A, Berdal J E, Casas F, Corona P S, Cuellar D, Farrari M C, Hendershot E, Huang W, Kuo F-C, Malkani A, Reyes F, Rudelli S, Safir O, Seyler T, Tan T L, Townsend R, Tuncay I, Turner D, Winkler H, Wouthuyzen-Bakker M, Yates A J, Zahar A. Hip and Knee Section, Prevention, Antimicrobials (Systemic): Proceedings of International Consensus on Orthopedic Infections. J Arthoplasty 2019; 34(2): S279–S288.
    1. Affas F, Nygards E B, Stiller C O, Wretenberg P, Olofsson C. Pain control after total knee arthroplasty: a randomized trial comparing local infiltration anesthesia and continuous femoral block. Acta Orthop 2011; 82(4): 441–7.
    1. Aggarwal V K, Elbuluk A, Dundon J, Herrero C, Hernandez C, Schwarzkopf R, Iorio R, Long W J. Surgical approach significantly affects the complication rates associated with total hip arthroplasty. Bone Joint J 2019; 101-B(6): 646–51.
    1. AlBuhairan B, Hind D, Hutchinson A. Antibiotic prophylaxis for wound infections in total joint arthroplasty: a systematic review. J Bone Joint Surg Br 2008; 90(7): 915–19.
    1. Andersen L O, Kehlet H. Analgesic efficacy of local infiltration analgesia in hip and knee arthroplasty: a systematic review. Br J Anaesth 2014; 113(3): 360–74.
    1. Apfel C C, Laara E, Koivuranta M, Greim C A, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers. Anesthesiology 1999; 91(3): 693–700.
    1. Apfel C C, Korttila K, Abdalla M, Kerger H, Turan A, Vedder I, Zernak C, Danner K, Jokela R, Pocock S J, Trenkler S, Kredel M, Biedler A, Sessler D I, Roewer N, Investigators I. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med 2004; 350(24): 2441–51.
    1. Apfel C C, Turan A, Souza K, Pergolizzi J, Hornuss C. Intravenous acetaminophen reduces postoperative nausea and vomiting: a systematic review and meta-analysis. Pain 2013; 154(5): 677–89.
    1. Awad S, Varadhan K K, Ljungqvist O, Lobo D N. A meta-analysis of randomised controlled trials on preoperative oral carbohydrate treatment in elective surgery. Clin Nutr 2013; 32(1): 34–44.
    1. Balderi T, Carli F. Urinary retention after total hip and knee arthroplasty. Minerva Anestesiol 2010; 76(2): 120–30.
    1. Bandholm T, Wainwright T W, Kehlet H. Rehabilitation strategies for optimisation of functional recovery after major joint replacement. J Exp Orthop 2018; 5(1): 44.
    1. Berend K R, Lombardi A V, Berend M E, Adams J B, Morris M J. The outpatient total hip arthroplasty. Bone Joint J 2018; 100-B(1 Suppl. A): 31–5.
    1. Bergin C, Speroni K G, Travis T, Bergin J, Sheridan M J, Kelly K, Daniel M G. Effect of preoperative incentive spirometry patient education on patient outcomes in the knee and hip joint replacement population. J Perianesth Nurs 2014; 29(1): 20–7.
    1. Best M J, Buller L T, Gosthe R G, Klika A K, Barsoum W K. Alcohol misuse is an independent risk factor for poorer postoperative outcomes following primary total hip and total knee arthroplasty. J Arthroplasty 2015; 30(8): 1293–8.
    1. Bjerregaard L S, Hornum U, Troldborg C, Bogoe S, Bagi P, Kehlet H. Postoperative urinary catheterization thresholds of 500 versus 800 ml after fast-track total hip and knee arthroplasty: a randomized, open-label, controlled trial. Anesthesiology 2016a; 124(6): 1256–64.
    1. Bjerregaard L S, Jorgensen C C, Kehlet H, Lundbeck Foundation Centre for Fast-Track H, Knee Replacement Collaborative G. Serious renal and urological complications in fast-track primary total hip and knee arthroplasty; a detailed observational cohort study. Minerva Anestesiol 2016b [Epub ahead of print]
    1. Bohm E, Zhu N, Gu J, de Guia N, Linton C, Anderson T, Paton D, Dunbar M. Does adding antibiotics to cement reduce the need for early revision in total knee arthroplasty? Clin Orthop Relat Res 2014; 472(1): 162–8.
    1. Brydone A S, Souvatzoglou R, Abbas M, Watson D G, McDonald D A, Gill A M. Ropivacaine plasma levels following high-dose local infiltration analgesia for total knee arthroplasty. Anaesthesia 2015; 70(7): 784–90.
    1. Buvanendran A, Kroin J S, Tuman K J, Lubenow T R, Elmofty D, Moric M, Rosenberg AG. Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial. JAMA 2003; 290(18): 2411–8.
