Barriers and facilitators to adopting high value practices and de-adopting low value practices in Canadian intensive care units: a multimethod study
Khara Sauro, Sean M Bagshaw, Daniel Niven, Andrea Soo, Rebecca Brundin-Mather, Jeanna Parsons Leigh, Deborah J Cook, Henry Thomas Stelfox, Khara Sauro, Sean M Bagshaw, Daniel Niven, Andrea Soo, Rebecca Brundin-Mather, Jeanna Parsons Leigh, Deborah J Cook, Henry Thomas Stelfox
Abstract
Objective: To compare and contrast illustrative examples of the adoption of high value practices and the de-adoption of low value practices.
Design: (1) Retrospective, population-based audit of low molecular weight heparin (LMWH) for venous thromboembolism (VTE) prophylaxis (high value practice) and albumin for fluid resuscitation (low value practice) and (2) cross-sectional survey of healthcare providers.
Setting: Data were collected from nine adult medical-surgical intensive care units (ICUs) in two large Canadian cities. Patients are managed in these ICUs by a group of multiprofessional and multidisciplinary healthcare providers.
Participants: Participants included 6946 ICU admissions and 309 healthcare providers from the same ICUs.
Main outcome measures: (1) The use of LMWH for VTE prophylaxis (per cent ICU days) and albumin for fluid resuscitation (per cent of patients); and (2) provider knowledge of evidence underpinning these practices, and barriers and facilitators to adopt and de-adopt these practices.
Results: LMWH was administered on 38.7% of ICU days, and 20.0% of patients received albumin.Most participants had knowledge of evidence underpinning VTE prophylaxis and fluid resuscitation (59.1% and 84.2%, respectively). Providers perceived these practices to be followed. The most commonly reported barrier to adoption was insufficient knowledge/understanding (32.8%), and to de-adoption was clinical leader preferences (33.2%). On-site education was the most commonly identified facilitator for adoption and de-adoption (67.8% and 68.6%, respectively).
Conclusions: Despite knowledge of and self-reported adherence to best practices, the audit demonstrated opportunity to improve. Provider-reported barriers and facilitators to adoption and de-adoption are broadly similar.
Keywords: appropriateness; healthcare system; intensive care; quality improvement; under-use and over-use.
Conflict of interest statement
Competing interests: None declared.
© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
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References
- Institute of Medicine. Crossing the Quality Chiasm. Washington, DC, 2001.
- Niven DJ, Rubenfeld GD, Kramer AA, et al. . Effect of published scientific evidence on glycemic control in adult intensive care units. JAMA Intern Med 2015;175:801–9. 10.1001/jamainternmed.2015.0157
- McGlynn EA, Asch SM, Adams J, et al. . The quality of health care delivered to adults in the United States. N Engl J Med 2003;348:2635–45. 10.1056/NEJMsa022615
- Rogers EM. Lessons for guidelines from the diffusion of innovations. Jt Comm J Qual Improv 1995;21:324–8.
- Graham ID, Logan J, Harrison MB, et al. . Lost in knowledge translation: time for a map? J Contin Educ Health Prof 2006;26:13–24. 10.1002/chp.47
- McCormack B, Kitson A, Harvey G, et al. . Getting evidence into practice: the meaning of ’context'. J Adv Nurs 2002;38:94–104.
- Cabana MD, Rand CS, Powe NR, et al. . Why don’t physicians follow clinical practice guidelines? A framework for improvement. JAMA 1999;282:1458–65.
- Niven DJ, Mrklas KJ, Holodinsky JK, et al. . Towards understanding the de-adoption of low-value clinical practices: a scoping review. BMC Med 2015;13:255 10.1186/s12916-015-0488-z
- van Bodegom-Vos L, Davidoff F, Marang-van de Mheen PJ. Implementation and de-implementation: two sides of the same coin? BMJ Qual Saf 2017;26:495–501. 10.1136/bmjqs-2016-005473
- Rogers EM. The innovation-decision process. Diffusion of Innovations. 5 ed New York, NY: Free Press, 2003.
- Prasad V, Ioannidis JP. Evidence-based de-implementation for contradicted, unproven, and aspiring healthcare practices. Implement Sci 2014;9:1 10.1186/1748-5908-9-1
- Montini T, Graham ID. "Entrenched practices and other biases": unpacking the historical, economic, professional, and social resistance to de-implementation. Implement Sci 2015;10:24 10.1186/s13012-015-0211-7
- Davidoff F. On the undiffusion of established practices. JAMA Intern Med 2015;175:809–11. 10.1001/jamainternmed.2015.0167
- Al-Ani F, Shariff S, Siqueira L, et al. . Identifying venous thromboembolism and major bleeding in emergency room discharges using administrative data. Thromb Res 2015;136:1195–8. 10.1016/j.thromres.2015.10.035
- Macleod MR, Michie S, Roberts I, et al. . Biomedical research: increasing value, reducing waste. Lancet 2014;383:101–4. 10.1016/S0140-6736(13)62329-6
- Grady D, Redberg RF. Less is more: how less health care can result in better health. Arch Intern Med 2010;170:749–50. 10.1001/archinternmed.2010.90
- Fowler RA, Mittmann N, Geerts W, et al. . Cost-effectiveness of dalteparin vs unfractionated heparin for the prevention of venous thromboembolism in critically ill patients. JAMA 2014;312:2135–45. 10.1001/jama.2014.15101
- Hirsh J, Raschke R. Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004;126(3 Suppl):188s–203. 10.1378/chest.126.3_suppl.188S
- Li G, Cook DJ, Levine MA, et al. . Competing risk analysis for evaluation of dalteparin versus unfractionated heparin for venous thromboembolism in medical-surgical critically Ill patients. Medicine 2015;94:e1479 10.1097/MD.0000000000001479
- Alberta Health Services. Venous thromboembolism prophylaxis (document #PS09-01). 2016. .
