Predominantly nighttime feeding and weight outcomes in infants

Tuck Seng Cheng, See Ling Loy, Jia Ying Toh, Yin Bun Cheung, Jerry Kok Yen Chan, Keith M Godfrey, Peter D Gluckman, Seang Mei Saw, Yap-Seng Chong, Yung Seng Lee, Ngee Lek, Mary Foong-Fong Chong, Fabian Yap, Tuck Seng Cheng, See Ling Loy, Jia Ying Toh, Yin Bun Cheung, Jerry Kok Yen Chan, Keith M Godfrey, Peter D Gluckman, Seang Mei Saw, Yap-Seng Chong, Yung Seng Lee, Ngee Lek, Mary Foong-Fong Chong, Fabian Yap

Abstract

Background: The influence of circadian feeding patterns on weight outcomes has been shown in animal and human studies but not in very young children.

Objective: We aimed to examine the association of infant circadian feeding patterns at 12 mo of age with subsequent growth and weight status after 1 y.

Design: Mothers from a Singapore birth cohort (n = 349) reported the food given to their infants and the feeding time at 12 mo of age. Predominantly daytime (pDT) (0700-1859; n = 282) and predominantly nighttime (pNT) (1900-0659; n = 67) feeding infants were defined by whether daytime energy intake was >50% or <50% of total energy intake as assessed with the use of a 24-h recall. Body mass index-for-age z scores (BAZs) were computed with the use of the WHO Child Growth Standards 2006 to determine changes in BAZs from 12 to 24 mo of age and weight status at 24 mo of age. Multivariable linear and logistic regression analyses were performed.

Results: Compared with pDT feeding, pNT feeding was associated with a higher BAZ gain from 12 to 24 mo of age (adjusted β = 0.38; 95% CI: 0.11, 0.65; P = 0.006) and increased risk of becoming overweight at 24 mo of age (adjusted OR: 2.78; 95% CI: 1.11, 6.97; P = 0.029) with adjustments for maternal age, education, ethnicity, monthly household income, parity, infant BAZ at 12 mo of age, feeding mode in the first 6 mo of life, and total daily energy intake.

Conclusions: Our study suggests that the role of the daily distribution of energy consumption in weight regulation begins in infancy. The feeding of infants predominantly during nighttime hours was associated with adiposity gain and risk of overweight in early childhood. The inclusion of advice on the appropriate feeding time may be considered when implementing strategies to combat childhood obesity. This trial was registered at clinicaltrials.gov as NCT01174875.

Keywords: adiposity; circadian; feeding; infant; nighttime; overweight.

© 2016 American Society for Nutrition.

References

    1. Mol Cell Endocrinol. 2012 Feb 5;349(1):68-75
    1. Obesity (Silver Spring). 2013 Dec;21(12):2504-12
    1. Nutr Res Rev. 2014 Jun;27(1):107-18
    1. Chronobiol Int. 2012 Aug;29(7):920-7
    1. Clin Nutr Res. 2013 Jul;2(2):81-90
    1. Curr Biol. 2013 Aug 19;23(16):1554-8
    1. Int J Obes (Lond). 2015 May;39(5):828-33
    1. Cochrane Database Syst Rev. 2013 Mar 28;(3):CD009275
    1. Br J Nutr. 2012 Oct;108(7):1286-91
    1. Diabetes. 2012 Nov;61(11):2691-700
    1. Diabetes. 1992 Jun;41(6):750-9
    1. PLoS One. 2013;8(3):e56519
    1. J Endocrinol. 2014 Aug;222(2):R75-96
    1. Am J Clin Nutr. 2003 May;77(5):1171-8
    1. N Engl J Med. 2008 May 8;358(19):1991-2002
    1. Curr Obes Rep. 2014 Mar;3(1):101-7
    1. Curr Nutr Rep. 2014 Apr 27;3:204-212
    1. Lancet. 2004 Jan 10;363(9403):157-63
    1. Int J Obes (Lond). 2013 Apr;37(4):604-11
    1. Int J Epidemiol. 2014 Oct;43(5):1401-9
    1. J Clin Endocrinol Metab. 2014 Jan;99(1):240-7
    1. Matern Child Nutr. 2016 Oct;12(4):688-98
    1. PLoS One. 2015 Nov 16;10(11):e0142239
    1. Am J Epidemiol. 2011 Mar 15;173(6):649-58
    1. Reproduction. 2010 Sep;140(3):365-71
    1. Am J Clin Nutr. 1997 Apr;65(4 Suppl):1220S-1228S; discussion 1229S-1231S
    1. Psychiatry Res. 1989 May;28(2):193-213
    1. Diabetes Care. 1996 Apr;19(4):333-40
    1. BMJ. 1990 Jan 27;300(6719):230-5
    1. Matern Child Health J. 2015 Nov;19(11):2523-35

Source: PubMed

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