    1. Carli F, Scheede-Bergdahl C. Prehabilitation to enhance perioperative care. Anesthesiol Clin 2015; 33(1): 17–33.
    1. Carli F, Zavorsky G S. Optimizing functional exercise capacity in the elderly surgical population. Curr Opin Clin Nutr Metab Care 2005; 8(1): 23–32.
    1. Cerantola Y, Valerio M, Persson B, Jichlinski P, Ljungqvist O, Hubner M, Kassouf W, Muller S, Baldini G, Carli F, Naesheimh T, Ytrebo L, Revhaug A, Lassen K, Knutsen T, Aarsether E, Wiklund P, Patel H R. Guidelines for perioperative care after radical cystectomy for bladder cancer: Enhanced Recovery After Surgery (ERAS((R))) society recommendations. Clin Nutr 2013; 32(6): 879–87.
    1. Chan E Y, Fransen M, Parker D A, Assam P N, Chua N. Femoral nerve blocks for acute postoperative pain after knee replacement surgery. Cochrane Database Syst Rev 2014(5): CD009941.
    1. Chen H, Li S, Ruan T, Liu L, Fang L. Is it necessary to perform prehabilitation exercise for patients undergoing total knee arthroplasty: meta-analysis of randomized controlled trials. Phys Sportsmed 2018; 46(1): 36–43. doi: 0.1080/00913847.2018.1403274.
    1. Choi P T, Bhandari M, Scott J, Douketis J. Epidural analgesia for pain relief following hip or knee replacement. Cochrane Database Syst Rev 2003(3): CD003071.
    1. Clarke H, Soneji N, Ko D T, Yun L, Wijeysundera D N. Rates and risk factors for prolonged opioid use after major surgery: population based cohort study. BMJ 2014; 348:g1251.
    1. Cole P J, Craske D A, Wheatley R G. Efficacy and respiratory effects of low-dose spinal morphine for postoperative analgesia following knee arthroplasty. Br J Anaesth 2000; 85(2): 233–7.
    1. Dale H, Hallan G, Hallan G, Espehaug B, Havelin L I, Engesaeter L B. Increasing risk of revision due to deep infection after hip arthroplasty. Acta Orthop 2009; 80(6): 639–45.
    1. de Beer Jde V, Winemaker M J, Donnelly G A, Miceli P C, Reiz J L, Harsanyi Z, Payne L W, Darke A C. Efficacy and safety of controlled-release oxycodone and standard therapies for postoperative pain after knee or hip replacement. Can J Surg 2005; 48(4): 277–83.
    1. den Hartog Y M, Mathijssen N M, Vehmeijer S B. Reduced length of hospital stay after the introduction of a rapid recovery protocol for primary THA procedures. Acta Orthop 2013; 84(5): 444–7.
    1. Dennis D A, Kittelson A J, Yang C C, Miner T M, Kim R H, Stevens-Lapsley J E. Does Tourniquet use in TKA affect recovery of lower extremity strength and function? A randomized trial. Clin Orthop Relat Res 2016; 474(1): 69–77.
    1. Dort J C, Farwell D G, Findlay M, Huber G F, Kerr P, Shea-Budgell M A, Simon C, Uppington J, Zygun D, Ljungqvist O, Harris J. Optimal perioperative care in major head and neck cancer surgery with free flap reconstruction: a consensus review and recommendations from the Enhanced Recovery After Surgery Society. JAMA Otolaryngol Head Neck Surg 2017; 143(3): 292–303.
    1. Eberhart L H, Mauch M, Morin A M, Wulf H, Geldner G. Impact of a multimodal anti-emetic prophylaxis on patient satisfaction in high-risk patients for postoperative nausea and vomiting. Anaesthesia 2002; 57(10): 1022–7.
    1. Engesaeter L B, Espehaug B, Lie SA, Furnes O, Havelin LI. Does cement increase the risk of infection in primary total hip arthroplasty? Revision rates in 56,275 cemented and uncemented primary THAs followed for 0–16 years in the Norwegian Arthroplasty Register. Acta Orthop 2006; 77(3): 351–8.
    1. Group. ERAS Compliance The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results form an international registry. Ann Surg 2015; 261(6): 153–9.
    1. Falck-Ytter Y, Francis C W, Johanson N A, Curley C, Dahl O E, Schulman S, Ortel T L, Pauker S G, Colwell C W, Jr. . Prevention of VTE in orthopedic surgery patients. Antithrombotic therapy and prevention of thrombosis, 9th ed. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141(2 Suppl.): e278S–e325S.
    1. Fernandez M A, Karthikeyan S, Wyse M, Foguet P. The incidence of postoperative urinary retention in patients undergoing elective hip and knee arthroplasty. Ann R Coll Surg Engl 2014; 96(6): 462–5.
    1. Fischer H B, Simanski C J, Sharp C, Bonnet F, Camu F, Neugebauer E A, Rawal N, Joshi G P, Schug S A, Kehlet H, Group P W. A procedure-specific systematic review and consensus recommendations for postoperative analgesia following total knee arthroplasty. Anaesthesia 2008; 63(10): 1105–23.
