Ultrasound-guided transversus abdominis plane blocks for patients undergoing laparoscopic hand-assisted nephrectomy: a randomized, placebo-controlled trial

Stephen Aniskevich, C Burcin Taner, Dana K Perry, Christopher B Robards, Steven B Porter, Colleen S Thomas, Ilana I Logvinov, Steven R Clendenen, Stephen Aniskevich, C Burcin Taner, Dana K Perry, Christopher B Robards, Steven B Porter, Colleen S Thomas, Ilana I Logvinov, Steven R Clendenen

Abstract

Postoperative pain is a common complaint following living kidney donation or tumor resection using the laparoscopic hand-assisted technique. To evaluate the potential analgesic benefit of transversus abdominis plane blocks, we conducted a randomized, double-blind, placebo-controlled study in 21 patients scheduled to undergo elective living-donor nephrectomy or single-sided nephrectomy for tumor. Patients were randomized to receive either 20 mL of 0.5% ropivacaine or 20 mL of 0.9% saline bilaterally to the transversus abdominis plane under ultrasound guidance. We found that transversus abdominis plane blocks reduced overall pain scores at 24 hours, with a trend toward decreased total morphine consumption. Nausea, vomiting, sedation, and time to discharge were not significantly different between the two study groups.

Keywords: kidney donor; nephrectomy; transversus abdominis plane block; ultrasound guidance.

References

    1. Yarwood J, Berrill A. Nerve blocks of the anterior abdominal wall. Continuing Education in Anaesthesia, Critical Care and Pain. 2010;10:182–186.
    1. Mukhtar K, Khattak I. Transversus abdominis plane block for renal transplant recipients. Br J Anaesth. 2010;104:663–664.
    1. Jankovic ZB, Pollard SG, Nachiappan MM. Continuous transversus abdominis plane block for renal transplant recipients. Anesth Analg. 2009;109:1710–1711.
    1. Hosgood SA, Thiyagarajan UM, Nicholson HF, et al. Randomized clinical trial of transversus abdominis plane block versus placebo in live donor nephrectomy. Transplantation. 2012;94:520–525.
    1. Frier NM, Murphy C, Mugawar M, et al. Transversus abdominis plane block for analgesia in renal transplantation: a randomized controlled trial. Anesth Analg. 2012;115:953–957.
    1. McDonnell JG, ODonnell B, Curley G, et al. The analgesic efficacy of transversus abdominis plane block after abdominal surgery. A prospective randomized controlled study. Anesth Analg. 2007;104:193–197.
    1. El-Dawlatly AA, Turkistani A, Kettner SC, et al. Ultrasound guided transversus abdominis plane block: description of a new technique and comparison with conventional systemic analgesia during laparoscopic cholecystectomy. Br J Anaesth. 2009;102:763–767.
    1. Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap) – a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42:377–381.
    1. Johns N, O’Neill S, Ventham N, Barron F, Brady R, Daniel T. Clinical effectiveness of transversus abdominis plane (TAP) block in abdominal surgery: a systematic review and meta-analysis. Colorectal Dis. 2012;14:e635–e642.
    1. Abdallah FW, Chan VW, Brull R. Transversus abdominis plane block. A systematic review. Reg Anesth Pain Med. 2012;37:193–209.
    1. Costello JF, Moore AR, Wieczorek PM, et al. The transversus abdominis plane block, when used as part of a multimodal regimen inclusive of intrathecal morphine, does not improve analgesia after cesarean delivery. Reg Anesth Pain Med. 2009;34:586–589.
    1. Griffths JD, Middle JV, Barron FA, et al. Transversus abdominis plane block does not provide additional benefit to multimodal analgesia in gynecological cancer surgery. Anesth Analg. 2010;111:797–801.
    1. McMorrow RC, Ni Mhuircheartaigh RJ, Ahmed KA, et al. Comparison of transversus abdominis plane block vs spinal morphine for pain relief after caesarean section. Br J Anaesth. 2011;106:706–712.
    1. Sforza M, Andejelkov K, Zaccheddu R, Nagi H, Colic M. Transversus abdominis plane block anesthesia in abdominoplasties. Plast Reconstr Surg. 2011;128:529–535.
    1. Ra YS, Kim CH, Lee GY, Han JI. The analgesic effect of the ultrasound guided transverse abdominis plane block after laparoscopic cholecystectomy. Korean J Anesthesiol. 2010;58:362–368.
    1. De Oliveira GS, Fitzgerald PC, Marcus RJ, et al. A dose ranging study of the effect of transversus abdominis block on postoperative quality of recovery and analgesia after outpatient laparoscopy. Anesth Analg. 2011;113:1218–1225.
    1. Milan ZB, Duncan B, Rewari V, et al. Subcostal transversus abdominis plane block for postoperative analgesia in liver transplant recipients. Transplant Proc. 2011;43:2687–2690.
    1. Aniskevich S, Clendenen SR, Torp KD. Bilateral transversus abdominis plane block for managing pain after pancreas transplant. Exp Clin Transplant. 2011;9:277–278.
    1. Lefrant JY, de La Coussaye JE, Ripart J, et al. The comparative electrophysiologic and hemodynamic effects of a large dose of ropivicaine and bupivacaine in anesthetized and ventilated piglets. Anesth Analg. 2001;93:1598–1605.
    1. Niraj G, Kelkar A, Jeyapalan I, et al. Comparison of analgesic efficacy of subcostal transversus plane blocks with epidural analgesia following upper abdominal surgery. Anaesthesia. 2011;66:465–471.
    1. Hebbard PD, Barrington MJ, Vasey C. Ultrasound guided continuous oblique subcostal transversus abdominus plane blockade: description of anatomy and clinical technique. Reg Anesth Pain Med. 2010;35:436–441.

Source: PubMed

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