Lesion Sterilization and Tissue Repair-Current Concepts and Practices

Shaniya Sain, Reshmi J, Anandaraj S, Sageena George, Jyoti S Issac, Sheen A John, Shaniya Sain, Reshmi J, Anandaraj S, Sageena George, Jyoti S Issac, Sheen A John

Abstract

A deciduous tooth affected by dental caries involving the pulp tissue with subsequent periradicular pathosis at times makes the conventional endodontic procedures a dilemma for a variety of reasons. In this situation, lesion sterilization and tissue repair (LSTR) stands out as the only option by which dentists could increase the longevity of the deciduous teeth of a young child. This therapy aims to eliminate bacteria from the root canals by sterilizing the lesion and promoting tissue repair and regeneration by the host's natural tissue responses. This article reviews the rationale, indications, contraindications and the procedure in detail. How to cite this article: Sain S, Reshmi J, Anandaraj S, George S, Issac JS, John SA. Lesion Sterilization and Tissue Repair-Current Concepts and Practices, Int J Clin Pediatr Dent. 2018;11(5):446-450.

Keywords: 3-Mix paste; Lesion sterilization and tissue repair; Triple-antibiotic paste.

Conflict of interest statement

Source of support: Nil Conflict of interest: None

References

    1. Takushige T, Cruz EV, Moral AA, Hoshino E. Endodontic treatment of primary teeth using a combination of antibacterial drugs. IntEndod J. 2004;37:132–138.
    1. Cohen M, Burns RC. Path ways of pulp, 8th ed. St. Louis: Mosby Inc; 2002.
    1. Finn SB. Clinical pedodontics . 4th ed. Philadelphia: W.B. Saunders Company; 1995.
    1. American Academy of Pediatric Dentistry. Guideline on management of developing dentition and occlusion in pediatric dentistry. Pediatr Dent. 2012;34:239–251.
    1. Belanger C. Pulp therapy for the primary dentition. Pediatr Dent. 1988;10:257–267.
    1. Hoshino E, Kurihara-Ando N, Sato I, Uematsu H, Sato M, Kota K et al. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. International endodontic journal. 1996;29(2):125–130.
    1. Sato T, Hoshino E, Uematsu H, Noda T. In vitro antimicrobial susceptibility to combinations of drugs of bacteria from carious and endodontic lesions of human deciduous teeth. Oral Microbial Immunol. 1993;8:172–176.
    1. Sato I, Ando-Kurihara N, Kota K, Iwaku M, Hoshino E. Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in . situ. International endodontic journal. 1996;29(2):118–124.
    1. Kim J, Kim Y, Shin S, Park J, Jung I. Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod. 2010;36:1086–1091.
    1. Anila B, Murali H, Cheranjeevi J, Kapil RS. Lesion Sterilization and Tissue Repair (LSTR): . A Review J scientific dentistry. 2014;4(2):49–55.
    1. Cruz EV, Kota K, Huque J, Iwaku M, Hoshino E. Penetration of propylene glycol into dentine. IntEndod J. 2002;35:330–336.
    1. Prabhakar AR, Sridevi E, Raju OS, Satish V. Endodontic treatment of primary teeth using combination of antibacterial drugs: an in vivo study. J Indian Soc Pedod Prev Dent. 2008;26:5–10.
    1. Banchs F, Trope M. Revascularization of immature permanent teeth with apical Periodontitis: new treatment protocol? . J Endod. 2004;30:196–200.
    1. Kayalvizhi G, Subramaniyan B, Suganya G. Topical application of antibiotics in primary teeth: an overview. Journal of Dentistry for Children. 2013;80(2):71–79.
    1. Jaya AR, Praveen P, Anantharaj A, Venkataraghavan K, Rani PS. In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations. J Clin Pediatr Dent. 2012 Winter;37(2):189–191.
    1. Burrus D, Barbeau L, Hodgson B. Treatment of abscessed primary molars utilizing lesion sterilization and tissue repair: literature review and report of three cases. Pediatric dentistry. 2014;36(3):240–244.
    1. Trairatvorakul C, Detsomboonrat P. Success rates of a mixture of ciprofloxacin, metronidazole, and minocycline antibiotics used in the non-instrumentation endodontic treatment of mandibular primary molars with carious pulpal involvement. Int J paediatr dent. 2012 May;22(3):217–227.
    1. Nakornchai S, Banditsing P, Visetratana N. Clinical evaluation of 3 Mix and Vitapex as treatment options for pulpally involved primary molars. Int J Paediatr Dent. 2010 May;20(3):214–221.
    1. Pinky C, Shashibhushan KK, Subbareddy VV. Endodontic treatment of necrosed primary teeth using two different combinations of antibacterial drugs: An in vivo study. J Indian Soc Pedod Prev Dent. 2011;29:121–127.
    1. Agarwal M, Das UM, Vishwanath D. A comparative evaluation of noninstrumentation endodontic techniques with conventional ZOE pulpectomy in deciduous molars: an in vivo study. World J Dentistry. 2011;2(3):187–192.
    1. Alam T, Nakazawa F, Nakajo K, Uematsu H, Hoshino E. Susceptibility of Enterococcus faecalis to a combination of antibacterial drugs (3-mix) in vitro. J Oral Biosci. 2005;47:315–320.
    1. Windley W III, Teixeira F, Levin L, Sigurdsson A, Trope M. Disinfection of immature teeth with triple antibiotic paste. J Endod. 2005;31:439–443.
    1. Lenherr P, Allgayer N, Weiger R, Filippi A, Attin T, Krastl G. Tooth discoloration induced by endodontic materials: a laboratory study. International endodontic journal. 2012;45(10):942–949.

Source: PubMed

Sponsoren und Mitarbeiter

Krankheiten

Drogeninterventionen

3
Abonnieren