    1. Fowler S J, Symons J, Sabato S, Myles P S. Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials. Br J Anaesth 2008; 100(2): 154–64.
    1. Gan T J, Diemunsch P, Habib A S, Kovac A, Kranke P, Meyer T A, Watcha M, Chung F, Angus S, Apfel C C, Bergese S D, Candiotti K A, Chan M T, Davis P J, Hooper V D, Lagoo-Deenadayalan S, Myles P, Nezat G, Philip B K, Tramer M R, Society for Ambulatory A. Consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg 2014; 118(1): 85–113.
    1. Gehling M, Tryba M. Risks and side-effects of intrathecal morphine combined with spinal anaesthesia: a meta-analysis. Anaesthesia 2009; 64(6): 643–51.
    1. Goyal N, Chen A F, Padgett S E, Tan T L, Kheir M M, Hopper R H, Hamilton W G, Hozack W J. A. multicenter, randomized study of outpatient versus inpatient total hip arthroplasty. Clin Orthop Relat Res 2017; 475(2): 364–372.
    1. Gromov K, Kjaersgaard-Andersen P, Revald P, Kehlet H, Husted H. Feasibility of outpatient total hip and knee arthroplasty in unselected patients. Acta Orthop 2017; 88(5): 516–21.
    1. Guerra M L, Singh P J, Taylor N F. Early mobilization of patients who have had a hip or knee joint replacement reduces length of stay in hospital: a systematic review. Clin Rehabil 2015; 29(9): 844–54.
    1. Guler O, Mahirogullari M, Isyar M, Piskin A, Yalcin S, Mutlu S, Sahin B. Comparison of quadriceps muscle volume after unilateral total knee arthroplasty with and without tourniquet use. Knee Surg Sports Traumatol Arthrosc 2016; 24: 2595. .
    1. Gustafsson U O, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J, Enhanced Recovery After Surgery Study G. Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 2011; 146(5): 571–7.
    1. Gustafsson U O, Scott M J, Schwenk W, Demartines N, Roulin D, Francis N, McNaught C E, Macfie J, Liberman A S, Soop M, Hill A, Kennedy R H, Lobo D N, Fearon K, Ljungqvist O, Enhanced Recovery After Surgery Society fPC, European Society for Clinical N, Metabolism, International Association for Surgical M, Nutrition. Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS((R))) Society recommendations. World J Surg 2013; 37(2): 259–84.
    1. Guyatt G H, Oxman A D, Vist G E, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schunemann H J, Group GW. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008; 336(7650): 924–6.
    1. Hamilton T W, Strickland L H, Pandit H G. A meta-analysis on the use of gabapentinoids for the treatment of acute postoperative pain following total knee arthroplasty. J Bone Joint Surg Am 2016; 98(16): 1340–50.
    1. Han C, Li X D, Jiang HQ, Ma J X, Ma X L. The use of gabapentin in the management of postoperative pain after total hip arthroplasty: a meta-analysis of randomised controlled trials. J Orthop Surg Res 2016a; 11(1): 79.
    1. Han C, Li X D, Jiang H Q, Ma J X, Ma X L. The use of gabapentin in the management of postoperative pain after total knee arthroplasty: A PRISMA-compliant meta-analysis of randomized controlled trials [published correction appears in Medicine (Baltimore). 2016; 95(28): e0916]. Medicine (Baltimore). 2016; 95(23): e3883.
    1. Hansen T B, Bredtoft H K, Larsen K. Preoperative physical optimization in fast-track hip and knee arthroplasty. Dan Med J 2012; 59(2): A4381.
    1. Harper C M, Lyles Y M. Physiology and complications of bed rest. J Am Geriatr Soc 1988; 36(11): 1047–54.
    1. Harsten A, Hjartarson H, Toksvig-Larsen S. Total hip arthroplasty and perioperative oral carbohydrate treatment: a randomised, double-blind, controlled trial. Eur J Anaesthesiol 2012; 29(6): 271–4.
    1. Harsten A, Kehlet H, Toksvig-Larsen S. Recovery after total intravenous general anaesthesia or spinal anaesthesia for total knee arthroplasty: a randomized trial. Br J Anaesth 2013; 111(3): 391–9.
    1. Harsten A, Bandholm T, Kehlet H, Toksvig-Larsen S. Tourniquet versus no tourniquet on knee-extension strength early after fast-track total knee arthroplasty; a randomized controlled trial. Knee 2015a; 22(2): 126–30.
    1. Harsten A, Kehlet H, Ljung P, Toksvig-Larsen S. Total intravenous general anaesthesia vs. spinal anaesthesia for total hip arthroplasty. Acta Anaesthesiol Scand 2015b; 59(4): 542–3.
