Demographic profile and outcome analysis of a tertiary level pediatric intensive care unit

Praveen Khilnani, Devajit Sarma, Reeta Singh, Rajiv Uttam, Shiv Rajdev, Archana Makkar, Jyotinder Kaur, Praveen Khilnani, Devajit Sarma, Reeta Singh, Rajiv Uttam, Shiv Rajdev, Archana Makkar, Jyotinder Kaur

Abstract

Objective: To study the profile and outcome of children admitted to a tertiary level pediatric intensive care unit (PICU) in India.

Methods: Prospective study of patient demographics, PRISM III scores, diagnoses, treatment, morbidity and mortality of all PICU admissions.

Results: 948 children were admitted to the PICU. Mean age was 41.48 months. Male to female ratio was 2.95:1. Mean PRISM III score on admission was 18.50. Diagnoses included respiratory (19.7%), cardiac (9.7%), neurological (17.9%), infectious (12.5%), trauma (11.7%), other surgical (8.8%).196 children (20.68%) required mechanical ventilation. Average duration of ventilation was 6.39 days. 27 children (30.7 children /1000 admissions) had acute respiratory distress syndrome. Gross mortality was 6.7% (59 patients). PRISMIII adjusted mortality was directly proportional to PRISMIII scores. 49.5% of nonsurvivors had multiorgan failure. Average length of PICU stay was 4.52 +/- 2.6 days. Complications commonly encountered were atelectasis (6.37%), accidental extubation (2%), and pneumothorax (0.9%). Incidence of nosocomial infections was 16.86%.

Conclusion: Our data appears to be similar with regards to PRISMIII scores and adjusted mortality, length of the PICU stay, and duration of ventilation, to previously published western data. Multiorgan failure remains a major cause of death. As expected, Dengue and malaria were common. Incidence of nosocomial infections was somewhat high. Interestingly, more boys got admitted to the PICU as compared to girls. Clearly more studies are required to assess the overall outcomes of critically ill children in India.

