Initial Response to Transcranial Magnetic Stimulation Treatment for Depression Predicts Subsequent Response
Michael S Kelly, Albino J Oliveira-Maia, Margo Bernstein, Adam P Stern, Daniel Z Press, Alvaro Pascual-Leone, Aaron D Boes, Michael S Kelly, Albino J Oliveira-Maia, Margo Bernstein, Adam P Stern, Daniel Z Press, Alvaro Pascual-Leone, Aaron D Boes
Abstract
This study provides support for the hypothesis that treatment response to an initial course of repetitive transcranial magnetic stimulation (rTMS) for depression predicts the magnitude of response to a subsequent course of rTMS in the setting of symptom relapse.
Keywords: Antidepressants; Depression.
Figures
a A total of 225 patient charts were reviewed, with 18 patients meeting reintroduction criteria. Two of these patients were excluded due to lack of adequate Beck Depression Inventory (BDI) data. Of 16 patients identified, 11 had a favorable response to reintroduction (>50% improvement on BDI). All 11 patients that responded to reintroduction had at least a 40% improvement in BDI scores during the initial treatment course. Treatment response, measured according to percent change in BDI, was similar between the first and second course of treatment (57.9±7.7% and 56.5±9.4%, respectively; paired-samples t test, p=0.9), and the values were significantly correlated (r=0.54, p=0.03).
Source: PubMed