    1. Henry D A, Carless P A, Moxey A J, O’Connell D, Stokes B J, Fergusson D A, Ker K.. Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev 2011(3): CD001886.
    1. Hinarejos P, Guirro P, Puig-Verdie L, Torres-Claramunt R, Leal-Blanquet J, Sanchez-Soler J, Monllau J C. Use of antibiotic-loaded cement in total knee arthroplasty. World J Orthop 2015; 6(11): 877–85.wjo.v6.i11.877.
    1. Holte K, Kristensen B B, Valentiner L, et al. . Liberal versus restrictive fluid management in knee arthroplasty: a randomized, double-blind study. Anesth Analg 2007; 105(2): 465–74.
    1. Huang Y M, Wang C M, Wang C T, Lin W P, Horng L C, Jiang C C. Perioperative celecoxib administration for pain management after total knee arthroplasty: a randomized, controlled study. BMC Musculoskelet Disord 2008; 9: 77.
    1. Huang Z, Ma J, Shen B, Pei F. General anesthesia: to catheterize or not? A prospective randomized controlled study of patients undergoing total knee arthroplasty. J Arthroplasty 2015; 30(3): 502–6.
    1. Husted H. Fast-track hip and knee arthroplasty: clinical and organizational aspects. Acta Orthop 2012; 83(346 Suppl.): 1–39.
    1. Husted H, Otte K S, Kristensen B B, Orsnes T, Wong C, Kehlet H. Low risk of thromboembolic complications after fast-track hip and knee arthroplasty. Acta Orthop 2010; 81(5): 599–605.
    1. Husted H, Lunn T H, Troelsen A, Gaarn-Larsen L, Kristensen B B, Kehlet H. Why still in hospital after fast-track hip and knee arthroplasty? Acta Orthop 2011; 82(6): 679–84.
    1. Husted H, Gromov K, Malchau H, Freiberg A, Gebuhr P, Troelsen A. Traditions and myths in hip and knee arthroplasty. Acta Orthop 2014; 85(6): 548–55.
    1. Ibrahim M S, Alazzawi S, Nizam I, Haddad F S. An evidence-based review of enhanced recovery interventions in knee replacement surgery. Ann R Coll Surg Engl 2013a; 95(6): 386–9.
    1. Ibrahim M S, Twaij H, Giebaly D E, Nizam I, Haddad F S. Enhanced recovery in total hip replacement: a clinical review. Bone Joint J 2013b; 95-B(12): 1587–94.
    1. Ilfeld B M, Duke K B, Donohue M C. The association between lower extremity continuous peripheral nerve blocks and patient falls after knee and hip arthroplasty. Anesth Analg 2010; 111(6): 1552–4.
    1. Jaeger P, Nielsen Z J, Henningsen M H, Hilsted K L, Mathiesen O, Dahl J B. Adductor canal block versus femoral nerve block and quadriceps strength: a randomized, double-blind, placebo-controlled, crossover study in healthy volunteers. Anesthesiology 2013; 118(2): 409–15.
    1. Jia F, Guo B, Xu F, Hou Y, Tang X, Huang L. A comparison of clinical, radiographic and surgical outcomes of total hip arthroplasty between direct anterior and posterior approaches: a systematic review and meta-analysis. Hip Int 2019; 29(6): 584–96.
    1. Jordan R W, Smith N A, Chahal G S, Casson C, Reed M R, Sprowson A P. Enhanced education and physiotherapy before knee replacement; is it worth it? A systematic review. Physiotherapy 2014; 100(4): 305–12.
    1. Jorgensen C C, Kehlet H, Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group . Outcomes in smokers and alcohol users after fast-track hip and knee arthroplasty. Acta Anaesthesiol Scand 2013; 57(5): 631–8.
    1. Jorgensen C C, Kehlet H, Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group. Early thromboembolic events </=1week after fast-track total hip and knee arthroplasty. Thromb Res 2016; 138: 37–42.
    1. Jorgensen C C, Jacobsen M K, Soeballe K, Hansen T B, Husted H, Kjaersgaard-Andersen P, Hansen L T, Laursen M B, Kehlet H. Thromboprophylaxis only during hospitalisation in fast-track hip and knee arthroplasty, a prospective cohort study. BMJ Open 2013; 3(12): e003965.
    1. Juelsgaard P, Larsen U T, Sorensen J V, Madsen F, Soballe K. Hypotensive epidural anesthesia in total knee replacement without tourniquet: reduced blood loss and transfusion. Reg Anesth Pain Med 2001; 26(2): 105–10.
    1. Kandasami M, Kinninmonth A W, Sarungi M, Baines J, Scott N B. Femoral nerve block for total knee replacement: a word of caution. Knee 2009; 16(2): 98–100.
    1. Kehlet H. Fast-track hip and knee arthroplasty. Lancet 2013; 381(9878): 1600–2.
    1. Kehlet H, Aasvang E K. Regional or general anesthesia for fast-track hip and knee replacement: what is the evidence? F1000Res 2015; 4.f1000research.7100.1.
