A randomized clinical trial of theory-based activities for the behavioral symptoms of dementia in nursing home residents

Abstract

Objectives: To test the main and interactive effects of activities derived from the Need-Driven Dementia-Compromised Behavior model for responding to behavioral symptoms in nursing home residents.

Design: Randomized double-blind clinical trial.

Setting: Nine community-based nursing homes.

Participants: One hundred twenty-eight cognitively impaired residents randomly assigned to activities adjusted to functional level (FL) (n=32), personality style of interest (PSI) (n=33), functional level and personality style of interest (FL+PSI) (n=31), or active control (AC) (n=32).

Intervention: Three weeks of activities provided twice daily.

Measurements: Agitation, passivity, engagement, affect, and mood assessed from video recordings and real-time observations during baseline, intervention, random times outside of intervention, and 1 week after intervention.

Results: All treatments improved outcomes during intervention except mood, which worsened under AC. During intervention the PSI group demonstrated greater engagement, alertness, and attention than the other groups; the FL+PSI group demonstrated greater pleasure. During random times, engagement returned to baseline levels except in the FL group in which it decreased. There was also less agitation and passivity in groups with a component adjusted to PSI. One week after the intervention, mood, anxiety, and passivity improved over baseline; significantly less pleasure was displayed after withdrawal of treatment.

Conclusion: The hypothesis that activities adjusted to FL+PSI would improve behavioral outcomes to a greater extent than partially adjusted or nonadjusted activities was partially supported. PSI is a critical component of individualized activity prescription.

Trial registration: ClinicalTrials.gov NCT00388544.

Conflict of interest statement

Conflict of Interest

AK was supported by NIH grant R01 NR008910

Paul T. Costa receives royalties from the NEO-PI-R and the NEO-FFI and was supported in part by NIH Grant DAO26652

© 2011, Copyright the Authors. Journal compilation © 2011, The American Geriatrics Society.

Figures

Figure 1

Flow diagram of recruitment, enrollment, intervention delivery and number of participants who contributed data to the analysis.