- Rhodes A, Evans LE, Alhazzani W, et al. . Surviving sepsis campaign: International guidelines for management of sepsis and septic shock: 2016. Crit Care Med 2017;45:486–552. 10.1097/CCM.0000000000002255
- Finfer S, Bellomo R, Boyce N, et al. . A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004;350:2247–56. 10.1056/NEJMoa040232
- Lyu PF, Hockenberry JM, Gaydos LM, et al. . Impact of a sequential intervention on albumin utilization in critical Care. Crit Care Med 2016;44:1307–13. 10.1097/CCM.0000000000001638
- Navickis RJ, Greenhalgh DG, Wilkes MM. Albumin in burn shock resuscitation: a meta-analysis of controlled clinical studies. J Burn Care Res 2016;37:e268–78. 10.1097/BCR.0000000000000201
- Patel A, Laffan MA, Waheed U, et al. . Randomised trials of human albumin for adults with sepsis: systematic review and meta-analysis with trial sequential analysis of all-cause mortality. BMJ 2014;349:g4561 10.1136/bmj.g4561
- European Association for the Study of the Liver. EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis. J Hepatol 2010;53:397–417. 10.1016/j.jhep.2010.05.004
- Bernardi M, Caraceni P, Navickis RJ, et al. . Albumin infusion in patients undergoing large-volume paracentesis: a meta-analysis of randomized trials. Hepatology 2012;55:1172–81. 10.1002/hep.24786
- Cavallin M, Kamath PS, Merli M, et al. . Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial. Hepatology 2015;62:567–74. 10.1002/hep.27709
- Salerno F, Navickis RJ, Wilkes MM. Albumin infusion improves outcomes of patients with spontaneous bacterial peritonitis: a meta-analysis of randomized trials. Clin Gastroenterol Hepatol 2013;11:123–30. 10.1016/j.cgh.2012.11.007
- Cook D, Duffett M, Lauzier F, et al. . Barriers and facilitators of thromboprophylaxis for medical-surgical intensive care unit patients: a multicenter survey. J Crit Care 2014;29:471.e1–471.e9. 10.1016/j.jcrc.2014.01.017
- Parsons Leigh J, Niven DJ, Boyd JM, et al. . Developing a framework to guide the de-adoption of low-value clinical practices in acute care medicine: a study protocol. BMC Health Serv Res 2017;17:54 10.1186/s12913-017-2005-x
- Stelfox HT, Niven DJ, Clement FM, et al. . Stakeholder Engagement to Identify Priorities for Improving the Quality and Value of Critical Care. PLoS One 2015;10:e0140141 10.1371/journal.pone.0140141
- Sinuff T, Muscedere J, Adhikari NK, et al. . Knowledge translation interventions for critically ill patients: a systematic review*. Crit Care Med 2013;41:2627–40. 10.1097/CCM.0b013e3182982b03
- Gershengorn HB, Wunsch H. Understanding changes in established practice: pulmonary artery catheter use in critically ill patients. Crit Care Med 2013;41:2667–76. 10.1097/CCM.0b013e318298a41e
- Koo KK, Sun JC, Zhou Q, et al. . Pulmonary artery catheters: evolving rates and reasons for use. Crit Care Med 2011;39:1613–8. 10.1097/CCM.0b013e318218a045
- Murphy DJ, Needham DM, Netzer G, et al. . RBC transfusion practices among critically ill patients: has evidence changed practice?. Crit Care Med 2013;41:2344–53. 10.1097/CCM.0b013e31828e9a49
- Wiener RS, Welch HG. Trends in the use of the pulmonary artery catheter in the United States, 1993-2004. JAMA 2007;298:423–9. 10.1001/jama.298.4.423
- Munshi L, Gershengorn HB, Fan E, et al. . Adjuvants to mechanical ventilation for acute respiratory failure. Adoption, de-adoption, and factors associated with selection. Ann Am Thorac Soc 2017;14:94–102. 10.1513/AnnalsATS.201606-438OC
- Kahn JM, Le TQ, Tq L. Adoption and de-adoption of drotrecogin alfa for severe sepsis in the United States. J Crit Care 2016;32:114–9. 10.1016/j.jcrc.2015.12.007
- Melnyk BM. Culture eats strategy every time: What works in building and sustaining an evidence-based practice culture in healthcare systems. Worldviews Evid Based Nurs 2016;13:99–101. 10.1111/wvn.12161
- Dodek P, Cahill NE, Heyland DK. The relationship between organizational culture and implementation of clinical practice guidelines: a narrative review. JPEN J Parenter Enteral Nutr 2010;34:669–74. 10.1177/0148607110361905
- Menear M, Grindrod K, Clouston K, et al. . Advancing knowledge translation in primary care. Can Fam Physician 2012;58:623e302–7.
- Scott IA, Elshaug AG. Foregoing low-value care: how much evidence is needed to change beliefs? Intern Med J 2013;43:107–9. 10.1111/imj.12065
- Lauzier F, Muscedere J, Deland E, et al. . Thromboprophylaxis patterns and determinants in critically ill patients: a multicenter audit. Crit Care 2014;18:R82 10.1186/cc13844
- Cook D, Meade M, Guyatt G, et al. . Dalteparin versus unfractionated heparin in critically ill patients. N Engl J Med 2011;364:1305–14. 10.1056/NEJMoa1014475
- Alhazzani W, Lim W, Jaeschke RZ, et al. . Heparin thromboprophylaxis in medical-surgical critically ill patients: a systematic review and meta-analysis of randomized trials. Crit Care Med 2013;41:2088–98. 10.1097/CCM.0b013e31828cf104
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