    1. Kelly E G, Cashman J P, Imran F H, Conroy R, O’Byrne J. Systematic review and meta-analysis of closed suction drainage versus non-drainage in primary hip arthroplasty. Surg Technol Int 2014; 24: 295–301.
    1. Khan S K, Malviya A, Muller S D, Carluke I, Partington P F, Emmerson K P, Reed M R. Reduced short-term complications and mortality following enhanced recovery primary hip and knee arthroplasty: results from 6,000 consecutive procedures. Acta Orthop 2014; 85(1): 26–31.
    1. Koc B B, Schotanus M G M, Kollenburg J P, Janssen M J A, Tijssen F, Jansen E J P. Effectiveness of early warming with self-warming blankets on post op hypothermia in total hip and knee arthroplasty. Orthop Nurs 2017; 33(1): 356–60.
    1. Lassen K, Coolsen M M, Slim K, Carli F, de Aguilar-Nascimento J E, Schafer M, Parks R W, Fearon K C, Lobo D N, Demartines N, Braga M, Ljungqvist O, Dejong C H, Society E, European Society for Clinical N, Metabolism, International Association for Surgical M, Nutrition. Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. Clin Nutr 2012; 31(6): 817–30.
    1. Li B, Wen Y, Wu H, Qian Q, Lin X, Zhao H. The effect of tourniquet use on hidden blood loss in total knee arthroplasty. Int Orthop 2009; 33(5): 1263–8.
    1. Liu X, Zhang X, Chen Y, Wang Q, Jiang Y, Zeng B. Hidden blood loss after total hip arthroplasty. J Arthroplasty 2011; 26(7): 1100–5 e1.
    1. Liu P L, Li D Q, Zhang Y K, Lu Q S, Ma L, Bao X Z. Effects of unilateral tourniquet used in patients undergoing simultaneous bilateral total knee arthroplasty. Orthop Sug 2017; 9(2): 180–5.
    1. Ljunggren S, Hahn R G. Oral nutrition or water loading before hip replacement surgery: a randomized clinical trial. Trials 2012; 13: 97.
    1. Ljungqvist O, Scott M, Fearon K C. Enhanced Recovery After Surgery: a review. JAMA Surg 2017; 152(3): 292–8.
    1. Louw A, Diener I, Butler D S, Puentedura E J. Preoperative education addressing postoperative pain in total joint arthroplasty: review of content and educational delivery methods. Physiother Theory Pract 2013; 29(3): 175–94.
    1. Lunn T H, Kristensen B B, Andersen L O, et al. . Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial. Br J Anesth 2011; 106(2): 230–8.
    1. Lunn T H, Husted H, Laursen M B, Hansen L T, Kehlet H. Analgesic and sedative effects of perioperative gabapentin in total knee arthroplasty: a randomized, double blind, placebo-controlled dose-finding study. Pain 2015; 156(12): 2438–48.
    1. Mak J C, Fransen M, Jennings M, March L, Mittal R, Harris I A, National H, Medical Research Council of A. Evidence-based review for patients undergoing elective hip and knee replacement. ANZ J Surg 2014; 84(1-2): 17–24.
    1. Malviya A, Martin K, Harper I, Muller S D, Emmerson K P, Partington P F, Reed M R. Enhanced recovery program for hip and knee replacement reduces death rate. Acta Orthop 2011; 82(5): 577–81.
    1. Mao Y, Wu L, Ding W. The efficacy of preoperative administration of gabapentin/pregabalin in improving pain after total hip arthroplasty: a meta-analysis. BMC Musculoskelet Disord 2016; 17(1): 373.
    1. Mathiesen O, Jacobsen L S, Holm H E, Randall S, Adamiec-Malmstroem L, Graungaard B K, et al. . Pregabalin and dexamethasone for postoperative pain control: a randomized controlled study in hip arthroplasty. Br J Anaesth 2008; 101(4): 535–41.
    1. McCartney C J L, McLeod G A. Local infiltration analgesia for total knee arthroplasty. Br J Anaesth 2011; 107(4): 487–9.
    1. McDonald D A, Siegmeth R, Deakin A H, Kinninmonth A W, Scott N B. An enhanced recovery programme for primary total knee arthroplasty in the United Kingdom: follow up at one year. Knee 2012; 19(5): 525–9.
    1. McDonald S, Page M J, Beringer K, Wasiak J, Sprowson A. Preoperative education for hip or knee replacement. Cochrane Database Syst Rev 2014(5): CD003526.
    1. McDonald D A, Deakin A H, Ellis B M, Robb Y, Howe T E, Kinninmonth A W, Scott N B. The technique of delivery of peri-operative analgesia does not affect the rehabilitation or outcomes following total knee arthroplasty. Bone Joint J 2016; 98-B(9): 1189–96.