References

    1. Downes John J. The historical evolution, current status and prospective development of pediatric Critical care. Critical Care Clinics. 1992;8:1–65.
    1. Tilford JM, Simpson PM, Green JW, Lensing S, Fiser DH. Volume outcome relationships in pediatric Critical care units. Pediatrics. 2000;106(2):289–294. doi: 10.1542/peds.106.2.289.
    1. Tilford JM, Robertson PK, Lensing S, Fiser DH. Improvement in pediatric Critical care outcome. Crit Care Med. 2000;28(2):601–603. doi: 10.1097/00003246-200002000-00072.
    1. Pollack MM, Cuerdon TC, Getson PR. pediatric Intensive Care units : results of a national survey. Crit Care Med. 1993;21:607–613.
    1. Pollack MM, Getson PR, Ruttiman UE. Efficiency of Intensive care, a comparative analysis of eight pediatric intensive care units. JAMA. 1987;258:1481–1486. doi: 10.1001/jama.258.11.1481.
    1. Pollack MM, Katz RW, Ruttiman UE, et al. Improving the outcome and efficiency of pediatric intensive care units; the impact of an intensivist. Crit Care Med. 1988;16:11–17.
    1. Pollack MM, Patel Kantilal M, Ruttiman UE. Prism 3: An updated pediatric risk of Mortality score. Crit Care Med. 1996;24(5):743–752. doi: 10.1097/00003246-199605000-00004.
    1. Fiser DH. Assessing the outcome of pediatric Intensive Care. J Pediatr. 1992;121:68–74. doi: 10.1016/S0022-3476(05)82544-2.
    1. Kapil D, Bagga A. The profile and outcome of patients admitted to a pediatric Intensive Care Unit. Indian J Pediatr. 1993;60:5–10.
    1. Parikh CR, Karnad DR. Quality cost and outcome of intensive care in a public hospital in Bombay India. Crit Care Med. 1999;27(9):1754–1759. doi: 10.1097/00003246-199909000-00009.
    1. Lodha R, Kabra SK, Pandey RM. Acute respiratory distress syndrome; Experience of a Tertiary care hospital. Indian Pediatr. 2001;38:1154–1159.
    1. Morris Earle, Octavio Martinez N, Alan Zaslavsky, et al. Outcome of pediatric intensive care at six centers in Mexico and Ecuador. Crit Care Med. 1997;25(9):1462–1467. doi: 10.1097/00003246-199709000-00011.
    1. Indian Society of Critical Care Medicine (pediatric section) and Indian Academy of Pediatrics(Intensive care chapter) Consensus Guidelines for pediatric Intensive Care units in India. Indian Pediatr. 2002;39:43–50.
    1. Bernard CR, Antigas A. The American European consensus conference on J Crit Care Med 1994; 149–152.
    1. Garner JS, Jarvis WR, Emori TG. CDC definitions for nosocomial infections. Am J Infect Control. 1988;16:128–140. doi: 10.1016/0196-6553(88)90053-3.
    1. Bradbury RC, Stearns FE, Steon PM. Interhospital variations in admission in severity-adjusted hospital mortality and morbidity. Health Serv Res. 1991;26:407–424.
    1. Greanfield S, Nelson EC, Zubkoff M. Variations in response utilizations among medical specialities and systems of care, results from medical outcomes study. JAMA. 1992;267:1624–1630. doi: 10.1001/jama.267.12.1624.
    1. Kanaus WA, Wagner DP, Zimmerman JE. Variations in mortality and length of stay from intensive care. Ann Intern Med. 1993;118:753–761.
    1. Park RE, Brook RH, Kosecoff J. Explaining variations in hospital death rates, randomness, severity of illness, quality of care. JAMA. 1990;264:484–490. doi: 10.1001/jama.264.4.484.
    1. Groger JS, Strossberg MA, Halpern NA. Description analysis of critical care units in the United States. Crit Care Med. 1992;20:846–851. doi: 10.1097/00003246-199206000-00024.
    1. Hentke M, Holzer K, Thane S, Schmondra T, Hanish E. The SOFA score in evaluating septic illness: correlation with multiorgan dysfunction and APACHE II. score. CHIRUGR(Ger) 2000;71(10):1270–1276.
    1. Chang RW, Jacobs S, Lee B. Pace and predicting deaths among intensive care unit patients. Crit Care Med. 1988;16(1):34–42. doi: 10.1097/00003246-198801000-00007.
    1. Pollack MM, Ruttimann UE, Getson PR. Accurate prediction of the outcome of pediatric intensive care, a new quantitative method. New Engl Journal Med. 1987;316:134–139. doi: 10.1056/NEJM198701153160304.
    1. Tilford JM, Robertson PK, Lensig S, et al. Differences in pediatric ICU mortality risk over time. Crit Care Med. 1998;26(10):1737–1743. doi: 10.1097/00003246-199810000-00032.
    1. Goh AY, Lum LC, Chan PW. pediatric intensive care in Kualalampur; a developing subspeciality. J Trop Pediatr. 1999;45(6):362–364. doi: 10.1093/tropej/45.6.362.
    1. Hollbrook PR, Taylor G, Pollack MM, et al. Adult respiratory distress syndrome in children. Pediatr Clin North Am. 1989;27:667–685.
    1. Lyvene RK, Trough WE. Adult respiratory distress syndrome in pediatric Intensive Care Unit, predisposing condition, clinical course and outcome. Pediatrics. 1981;67:790–795.
    1. Correia M, Simao C, Lito LM, et al. Nosocomial infection in a pediatric intensive care unit. Acta Med Port. 1997;10(6–7):463–468.
    1. Stein F, Trevino R. Nosocomial infections in the pediatric intensive care unit. Pediatr Clin North Am. 1994;41(6):1245–1257.
    1. Khuri-Bulos NA, Sherman M, Agabi S, et al. Nosocomial infections in Intensive care units at a university hospital in a developing country: comparison with national nosocomial infection surveillance intensive care unit rates. Am J Infect Control. 1999;27(6):547–552. doi: 10.1016/S0196-6553(99)70035-0.

Source: PubMed

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