Platelet Rich Plasma: a short overview of certain bioactive components

Voja Pavlovic, Milan Ciric, Vladimir Jovanovic, Predrag Stojanovic, Voja Pavlovic, Milan Ciric, Vladimir Jovanovic, Predrag Stojanovic

Abstract

Platelet rich plasma (PRP) represents a relatively new approach in regenerative medicine. It is obtained from patient's own blood and contains different growth factors and other biomolecules necessary for wound healing. Since there are various protocols for PRP preparing, it usually results with PRP generation with different amounts of bioactive substances, which finally may modulate the intensity of wound healing. The reference data about potential effect of some PRP compounds on wound healing, in different tissues, are still controversial. This review summarizes recently known facts about physiological role of certain PRP components and guidance for further research. Also, this review discusses different procedure for PRP generation and potential effect of leukocytes on wound healing.

Keywords: Growth factors; Leukocytes; Platelet rich plasma; Platelets; Wound healing.

Conflict of interest statement

Authors state no conflict of interest.

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Source: PubMed

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