    1. McGovern P D, Albrecht M, Belani K G, Nachtsheim C, Partington P F, Carluke I, et al. . Forced air-warming and ultra-clean ventilation do not mix. J Bone Joint Surg Br 2011; 93-B: 1537–44.
    1. Melloul E, Hubner M, Scott M, Snowden C, Prentis J, Dejong C H, Garden O J, Farges O, Kokudo N, Vauthey J N, Clavien P A, Demartines N. Guidelines for perioperative care for liver surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations. World J Surg 2016; 40(10): 2425–40.
    1. Memtsoudis S G, Sun X, Chiu YL, Stundner O, Liu S S, Banerjee S, Mazumdar M, Sharrock N E. Perioperative comparative effectiveness of anesthetic technique in orthopedic patients. Anesthesiology 2013; 118(5): 1046–58.
    1. Meunier A, Lisander B, Good L. Effects of celecoxib on blood loss, pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial. Acta Orthop 2007; 78(5): 661–7.
    1. Mills E, Eyawo O, Lockhart I, Kelly S, Wu P, Ebbert J O. Smoking cessation reduces postoperative complications: a systematic review and meta-analysis. Am J Med 2011; 124(2): 144–54 e8.
    1. Moiniche S, Kehlet H, Dahl J B. A qualitative and quantitative systematic review of preemptive analgesia for postoperative pain relief: the role of timing of analgesia. Anesthesiology 2002; 96(3): 725–41.
    1. Moller A M, Villebro N, Pedersen T, Tonnesen H. Effect of preoperative smoking intervention on postoperative complications: a randomised clinical trial. Lancet 2002; 359(9301): 114–17.
    1. Mortensen K, Nilsson M, Slim K, Schafer M, Mariette C, Braga M, Carli F, Demartines N, Griffin S M, Lassen K, Enhanced Recovery After Surgery G. Consensus guidelines for enhanced recovery after gastrectomy: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. Br J Surg 2014; 101(10): 1209–29.
    1. Moyer R, Ikert K, Long K, Marsh J. The value of preoperative exercise and education for patients undergoing total hip and knee arthroplasty: a systematic review and meta-analysis. JBJS Rev 2017; 5(12): e2.
    1. Munoz M, Gomez-Ramirez S, Cuenca J, Garcia-Erce J A, Iglesias-Aparicio D, Haman-Alcober S, Ariza D, Naveira E. Very-short-term perioperative intravenous iron administration and postoperative outcome in major orthopedic surgery: a pooled analysis of observational data from 2547 patients. Transfusion 2014; 54(2): 289–99.
    1. Munoz M, Acheson A G, Auerbach M, Besser M, Habler O, Kehlet H, Liumbruno G M, Lasocki S, Meybohm P, Rao Baikady R, Richards T, Shander A, So-Osman C, Spahn D R, Klein A A. International consensus statement on the peri-operative management of anaemia and iron deficiency. Anaesthesia 2017; 72(2): 233–47.
    1. Munoz M, Acheson A G, Bisbe E, Butcher A, Gomez-Ramirez S, Khalafallah A A, Kehlet H, Kietaibl S, Liumbruno G M, Meybohm P, Rao Baikady R, Shander A, So-Osman C, Spahn D R, Klein A A. An international consensus statement on the management of postoperative anaemia after major surgical procedures. Anaesthesia 2018; 73(11): 1418–31.
    1. National Institute of Health and Care Excellence (NICE ). Hypothermia: prevention and management in adults having surgery. Clinical Guidelines 2016. Available from:
    1. National Institute of Health and Care Excellence (NICE ). Intravenous fluid therapy in adults in hospital 2017. Available from:
    1. National Institute of Health and Care Excellence (NICE ). Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. Clinical guideline NG89. 2018. Available from: .
    1. Newman J H, Bowers M, Murphy J. The clinical advantages of autologous transfusion: a randomized, controlled study after knee replacement. J Bone Joint Surg Br 1997; 79(4): 630–2.
    1. Nielsen C S, Jans O, Orsnes T, Foss N B, Troelsen A, Husted H. Combined intra-articular and intravenous tranexamic acid reduces blood loss in total knee arthroplasty: a randomized, double-blind, placebo-controlled trial. J Bone Joint Surg Am 2016; 98(10): 835–41.
    1. Nygren J. The metabolic effects of fasting and surgery. Best Pract Res Clin Anaesthesiol 2006; 20(3): 429–38.
    1. Nygren J, Soop M, Thorell A, Sree Nair K, Ljungqvist O. Preoperative oral carbohydrates and postoperative insulin resistance. Clin Nutr 1999; 18(2): 117–20.
    1. Nygren J, Thacker J, Carli F, Fearon K C, Norderval S, Lobo D N, Ljungqvist O, Soop M, Ramirez J, Enhanced Recovery After Surgery S. Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. Clin Nutr 2012; 31(6): 801–16.
    1. Ong C K, Seymour R, Lirk P, Merry A. Combining paracetamol (acetaminophen) with nonsteroidal anti-inflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain. Anesthes Analg 2010; 110(4): 1170–9.
    1. Oppedal K, Moller A M, Pedersen B, Tonnesen H. Preoperative alcohol cessation prior to elective surgery. Cochrane Database Syst Rev 2012(7): CD008343.
    1. Parker M J, Livingstone V, Clifton R, McKee A. Closed suction surgical wound drainage after orthopaedic surgery. Cochrane Database Syst Rev 2007(3): CD001825.
    1. Paul J E, Arya A, Hurlburt L, Cheng J, Thabane L, Tidy A, Murthy Y. Femoral nerve block improves analgesia outcomes after total knee arthroplasty: a meta-analysis of randomized controlled trials. Anesthesiology 2010; 113(5): 1144–62.
    1. Perlas A, Kirkham K R, Billing R, Tse C, Brull R, Gandhi R, Chan V W. The impact of analgesic modality on early ambulation following total knee arthroplasty. Reg Anesth Pain Med 2013; 38(4): 334–9.
    1. Petersen P B, Kehlet H, Jorgensen CC, Lundbeck Foundation Centre for Fast-track H , Knee Replacement Collaborative G. Safety of in-hospital only thromboprophylaxis after fast-track total hip and knee arthroplasty: a prospective follow-up study in 17,582 procedures. Thromb Haemost 2018a; 118(12): 2152–61.
    1. Petersen K K, Lunn T H, Husted H, et al. . The influence of pre- and perioperative administration of gabapentin on pain 3–4 years after total knee arthroplasty. Scand J Pain 2018b; 18(2): 237–45.
    1. Prasad N, Padmanabhan V, Mullaji A. Blood loss in total knee arthroplasty: an analysis of risk factors. Int Orthop 2007; 31(1): 39–44.
    1. Pujol-Nicolas A, Morrison R, Casson C, et al. . Preoperative screening and intervention for mild anemia with low iron stores in elective hip and knee arthroplasty. Transfusion 2017; 57(12): 3049–57.
    1. Quinn M, Bowe A, Galvin R, Dawson P, O’Byrne J. The use of postoperative suction drainage in total knee arthroplasty: a systematic review. Int Orthop 2015; 39(4): 653–8.
    1. Rajesparan K, Biant L C, Ahmad M, Field R E. The effect of an intravenous bolus of tranexamic acid on blood loss in total hip replacement. J Bone Joint Surg Br 2009; 91(6): 776–83.
    1. Rawal N. Epidural technique for postoperative pain: gold standard no more? Reg Anesth Pain Med 2012; 37(3): 310–17.
    1. Rothwell M P, Pearson D, Hunter J D, Mitchell P A, Graham-Woollard T, Goodwin L, Dunn G. Oral oxycodone offers equivalent analgesia to intravenous patient-controlled analgesia after total hip replacement: a randomized, single-centre, non-blinded, non-inferiority study. Br J Anaesth 2011; 106(6): 865–72.
    1. Sah A P. Hyponatremia after primary hip and knee arthroplasty: incidence and associated risk factors. Am J Orthop (Belle Mead NJ) 2014; 43(4): E69–73.
    1. Scott N B, McDonald D, Campbell J, et al. . The use of enhanced recovery after surgery (ERAS) principles in Scottish orthopaedic units: an implementation and follow-up at 1 year 2010-2011: a report from the Musculoskeletal Audit, Scotland. Arch Orthop Trauma Surg 2013; 133(1): 117–24: 10.1007/s00402-012-1619-z.
    1. Shang J, Wang H, Zheng B, Rui M, Wang Y. Combined intravenous and topical tranexamic acid versus intravenous use alone in primary total knee and hip arthroplasty: a meta-analysis of randomized controlled trials. Int J Surg 2016; 36(Pt A): 324–9.
    1. Sharma S, Iorio R, Specht L M, Davies-Lepie S, Healy W L. Complications of femoral nerve block for total knee arthroplasty. Clin Orthop Relat Res 2010; 468(1): 135–40.
    1. Sinatra R S, Jahr J S, Reynolds L W, Viscusi E R, Groudine S B, Payen-Champenois C. Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery. Anesthesiology 2005; 102(4): 822–31.
    1. Singh J A. Smoking and outcomes after knee and hip arthroplasty: a systematic review. J Rheumatol 2011; 38(9): 1824–34.
    1. Smith T O, Hing C B. Is a tourniquet beneficial in total knee replacement surgery? A meta-analysis and systematic review. Knee 2010; 17(2): 141–7.
    1. Smith I, Kranke P, Murat I, Smith A, O’Sullivan G, Soreide E, Spies C, in’t Veld B, European Societyof A. Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol 2011; 28(8): 556–69.
    1. Smith M D, McCall J, Plank L, Herbison G P, Soop M, Nygren J. Preoperative carbohydrate treatment for enhancing recovery after elective surgery. Cochrane Database Syst Rev 2014(8): CD009161.
    1. Soop M, Nygren J, Thorell A, Weidenhielm L, Lundberg M, Hammarqvist F, Ljungqvist O. Preoperative oral carbohydrate treatment attenuates endogenous glucose release 3 days after surgery. Clin Nutr 2004; 23(4): 733–41.
    1. Spahn D R. Anaemia and patient blood management in hip and knee surgery: a systematic review of the literature. Anesthesiology 2010; 113(2): 482–95.
    1. Specht K, Kjaersgaard-Andersen P, Pedersen B D. Nursing in fast-track total hip and knee arthroplasty: a retrospective study. Int J Orthop Trauma Nurs 2015; 19(3): 121–30.
    1. Specht K, Kjaersgaard-Andersen P, Pedersen B D. Patient experience in fast-track hip and knee arthroplasty: a qualitative study. J Clin Nurs 2016; 25(5-6): 836–45.
    1. Sprowson A, McNamara I, Manktelow A. Enhanced recovery pathway in hip and knee arthroplasty: “fast track” rehabilitation 2013; 27(5): 296–302.
    1. Temple-Oberle C, Shea-Budgell M A, Tan M, Semple J L, Schrag C, Barreto M, Blondeel P, Hamming J, Dayan J, Ljungqvist O, Society E. Consensus review of optimal perioperative care in breast reconstruction: Enhanced Recovery after Surgery (ERAS) Society recommendations. Plast Reconstr Surg 2017; 139(5): 1056e–71e.
    1. Theusinger O M, Kind S L, Seifert B, Brogeat I, Gerber C, Spahn D R. Patient blood management in orthopaedic surgery: a four-year follow-up of transfusion requirements and blood loss from 2008-2011 at the Balgrist University Hospital in Zurich, Switzerland. Blood Transfus 2014; 12(2): 195–203.
    1. Thomsen T, Villebro N, Moller A M. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev 2014(3): CD002294.
    1. Thorell A, MacCormick A D, Awad S, Reynolds N, Roulin D, Demartines N, Vignaud M, Alvarez A, Singh P M, Lobo D N. Guidelines for perioperative care in bariatric surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations. World J Surg 2016; 40(9): 2065–83.
    1. Venclauskas L, Llau J V, Jenny J Y, Kjaersgaard-Andersen P, Jans Ø; ESA VTE Guidelines Task Force. European guidelines on perioperative venous thromboembolism prophylaxis: Day surgery and fast-track surgery. Eur J Anaesthesiol 2018; 35(2): 134–8.
    1. Voigt J, Mosier M, Darouiche R. Systematic review and meta-analysis of randomized controlled trials of antibiotics and antiseptics for preventing infection in people receiving primary total hip and knee prostheses. Antimicrob Agents Chemother 2015; 59(11): 6696–707.
    1. Wainwright T W, Kehlet H. Fast-track hip and knee arthroplasty: have we reached the goal? Acta Orthop 2019; 90(1): 3–5. 2018.1550708.
    1. Wainwright T W, Middleton R M. An orthopaedic enhanced recovery pathway. Curr Anaesth Crit Care 2010; 21(3): 114–20. 2010.01.003.
    1. Wang L, Lee M, Zhang Z, Moodie J, Cheng D, Martin J. Does preoperative rehabilitation for patients planning to undergo joint replacement surgery improve outcomes? A systematic review and meta-analysis of randomised controlled trials. BMJ Open 2016; 6(2): e009857.
    1. Yun X-D, Yin X-L, Jiang J, Teng Y-Y, Dong H-T, An L-P, Xia, Y-Y. Local infiltration analgesia versus femoral nerve block in total knee arthroplasties: a meta-analysis. Orthop Traumatol Surg Res 2015; 101(5): 565–569.
    1. Zhai L, Song Z, Liu K. the effect of gabapentin on acute postoperative pain in patients undergoing total knee arthroplasty: a meta-analysis. Medicine (Baltimore) 2016; 95(20): e3673.
    1. Zhang W, Li N, Chen S, Tan Y, Al-Aidaros M, Chen L. The effects of a tourniquet used in total knee arthroplasty: a meta-analysis. J Orthop Surg Res 2014; 9(1): 13.
    1. Zhang P, Li J, Wang X. Combined versus single application of tranexamic acid in total knee and hip arthroplasty: a meta-analysis of randomized controlled trials. Int J Surg 2017; 43: 171–80.
    1. Zhang Q, Liu L, Sun W, Gao F, Zhang Q, Cheng L, Li Z. Are closed suction drains necessary for primary total knee arthroplasty? A systematic review and meta-analysis. Medicine (Baltimore) 2018; 97(30): e11290.
    1. Zimmerli W, Trampuz A, Ochsner P E. Prosthetic-joint infections. N Engl J Med 2004; 351(16): 1645–54.

Source: PubMed

3
Abonnieren